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Sedimentation Velocity Analytical Ultracentrifugation - Interacting Systems (Hardcover)
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Sedimentation Velocity Analytical Ultracentrifugation - Interacting Systems (Hardcover)
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Analytical ultracentrifugation is one of the most powerful solution
techniques for the study of macromolecular interactions, to define
the number and stoichiometry of complexes formed, and to measure
affinities ranging from very strong to very weak and repulsive.
Building on the data analysis tools described in the volume
Sedimentation Velocity Analytical Ultracentrifugation: Discrete
Species and Size-Distributions of Macromolecules and Particles, and
the experimental and instrumental aspects in the first volume Basic
Principles of Analytical Ultracentrifugation, the present volume
Sedimentation Velocity Analytical Ultracentrifugation: Interacting
Systems is devoted to the theory and practical data analysis of
dynamically coupled sedimentation processes. This volume is
designed to fill a gap in biophysical methodology to provide a
framework that builds on the fundamentals of the highly developed
traditional methods of analytical ultracentrifugation, updated with
current methodology and from a viewpoint of modern applications. It
will be an invaluable resource for researchers and graduate
students interested in the application of analytical
ultracentrifugation in the study of interacting systems, such as
biological macromolecules, multi-protein complexes, polymers, or
nanoparticles.
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