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Macrophages and Related Cells (Paperback, Softcover reprint of the original 1st ed. 1993)
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Macrophages and Related Cells (Paperback, Softcover reprint of the original 1st ed. 1993)
Series: Blood Cell Biochemistry, 5
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Total price: R5,528
Discovery Miles: 55 280
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To produce a comprehensive overview of macrophages and related cell
types in a short review volume is an impossible task. When I
selected the topics to be included, some equally important areas
were omitted by necessity, and for this I apologize. My choices
have been somewhat eclectic, touching subjects of personal interest
(such as osteoclast biology and macrophage electrophysiology) or of
current fashion (apopto sis, antigen processing, cell adhesion
molecules). The book has also had to encompass areas of a more
general flavor to provide balance for the general reader (such as
reviews of macrophage development, heterogeneity, and function, and
of the surface molecules expressed by macrophages). I thank all the
authors for their prompt sub missions; all have been of high
quality, and my editorial tasks, thankfully, have been minimal.
Michael A. Horton London, United Kingdom ix Contents Chapter J An
Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon
1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
2. The Mononuclear Phagocyte System . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . 2 3. Diversity of Macrophage
Plasma Membrane Receptors. . . . . . . . . . . . . . . . 6 3. 1 A
Structural Approach to Classification . . . . . . . . . . . . . . .
. . . . . . . . . . . 6 . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . 8 3. 2 Multisubunit Receptors
3. 3 Soluble Receptors . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . 9 3. 4 Lectins
and Lectin-Like Receptors. . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . 12 4. Functions and Selected Examples. . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
4. 1 Growth, Differentiation, and Modulation . . . . . . . . . . .
. . . . . . . . . . . . . 14 4. 2 Cell-Cell and Cell-Matrix
Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . .
16 4. 3 Endocytosis and Scavenger Receptors. . . . . . . . . . . .
. . . . . . . . . . . . . . . . 16 4. 4 Secretory Responses and
Biosynthesis of Effector Molecules . . . . . . 17 5. Concluding
Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . 17 6. References. . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
18 . . . . . . . . . . . . . . . . . . . .
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