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Protein Stability and Folding - A Collection of Thermodynamic Data (Paperback, Softcover reprint of the original 1st ed. 1998)
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Protein Stability and Folding - A Collection of Thermodynamic Data (Paperback, Softcover reprint of the original 1st ed. 1998)
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Protein folding remains one of the most exclusive problems of
modern biochemistry. Structure analysis has given access to the
wealth of the molecular architecture of pro teins. As architecture
needs static calculations, protein structure is always related to
thermodynamic factors that govern folding and stability of a
particular folded protein over the non-organized polypeptide chain.
During the past decades a huge amount of thermodynamic data related
to protein folding and stability has been accumulated. The data are
certainly of importance in dechiffring the protein folding problem.
At the same time, the data can guide the con struction of modified
and newly synthesized proteins with properties optimized for
particular application. The intention of this book is a generation
of a data collection which makes the vast amount of present data
accessible for multidisciplinary research where chemistry, phy
sics, biology, and medicine are involved and also pharmaceutical
and food research and technology. It took several years to compile
all the data and the author wishes to thank everyone who provided
data, ideas or even unpublished results. The author is, in
particular, indebted to Prof. Wadso (Lund, Sweden) and IUPAC's
Steering Committee on Bio physical Chemistry. Furthermore, support
by the Deutsche Forschungsgemeinschafi (INK 16 AI-I) is
acknowledged."
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