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Interacting Protein Domains - Their Role in Signal and Energy Transduction (Paperback, Softcover reprint of the original 1st ed. 1997)
Loot Price: R2,792
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Interacting Protein Domains - Their Role in Signal and Energy Transduction (Paperback, Softcover reprint of the original 1st ed. 1997)
Series: Nato ASI Subseries H:, 102
Expected to ship within 10 - 15 working days
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This is now the fourth time that protein phosphorylation has been
the focus of a NATO Advanced Study Institute. The first meeting
with the topic "Signal Trans duction and Protein Phosphorylation"
was held on the island of Spezai, Greece, in September 1986. The
second one took place in Chateau La Londe, France, in September
1989 on "Cellular Regulation by Protein Phosphorylation," the third
one on " Tyrosine Phosphorylation/Dephosphorylation and Downstream
Signaling" was in September 1992 in Maratea, Italy. The titles of
these books clearly mirror the developments that have taken place
in the last decade. Beginning with the recognition that protein
phosphorylation is at the center of signaling -clearly established
in 1990 -it became apparent that many cellular processes are
regulated by this mode. A new focus then emerged when it was
recognized that growth factors are bound to corresponding receptors
trigger protein tyrosine phosphorylation which controls cell
prolifera tion. This was the topic of the third meeting in this
series. It is now evident that further progress depends on
understanding the three dimensional structure of the proteins
involved. It goes without saying, for example, that understanding
the location of proteins by adaptor proteins is only possible on
the basis of the three dimensional protein structure. Therefore,
the fourth meeting in this series concentrated on the protein
structure of signaling molecules as well as on the elucidation of
the principles of protein domain interactions."
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