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Asthma: Pathophysiology, Herbal and Modern Therapeutic Interventions (Paperback, 1st ed. 2021)
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Asthma: Pathophysiology, Herbal and Modern Therapeutic Interventions (Paperback, 1st ed. 2021)
Series: SpringerBriefs in Immunology
Expected to ship within 10 - 15 working days
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Asthma is a chronic airway disease affecting over 300 million
people worldwide with an expected increase of an additional 100
million by 2025. Past decade has observed a notable increase in
asthma prevalence on both national and global levels with highest
rates observed in western countries (about 30%). Over the past 40
years, a drastic increase in global prevalence, morbidity,
mortality, and economic burden have been observed due to asthma
especially in children. The rising numbers of hospital admissions
for asthma, especially young children, reflect an increase in
severe asthma, poverty and lack of proper disease management.
Worldwide, approximately 180,000 deaths annually are caused due to
this condition. The financial burden on a single asthma patient per
year in different western countries ranges from US$300-1,300.
Asthma is an intricate respiratory disorder with differences in its
severity, natural history and hence treatment response. These
differences in intensities of various presentations such as
bronchial hyper-responsiveness, airway inflammation, mucus
production, airflow obstruction make asthma a heterogeneous
disease. The mainstay of current therapies for asthma includes
inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene
modifiers and 2-adrenoceptor agonists. Some of the currently
available drugs are efficient in one or more aspects. However the
associated side effects or heterogeneity of the disease limit their
usefulness and efficacy, thereby putting a demand on development of
new drugs and therapies. On the other hand, asthma has also been
treated/managed via herbal medications. These approaches have been
described in Unani, Ayurvedic or Chinese system of medicine since
antiquity. In fact, several anti-asthmatic drugs were developed
from herbs commonly utilized in the non-Western system of medicine.
This book focuses on the pathophysiology of asthma, its medication
(both herbal and modern), limitations and their future prospects.
General
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