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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Molecular and Cellular Biology of Phagocytosis (Hardcover, 1st ed. 2020)
Loot Price: R4,519
Discovery Miles 45 190
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Molecular and Cellular Biology of Phagocytosis (Hardcover, 1st ed. 2020)
Series: Advances in Experimental Medicine and Biology, 1246
Expected to ship within 10 - 15 working days
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Total price: R4,539
Discovery Miles: 45 390
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Phagocytosis is the engulfment of particulate matter by cells. It
is a fundamental (and probably "primitive") cell biological process
which is important in single celled organisms such as amoeba;
multicellular animals including coelenterates; and in higher
animals. In humans and other mammals, specialised immune cells
(phagocytes) utilise phagocytosis in their crucial role of
engulfing and destroying infecting microbes. Yet, surprisingly, the
biophysics and biochemistry underlying the process has only become
clear recently with the advent of genetic manipulation and advances
in single cell imaging. In this volume, the aim is to bring
together recent fundamental advances that give a clear picture of
the underlying mechanism involved in phagocytosis. Not only is this
an important topic in its own right, but a full understanding of
the process will have a potential impact on human medicine, since
as antibiotics become less effective in fight infection,
researchers are looking at alternative approaches, including
enhancing the "natural" immunity brought about by immune
phagocytes. The aim is to provide a comprehensive volume on the
topic, with separate chapters on identified recent advances, each
written by the major contributors in each area. In addition, the
volume will attempt to give a wider overview than is often the case
in single author reviews, with an emphasis here on the cell
biological understanding of phagocytosis using biophysical
approaches alongside the biochemical and imaging approaches.
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