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Theoretical Molecular Biophysics (Hardcover, 2nd ed. 2017)
Loot Price: R4,120
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Theoretical Molecular Biophysics (Hardcover, 2nd ed. 2017)
Series: Biological and Medical Physics, Biomedical Engineering
Expected to ship within 12 - 17 working days
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This book gives an introduction to molecular biophysics. It starts
from material properties at equilibrium related to polymers,
dielectrics and membranes. Electronic spectra are developed for the
understanding of elementary dynamic processes in photosynthesis
including proton transfer and dynamics of molecular motors. Since
the molecular structures of functional groups of bio-systems were
resolved, it has become feasible to develop a theory based on the
quantum theory and statistical physics with emphasis on the
specifics of the high complexity of bio-systems. This introduction
to molecular aspects of the field focuses on solvable models.
Elementary biological processes provide as special challenge the
presence of partial disorder in the structure which does not
destroy the basic reproducibility of the processes. Apparently the
elementary molecular processes are organized in a way to optimize
the efficiency. Learning from nature by means exploring the
relation between structure and function may even help to build
better artificial solar cells. The reader is exposed to basic
concepts in modern biophysics, such as entropic forces, phase
separation, potential of mean force, electron and proton transfer,
heterogeneous reactions, coherent and incoherent energy transfer as
well as molecular motors. Basic knowledge in classical and Quantum
mechanics, electrostatics and statistical physics is desirable.
Simplified models are presented which can be solved in limited
cases analytically from the guiding lines to generate the basis for
a fundamental understanding of the more complex biophysical
systems. Chapters close with challenging problems whose solutions
are provided at the end of the book to complete the pedagogical
treatment in the book. To the second edition several new chapters
were added. The medium polarization is treated self-consistently
using basic elements of polaron theory and more advanced nonlinear
Schroedinger equations to describe the dynamics of solvation. Ion
transport through a membrane was extended by the discussion of
cooperative effects. Intramolecular transitions are now discussed
in the new edition in much more detail, including also
radiationless transitions. Very recent developments in spectroscopy
are included, especially two-dimensional and hole-burning
spectroscopy. The discussion of charge transfer processes was
extended by including recent results of hole transfer in DNA in
connection with the super-exchange mechanism. The chapter on
molecular motors was rewritten to include the most recent
developments of new models. The book is a useful text for students
and researchers wanting to go through the mathematical derivations
in the theories presented. This book attracts a group of applied
mathematically oriented students and scholars to the exciting field
of molecular biophysics.
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