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Macromolecular Crystallization and Crystal Perfection (Hardcover)
Loot Price: R4,561
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Macromolecular Crystallization and Crystal Perfection (Hardcover)
Series: International Union of Crystallography Monographs on Crystallography, 24
Expected to ship within 12 - 19 working days
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The crystallization of proteins and nucleic acids and/or their
complexes has become more highly automated but is still often a
trial and error based approach. In parallel, a number of X-ray
diffraction based techniques have been developed which explain the
physical reasons limiting the resulting crystallographic data and
thus show how that data may be improved. Crystal growth is also
pivotal in neutron crystallography, which establishes the hydrogen
and hydration aspects. Thus this book is aimed at addressing the
science behind obtaining the best and most complete structural data
possible for biological macromolecules, so that the detailed
structural biology and chemistry of these important molecules
emerge. Crystal imperfections such as twinning and lattice
disorders, as well as multiple crystal situations, and their
possible remedies, are also described. The small crystal frontier
in micro-crystal crystallography, crystallites in powders and
finally down to the proposed single molecule structure
determination of X-ray lasers are covered. Overall this
interdisciplinary book will interest crystal growers, X-ray and
neutron physicists and the biological crystallographers, including
graduate students.
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