0
Your cart

Your cart is empty

Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology

Buy Now

Immunopharmacology (Paperback, Softcover reprint of the original 2nd ed. 2016) Loot Price: R4,788
Discovery Miles 47 880
Immunopharmacology (Paperback, Softcover reprint of the original 2nd ed. 2016): Manzoor M. Khan

Immunopharmacology (Paperback, Softcover reprint of the original 2nd ed. 2016)

Manzoor M. Khan

 (sign in to rate)
Loot Price R4,788 Discovery Miles 47 880 | Repayment Terms: R449 pm x 12*

Bookmark and Share

Expected to ship within 10 - 15 working days

The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010. These events resulted in a gradually narrowing gap between early scientific knowledge and the late development of immune-based therapies. Consequently, the significance and magnitude of these advances warranted a revision of this contribution; this revised edition will provide a deeper understanding of the recent advances and discoveries related to the function of the immune response and their applications in the development of novel therapies to treat human diseases. Some of the key discoveries during the past five years include: the identification of the new subsets of helper T cells; new cytokines and their networks; and novel signal transduction mechanisms. For example, the identification of TH17 subset of helper T cells, in addition to TH1 and TH2 cells, not only advanced our understanding of the function of the basic immune response, but also raised our awareness of the possible etiology and pathogenesis of diseases such as allergy, asthma, rheumatoid arthritis, and other auto-immune/immune system based diseases. The newly identified powerful cytokine networks, that regulate both innate and acquired immune responses, emerged as a result of the finding of new cell types such as innate lymphoid cells and iNKT. Identification of the novel cytokines and their networks has advanced our knowledge of the mechanisms involved in the maintenance of tissue homeostasis, including inflammation and tissue repair during stress and injury. The development of HIV vaccines has also seen dramatic changes over the last few years. There has been a shift from a sole focus on T cell vaccines to a holistic approach that pertains to the induction of both humoral and cellular elements. This entails the induction of antibodies - both binding and neutralizing - to prevent infection. The cellular vaccination produces a safety net of CD8+ T-cell responses to suppress the replication of the virus in the infected patients, and both of the effector arms are aided by helper T cells. From the perspective of clinical applications, significant advances have also been made in: oral immunotherapy for allergic disease, the possible treatment of HIV infection, the development of new monoclonal antibodies and their fragments to treat human diseases, and immune cell based therapies for cancer.

General

Imprint: Springer International Publishing AG
Country of origin: Switzerland
Release date: June 2018
Authors: Manzoor M. Khan
Dimensions: 235 x 155 x 24mm (L x W x T)
Format: Paperback
Pages: 442
Edition: Softcover reprint of the original 2nd ed. 2016
ISBN-13: 978-3-319-80768-3
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General
Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 3-319-80768-4
Barcode: 9783319807683

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

Vaxxers - The Inside Story Of The Oxford…
Sarah Gilbert, Catherine Green Paperback R118 Discovery Miles 1 180
Handbook Of HIV Medicine
Douglas Wilson, Mark Cotton, … Paperback  (1)
R704 R651 Discovery Miles 6 510
Primary Immunodeficiency Diseases - A…
Hans D. Ochs, C.I. Edvard Smith, … Hardcover R8,443 Discovery Miles 84 430
First Do No Harm
Paracelsus Hardcover R867 Discovery Miles 8 670
Basic and Clinical Aspects of Interferon…
Hridayesh Prakash Hardcover R2,879 R2,699 Discovery Miles 26 990
The Blot Upon the Brain - Studies in…
William W (William Wotherspo Ireland Hardcover R899 Discovery Miles 8 990
Review of Insanity and Nervous Diseases…
Anonymous Hardcover R899 Discovery Miles 8 990
Interleukins - The Immune and Non-Immune…
Payam Behzadi Hardcover R3,452 R3,224 Discovery Miles 32 240
Transition from Crime to Care in…
Mohammad A Nezami Hardcover R2,889 Discovery Miles 28 890
Antimicrobial Immune Response
Maria Del Mar Ortega-Villaizan, Veronica Chico Hardcover R2,866 R2,686 Discovery Miles 26 860
If I Can't Eat Flies, What Am I?
Alicia J Pfaff Hardcover R557 Discovery Miles 5 570
Graves' Disease
Robert Gensure Hardcover R4,037 R3,764 Discovery Miles 37 640

See more

Partners