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Books > Science & Mathematics > Chemistry > Analytical chemistry

The Handbook of Metabolic Phenotyping (Paperback): John C. Lindon, Jeremy K. Nicholson, Elaine Holmes The Handbook of Metabolic Phenotyping (Paperback)
John C. Lindon, Jeremy K. Nicholson, Elaine Holmes
R5,115 Discovery Miles 51 150 Ships in 12 - 17 working days

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics.

Data Analysis for Omic Sciences: Methods and Applications, Volume 82 (Hardcover): Joaquim Jaumot, Carmen Bedia, Roma Tauler Data Analysis for Omic Sciences: Methods and Applications, Volume 82 (Hardcover)
Joaquim Jaumot, Carmen Bedia, Roma Tauler
R6,615 Discovery Miles 66 150 Ships in 12 - 17 working days

Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more.

Solid Phase Microextraction - A PRACTICAL GUIDE (Hardcover): Sue Ann Wercinski Solid Phase Microextraction - A PRACTICAL GUIDE (Hardcover)
Sue Ann Wercinski
R5,800 R4,801 Discovery Miles 48 010 Save R999 (17%) Ships in 12 - 17 working days

An explanation of proven methods of chemical analysis, focusing on the myriad applications of solid phase microextraction (SPME) to laboratories performing high-sample throughput, quick sample turnaround time, low detection levels, and dirty sample matrices. It supplies commentary on developments in SPME technology from its inventor, Janusz Pawliszyn.

Practical Supercritical Fluid Chromatography and Extraction (Hardcover): Thomas Caudell Practical Supercritical Fluid Chromatography and Extraction (Hardcover)
Thomas Caudell
R6,295 Discovery Miles 62 950 Ships in 12 - 17 working days

This book explores the fundamental and practical aspects of supercritical fluid chromatography (SFC) and extraction. It discusses packed columns in SFC; detection in SFC; supercritical fluid chromatography/mass spectroscopy; and evaporative light scattering detection in SFC.

Canines - The Original Biosensors (Hardcover): Lauryn E. DeGreeff, Craig A. Schultz Canines - The Original Biosensors (Hardcover)
Lauryn E. DeGreeff, Craig A. Schultz
R4,423 Discovery Miles 44 230 Ships in 9 - 15 working days

Detection canines have been utilized throughout the world for over a century, and while numerous attempts have been made to replicate the canine's ability to detect substances by mechanical means, none has been as successful. The olfactory system is a highly intricate and sophisticated design for chemical sensing, and the olfactory capacity of many animals, including canines, is considered unmatched by machine due to not only their great sensitivity and superior selectivity but also their trainability and mobility. These unique features have led to the use of such animals as "whole-animal" biosensors. Amplifying the benefits and diminishing the limitations of detection canines' interdisciplinary research is crucial to understanding canine olfaction and detection and enhancing this powerful and complex detector. The past 50 years have produced vast advancements in animal behavior/training technology to develop canines into more proficient and reliable sensors, while scientific research has provided tremendous support to help practitioners better understand how to utilize this powerful sensor. This book assembles a diverse group of authors with expertise in a variety of fields relating to detection canines and the chemical sensing industry, including both research and operational perspectives on detection canines. It illustrates how science enhances our understanding of how canines are employed for solving some of the world's leading detection challenges.

Annual Reports on NMR Spectroscopy, Volume 95 (Hardcover): Graham A. Webb Annual Reports on NMR Spectroscopy, Volume 95 (Hardcover)
Graham A. Webb
R5,656 Discovery Miles 56 560 Ships in 12 - 17 working days

Annual Reports on NMR Spectroscopy, Volume 95, provides an in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications. In recent years, no other technique has gained as much significance. It is used in all branches of science in which precise structural determination is required, and in which the nature of interactions and reactions in solution is being studied. This book has established itself as a premier resource for both specialists and non-specialists who are looking to become familiar with new techniques and applications pertaining to NMR spectroscopy.

Microscopy and Microanalysis for Lithium-Ion Batteries (Hardcover): Cai Shen Microscopy and Microanalysis for Lithium-Ion Batteries (Hardcover)
Cai Shen
R4,367 Discovery Miles 43 670 Ships in 12 - 17 working days

The past three decades have witnessed the great success of lithium-ion batteries, especially in the areas of 3C products, electrical vehicles, and smart grid applications. However, further optimization of the energy/power density, coulombic efficiency, cycle life, charge speed, and environmental adaptability are still needed. To address these issues, a thorough understanding of the reaction inside a battery or dynamic evolution of each component is required. Microscopy and Microanalysis for Lithium-Ion Batteries discusses advanced analytical techniques that offer the capability of resolving the structure and chemistry at an atomic resolution to further drive lithium-ion battery research and development. * Provides comprehensive techniques that probe the fundamentals of Li-ion batteries. * Covers the basic principles of the techniques involved as well as its application in battery research. * Describes details of experimental set-ups and procedure for successful experiments. This reference is aimed at researchers, engineers, and scientists studying lithium-ion batteries including chemical, materials, and electrical engineers, as well as chemists and physicists.

Advanced Materials Characterization - Basic Principles, Novel Applications, and Future Directions (Hardcover): Ch Sateesh... Advanced Materials Characterization - Basic Principles, Novel Applications, and Future Directions (Hardcover)
Ch Sateesh Kumar, M Muralidhar Singh, Ram Krishna
R3,157 Discovery Miles 31 570 Ships in 12 - 17 working days

Covers material characterization techniques and the development of advanced characterization technology Includes multiple length scale characterization approaches for a large variety of materials, from nano- to micron-scale, as well as their constraints Discusses advanced material characterization technology in the microstructural and property characterization fields Reviews both practical and theoretical explanations of approaches for characterizing microstructure and properties Offers fundamentals, basic instrumentation details, experimental approaches, analyses, and applications with case studies

Structure-Based Drug Design (Hardcover): Pandi Veerapandian Structure-Based Drug Design (Hardcover)
Pandi Veerapandian
R5,446 Discovery Miles 54 460 Ships in 12 - 17 working days

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

Chromatographic Analysis of Pharmaceuticals - Second Edition, Revised and Expanded (Hardcover, 2nd edition): John A. Adamovics Chromatographic Analysis of Pharmaceuticals - Second Edition, Revised and Expanded (Hardcover, 2nd edition)
John A. Adamovics
R8,653 Discovery Miles 86 530 Ships in 12 - 17 working days

Updated and revised throughout. Second Edition explores the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations--such as tablets, ointments, and injectables. Contains a 148-page table listing the chromatographic data of over 1300 drugs and related substances--including sample matrix analyzed, sample handling procedures, column packings, mobile phase, mode of detection, and more.

Handbook of Thermal Analysis and Calorimetry, Volume 6 - Recent Advances, Techniques and Applications (Paperback, 2nd edition):... Handbook of Thermal Analysis and Calorimetry, Volume 6 - Recent Advances, Techniques and Applications (Paperback, 2nd edition)
Sergey Vyazovkin, Nobuyoshi Koga, Christoph Schick
R8,301 R7,449 Discovery Miles 74 490 Save R852 (10%) Ships in 12 - 17 working days

Handbook of Thermal Analysis and Calorimetry: Recent Advances, Techniques and Applications, Volume Six, Second Edition, presents the latest in a series that has been well received by the thermal analysis and calorimetry community. This volume covers recent advances in techniques and applications that complement the earlier volumes. There has been tremendous progress in the field in recent years, and this book puts together the most high-impact topics selected for their popularity by new editors Sergey Vyazovkin, Nobuyoshi Koga and Christoph Schick-all editors of Thermochimica Acta. Among the important new techniques covered are biomass conversion; sustainable polymers; polymer nanocompsoties; nonmetallic glasses; phase change materials; propellants and explosives; applications to pharmaceuticals; processes in ceramics, metals, and alloys; ionic liquids; fast-scanning calorimetry, and more.

Analytical Chemistry of PCBs (Hardcover, 2nd edition): Mitchell D. Erickson Analytical Chemistry of PCBs (Hardcover, 2nd edition)
Mitchell D. Erickson
R7,227 Discovery Miles 72 270 Ships in 12 - 17 working days

This updated and expanded Second Edition of Dr. Erickson's Analytical Chemistry of PCBs appears a decade after the first and is completely revised and updated. The changes from the First Edition reflect the significant growth in the area and a growing appreciation of the importance of PCB analysis to our culture. This book is a comprehensive review of the analytical chemistry of PCBs. It is part history, part annotated bibliography, part comparison, and part guidance. Featuring a new chapter on analyst/customer interactions and several new appendices, the Second Edition is an invaluable resource for both chemists with no experience in PCB analysis and seasoned PCB researchers.
All topics have been more thoroughly treated and updated in this new edition to reflect advances made in the last decade, especially:

Practical Thin-Layer Chromatography - A Multidisciplinary Approach (Paperback): Bernard Fried Practical Thin-Layer Chromatography - A Multidisciplinary Approach (Paperback)
Bernard Fried
R4,074 R3,481 Discovery Miles 34 810 Save R593 (15%) Ships in 12 - 17 working days

Practical Thin-Layer Chromatography provides thorough coverage of the principles, practices, and applications of thin-layer chromatography (TLC) for important sample and compound types. This information is directed specifically at workers in the most active scientific fields.

Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Applications, Volume... Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Applications, Volume 79 (Hardcover)
Achille Cappiello, Pierangela Palma
R6,565 Discovery Miles 65 650 Ships in 12 - 17 working days

Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Application, Volume 79, highlights the most recent LC-MS evolutions through a series of contributions by world renowned scientists that will lead the readers through the most recent innovations in the field and their possible applications. Many authoritative books on LC-MS are already present in market, describing in detail the different interfaces and their principles of operation. This book focuses more on new trends, starting with the innovations of each technique, to the most progressive challenges of LC-MS.

Validation Compliance Annual - 1995 (Hardcover): International Validation Forum Validation Compliance Annual - 1995 (Hardcover)
International Validation Forum
R10,488 Discovery Miles 104 880 Ships in 12 - 17 working days

This indispensable guide offers detailed coverage of the regulations, requirements, and techniques for the validation of processes and systems used in regulated international industries - addressing all significant requirements for pharmaceutical, medical device, and biologic companies as well as environmental laboratories. Elucidating up-to-the-minute industry changes and international concerns, Validation Compliance Annual 1995 examines Good Manufacturing Practices (GMPs), Good Clinical Practices (GCPs), Good Laboratory Practices (GLPs), and Good Automated laboratory Practices (GALPs)... provides unabridged texts of U.S. and European Union regulatory requirements as well as summaries of the validation requirements of other nations... furnishes complete guidelines and tools for system validation... supplies an in-depth look at problems related to inadequate system validation, including actual regulatory citations for noncompliance... explains the rationale behind regulatory compliance policies and inspectional practices... assesses the future of regulatory and industry trends... and more. Containing key bibliographic citations and a thorough glossary of validation terms, Validation Compliance Annual 1995 is an incomparable day-to-day workbook for analytical, pharmaceutical, food, and environmental chemists; instrumentation specialists; industrial, bio-process, chemical, and pharmaceutical engineers; quality and reliability managers and directors; laboratory managers and technicians; computer scientists; and upper-level undergraduate and graduate students in these disciplines.

Practical Guide to Infrared Microspectroscopy (Hardcover): Howard J. Humecki Practical Guide to Infrared Microspectroscopy (Hardcover)
Howard J. Humecki
R8,037 Discovery Miles 80 370 Ships in 12 - 17 working days

This work represents a sound introduction to the fundamental principles of infrared microspectroscopy (IMS). It describes how IMS is used to solve specific microanalytical problems in a variety of disciplines, including forensic analysis, art conservation, and geological, pharmaceutical and electronics research. The book discusses when and how to use special techniques such as line scanning, 3-dimensional imaging and attenuated total reflection and grazing-angle spectroscopy.

High-Resolution Mass Spectroscopy for Phytochemical Analysis - State-of-the-Art Applications and Techniques (Hardcover):... High-Resolution Mass Spectroscopy for Phytochemical Analysis - State-of-the-Art Applications and Techniques (Hardcover)
Sreeraj Gopi, Augustine Amalraj, Shintu Jude
R3,676 Discovery Miles 36 760 Ships in 9 - 15 working days

Covers the fundamental instrumentation and techniques Discusses HRMS-based phytochemical research details Focuses strictly on the phytochemical considerations

Bioactive Lipid Mediators - Current Reviews and Protocols (Hardcover, 1st ed. 2015): Takehiko Yokomizo, Makoto Murakami Bioactive Lipid Mediators - Current Reviews and Protocols (Hardcover, 1st ed. 2015)
Takehiko Yokomizo, Makoto Murakami
R5,599 Discovery Miles 55 990 Ships in 12 - 17 working days

This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry. Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediators in Drosophila and Zebrafish (Part II), the relationships between lipid mediators and various diseases (Part III), and detailed procedures of extraction, preparation, and quantification of lipid mediators (Part IV). Research on lipid mediators initially started with analysis of the action of aspirin, and subsequent biochemical experiments identified many enzymes and receptors responsible for the biosynthesis and signal transduction of individual lipid mediators. Through the phenotypic analyses of transgenic and knockout mice, it has been shown that the dysregulation of some lipid mediators causes inflammatory, immune, or oncogenic disorders. Lipid mediators have attracted increased attention because their structures are conserved among different species, and their biosynthetic and signaling pathways have been deciphered at the molecular level. Many drugs that target lipid mediators are already being used in hospitals, and this book suggests further possibilities for development of a wide variety of such drugs. Very recently, highly sensitive mass spectrometry has begun to be used to identify novel lipid mediators that are present only in trace amounts in tissues but with robust biological activity. Written by international experts, this book provides readers a comprehensive view of lipid mediators and related topics and helps in the process of determining research targets for the near future.

Nanoscopy and Nanospectroscopy (Hardcover): Sandip Dhara, Deep Jariwala, Soumen Das Nanoscopy and Nanospectroscopy (Hardcover)
Sandip Dhara, Deep Jariwala, Soumen Das
R3,778 Discovery Miles 37 780 Ships in 12 - 17 working days

Covers the broad area of nano-optical spectroscopy from the perspective of putting the concepts and innovations in the field to use Discusses entire spectra of near-field optics and spectroscopy using light Includes dielectric nanophotonics and optical confinement Studies acoustic phonon confinement for analysis of chemical, biological, and other materials Explores gas/chemical sensing using surface plasmon resonance (SPR) in the Kretschmann configuration

Gas Chromatography In Forensic Science (Hardcover, 2 New Edition): Ian Tebbett Gas Chromatography In Forensic Science (Hardcover, 2 New Edition)
Ian Tebbett
R6,259 Discovery Miles 62 590 Ships in 12 - 17 working days

Written by a team of internationally renowned experts, this book focuses on the application of gas chromatography to various aspects of forensic chemistry. The authors introduce the basic theory of chromatographic separations before discussing specific forensic issues such as drug analysis and fires and explosives. Problems faced by forensic scientists, including degraded samples and small sample size, are also addressed.

Ultrashort Pulse Lasers and Ultrafast Phenomena (Hardcover): Takayoshi Kobayashi Ultrashort Pulse Lasers and Ultrafast Phenomena (Hardcover)
Takayoshi Kobayashi
R4,933 Discovery Miles 49 330 Ships in 12 - 17 working days

This book describes the basic physical principles of techniques to generate and ultrashort pulse lasers and applications to ultrafast spectroscopy of various materials covering chemical molecular compounds, solid-state materials, exotic novel materials including topological materials, biological molecules and bio- and synthetic polymers. It introduces non-linear optics which provides the basics of generation and measurement of pulses and application examples of ultrafast spectroscopy to solid state physics. Also it provide not only material properties but also material processing procedures. The book describes also details of the world shortest visible laser and DUV lasers developed by the author's group. It is composed of the following 12 Sections: The special features of this book is that it is written by a single author with a few collaborators in a systematic way. Hence it provides a comprehensive and systematic description of the research field of ultrashort pulse lasers and ultrafast spectroscopy. Generation of ultrashort pulses in deep ultraviolet to near infrared Generation of ultrashort pulses in terahertz Carrier envelope phase (CEP) Simple NLO processes with a few colors Multi-color involved NLO processes Multi-color ultrashort pulse generation NLO materials NLO processes in time-resolved spectroscopy Low dimension materials Conductors and superconductors Chemical reactions and material processing Photobiological reactions

Successful Management of the Analytical Laboratory (Hardcover): Oscar I. Milner Successful Management of the Analytical Laboratory (Hardcover)
Oscar I. Milner
R6,109 Discovery Miles 61 090 Ships in 12 - 17 working days

Successful Management of the Analytical Laboratory provides a comprehensive discussion of the problems that face analytical laboratory managers and presents proven techniques for improving the operation and performance of analytical labs. A wide range of topics are covered, including functions of various laboratory types (including a discussion of legal proceedings that involve defending laboratory data), staffing and organization, motivation, management and development of personnel, personal relations and communication, sample handling, workload optimization, equipment selection and justification, budgeting and cost control (including methods for calculating the dollar return on investments in capital equipment), and information management systems.
The book emphasizes measures that managers can take to ensure quality performance in both the laboratory and its personnel while maintaining the overall cost effectiveness of the operation. The author uses case histories from his experience to illustrate the application of the management principles presented in this excellent book for new and experienced lab managers alike.

High-Performance Liquid Chromatography of Peptides and Proteins - Separation, Analysis, and Conformation (Hardcover): Colin T.... High-Performance Liquid Chromatography of Peptides and Proteins - Separation, Analysis, and Conformation (Hardcover)
Colin T. Mant, Robert S. Hodges
R13,991 Discovery Miles 139 910 Ships in 12 - 17 working days

This book consists of a series of 82 precise, easy-to-read articles by internationally renowned scientists and emphasizes the practical approach to HPLC with minimal theory, although the underlying principles for peptide and protein separations are clearly expressed. All of the major modes of microbore, ultrafast and analytical HPLC are discussed, including size-exclusion, ion-exchange, reversed-phase, hydrophobic interaction, and affinity and immunoaffinity chromatography. A section on preparative HPLC, including displacement techniques, is also presented. Problem-solving approaches to the separation of various classes of biologically active peptides and proteins are thoroughly explored, while the importance of peptide standards for monitoring column performance and for optimizing separation conditions is emphasized. Several articles focus on the choice of the correct detection method (electrochemical, UV, fluorescence), as well as the need for a proper knowledge of approaches to column and instrument maintenance and trouble-shooting. A section on predictive approaches deals with both computer simulation of peptide separations and peptide structure. The book also includes complementary techniques to HPLC, as well as other useful applications of HPLC. It enables both novice and experienced chromatographers to realize the full potential of this extremely powerful technique, in the process making an important contribution to scientific literature.

Practical Handbook of Spectroscopy (Hardcover): James W. Robinson Practical Handbook of Spectroscopy (Hardcover)
James W. Robinson
R8,712 Discovery Miles 87 120 Ships in 12 - 17 working days

A convenient single volume handbook featuring the most important topics in spectroscopy

This valuable handbook is based on topics presented in the CRC Handbook of Spectroscopy, Volumes I and II, published in 1974, and Volume III, published in 1981. The information has been condensed (by the original contributor, when possible) so that only the most important information from the original three volumes has been retained and updated. The topics covered include ESCA flame photometry; atomic absorption and emission spectroscopy, including plasma emission; infrared spectroscopy; Raman spectroscopy; ultraviolet absorption spectroscopy; electron spin resonance, X-ray spectroscopy, mass photoelectric absorption coefficients, appearance potential spectroscopy, thermal neutron cross sections and resonance integrals for activation analysis, tables of experimental values of X-ray fluorescence and Coster-Kronig yields for the K-, L-, and M-shells.

Other topics include 14 MeV neutron activation cross sections; wavelength standards in visible, ultraviolet, and near-infrared spectroscopy; electron affinities, wavelength-dependent and electronic system oscillator strengths for free diatomic molecules of astrophysical importance; electron spin resonance applicaton to the study of minerals and glasses; experimental lifetimes, Franck-Condon factors; and vibrational and rotational oscillator strengths. The concise format and wealth of information ensures that no spectroscopist will want to be without the updated and revised Practical Handbook of Spectroscopy.

17 0 NMR Spectroscopy in Organic Chemistry (Hardcover): David W. Boykin 17 0 NMR Spectroscopy in Organic Chemistry (Hardcover)
David W. Boykin
R13,902 Discovery Miles 139 020 Ships in 12 - 17 working days

This book provides a comprehensive review of the application of 17O NMR spectroscopy to organic chemistry. Topics include the theoretical aspects of chemical shift, quadrupolar and J coupling; 17O enrichment; the effect of steric interactions on 17O chemical shifts of functional groups in flexible and rigid systems; the application of 17O NMR spectroscopy to hydrogen bonding investigations; mechanistic problems in organic and bioorganic chemistry; and 17O NMR spectroscopy of oxygen monocoordinated to carbon in alcohols, ethers, and derivatives. Recent results that show correlations between molecular geometry, determined by X-ray studies and estimated by molecular mechanics calculations, and 17O chemical shifts are also covered. 17O Spectroscopy in Organic Chemistry provides important reference information for organic chemists and other scientists interested in 17O NMR spectroscopy as a tool for obtaining new structural and chemical data about organic molecules.

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