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The Biology of Trypanosomes (Paperback, Softcover reprint of the original 1st ed. 1985)
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The Biology of Trypanosomes (Paperback, Softcover reprint of the original 1st ed. 1985)
Series: Current Topics in Microbiology and Immunology, 117
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African and South American trypanosomiases are notable features of
clinical and veterinary practice in their respective endemic areas
and, as such, are of considerable economic importance.
Scientifically, however, their importance ex tends beyond their
clinical significance, as the trypano somes are intriguing and
easily manipulated models for the study of the control of gene
expression, membrane chemistry, proliferation and differentiation.
It is clear from the scientific press that the rate of advance has
"hotted" up in these areas of trypanosome research over the past 5
years and so a single-topic volume within the scope of the present
series seemed timely. As ever, the final admix ture of review
topics was a compromise between what was appropriate and what was
available - fortunately with the former in vast excess. I should
like to highlight two omissions, made for en tirely different
reasons. The first is a detailed treatment of the molecular biology
of the variant surface glycopro teins of the African trypanosomes
(in particular Trypano soma brucei and T. equiperdum). This topic
has been the subject of several reviews, for example, BORST and
CROSS (1982)1 and TURNER (1982)2, and so was excluded from the
present volume. The second omission is a review of the first-class
work on genetic recombination from the group of Dr. Leo Jenni at
the Schweizerisches Tropeninsti tut, Basel. This group has used
isoenzyme markers to show that T."
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