Turbulence and magnetic fields are ubiquitous in the Universe. Their importance to astronomy cannot be overestimated. The theoretical advancements in magnetohydrodynamic (MHD) turbulence achieved during the past two decades have significantly influenced many fields of astronomy. This book provides predictive theories of the magnetic field generation by turbulence and the dissipation of MHD turbulence. These fundamental non-linear problems were believed to be tractable only numerically. This book provides complete analytical descriptions in quantitative agreement with existing numerics, as well as theoretical predictions in physical regimes still unreachable by simulations, and explanations of various related observations. It also discusses and promotes the astrophysical applications of MHD turbulence theories, including (i) the particle acceleration and radiation in high-energy phenomena, e.g., Gamma-Ray Bursts, supernova remnants, cosmic rays; (ii) interstellar density fluctuations and the effect on observations, e.g., Faraday rotation, scattering measurements of Galactic and extragalactic radio sources; (iii) density and magnetic field structure in molecular clouds toward star formation. In closing, this book demonstrates the key role of MHD turbulence in connecting diverse astrophysical processes and unraveling long-standing astrophysical problems, as foreseen by Chandrasekhar, a founder of modern astrophysics.

This book gives an overview of recent advances in the fracture mechanics of polymers (experimental and alternative methods), morphology property correlations (homopolymers, copolymers, blends), hybrid methods for polymer testing and polymer diagnostics, and biocompatible materials and medical prostheses, as well as application examples and limits. The investigation of deformation and fracture behaviour using the experimental methods of fracture mechanics has been the subject of intense research during the last decade. In a systematic manner, each chapter of this book gives a review of the particular aspects. This book will be of great value to scientists, engineers and graduates in polymer materials science.

This book deals with an effect in celestial mechanics that has become quite important in exoplanet research. The Lidov-Kozai effect reveals itself in coherent periodic variations (which can be very large) of the inclination and eccentricity of an orbiting body in the presence of an inclined perturber. The effect is known to be important in the motion of many asteroids and planetary satellites. What is more, now it attracts more and more interest in the astronomical and astrophysical community due to its relevance for many exoplanetary systems. Recent years witnessed major advancements in its theory. It would be no exaggeration to say that nowadays the Lidov-Kozai effect becomes one of the most studied astrophysical effects. This book covers the multitude of the Lidov-Kozai effect's modern applications and its theory developments. It will be useful for researchers and students working in astrophysics, celestial mechanics, stellar dynamics, theoretical mechanics, space missions design, depending on the interests of the reader. The book is self-contained. It provides the full detailed coverage of the effect's theory and applications.

Proceedings of a Symposium organized by the Summer Advanced Study Institute, held at Queen's University, Kingston, Ontario, August 3-14, 1970

This book treats essentials from neurophysiology (Hodgkin-Huxley equations, synaptic transmission, prototype networks of neurons) and related mathematical concepts (dimensionality reductions, equilibria, bifurcations, limit cycles and phase plane analysis). This is subsequently applied in a clinical context, focusing on EEG generation, ischaemia, epilepsy and neurostimulation. The book is based on a graduate course taught by clinicians and mathematicians at the Institute of Technical Medicine at the University of Twente. Throughout the text, the author presents examples of neurological disorders in relation to applied mathematics to assist in disclosing various fundamental properties of the clinical reality at hand. Exercises are provided at the end of each chapter; answers are included. Basic knowledge of calculus, linear algebra, differential equations and familiarity with MATLAB or Python is assumed. Also, students should have some understanding of essentials of (clinical) neurophysiology, although most concepts are summarized in the first chapters. The audience includes advanced undergraduate or graduate students in Biomedical Engineering, Technical Medicine and Biology. Applied mathematicians may find pleasure in learning about the neurophysiology and clinic essentials applications. In addition, clinicians with an interest in dynamics of neural networks may find this book useful, too.

1.1. MISSION BACKGROUND The scientific objective of this magnetospheric physics mission was a detailed in vestigation of the Aurora Borealis, or 'Northern Lights'. The fields experiments (electric and magnetic) were constructed by the University of California at Berke ley (UCB), and Los Angeles (UCLA) respectively. The particles instruments were constructed by UCB and the University of New Hampshire in collaboration with Lockheed Palo Alto Research Laboratory. The instrument data processing unit was provided by UCB. The spacecraft bus, telemetry, and launch services were provided by the NASA Goddard Space Flight Center SMEX office. The science principal investigator is Dr C. W. Carlson of UCB, and the program is managed by the SMEX office. The UCB design philosophy emphasizes the demonstration of design margins set by peer review. As a result, each boom system was extensively tested at a prototype level before the flight units were manufactured. Additionally, the design, assembly and testing of each boom mechanism was conducted by a single engineer solely responsible for its success.

In keeping with goal and style of the Handbook in Modern Biophysics series, the proposed book will maintain a chapter structure that contains two parts: concepts and biological application. The book also integrates all the chapters into a smooth, continuous discourse. The first and second chapters establish the mathematical methods and theoretical framework underpinning the different topics in the rest if the book. Other chapters will use the theoretical framework as a basis to discuss optical and NMR approaches. Each chapter will contain innovative didactic elements that facilitate teaching, self-study, and research preparation (key points, summary, exercise, references).

In the last decade, optically functionalized materials have developed rapidly, from bulk matters to structured forms. Now we have a rich variety of attractive advanced materials. They are applied to optical and electrical devices that support the information communication technology in the mid 21-th century. Accordingly, it is quite important to have a broad knowledge of the optical properties of advanced materials for students, scientists and engineers working in optics and related fields. This book is designed to teach fundamental optical properties of such advanced materials effectively. These materials have their own peculiarities which are very interesting in modern optical physics and also for applications because the concepts of optical properties are quite different from those in conventional optical materials. Hence each chapter starts to review the basic concepts of the materials briefly and proceeds to the practical use. The important topics covered in this book include: quantum structures of semiconductors, spintronics, photonic crystals, surface plasmons in metallic nanostructures, photonic metamaterials, liquid crystal materials, organic LED materials and magnet-optics.

The study of surfaces has experienced dramatic growth over the past decade. Now, the editors of the internationally celebrated series Advances in Chemical Physics have brought together in this self-contained, special topic volume contributions from leading researchers in the field treating some of the most crucial aspects of the experimental and theoretical study of surfaces. This work delves into such core issues as:

• Kinetics and dynamics of hydrogen adsorption on silicon surfaces.
• Potential energy surfaces of transition- metal-catalyzed chemical reactions.
• High-resolution helium atom scattering as a proof of surface vibrations.
• Ordering and phase transitions in adsorbed monolayers of diatomic molecules.
• The influence of dimensionality on static and dynamic properties of a system.
• New applications to fields as varied as catalysts and the passage of molecules through membranes.

This valuable resource provides important insights into the current state of knowledge about surface properties. Prigogine and Rice's latest work will stimulate the imagination and motivate the exploration of other aspects of this fascinating subject.

Stellar astrophysics still provides the basic framework for deciphering the imprints left over by the evolving universe on all scales. Advances or shortcomings in the former field have direct consequences in our ability to understand the global properties of the latter.

This volume contains the most recent updates on a variety of topics that, though independent by themselves, are inevitably connected on a cosmological scale. These include comprehensive articles by leaders in fields extending from stellar atmospheres through properties of the stellar component in the Milky Way up to the stellar environment in high redshift galaxies.

The wide coverage of astrophysical themes makes this volume very valuable for researchers and Ph.D. students in astrophysics.

The SOLAR-A spacecraft was launched by the Institute of Space and Astronautical Science, Japan (ISS) in August 1991, and, following and ISAS tradition, was renamed YOHKOH. This mission is dedicated principally to the study of solar flares, especially of high-energy phenomena observed in the X-ray and gamma-ray ranges. With a co-ordinated set of instruments including hard X-ray and soft X-ray imaging telescopes as well as spectrometers with advanced capabilities, it is expected to reveal new aspects of flares and help better understand their physics, supporting international collaborations with ground-based observatories as well as theoretical investigations. An overview of this mission, including the stallite, its scientific instruments, and its operation is given in this book.

Seismic waves - generated both by natural earthquakes and by man-made sources - have produced an enormous amount of information about the Earth's interior. In classical seismology, the Earth is modeled as a sequence of uniform horizontal layers (or spherical shells) having different elastic properties and one determines these properties from travel times and dispersion of seismic waves. The Earth, however, is not made of horizontally uniform layers, and classic seismic methods can take large-scale inhomogeneities into account. Smaller-scale irregularities, on the other hand, require other methods. Observations of continuous wave trains that follow classic direct S waves, known as coda waves, have shown that there are heterogeneities of random size scattered randomly throughout the layers of the classic seismic model. This book focuses on recent developments in the area of seismic wave propagation and scattering through the randomly heterogeneous structure of the Earth, with emphasis on the lithosphere. The presentation combines information from many sources to present a coherent introduction to the theory of scattering in acoustic and elastic materials and includes analyses of observations using the theoretical methods developed. The second edition especially includes new observational facts such as the spatial variation of medium inhomogeneities and the temporal change in scattering characteristics and recent theoretical developments in the envelope synthesis in random media for the last ten years. Mathematics is thoroughly rewritten for improving the readability. Written for advanced undergraduates or beginning graduate students of geophysics or planetary sciences, this book should also be of interest to civil engineers, seismologists, acoustical engineers, and others interested in wave propagation through inhomogeneous elastic media.

The millimetre and submillimetre spectral region (300 to 3000 Ilm or 1000 to 100 GHz) was until recently one of the few spectral regimes not fully opened up for astronomical studies. Thanks both to improvements in detectors and receivers and to the construction of large telescopes at high altitude sites this situation is improving very rapidly. Three major telescopes have been built recently and are coming into operation during 1987 and 1988, namely the 15m James Clerk Maxwell Telescope (JCMT) and the lOAm Caltech Submillimetre Observatory (CSO) telescope, both located on Mauna Kea, Hawaii, and the 15 m Swedish -ESO telescope (SEST) in Chile. Because a very wide range of astronomical problems can be tackled with these major new facilities there is a great deal of interest from the many potential new users anxious to become familiar with this rapidly developing field. During 1986 it became clear to British and Dutch astronomers involved in planning the commissioning and operation of the JCMT, that a summer school in this field would greatly benefit the potential and actual JCMT user community. With financial support from the SERC and supplemented by a grant from the ZWO, the Summer School on 'Millimetre and Submillimetre Astronomy' was held at Stirling University from June 21 to 27, 1987.

Written by leading exponents in the field, this collection of timely reviews presents observational methods and the latest results of astronomical research as well as their theoretical foundations and interrelations, providing information and scientifically rigorous coverage.

Replacement of a failing hip joint or other defective organs in the human body by artificial 'spare parts' has significantly improved our quality of life. These spare parts have to meet a wide spectrum of mechanical, chemical and design requirements. In this book, the properties and selection of materials for such `spare parts' are deduced from case studies at the start of each chapter. Hard tissue replacements (joints, long bones, dental), soft tissue (heart valves) and tissue engineering are included. The chapters also detail the three generic classes of materials: alloys (including shape memory alloys), ceramics & glasses and polymers. Separate chapters are devoted to the toxicity of implants, the metals zirconium(-zirconium oxide), tantalum, niobium and metallic glasses, soluble metals and Rapid Prototyping techniques for the fabrication of custom made prostheses. The book concludes by a chapter on water as water is always 'there' and conditions the interaction between body and implant. Water is the very matrix of life on earth. A peculiarity of the book is its 'perspective view', meaning that the authors looked behind the present biomaterials' decor and included historical backgrounds (real and mythological), future developments, and the relation to nature (plants and geology).

This thesis addresses two of the central processes which underpin the formation of galaxies: the formation of stars and the injection of energy into the interstellar medium from supernovae, called feedback. In her work Claudia Lagos has completely overhauled the treatment of these processes in simulations of galaxy formation. Her thesis makes two major breakthroughs, and represents the first major steps forward in these areas in more than a decade. Her work has enabled, for the first time, predictions to be made which can be compared against new observations which probe the neutral gas content of galaxies, opening up a completely novel way to constrain the models. The treatment of feedback from supernovae, and how this removes material from the interstellar medium, is also likely to have a lasting impact on the field. Claudia Lagos Ph.D. thesis was nominated by the Institute for Computational Cosmology at Durham University as an outstanding Ph.D. thesis 2012.

oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar macological targets in the treatment of a variety of disorders, such as epi lepsy, hypertension, and pain. Voltage-gated calcium channels have there fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac tivity, the book delves into a provocative overview of the history of the cal cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat ing, permeation, modulation and interactions with members of the exo- totic machinery-contributed by both established leaders and rising stars in the field."

Cold atmospheric plasma is an auspicious new candidate in cancer treatment. Cold atmospheric plasma (CAP) is a partially ionized gas in which the ion temperature is close to room temperature. It contains electrons, charged particles, radicals, various excited molecules and UV photons. These various compositional elements have the potential to inhibit cancer cell activity whilst doing no harm to healthy cells. Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults; treatment including surgery, radio- and chemotherapy remains palliative for most patients as a cure remains elusive. The successful combination of the standard chemotherapeutic temozolomide (TMZ) and CAP treatment features synergistic effects even in resistant glioma cells. In particular in glioma therapy, CAP could offer an innovative approach allowing specific cancer cell / tumor tissue inhibition without damaging healthy cells. Thus CAP is a promising candidate for combination therapy especially for patients suffering from GBMs showing TMZ resistance.

Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic and structural resolution. The most commonly used approaches rely on rapid mixing methods to initiate the folding event via a sudden change in solvent conditions. Traditionally, techniques such as fluorescence, circular dichroism or visible absorption are applied to probe the process. In contrast to these techniques, infrared spectroscopy came into play only very recently, and the progress made in this field up to date which now permits to probe folding events over the time scale from picoseconds to minutes has not yet been discussed in a book. The aim of this book is to provide an overview of the developments as seen by some of the main contributors to the field. The chapters are not intended to give exhaustive reviews of the literature but, instead to illustrate examples demonstrating the sort of information, which infrared techniques can provide and how this information can be extracted from the experimental data. By discussing the strengths and limitations of the infrared approaches for the investigation of folding and misfolding mechanisms this book helps the reader to evaluate whether a particular system is appropriate for studies by infrared spectroscopy and which specific advantages the techniques offer to solve specific problems.

Star clusters are at the heart of astronomy, being key objects for our understanding of stellar evolution and galactic structure. Observations with the Hubble Space Telescope and other modern equipment have revealed fascinating new facts about these galactic building blocks. This book provides two comprehensive and up-to-date, pedagogically designed reviews on star clusters by two well-known experts in the field. Bruce Carney presents our current knowledge of the relative and absolute ages of globular clusters and the chemical history of our Galaxy. Bill Harris addresses globular clusters in external galaxies and their use as tracers of galaxy formation and cosmic distance indicators. The book is written for graduate students as well as professionals in astronomy and astrophysics.

This book highlights the overview of the COVID-19 pandemic from both the scientific and the social perspectives. The scientific part presents key facts of COVID-19, including the structure of the virus and the techniques for the diagnosis, treatment, and vaccine development against the disease, covering state-of-the-art findings and achievements worldwide. The social part is written by WHO professionals who worked on the frontier of the fight against the disease. It covers the global security situation during the pandemic, the WHO and governmental-level risk management measures, and the estimated impact that COVID-19 will eventually create on social life after it is globally controlled.

This book introduces the use of industrial CMOS processes to produce arrays of nanomechanical cantilever transducers with on-chip driving and signal conditioning circuitry. These cantilevers are familiar from Scanning Probe Microscopy (SPM) and allow the sensitive detection of physical quantities such as forces and mass changes. The book is divided into three parts. First fabrication aspects and the mechanisms of cantilever resonators are introduced. Of the possible driving and sensing mechanisms, electrothermal and magnetic excitation, as well as piezoresistive detection and the use of MOS transistors for the deflection detection are introduced. This is followed by two application examples: The use of resonant cantilevers for the mass-sensitive detection of volatile organic compounds, and force sensor arrays for parallel Scanning Atomic Force Microscopy (AFM) of large areas.

The Earth's atmosphere is often portrayed as a thin and finite blanket covering our planet, separate from the emptiness of outer space. In reality, the transition is gradual and a tiny fraction of the atmophere gases is still present at the altitude of low orbiting satellites. The very high velocities of these satellites ensure that their orbital motion can still be considerably affected by air density and wind. This influence can be measured using accelerometers and satellite tracking techniques. The opening chapters of this thesis provide an excellent introduction to the various disciplines that are involved in the interpretation of these observations: orbital mechanics, satellite aerodynamics and upper atmospheric physics. A subsequent chapter, at the heart of this work, covers advances in the algorithms used for processing satellite accelerometry and Two-Line Element (TLE) orbit data. The closing chapters provide an elaborate analysis of the resulting density and wind products, which are generating many opportunities for further research, to improve the modelling and understanding of the thermosphere system and its interactions with the lower atmosphere, the ionosphere-magnetosphere system and the Sun.

A collection of sixteen coordinated reviews on the origins of large-scale magnetic fields in the Universe, this book discusses magnetic fields in all relevant astrophysical contexts, from the interstellar medium to the scales of galaxies and clusters of galaxies. Magnetic fields are described in their very diverse environments, from stellar winds to galactic haloes and astrophysical jets; together with the roles they play in forming the structures and shaping the dynamics of these objects. Both observational evidence and its theoretical interpretations are covered up to the largest scales in the Universe. The authors are all leading scientists in their fields, making this book an authoritative, up-to-date and enduring contribution to astrophysics. This volume is aimed at graduate students and researchers in astrophysics. Previously published in Space Science Reviews journal, Vol. 166/1-4 and Vol. 169/1-4, 2012.