Design of Enzyme Inhibitors as Drugs, Volume 2 (Hardcover)

A high proportion of drugs currently coming to market exert their action in the body by inhibiting a target enzyme involved in a particular body function or in a bacterium, protozoon, or virus causing an infection. This book extends the previous volume in providing a comprehensive coverage of< br> more recently recognized target enzymes and their known inhibitors and, within this framework of knowledge, demonstrates how the drug designer uses all available information to develop a specific therapeutic agent. Drug design is an interdisciplinary art; this text illustrates the pathway followed< br> from the initial design concept and synthesis of an inhibitor, through its in vitro and in vivo assessments, to clinical trial -- a process involving chemists, biochemists, pharmacologists, and clinicians.

General

Imprint:	Oxford UniversityPress
Country of origin:	United Kingdom
Release date:	April 1994
Editors:	Merton Sandler (Professor of Chemical Pathology, Royal Postgraduate Medical School) • H. John Smith (Senior Lecturer in Medicinal Chemistry, Welsh School of Pharmacy)
Dimensions:	237 x 165 x 54mm (L x W x T)
Format:	Hardcover
Pages:	848
ISBN-13:	978-0-19-262134-4
Categories:	Books > Science & Mathematics > Science: general issues > Industrial applications of scientific research & technological innovation Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > Chemotherapy
LSN:	0-19-262134-3
Barcode:	9780192621344

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