The germ plasm of numerous plant species, especially those of forest trees, some agricultural crops, and medicinal plants, is endangered and threatened with extinction. This depletion of germplasm pools and the shrinkage of naturally occurring genetic resources have caused international concern. Conventionally, the germplasm of plants is conserved through seeds, tubers, roots, corms, rhizomes, bulbs, cuttings, etc. However, the germ plasm of a number of trees and plantation crops (such as coconut, cocao, coffee, oil palm, rubber, mango, horse chestnut, etc. ) cannot be preserved since their seed are short-lived (recalcitrant). Likewise, germplasm of vegetatively propagated crops (such as potato and cassava) cannot be stored on a long term basis and has to be grown and multiplied periodically in nurseries and fields. The plants are thus exposed to unpredictable weather conditions and diseases, with the result that instances are known where entire genetic stocks are lost. Therefore, unconventional methods are being developed for the storage and international exchange of germplasm. For this purpose in vitro cultures have been employed, but they can only enable short-to medium term preservation; moreover, cell cultures upon repeated subculture undergo genetic erosion. In view of the recent developments in the in vitro induction of genetic variability through somaclonal variation, somatic hybridization, recombinant DNA technology, etc., new methods need to be employed for the storage of desirable cultures. In this regard freeze preservation of cells in liquid nitrogen (-196 0q, like that of semen, enables long-term storage, theoretically, for an indefinite period of time."

This book demonstrates the usefulness of tools from statistical mechanics for biology. It includes the new tendencies in topics like membranes, vesicles, microtubules, molecular motors, DNA, protein folding, phase transitions in biological systems, evolution, population dynamics, neural systems and biological oscillators, with special emphasis on the importance of statistical mechanics in their development. The book addresses researchers and graduate students.

Many important observational clues about our understanding of how stars and planets form in the interior of molecular clouds have been amassed using recent technological developments. ESO's very large telescope promises to be a major step forward in the investigation of stellar nurseries and infant stars. This volume collects papers from the leaders in this very timely field of astrophysical research. It presents theoretical and a host of observational results and many papers show the plans for future observations.

This book assembles chapters from experts in the Biophysics of RNA to provide a broadly accessible snapshot of the current status of this rapidly expanding field. The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, highlighting just one example of a large number of non-protein coding RNAs. Because non-protein coding RNAs outnumber protein coding genes in mammals and other higher eukaryotes, it is now thought that the complexity of organisms is correlated with the fraction of their genome that encodes non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic transposons, higher-level organization of eukaryotic chromosomes, and gene expression itself are found to largely be directed by non-protein coding RNAs. The biophysical study of these RNAs employs X-ray crystallography, NMR, ensemble and single molecule fluorescence spectroscopy, optical tweezers, cryo-electron microscopy, and other quantitative tools. This emerging field has begun to unravel the molecular underpinnings of how RNAs fulfill their multitude of roles in sustaining cellular life. The physical and chemical understanding of RNA biology that results from biophysical studies is critical to our ability to harness RNAs for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.

Remote Sensing from a New Perspective The idea for this book began many years ago, when I was asked to teach a course on remote sensing. Not long before that time, I had been part of the effort to develop the first database for planetary data with a common digital array format and interactive processing capabilities to correlate those data easily: the lunar consortium. All the available lunar remote sensing data were included, orbital and ground-based, ranging across the entire electromagnetic spectrum. I had used this powerful tool extensively, and, in that spirit, I was determined to create a course which covered the entire spectrum and a variety of targets. As I looked around for the equivalent of a textbook, which I was willing to pull together from several sources, I realized that available material was very heavily focused on the visual and near visual spectrum and on the Earth as a target. Even The Surveillant Science, edited by Edward Holz and published in 1973, which broke new ground in having diverse articles on most of the spectrum when it was created, focused entirely on the Earth. My personal favorite, the exceedingly well written book on remote sensing by Floyd Sabins first published in 1978, covered the visual, infrared, and microwave portions of the spectrum beautifully but focused on the Earth as well. Unhindered, I developed what I called 'packets' of material for each part of the spectrum.

This book describes origin and characteristics of the Earth's thermal field, thermal flow propagation and some thermal phenomena in the Earth. Description of thermal properties of rocks and methods of thermal field measurements in boreholes, underground, at near-surface conditions enables to understand the principles of temperature field acquisition and geothermal model development. Processing and interpretation of geothermal data are shown on numerous field examples from different regions of the world. The book warps, for instance, such fields as analysis of thermal regime of the Earth's crust, evolution and thermodynamic conditions of the magma-ocean and early Earth atmosphere, thermal properties of permafrost, thermal waters, geysers and mud volcanoes, methods of Curie discontinuity construction, quantitative interpretation of thermal anomalies, examination of some nonlinear effects, and integration of geothermal data with other geophysical methods. This book is intended for students and researchers in the field of Earth Sciences and Environment studying thermal processes in the Earth and in the subsurface. It will be useful for specialists applying thermal field analysis in petroleum, water and ore geophysics, environmental and ecological studies, archaeological prospection and climate of the past.

Provides a description of the thermodynamic model, data treatment procedures and the thermodynamic constants for hydrous ferric oxide. Includes detailed coverage of the model and the parameter extraction procedure.

Audouin Dollfus Observatoire de Paris, Section de Meudon, 92195 Meudon, FRfu CE The North Atlantic Treaty Organization (NATO) and, in particular, its Department of Scientific Affairs headed by Dr. C. Sinclair, actively supports new fields of science. The recent exploration of the outer parts of the Solar System by spacecraft focused the attention of a large community of scientists on the problem of ices, which playa major role in the accretionary processes in space except for the close neighborhood of the Sun and of other stars. NATO responded to this new interest by agreeing to sponsor an Advanced Research Workshop "Ices in the Solar System," provided a proper organizing body could be set up. It was a pleasure to organize such a workshop jointly with Profes sor Roman Smoluchowski who had earlier organized similar conferences. I knew from the experience of others who managed such meetings in the past that there would be much work, but the opportunity of cooperating with Smoluchowski was very attractive and convinced me to agree. If well organized, the whole project promised to be more than rewarding for a large community of scientists, both in the short run and in the long run, by clarifying certain outstanding questions in astrophysics. It became clear that a well-organized international conference would attract top scientists and help unravel many fundamental problems."

The Andromeda Galaxy, or M31, is an attractive galaxy for astronomers. It is close to us, it is of about the size of our galaxy, it provides some intriguing observational puzzles because the galaxy is nearly edge-on, and many objects can be studied in detail, because they are still sufficiently bright. With the current developments in instrumentation with which increasingly detailed studies of the Andromeda Galaxy can be made, this book provides a solid foundation for the start of new observations. This book is a mine of information about M31. It can be used as a reference by insiders, and at the same time it provides easy access for newcomers to the field.

The discovery of the earth's radiation belts in 1957 marked the beginning of what is now known as magnetospheric physics. The field has evolved normally from an early discovery phase through a period of exploration and into an era of quantitative studies of the dynamics of magnetized plasmas as they occur in nature. Such environments are common throughout the universe and have been studied in varying detail at the sun, the planets, pulsars, and certain radio galaxies. The purpose of this book is to describe basic quantitative aspects of magnetospheric physics. We use selected examples from the earth's magnetosphere to show how theory and data together form a quantitative framework for magnetospheric research. We have tried to organize the material along the philosophy of starting simply and adding com plexity only as necessary. We have avoided controversial and relatively new research topics and have tried to use as examples physical processes generally accepted as important within the earth's magnetospheric system. However, even in some of our examples, the question of whether the physical process applied to a particular problem is the dominant process, has yet to be answered."

This thesis describes the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens. The study presented shows that calcium can regulate the signal pathway in cells not only as a secondary messenger but also through direct interactions with the phospholipid bilayer. The approach used in the thesis also represents an important advance, as it couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells. Moreover, the thesis optimizes the Nanodisc assembly protocol, which can broaden its range of applications in membrane protein studies. A preliminary study on the structure of dengue virus NS2B-NS3p in complex with aprotinin, which may help to develop new drugs against the dengue virus, is also included.

This is a compilation of manuscripts on mineral and thermal waters of different areas of the world.
This special volume is devoted to the 41st Meeting of the This is a compilation of manuscripts on mineral and thermal waters of different areas of the world.
This special volume is devoted to the 41st Meeting of the Commission on Mineral and Thermal Waters of International Association of Hydrogeologists (IAH-CMTW) held in Cairo, Egypt, in October 2009. The presentations collected and presented in this volume show the variety of aspects of mineral and thermal waters occurrence and utilization in different countries of the world with a special focus on Egypt, Iran, Ukraine, Poland, Russia and Australia.

The book sets out to inform a broad range of professionals working in medicine and healthcare about how creative thinking and design concepts can be used to innovate in providing an enhanced patient experience. It outlines these concepts as a primary means to identify, clarify and resolve some of the process improvement and enhancement challenges in healthcare delivery. It demonstrates by example how such challenges can be addressed, drawing on case examples from healthcare and other industries, and from the authors’ own experiences as innovators and educators. It emphasizes the value of learning in action. For the reader who already has a leaning towards novel approaches to addressing healthcare delivery challenges, it provides guidance on harnessing team inputs and engaging with a network of contributors. It is an ideal resource for all working in medicine and healthcare, from managers, nurses, doctors, administrators, executives, and allied health professionals to medical engineers, medical physicists, medical scientists and medical product developers. Features Provides a unique framework to conceptualise innovation in healthcare and medicine. Authored by an award-winning medical scientist and an established business school Professor who have proven track-records with innovation, in education settings and as entrepreneurs. Presents a clear interdisciplinary approach, complemented with practical case studies set in the context of the challenges facing healthcare delivery in the 21st century. Dr. Barry McMahon has a national and international reputation as an Academic Medical Physicist in the fields of novel physiological measurement and medical device innovation and design. He is the co- inventor of the Functional Lumen Imaging Probe (FLIP) technique later commercialised as EndoFLIP™. He was the Director of the Innovation Academy at Trinity College Dublin from 2012 to 2017. Since 2020 he is advising Children’s Health Ireland on innovation practice. In 2021, he retired as Chief Physicist/Clinical Engineer at Tallaght Hospital, Ireland and currently runs his own innovation-consulting group Electric Mindset Ltd. Dr. Paul Coughlan is Professor in Operations Management and Co-Director of Faculty at Trinity Business School, Trinity College Dublin. His research explores collaborative strategic improvement of operations through network action learning. He was the Director of the Innovation Academy at Trinity College Dublin from 2010 to 2012. He is a founding director of a research-based spin-out venture, Easy Hydro Ltd.

This timely book presents an overview of the galaxies within the Local Volume, including the Local Group and our closest neighbours, the Andromeda Galaxy and the Magellanic Clouds. Presented here are the latest results from radio, infrared and optical surveys as well as detailed multi-wavelength studies of individual galaxies. The book aims to provide a vibrant forum for presentations and discussions across a broad range of astrophysical topics.

This book provides a comprehensive presentation of Earth s energy flows and their consequences for the climate. The Earth s climate as well as planetary climates in general, are broadly controlled by three fundamental parameters: the solar irradiance, the planetary albedo and the planetary emissivity. Space measurements indicate that these three quantities are remarkably stable. A minor decrease inplanetary emissivity is consistent with theoretical calculations. This is due to the ongoing increase of atmospheric greenhouse gases making the atmosphere more opaque to long wave terrestrial radiation. As a consequence radiation processes are slightly out of balance as less heat is leaving the Earth in the form of thermal radiation than the incoming amount of heat from the sun. Present space-based systems cannot yet satisfactorily measure this imbalance, but the effect can be inferred from the measurements of the increase of heat in the oceans. Minor amounts of heat are also used to melt ice and to warm the atmosphere and the surface of the Earth.
The book brings to fore the complexity of feedback processes of the Earth s climate system and in particular the way clouds and aerosols affect the energy balance both directly and indirectly through feed-back loops driven by the dynamics of atmospheric, ocean and land surface processes. The book highlights recent scientific progress as well as remaining challenges.
Previously published in Surveys in Geophysics, Volume 33, Nos. 3-4, 2012"

Lissajous Figures are produced by combining two oscillations at right angles to each other. The figures, drawn by mechanical devices called Harmonographs, have scientific uses, but are also enjoyed for their own beauty. The author has been working with harmonographs since his undergraduate days, has built several of them, lectured about them and has written articles about them. This book is intended for people who enjoy physics or art or both. Certainly physics professionals, both students and faculty members, will enjoy reading about an interesting byway of physics. The book is mainly designed for the reader who has some scientific literacy, but who may not be a scientist. If your mathematics is rusty, a preliminary section on mathematics supplies the necessary background for reading the rest of the book.

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles.While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

IAU Symposium No. 134 on Active Galactic Nuclei was hosted by the Lick Observatory, as part of the celebration of its centennial, for the Observatory went into operation as part of the University of California on June 1, 1888. Twenty years later, in 1908, Lick Observatory graduate student Edward A. Fath recognized the unusual emission-line character of the spectrum of the nucleus of the spiral "nebula" NGC 1068, an object now well-known as one of the nearest and brightest Seyfert galaxies and active galactic nuclei. Ten years after that, and seventy years before this Symposium, Lick Observatory faculty member Heber D. Curtis published his description of the "curious straight ray" in M 87, "apparently connected with the nucleus by a thin line of matter," which we now recognize as an example of one of the jets which are the subject of so much current AGN research. The symposium was held at Kresge College on the campus of the University of California, Santa Cruz, only a short walk through the redwood groves to the Lick Observatory offices. A total of 232 astronomers and astrophysicists from 24 countries attended and took part in the Symposium. About 200 more had applied to come, but could not be accepted in order to keep the meeting at a reasonable size. Most of the participants lived in the Kresge College apartments immediately adjacent to the Kresge Town Hall in which the oral sessions took place.

Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications.

Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.

This NATO Advanced Study Institute course provided an updated understanding, from a fundamental and deep point of view, of the progress and current problems in the early universe, cosmic microwave background radiation, large-scale struc ture, dark matter problem, and the interplay between them. Emphasis was placed on the mutual impact of fundamental physics and cosmology, both at the theo retical and experimental or observational levels, within a deep and well defined programme, and a global unifying view, which, in addition, provides of careful inter-disciplinarity. In addition, each course of this series introduced and promoted topics or sub jects which, although not of a purely astrophysical or cosmological nature, were of relevant physical interest for astrophysics and cosmology. Deep understanding, clarification, synthesis, and careful interdisciplinarity within a fundamental physics framework, were the main goals of the course. Lectures ranged from a motivation and pedagogical introduction for students and participants not directly working in the field to the latest developments and most recent results. All lectures were plenary, had the same duration, and were followed by a discus sion. The course brought together experimentalists and theoreticans physicists, astro physicists and astronomers from a wide variety of backgrounds, including young scientists at the post-doctoral level, senior scientists and advanced graduate stu dents as well."

This thesis focuses on the theoretical foundation of the Standard Model valid up to the Planck scale, based on the current experimental facts from the Large Hadron Collider. The thesis consists of two themes: (1) to open up a new window of the Higgs inflation scenario, and (2) to explore a new solution to the naturalness problem in particle physics. In the first area, on the Higgs inflation scenario, the author successfully improves a large value problem on a coupling constant relevant to the Higgs mass in the Standard Model, in which the coupling value of the order of 105 predicted in a conventional scenario is reduced to the order of 10. This result makes the Higgs inflation more attractive because the small value of coupling is natural in the context of ultraviolet completion such as string theory. In the second area, the author provides a new answer to the naturalness problem, of why the cosmological constant and the Higgs mass are extremely small compared with the Planck scale. Based on the baby universe theory originally proposed by Coleman, the smallness of those quantities is successfully explained without introducing any additional new particles relevant at the TeV energy scale.

Proceedings of the 128th Symposium of the International Astronomical Union, held in Coolfont, West Virginia, USA, October 20-24, 1986.