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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine

Counselling for Heart Disease (Paperback): Paul Bennett Counselling for Heart Disease (Paperback)
Paul Bennett
R1,082 Discovery Miles 10 820 Ships in 12 - 17 working days

Coronary Heath Disease reminds the leading cause of premature death in most western countries, accounting, in the UK, for 40 percent of deaths in men and 10 percent of deaths in women, aged between 45 and 64 years. The psychological and social impact of heart disease can have adverse effects on the individual, the family and the disease itself, whilst a heart attack might involve not only an immediate threat to life, but also loss of a sense of control.

This book provides a practical framework for supporting and helping the patient and the family both in the acute medical setting and in the longer term in the community. It focuses on skills and techniques needed to provide important information, reduce stress and to set realistic goals during rehabilitation. The role of open communication between helper and patient is emphasized and demonstrated using examples and case studies.

This book has been written for all concerned with heart disease: professionals and lay helpers, clinicians and non-clinicians.

The Foreword is by Dr Alastair McDonald of the Cardiac Department, The Royal London Hospital, who also acted as medical advisor for the book.

The Complete Reference for Scimitar Syndrome - Anatomy, Epidemiology, Diagnosis and Treatment (Paperback): Vladimiro Vida The Complete Reference for Scimitar Syndrome - Anatomy, Epidemiology, Diagnosis and Treatment (Paperback)
Vladimiro Vida
R3,419 R3,102 Discovery Miles 31 020 Save R317 (9%) Ships in 12 - 17 working days

The Complete Reference for Scimitar Syndrome: Anatomy, Epidemiology, Diagnosis and Treatment gives the complete picture of this rare syndrome that is usually treated with tactics such as imaging. The book goes beyond imaging, providing a pathological and clinical description of this rare syndrome. All aspects beginning with development, clinical presentation, current surgical options (including recent techniques) and indications to treat patients based on current results coming from multicenter study experiences are included. This book is a must-have reference for all cardiologists, cardiac surgeons, thoracic surgeons, pathologists, physicians, residents and students involved in Scimitar Syndrome cases.

Hypertension: A Companion to Braunwald's Heart Disease (Hardcover, 3rd edition): George L. Bakris, Matthew Sorrentino Hypertension: A Companion to Braunwald's Heart Disease (Hardcover, 3rd edition)
George L. Bakris, Matthew Sorrentino
R2,025 Discovery Miles 20 250 Ships in 12 - 17 working days

The third edition of Hypertension: A Companion to Braunwald's Heart Disease, by Drs. George L. Bakris and Matthew Sorrentino, focuses on every aspect of managing and treating patients who suffer from hypertensive disorders. Designed for cardiologists, endocrinologists and nephrologists alike, this expansive, in-depth review boasts expert guidance from contributors worldwide, keeping you abreast of the latest developments from basic science to clinical trials and guidelines. Hypertension also includes an Expert Consult eBook updated with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald. Features expert guidance from worldwide contributors in cardiology, endocrinology, neurology and nephrology. Covers behavior management as an integral part of treatment plans for hypertensives and pre-hypertensives. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, videos, and references from the book on a variety of devices. Covers new developments in epidemiology, pathophysiology, immunology, clinical findings, laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, prognosis, and management. Includes chapters on hot topics such as hypertension as an immune disease; sleep disorders including sleep apnea, a major cause of hypertension; a novel chapter on environmental pollution and its contribution to endothelial dysfunction, and more! Equips you with the most recent guidelines from the major societies. Updates sourced from the main Braunwald's Heart Disease text. Highlights new combination drug therapies and the management of chronic complications of hypertension.

Congenital Cardiac Anesthesia - A Case-based Approach (Hardcover): Laura K. Berenstain, James P. Spaeth Congenital Cardiac Anesthesia - A Case-based Approach (Hardcover)
Laura K. Berenstain, James P. Spaeth
R2,429 R2,288 Discovery Miles 22 880 Save R141 (6%) Ships in 12 - 17 working days

With the number of patients living with congenital heart disease steadily increasing, relevant training in anesthesia care for these patients is becoming ever more important. Written by experts in the field, this highly illustrated book succinctly reviews the pathophysiology of congenital cardiac lesions along with important anesthetic implications for each. Case scenarios cover patients of wide-ranging ages, with a focus on care in non-cardiac operating room settings, including the general operating room, cardiac catheterization laboratory and radiology. Divided into sections corresponding to the anatomic classification of each cardiac lesion, the book includes keywords for easy cross-referencing. Several lesions have multiple scenarios presented in order to allow readers to learn how to discern more critically ill patients. The stepwise approach to understanding complex lesions provides a readily accessible guide for all anesthesia providers who care for patients with congenital heart disease. The book is also a useful tool for intraoperative teaching.

Peripheral Artery Disease (PAD) - Risk Factors, Diagnosis & Emerging Treatments (Hardcover): Neeraj N Shah, Jalaj Garg Peripheral Artery Disease (PAD) - Risk Factors, Diagnosis & Emerging Treatments (Hardcover)
Neeraj N Shah, Jalaj Garg
R3,347 Discovery Miles 33 470 Ships in 12 - 17 working days

This is a concise summary of information on the incidence, diagnosis, classification and non-surgical treatment of peripheral artery disease (PAD). PAD imposes a significant burden on health care system. Patients suffering from PAD have leg pains, difficulty walking, and lower extremity ulcers. If untreated, this condition can result in limb loss. It is both a life and a limb-threatening condition. It is important to recognise this condition early on, even in the absence of symptoms, in order to provide the best possible therapy in a timely manner. Early and aggressive treatment of PAD is crucial for limb salvage. The surgical therapeutic options for PAD are well-known and described in the literature; however, the information on medical and other non-surgical options for PAD is scattered and not well-summarised. In this book, the authors have attempted to assimilate and summarise in one place all the available information regarding the epidemiology of PAD, clinical features of the disease, clinical and anatomical classification of PAD, medications used to treat PAD, role of fish oil supplementation in PAD and the endovascular therapeutic options for PAD. The authors have summarised the latest available endovascular interventional strategies for the management of aortoiliac, femoropopliteal as well as infrapopliteal PAD. Peripheral vascular intervention is an exciting and ever-changing field, and the authors have attempted to synthesise information from all the major and relevant studies in this field. The authors hope that their book serves as a valuable reference resource for clinicians who are actively involved in the management of patients suffering from PAD, including primary care physicians, cardiologists, vascular surgeons, and cardiovascular fellows in training.

Making Sense of the ECG - A Hands-On Guide (Paperback, 5th edition): Andrew Houghton Making Sense of the ECG - A Hands-On Guide (Paperback, 5th edition)
Andrew Houghton
R765 Discovery Miles 7 650 Ships in 9 - 15 working days

Interpreting an ECG correctly and working out what to do next can seem like a daunting task to the non-specialist, yet it is a skill that will be invaluable to any doctor, nurse or paramedic when evaluating the condition of a patient. Making Sense of the ECG has been written specifically with this in mind, and will help the student and more experienced healthcare practitioner to identify and answer crucial questions. This popular, easy-to-read and easy-to-remember guide to the ECG as a tool for diagnosis and management has been fully updated in its fifth edition to reflect the latest guidelines.

Aneurysms-Osteoarthritis Syndrome - SMAD3 Gene Mutations (Paperback): Denise Van der Linde, Jolien Roos-Hesselink, Bart L. Loeys Aneurysms-Osteoarthritis Syndrome - SMAD3 Gene Mutations (Paperback)
Denise Van der Linde, Jolien Roos-Hesselink, Bart L. Loeys
R3,024 R2,751 Discovery Miles 27 510 Save R273 (9%) Ships in 12 - 17 working days

Aneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations is a first-of-its-kind compilation of the genetic discovery, research, and care associated with AOS. With the field of genetically triggered aortopathies growing, this important reference will compile the newest discoveries in this field, allowing cardiologists, cardio-thoracic surgeons, clinical geneticists, vascular surgeons, orthopedic surgeons, and researchers to gain the knowledge they need without having to gather the data from various sources. Coverage includes genotype and phenotype correlations, the functional role of SMAD3, and insights into the role of TGFbeta signaling in aortic disease. The book will increase knowledge about AOS, providing awareness and better patient care for this aggressive disease.

ECMO-Extracorporeal Life Support in Adults (Hardcover, 2014 ed.): Fabio Sangalli, Nicolo Patroniti, Antonio Pesenti ECMO-Extracorporeal Life Support in Adults (Hardcover, 2014 ed.)
Fabio Sangalli, Nicolo Patroniti, Antonio Pesenti
R5,820 R5,259 Discovery Miles 52 590 Save R561 (10%) Ships in 12 - 17 working days

Extracorporeal membrane oxygenation (ECMO) has been in clinical use for some 40 years, but it is only in the past decade that its application in the treatment of life-threatening circulatory and respiratory failure has truly flourished. This book presents a comprehensive overview of both pathophysiological and practical aspects of circulatory and respiratory extracorporeal support. The basics of ECMO, including its history, the "ECMO team," cannulation, materials, and blood- surface interactions, are first discussed. The various indications for and particular characteristics of circulatory and respiratory extracorporeal life support are then described in detail in the main part of the book. Patient care during ECMO and monitoring of the ECMO patient are also carefully covered, with explanation of the management of technical and clinical complications and transport-related problems. Further topics include long-term therapy options beyond ECMO, such as ventricular assist devices and transplants, outcome, the new frontiers of ECMO for organ procurement and future challenges. The authors are well-known experts in the field whose authoritative contributions and attention to practical aspects will be invaluable for novices and experienced practitioners alike.

Diseases of the Aorta (Hardcover, 1st ed. 2019): Robert S. Dieter, Raymond A. Dieter Jr., Raymond A. Dieter III Diseases of the Aorta (Hardcover, 1st ed. 2019)
Robert S. Dieter, Raymond A. Dieter Jr., Raymond A. Dieter III
R5,048 R4,305 Discovery Miles 43 050 Save R743 (15%) Ships in 12 - 17 working days

This book examines various aspects of the aorta, both healthy and diseased states, in 40 chapters of in-depth research by experts in cardiovascular disease. It begins with chapters on the embryology, anatomy, genetics, and physiology of the aorta along with imaging studies used to visualize its structure. The bulk of the book focuses on acute and chronic disorders such as coarctation of the aorta, inflammatory and connective tissue disorders, acute aortic thrombosis, infections, tumors, related ocular diseases, and various aneurysms and fistulas. In addition, it explores aortic disease in pregnancy, fetal aortic disorders, and aortic trauma in children. The book highlights the epidemiology and natural history as well as medical, endovascular, and surgical treatments for each disease. It also discusses valve repair, 3D printing applications, and the role of multidisciplinary aortic centers. Diseases of the Aorta is an indispensable and authoritative resource for cardiologists, cardiovascular surgeons, interventional radiologists, radiologists, and vascular medicine specialists.

Horizons in World Cardiovascular Research - Volume 9 (Hardcover): Eleanor H Bennington Horizons in World Cardiovascular Research - Volume 9 (Hardcover)
Eleanor H Bennington
R5,724 Discovery Miles 57 240 Ships in 12 - 17 working days

This book provides readers with the latest developments in cardiovascular research. Topics covered include an analysis of the effectiveness of newer drugs when compared to Warfarin in reducing the mortality and complications from atrial fibrillation; the epidemiological differences and evolution of high-risk acute coronary syndrome in men and women; cardiovascular control via the vestibular system; an alternative view on inflammation and the endothelium, which plays a crucial role for different substantial vascular functions; the epidemiology, physiopathology and the diagnosis and treatment of renovascular hypertension; a therapeutic approach to treating hypovolemic shock; pathological findings, diagnostic strategies and treatment of left ventricular pseudoaneurysm (LVPA); the structure, development and functions of sarcalumenin, a glycoprotein involved in skeletal and cardiac muscles; hybrid coronary revascularization and the dietary factors that play an important role in the modulation of hypertension - the fourth contributor to premature death in developed countries and the seventh in developing countries.

Heart Failure, An Issue of Critical Nursing Clinics, Volume 27-4 (Hardcover, UK ed.): Jennifer Kitchens Heart Failure, An Issue of Critical Nursing Clinics, Volume 27-4 (Hardcover, UK ed.)
Jennifer Kitchens
R1,731 Discovery Miles 17 310 Ships in 12 - 17 working days

Heart failure is the only cardiovascular disease that is increasing. The impact on the critical care environment and the health care system, as a whole, is significant from both a cost and burden to the system perspective. There are 6.5 million hospital days a year and nearly $40 billion dollars in yearly health care costs attributed to heart failure in the United States. There are more Medicare monies spent for diagnosing and treating heart failure than any other Diagnosis Related Group. There is a 24% hospital re-admission rate for this diagnosis which leads to financial implications for health care systems. The human cost is also significant. Less than half of Americans diagnosed with heart failure survive greater than 5 years. The ongoing health care needs and cost of this chronic disease takes a significant toll on patients' finances, time and quality of life. Over $2.9 billion dollars is spent annually on the pharmaceutical management of heart failure in the United States. This diagnosis is the leading cause of hospitalization for patients who are 65 years of age and older. Few health care providers in the critical care environment are not affected by heart failure on a routine basis. Caring for these patients and their families is both a challenging and yet a rewarding experience. This edition will provide critical care nurses with a comprehensive heart failure review which is essential in caring for this challenging population given the dynamic health and critical care environments.

Coronary Artery Disease, An Issue of Heart Failure Clinics, Volume 12-1 (Hardcover, UK ed.): David Shavelle Coronary Artery Disease, An Issue of Heart Failure Clinics, Volume 12-1 (Hardcover, UK ed.)
David Shavelle
R1,737 Discovery Miles 17 370 Ships in 12 - 17 working days

Coronary artery disease continues to be a major cause of morbidity and mortality in the United States and throughout the world. This issue of the Heart Failure Clinics provides a contemporary and concise, yet extensive, review on all aspects of the management of patients with coronary artery disease. Topics include but are not limited to: Epidemiology, Traditional and Novel Risk Factors in Coronary Artery Disease; Acute Coronary Syndromes: Unstable Angina and Non-ST Elevation Myocardial Infarction; Calcium Scoring and Cardiac Computed Tomography; Coronary Artery Disease and Diabetes Mellitus; Cardiac Syndrome X; and Revascularization Options: Coronary Artery Bypass Surgery and Percutaneous Coronary Intervention.

Core Topics in Cardiothoracic Critical Care (Hardcover, 2nd Revised edition): Kamen Valchanov, Nicola Jones, Charles W. Hogue Core Topics in Cardiothoracic Critical Care (Hardcover, 2nd Revised edition)
Kamen Valchanov, Nicola Jones, Charles W. Hogue
R2,470 Discovery Miles 24 700 Ships in 12 - 17 working days

Most patients with critical cardiac or thoracic conditions will at some stage pass through the cardiothoracic critical care unit. Critical care presents more complex clinical data than any other area of medicine. The new edition of Core Topics in Cardiothoracic Critical Care focuses on the latest practise in the management of patients in cardiothoracic intensive care. The practice of cardiothoracic critical care medicine is constantly evolving, and this new edition reflects the modernized learning styles for trainees. Each chapter includes key learning points as well as sample multiple choice questions and answers to assist in exam preparation. This edition also features updated chapters on ECMO, perioperative management of patients undergoing emergency cardiothoracic surgery, and advanced modes of organ support for patients. This text provides key knowledge in a concise and accessible manner for trainees, clinicians and consultants from specialities and disciplines such as cardiology and anaesthesia, and nursing and physiotherapy.

Stroke Rehabilitation, An Issue of Physical Medicine and Rehabilitation Clinics of North America, Volume 26-4 (Hardcover, UK... Stroke Rehabilitation, An Issue of Physical Medicine and Rehabilitation Clinics of North America, Volume 26-4 (Hardcover, UK ed.)
John Chae
R1,872 R1,727 Discovery Miles 17 270 Save R145 (8%) Ships in 12 - 17 working days

This issue of Physical Medicine & Rehabilitation Clinics will focus on stroke rehabilitation and will include articles such as: Mechanisms of stroke recovery, Insights from basic sciences, Stroke recovery and predictors of rehabilitation outcomes, Upper limb motor impairments, Post-stroke spasticity, Communication disorders and dysphagia, Neuropharmacology of Recovery, Robotic therapy, and many more.

Transcatheter Mitral Valve Intervention, An Issue of Interventional Cardiology Clinics, Volume 5-1 (Hardcover, UK ed.): Jason H... Transcatheter Mitral Valve Intervention, An Issue of Interventional Cardiology Clinics, Volume 5-1 (Hardcover, UK ed.)
Jason H Rogers
R1,879 R1,734 Discovery Miles 17 340 Save R145 (8%) Ships in 12 - 17 working days

This issue of the Interventional Cardiology Clinics edited by Jason Rogers covers various approaches, techniques, and therapies for Transcatheter Mitral Value Intervention. Topics include, but are not limited to: Echocardiographic Imaging of the Mitral Valve for Transcatheter Interventions, Use of Computed Tomography to Guide Mitral Interventions, Transseptal Puncture for Mitral Interventions, MitraClip Therapy for Mitral Regurgitation: Primary MR, Coronary Sinus-Based Approach to Mitral Regurgitation, and Transcatheter Mitral Valve Replacement.

Plaque Imaging, An Issue of Neuroimaging Clinics of North America, Volume 26-1 (Hardcover, UK ed.): J Kevin DeMarco Plaque Imaging, An Issue of Neuroimaging Clinics of North America, Volume 26-1 (Hardcover, UK ed.)
J Kevin DeMarco
R1,746 Discovery Miles 17 460 Ships in 12 - 17 working days

This issue of Neuroimaging Clinics of North America focuses on Plaque Imaging. Articles will include: 3D carotid plaque MR imaging, Analysis of multi-contrast carotid plaque MR imaging, Incorporating carotid plaque imaging into routine clinical carotid MRA, PET-CT imaging to assess future cardiovascular risk, Utility of combining PET and MR imaging of carotid plaque, 3D carotid plaque ultrasound, Contrast-enhanced carotid plaque ultrasound, Detection of vulnerable plaque in patients with "cryptogenic stroke," Measuring plaque burden in secondary prevention of asymptomatic patients with known carotid stenosis, Plaque imaging in primary prevention of cardiovascular disease, Plaque imaging to decide on optimal treatment: medical versus CEA versus CAS, Clinical perspective of carotid plaque imaging, and more!

Clinical Guide to Cardiology (Paperback): C Camm Clinical Guide to Cardiology (Paperback)
C Camm
R1,022 Discovery Miles 10 220 Ships in 12 - 17 working days

Clinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology. It provides practical, evidence-based information on interventions, investigations, and the management of clinical cardiology. Key features include: A clear evidence-base providing key guidelines and clinical trials in each chapter Coverage of examination techniques, common conditions, imaging modalities (including ECGs, chest X-rays, MRI and CT), interventional therapies, and pharmacology A companion website at www.wiley.com/go/camm/cardiology featuring audio clips, developed for differing levels of knowledge, that explain key concepts or an area in greater detail, as well as numerous additional clinical case studies, audio scripts, and self-assessment material

Team-Based Care for Heart Failure, An Issue of Heart Failure Clinics, Volume 11-3 (Hardcover, 11 Ed): Gregg C. Fonarow Team-Based Care for Heart Failure, An Issue of Heart Failure Clinics, Volume 11-3 (Hardcover, 11 Ed)
Gregg C. Fonarow
R1,741 Discovery Miles 17 410 Ships in 12 - 17 working days

This issue of Heart Failure Clinics examines the critical role of team-based care in the management of patients with heart failure. Articles address Team-Based Care for Prevention, Patients Hospitalized with Heart Failure, Transitions of Care, Outpatients, Managing Cardiac Comorbidities, Managing Non-cardiac Conditions, Cardiac Rehabilitation and Exercise Training, External Telemonitoring, Ambulatory Hemodynamic Cardiac Device Monitoring, Advanced Heart Failure, and Palliative and End-of-Life Care.

Clinical Electrocardiography - A Textbook 5e (Hardcover, 5th Edition): A. Bayes de Luna Clinical Electrocardiography - A Textbook 5e (Hardcover, 5th Edition)
A. Bayes de Luna
R3,174 Discovery Miles 31 740 Ships in 12 - 17 working days

b>Clinical Electrocardiography Electrocardiography is a transthoracic recording over a period of time. Electrical activity is detected and recorded via electrodes attached to the outer surface of the skin. The recording produced by this noninvasive procedure is termed as electrocardiogram. ECGs are used to measure the rate and regularity of heartbeats as well as the size and position of the chambers, the presence of any damage to the heart, and the effects of drugs or devices used to regulate the heart. Clinical Electrocardiography is the clearest and most accessible guide available to the application and interpretation of the ECG in clinical practice. The book proceeds from the belief that ECG patterns should not be memorized, but rather must be understood based on how they originate; it is only by achieving this level of understanding that clinicians can make the most informed diagnoses and thus manage patient care with complete confidence. This fully revised 5th edition: Gives clear information about the correct diagnoses of different heart diseases based on ECG alterations. Presents an exceedingly clear and linear approach to understanding the application and interpretation of the ECG in clinical practice. Explains the electrical activity of the heart and basic electrocardiographic principals. Offers guidance on normal ECG patterns and the changes various heart diseases produce in ECG morphology Provides a practical, deductive approach to the diagnosis of arrhythmias - one of the most challenging tasks for many clinicians Summarizes current knowledge of the clinical implication of rhythmic disturbances.

Lipidology, An Issue of Cardiology Clinics, Volume 33-2 (Hardcover, 33 Ed): Edward A. Gill Lipidology, An Issue of Cardiology Clinics, Volume 33-2 (Hardcover, 33 Ed)
Edward A. Gill
R1,740 Discovery Miles 17 400 Ships in 12 - 17 working days

This issue of Cardiology Clinics examines the timely topic of Lipidology. In addition to the New Recommendations - ACC/AHA Lipid Guidelines, the issue also includes Familial Hypercholesterolemia; LDL Apheresis; Lipids in Pregnancy and Women; Diabetes and Lipidology; Diabetic Dyslipidemia; Fatty Liver Disease; Lipids and HIV Disease; Residual Risk; and Statins' effects on diabetes, cognition, and liver safety.

Understanding Hypertension Flip Chart (Spiral bound): Scientific Publishing Understanding Hypertension Flip Chart (Spiral bound)
Scientific Publishing
R555 Discovery Miles 5 550 Ships in 12 - 17 working days

Containing a selection of teaching tools for general anatomy and pathology, this work, with flip charts, offers an overview and understanding of the subject matter. It is useful for student or patient education. It is suitable for the home, the school library, or the physicians office and can be written on by a dry marker.

Translational Research in Coronary Artery Disease - Pathophysiology to Treatment (Paperback): Wilbert S. Aronow, John Arthur... Translational Research in Coronary Artery Disease - Pathophysiology to Treatment (Paperback)
Wilbert S. Aronow, John Arthur McClung
R2,769 Discovery Miles 27 690 Ships in 12 - 17 working days

Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source.

The Scientist's Guide to Cardiac Metabolism (Paperback): Michael Schwarzer, Torsten Doenst The Scientist's Guide to Cardiac Metabolism (Paperback)
Michael Schwarzer, Torsten Doenst
R1,989 Discovery Miles 19 890 Ships in 12 - 17 working days

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease.

Mesenchymal Stem Cell Derived Exosomes - The Potential for Translational Nanomedicine (Hardcover): Yaoliang Tang, Buddhadeb Dawn Mesenchymal Stem Cell Derived Exosomes - The Potential for Translational Nanomedicine (Hardcover)
Yaoliang Tang, Buddhadeb Dawn
R1,998 Discovery Miles 19 980 Ships in 12 - 17 working days

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas - cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool.

24 Hour Heart Rate Variability Analysis (HRV) in Childhood - Prognostic Significance, Risk Factors & Clinical Applications... 24 Hour Heart Rate Variability Analysis (HRV) in Childhood - Prognostic Significance, Risk Factors & Clinical Applications (Hardcover)
Reiner Buchhorn
R3,772 Discovery Miles 37 720 Ships in 12 - 17 working days

Based upon the hypothesis that prognosis in childhood heart failure depends on autonomic dysfunction, the author introduced a new heart failure model and a medical therapy with beta-blockers in 1996. The author used the analysis of heart rate variability (HRV) in 24 hours Holter ECG's for the understanding of the pathophysiology of childhood heart failure and for objective control of medical therapy. The success of this clinical model was the inspiration of a new approach to mental disease in childhood. In the last decades, an increase of new paediatric problems requiring medical care like eating disorders, behavioural and attention problems has been observed. All these diseases are related to autonomic dysfunction and have a high impact on cardiovascular prognosis. Based upon the hypothesis that behavioural problems are accompanied by changes in the autonomic nervous system, the author performed analysis of HRV in 24 hours Holter ECG's in these patient groups: healthy children with respect to school affiliation; a historical control group from literature published in 1997; attention deficit disorder with and without hyperactivity; anorexia nervosa and obesity. This data was compared to children with an increased cardiovascular risk due to congenital heart disease. In order to analyse the effect of autonomic function on human growth, we measured HRV in children with growth failure. A new HRV Score was established for the comparison of autonomic function in different age groups. The author could demonstrate a decrease of vagal activity in healthy children in children of today and speculate that insufficient vagal maturation may be a reason for an increasing prevalence of mental and cardiovascular disease. Looking for the reason of this vagal shift, caloric over nutrition, omega-3-fatty acid deficiency, high intensity of information and communication technology usage and some environmental toxins reduce HRV in childhood.

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