More than four decades have passed since surface-enhanced Raman scattering (SERS) was discovered. In today's world SERS has been established as a plasmon-based spectroscopy with ultra-high sensitivity and versatility at the forefront of the developments in plasmonics. SERS has been developing with the advances in nanoscience and nanotechnology. The "SERS world" has grown up markedly for the last 20 years or so, and recently the wider concept of, plasmon-enhanced spectroscopy was born. Plasmon-enhanced spectroscopy contains not only SERS but also tip-enhanced Raman scattering (TERS), surface-enhanced infrared absorption (SEIRA), surface-enhanced fluorescence (SEF), and more. Through these novel spectroscopies various amazing properties of plasmons have become known, providing new exciting research fields. One of the main purposes of the book is to convey the enthusiastic discussion on plasmon-enhanced spectroscopy at the symposium to the scientific community. This book reports leading-edge advances in the theory of plasmonic enhancement and application of plasmon-enhanced spectroscopy to biology, chemistry, physics, materials science, and medicine. Many books have been published about SERS, but this may be the first time that a book on a wide area of plasmon-enhanced spectroscopy has ever been published. The book consists of two volumes; the second volume discusses TERS, SEIRA, and other topics related to plasmon-enhanced spectroscopy.

In todays’ world with its widespread usage of personal-care products, pharmaceuticals, surfactants, flame retardants, plasticizers, various industrial additives, metals and metalloids, pesticides, and pesticide metabolites, environmental contaminants are an increasing source of pollution with a severe effect on the ecological system. Industries that produce these contaminants must find answers to remediate this. Nanomaterials in Environmental Analysis contributes to solving this problem by providing researchers in industry and academia with promising applications of nanoparticles in detection techniques and in removal of chemical species from the environment. Each chapter covers an aspect of using nanoparticles in detecting, measuring and remediating toxic chemical species in the environment.

Comprehensive Analytical Chemistry Volume 101, "Smartphones for chemical analysis: From proof-of-concept to analytical applications" highlights the emergence of smartphones as analytical detectors in the chemical analysis field. The volume covers a wide range of topics starting from the contribution of smartphones towards ubiquitous testing. The challenges related to their coupling with various analytical methods, such as, colorimetry or electrochemistry are identified and discussed to enhance trust towards this newly emerge technology. Case studies with applications of smartphone-based methods in various analytical fields, e.g., food or microplastics analysis are also comprehensively presented.

Fundamentals of Sensor Technology: Principles and Novel Designs presents an important reference on the materials, platforms, characterization and fabrication methods used in the development of chemical sensor technologies. Sections provide the historical context of sensor technology development, review principles for the design of sensing devices and circuits, delve into the most common chemical and biological sensor types, cover unique properties and performance requirements, discuss fabrication techniques, including defining critical parameters, modeling and simulation strategies, and present important materials categories used in sensing applications, such as nanomaterials, quantum dots, magnetic materials, and more. This book is appropriate for the interdisciplinary community of researchers and practitioners interested in the development of sensor technologies, including materials scientists and engineers, analytical chemists and other related disciplines.

Nanotechnology-Based E-Noses: Fundamentals and Emerging Applications reviews advances in nanomaterials and their modification for use in e-sensors. Theoretical understanding of nanomaterials and technologies for improving sensors with better detection limits are covered, as are the most relevant nanomaterials, their synthesis strategies and the relationship between properties and device performance. Current state-of-the-art progress in nanotechnology device fabrication, along with directions for future applications and challenges are also discussed. This book will be an ideal resource for materials scientists, engineers, chemists, researchers in academia and R&D in industry. Recently, "e-noses" or "electronic sensors" are emerging as advanced technologies for the fast detection of chemicals, gases and explosives. The concept behind the "e-nose" is similar to the capability of humans and dogs in detecting materials based on odors. Nanomaterials can be used for e-nose technologies but their properties must be modified to make them effective sensors. The sensing capability and performance these materials depend on several factors such as morphology, dopants, micro-additives, design of sensors, phase and structure of the nanomaterials.

More than four decades have passed since surface-enhanced Raman scattering (SERS) was discovered. In today's world SERS has been established as a plasmon-based spectroscopy with ultra-high sensitivity and versatility at the forefront of the developments in plasmonics. SERS has been developing with the advances in nanoscience and nanotechnology. The "SERS world" has grown up markedly for the last 20 years or so, and recently the wider concept of, plasmon-enhanced spectroscopy was born. Plasmon-enhanced spectroscopy contains not only SERS but also tip-enhanced Raman scattering (TERS), surface-enhanced infrared absorption (SEIRA), surface-enhanced fluorescence (SEF), and more. Through these novel spectroscopies various amazing properties of plasmons have become known, providing new exciting research fields. One of the main purposes of the book is to convey the enthusiastic discussion on plasmon-enhanced spectroscopy at the symposium to the scientific community. This book reports leading-edge advances in the theory of plasmonic enhancement and application of plasmon-enhanced spectroscopy to biology, chemistry, physics, materials science, and medicine. Many books have been published about SERS, but this may be the first time that a book on a wide area of plasmon-enhanced spectroscopy has ever been published. The book consists of two volumes; the first volume contains the introductory review by George Schatz followed by eight chapters, which are mainly concerned with SERS.

Photoelectrochemical Bioanalysis: Fundamentals and Emerging Applications covers the fundamentals from a basic to advanced level, along with the latest accounting of emerging applications. As photoelectrochemical bioanalysis is a rapidly developing area with a wide range developments occurring alongside, it can be difficult for beginners to grasp the understanding of the ever-growing and continuously expanding body of knowledge. Sections detail information on applications in bioanalysis, their working principles, the methodologies of constructions and the approaches adopted with their respective advantages and disadvantages. This book will assist researchers in understanding the latest advances in the materials and engineering aspects of PCE bioanalysis. It also provides researchers with an overview of modern strategies applied for the performance enhancement of PCE materials as well as the modifications suggested to improve the potential of PCE bioanalytical techniques. Last but not least, it will assist researchers in finding gaps and potential opportunities in the field to impart novelty in their research

ICP-MS and Trace Element Analysis as Tools for Better Understanding Medical Conditions, Volume 97 discusses trace elements and how they play an important role in biological functions and metabolism in the human body. Chapters cover Biomedical analysis by ICP-MS: A focus on single cell, Advanced statistical tools and machine learning applied to trace element analysis associated with medical conditions, ICP-MS as a tool to understand trace element homeostasis in neurological disorders, High-precision isotopic analysis of essential mineral elements - possibilities for medical diagnosis and prognosis, Exploring ICP-MS as a versatile technique: From imaging to chemical speciation, and more.

The volume has as primary focus multidimensional gas chromatography (heart-cutting systems, comprehensive 2D-GC systems and hybrid solutions) and its characteristic features for in depth investigation of complex fractions of odor-active volatiles. Contributions, from outstanding researchers in the field from Academia and industry, cover fundamentals aspects on the physiology of olfaction, the strategies to identify key-odorants from the bulk of detectable volatiles (sensomics), the principles of operation of multidimensional analytical platforms (i.e., comprehensive two-dimensional gas chromatography - GCxGC; heart-cut 2D-GC, hybrid systems), and the fundamental role of mass spectrometry in providing reliable and informative data. Insights on new systems design and configurations are also provided, including sample preparation and data processing strategies, as important steps of the whole analytical process. Real-world examples cover food volatiles, complex aroma mixtures, odors emitted from industrial plants, volatiles of interest in forensic and medical applications.

Photoacoustic and Photothermal Spectroscopy: Principles and Applications introduces the basic principles, instrumentation and major developments in the many applications of Photoacoustic and Photothermal Spectroscopy over the last three decades. The book explains the processes of sound generation by periodic optical excitation and ultrasonic generation by pulsed laser excitation and describes the workings of photoacoustic cells equipped with microphones and piezoelectric transducers. Photoacoustic imaging (PAI) is one of the fastest-growing imaging modalities of recent times. It combines the advantages of ultrasound and optical imaging techniques. These non-invasive and non-destructive techniques offer many benefits to users by enabling spectroscopy of opaque and inhomogeneous materials, (solid, liquid, powder, gel, gases) without any sample preparation, and more.

Colorimetry is concerned with the measurement of, and discrimination between, colours. These are important topics in a wide range of the physical sciences, life sciences, and computing and engineering. Examples of specific areas where the techniques of colorimetry are used are: manufacturers of paints, textiles, plastics and cosmetics (and quality controllers in these industries), those interested in the effect of light in human environments (for example, in terms of its direct effects on the eye, laser safety and design of eye protection and ergonomics of hospital lighting), psychology, physiology and those involved in the technical aspects of photography. The book presents the physiological background behind how colour is perceived and discusses sources of visible radiation, before going on to describe in detail colorimetric techniques for measuring and discriminating between colours. Applications of these techniques are discussed and relevant mathematical data is provided. The book gives a comprehensive account of the physiological aspects of colour, the development of photometry and colorimetry, and applications of colorimetry in a single volume.

Counterterrorist Detection Techniques of Explosives, Second Edition covers the most current techniques available for explosive detection. This completely revised volume describes the most updated research findings that will be used in the next generation of explosives detection technologies. New editors Drs. Avi Cagan and Jimmie Oxley have assembled in one volume a series of detection technologies written by an expert group of scientists. The book helps researchers to compare the advantages and disadvantages of all available methods in detecting explosives and, in effect, allows them to choose the correct instrumental screening technology according to the nature of the sample.

Surface Plasmon Resonance in Bioanalysis, Volume 95 in the Comprehensive Analytical Chemistry series, contains a wide range of topics on the applications and new advances of surface plasmon resonance (SPR) in bioanalysis, including Surface plasmon resonance microscopy for single-cell based drug screening, Phase-Sensitive Surface Plasmon Resonance Sensors for Highly Sensitive Bioanalysis, SPR coupled to ambient mass spectrometry, Surface Plasmon Resonance Microscopy for activity detection and imaging of single cells, SPR for water pollutant detection and biofouling control, SPR imaging for cellular analysis and detection, Progress in detection of surface palsmon resonance for biorefinery technology, and more. Additional chapters cover Long-range surface plasmon resonance and its biological sensing applications and Critical issues in clinical and biomedical applications of Surface Plasmon Resonance sensing.

Metal Chalcogenide Biosensors: Fundamentals and Applications provides an overview of advances in materials development of chalcogenides for use in biosensing and sensing applications. The metal chalcogenides discussed include highly reactive metals, noble metals and transition metals. Particular attention is given to the morphology, porosity, structure and fabrication of materials for biosensing applications. The connection between the chalcogenides' physical and chemical properties and device performance is explored. Key parameters for biosensor devices are investigated such as thermodynamics, kinetics, selectivity, sensitivity, efficiency and durability to aid in materials selection. Finally, a range of biosensor devices are addressed including gas biosensors, chemical biosensors, environment biosensors and biological molecule sensors. This book is suitable for those in the fields of materials science and engineering, chemistry and physics.

Analytical Nebulizers: Fundamentals and Applications presents the fundamentals of analytical nebulizers, including types, aerosol generation, characterization, and design information of various classes of nebulizers such as nanonebulizers, multinebulizers, electrosprays, and ultrasonic nebulizers. The continuous development of new analytical techniques and materials make these technological approaches very interesting for those working in the industrial sector. In addition, although the book mainly focuses on the application of analytical nebulizers in analytical sciences, specifically in sample preparation, it is also useful to those in other disciplines (e.g. organic chemistry, catalysis, sensors, nanotechnology, biomedicine and nanomedicine, and environmental chemistry) where these nebulizers have great potential. Non-conventional applications of nebulizers such as aerosol-assisted synthesis nanoparticles and ultrasonic nebulization extraction are also presented.

Chemometrics in Spectroscopy, Revised Second Edition provides the reader with the methodology crucial to apply chemometrics to real world data. The book allows scientists using spectroscopic instruments to find explanations and solutions to their problems when they are confronted with unexpected and unexplained results. Unlike other books on these topics, it explains the root causes of the phenomena that lead to these results. While books on NIR spectroscopy sometimes cover basic chemometrics, they do not mention many of the advanced topics this book discusses. This revised second edition has been expanded with 50% more content on advances in the field that have occurred in the last 10 years, including calibration transfer, units of measure in spectroscopy, principal components, clinical data reporting, classical least squares, regression models, spectral transfer, and more.

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques.

Big Data Analytics in Chemoinformatics and Bioinformatics: With Applications to Computer-Aided Drug Design, Cancer Biology, Emerging Pathogens and Computational Toxicology provides an up-to-date presentation of big data analytics methods and their applications in diverse fields. The proper management of big data for decision-making in scientific and social issues is of paramount importance. This book gives researchers the tools they need to solve big data problems in these fields. It begins with a section on general topics that all readers will find useful and continues with specific sections covering a range of interdisciplinary applications. Here, an international team of leading experts review their respective fields and present their latest research findings, with case studies used throughout to analyze and present key information.

Airborne Microplastics: Analysis, Fate and Human Health Effects, Volume 105 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Thermal Analysis: From Introductory Fundamentals to Advanced Applications presents an easy-to-understand introduction to Thermal Analysis (TA) principles alongside in-depth coverage of the wide variety of techniques currently in use across several industries. It covers differential scanning calorimetry (DSC), temperature modulated DSC (TMDSC), differential thermal analysis (DTA), thermogravimetry (TG) or thermogravimetric analysis (TGA), thermomechanical analysis (TMA), differential photo-calorimetry (DPC), dynamic mechanical analysis (DMA), thermodilatometry (TD), dielectric thermal analysis (DEA), thermally-stimulated current (TSC), emanation thermal analysis (ETA), thermoluminescence (TL), fast scanning calorimetry (FSC), and microcalorimetry. Chapters define the various TA techniques, report the Temperature-Modulated DSC (TMDSC) method and its applications, especially its use for studying the thermodynamic properties of polymers and pharmaceuticals, focus on the potential of TA in materials science with applications in chemistry and engineering, demonstrate, in detail, the various applications of TA in food, electronic industries, solid-state reactions, chemistry of polymers and large directing agents, kinetic studies, demonstrate the crystal structure and phase changes occurring upon heating by TA, and the potential of TA in recycling and waste management.

Carbon Dots in Analytical Chemistry: Detection and Imaging explores recent progress in the field of carbon dots synthesis and properties and their integration with various miniaturized analytical devices for the detection of chemical species and imaging of cells. This book is dedicated to exploring the potential applications of carbon dots in analytical chemistry for clinical microbiology, pharmaceutical analysis and environmental analysis. Sections cover synthetic approaches and properties, sample preparation, analytical techniques for the detection of chemical species, imaging of molecules and cells, and analytical tools for biomedical and food analysis. The will be a valuable book for analytical and materials scientists, physical and chemical scientists, and engineers investigating the use of carbon nanomaterials in their analytical procedures.

Instrumental Thin-Layer Chromatography, Second Edition offers a comprehensive source of authoritative information on all aspects of instrumental thin-layer chromatography. The use of short, topic-focused chapters facilitates identifying information of immediate interest for familiar or emerging uses of thin-layer chromatography. The book gives those working in both academia and industry the opportunity to learn, refresh, or deepen their understanding of fundamental and instrumental aspects of thin-layer chromatography, as well as the tools to interpret and manage chromatographic data. The book serves as a practical consolidated guide to the selection of separation conditions and the use of auxiliary techniques. This fully updated new edition restores the contemporary character of the book for those involved in advancing the technology, analyzing data produced, or applying the technique to new application areas. Some chapters have been consolidated to make room for topics not covered in the first edition, reflecting general changes in the field of thin-layer chromatography, especially in effects-directed detection, convenient interfaces for advanced spectroscopic detection, and greater automation possibilities. This book is a valuable reference for anyone who needs to acquire fundamental and practical information to facilitate progress in research and management functions utilizing information acquired by thin-layer chromatography.

Analysis and Characterisation of Metal-Based Nanomaterials, Volume 93 in the Comprehensive Analytical Chemistry series, introduces recent developments in analytical methodologies for detection, characterization and quantification of metal-based nanomaterials and their applications to a variety of complex environmental, biological and food samples as well as different consumer products. Single-particle inductively coupled plasma mass spectrometry is highlighted as a powerful analytical tool for number-based concentration and size distribution, also from the metrological viewpoint. An emerging approach for the measurement of multi-metal nanoparticles by single-particle inductively coupled plasma time-of-flight mass spectrometry is discussed. Imaging of metal-based nanoparticles by hyphenated inductively coupled plasma-based techniques is also introduced. The potential of different liquid chromatography and field flow fractionation separation techniques hyphenated to inductively coupled plasma mass spectrometry is emphasized as a powerful tool in particular for complex matrices and small particles sizes. The use of different microscopic techniques for the characterization of metal-based nanoparticles and characterization of metal-based nanoparticles as contrast agents for magnetic resonance imaging are presented. Moreover, occurrence, behaviour and fate of inorganic nanoparticles in the environment is overviewed. Finally, the need for quality control standards and reference nano-materials is emphasized throughout.