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From the introduction: The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 years on the physiology of intraocular pressure, ocular blood flow and the relation of these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the author s own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby led to new methods of diagnosis and therapy. "
Patients with cardiac conditions routinely present for noncardiac surgeries, requiring special protocols for perioperative assessment and management by the anesthesiologist. Essentials of Cardiac Anesthesia for Noncardiac Surgery: A Companion to Kaplan's Cardiac Anesthesia provides current, easily accessible information in this complex area, ideal for general anesthesiologists and non-cardiac subspecialists. From preoperative assessment through postoperative care, this practical reference covers all perioperative approaches to today's patients with cardiac conditions. Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment - all from the anesthesiologist's perspective. Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The Angiography pocketcard Set contains a review of important principles used in the administration of angiography and percutaneous coronary intervention (PCI). Content includes the following: Recommendations for selecting appropriate viewing angles for coronary visualization Indications, contraindications and risks of cardiac catheterization and angiography Preprocedural assessment and pretreatment in cardiac catheterization Coronary lesion classification and associated PCI success rates Hemodynamic normal values, waveforms, and formulas Catheter descriptions, TIMI score, and other useful information This pocketcard is intended for interventional cardiologists and other healthcare personnel working with the administration of angiography and PCI in patients with coronary artery disease.
This book presents techniques necessary to predict cardiac arrhythmias, long before they occur, based on minimal ECG data. The authors describe the key information needed for automated ECG signal processing, including ECG signal pre-processing, feature extraction and classification. The adaptive and novel ECG processing techniques introduced in this book are highly effective and suitable for real-time implementation on ASICs.
In 1910, Dr. James B. Herrick published Western medical literature's first description of a person with sickle cell disease. Soon, other physicians reported patients with similar symptoms and confirmed the characteristic feature of the disease: elongated red blood cells. In 1922, the peculiar shape of the cells inspired the official name for the disorder. Within 30 years, scientists had learned about the cause of sickle cell disease - an abnormal form of hemoglobin. ""Sickle Cell Disease"" explores the scientific discoveries that led to an understanding of the genetic basis of the disease, explaining how a single mutation in hemoglobin multiplies into the many symptoms of sickle cell disease. Also investigated are treatments that help individuals manage sickle cell disease symptoms, and how gene therapy and stem cell therapy may one day lead to a cure for the disease.
The heart and lung are intricately linked. When the heart is affected by disease, the lungs will often show some related pathological or clinical conditions and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail. The left ventricle in combination with the other structures in the "left heart" pumps blood throughout the body. The right ventricle (and structures of the "right heart") pumps blood to the lungs where it is oxygenated and returned to the left heart for distribution. In normal circumstances, the right heart pumps blood into the lungs without any resistance. The lungs usually have minimal pressure and the right heart easily pumps blood through. However when there is lung disease present, like emphysema, chronic obstructive lung disease (COPD) or pulmonary hypertension- the small blood vessels become very stiff and rigid. The right ventricle is no longer able to push blood into the lungs and eventually fails. This is known as pulmonary heart disease. Pulmonary heart disease is also known as right heart failure or cor pulmonale. The chief cause of right heart failure is the increase in blood pressure in the lungs (pulmonary artery).
Education in Heart is designed to cover the core subjects for a
continuing medical education programme in cardiology. This popular
series is now collected in book form, creating a comprehensive
update for cardiologists in key topical areas. Every peer reviewed
contribution has been commissioned from a leading international
specialist, to give a concise, yet authoritative overview. Chapters
are enhanced with full colour illustration and useful summaries,
and additional references and ongoing correspondence can be
accessed via the Heart website
Fundamentals of Cardiac Pacing was just honored with 4 Stars from Doody's Book Review! An introductory guide to cardiac pacing, Fundamentals of Cardiac Pacing covers the key topics that residents, fellows, nurses, and other clinical personnel must be familiar with in order to care for the growing number of patients with cardiac pacemakers. This concise and clearly written handbook covers all dimensions of cardiac pacing including indications, technology, implantation techniques, programming, diagnostics, and follow-up as well as evidence-based guidelines for pacemaker implantation, avoidance of complications, and patient preparedness. This is a straightforward, complete and essential guide to the long-term care of patients with cardiac pacemakers, and is the perfect resource for any health care professional.
Echocardiography is one of the most useful and powerful diagnostic tools in the assessment of cardiac function. It remains a rapidly expanding modality, with new techniques constantly developing and maturing. Building on the success of the original work, the second edition of Making Sense of Echocardiography: A Hands-on Guide provides a timely, accessible overview for those learning echocardiography for the first time as well as an accessible handbook that experienced sonographers can refer to throughout their careers. The strong clinical focus and concentration on real-life scenarios make this book especially relevant in day-to-day practice. New chapters in this edition discuss myocardial mechanics and speckle tracking and 3D echo. The book also contains significantly expanded and updated material on: Contrast echocardiography Tissue Doppler imaging Intravascular ultrasound and epicardial echocardiography The left ventricle and its systolic function Left ventricular diastolic function The left atrium Supplying the latest guidelines and evidence-based clinical advice, this edition is also supplemented with new illustrations and an updated website. Fully updated key references for further reading are provided for each chapter. This accessible yet comprehensive text will ensure readers are up to date on the essentials in the field and can confidently integrate new procedures into their everyday practice.
"As I walked away with my refreshments, I felt something peculiar. It was so strange it stopped me mid-step. I was forty-five years old, and I had felt many things, but never before this particular feeling: I felt a click deep inside. The image the sensation produced in my mind was of a BB, a small round piece of copper-colored lead, falling into a socket. It was a very clear image. A BB is tiny, but the one I imagined felt infinitesimal, microscopic. Yet I felt it, a click, metal on metal-like an expensive, microscopic gear had slipped, some exquisite piece of machinery falling out of alignment. Some medieval example of craftsmanship, a gyroscope, something intricate, needing fine balance. The feeling, the event, was located in my chest, below my left breast. It was thoroughly interior, as if a signal had been sent and registered, what those giant satellite dishes are poised waiting for, a transmission from deep space." - from Chapter 1That was October 26, 1991, in what became a singularly awful day in the life of William O'Rourke. Minutes later, at the beginning of a Notre Dame football game, he began to suffer his heart attack. O'Rourke's account of that day, and everything that followed, is personal, informative, humorous, and highly literate. With its extended description of what an MI feels like and how people around the patient react, his memoir provides a bedside view of his experience and all of the emotions-both extraordinary and quotidian-that accompanied it.What is startling is how that momentous event, the heart attack, divides life irretrievably into a "before" and "after." Gone are the assumptions of what is safe and healthy; replacing them is a newly-forged relation of mind and body, a treacherous one which breeds a physical paranoia that only lessens after months. O'Rourke vividly describes the extreme pain of the attack, the forced inactivity of recuperation, and the melancholy of embracing life anew while accepting a heightened awareness of mortality. He knows his luck in having supportive family and friends, and uses his time away from normal routine to examine his family history for likely genetic proclivities for heart disease.Through his description of his experience-from MI, to angioplasty, to cardiac catheterization to, fourteen years later, a quintuple bypass and a second round of cardio-rehabilitation-he asks us to change behaviors we can affect and pay attention to our health. It does, after all, come down to this: "Here's to life."Enriched with a medical glossary and selected bibliography, this is a helpful compendium for other recuperating patients and their families, or anyone concerned about heart disease, or interested in memoir.
Grasp the electrocardiography basics and identify arrhythmias accurately, with the freshly updated ECG Workout, 7th Edition . Fully addressing the most common arrhythmias, this clearly worded text will take you step-by-step through expert ECG tracing interpretation methods, including differentiating among rhythm groups, equipment use, and management protocols. This is the go-to ECG guide for both student training and professional review-perfect for physicians, nurses, medical and nursing students, paramedics, emergency medical technicians, telemetry technicians, and related practitioners. Get a strong grounding in accurate ECG readings with . . . NEW pull-out arrhythmia summary cards help you interpret end-of-chapter practice strips NEW and updated advanced cardiac life support (ACLS) guidelines incorporated in each arrhythmia chapter NEW and updated figures, boxes, tables, and additional practice strips Updated coverage of all ECG concepts and skills, including: Illustrated anatomy and physiology of the heart Electrical basis of electrocardiology Arrhythmia chapters: sinus, atrial, junctional and AV blocks, ventricular and bundle-branch block rhythms-examples, causes, clinical treatments, and practice strips Step-by-step direction on interpreting rhythm strips Components of the ECG tracing: waveforms, intervals, segments, complexes, and waveform identification Discussion of cardiac monitors, lead systems, lead placement, ECG artifacts, and troubleshooting monitor problems Methods for precise rate calculation Discussion of cardiac pacemakers: types, indications, function, pacemaker terminology, malfunctions, and pacemaker analysis, with practice tracings ECG conversion table ensures precise heart rate calculation with plastic pocket version inside back cover Skillbuilder practice strips -more than 600 life-size ECG tracings: End-of-chapter strips from actual patients, with 3-second indicators for rapid-rate calculation, and answers at back of book A mix of arrhythmias to help you distinguish among types Posttest with mix of more than 100 waveform rhythm strips, for student testing or self-evaluation
This book provides an up-to-date, systematic review of all facets of emergency radiology in patients with chest trauma or pain with the aim of equipping the reader with a detailed knowledge of the various radiological patterns, which is essential in order to make a prompt diagnosis under circumstances when time is of critical importance. To this end, the indications, value, and results of the various emergency imaging modalities, including sonography and interventional radiology, are described and illustrated in the full range of blunt chest injuries and nontraumatic chest emergencies. Technological aspects, protocols tailored to the mechanism of injury, and post-processing techniques are also extensively covered. Emergency Radiology of the Chest and Cardiovascular System will be of value to general and interventional radiologists, radiology residents, radiology technicians, and all physicians and surgeons who work in emergency care.
Understanding Hypertension, Second Edition is a popular chart featuring artwork from Anatomical Chart Company that helps to explain hypertension, its causes and effects, and treatment. Topics features and defined: Hypertension Blood pressure Types of Hypertension Effects in blood vessels, including vascular hypertrophy and atherosclerosis Blood flow in the heart Effects in the heart, including left ventricular hypertrophy Effects in the brain Effects in the eye Effects in the kidneys Healthy life style changes Drug treatments Leonard S. Lilly, MD, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 20" x 26" heavy paper laminated with grommets at top corners ISBN 9781496369819
This is a book for any care provider - from advanced students and nurses to residents and even specialists - who needs to master the interpretation of ECGs, especially while "on the spot" at the point of care. This easy-to-use, visual guide takes a novel approach, foregrounding the visual clues or "keys" that readers can learn to recognize in ECGs and thus make rapid decisions about next steps at the point of care. The comparatively minimal text focuses on "must-know" information about the underlying cause of ECG abnormalities. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
Prepare yourself for success with this unique cardiology primer which distils the core information you require and presents it in an easily digestible format. * Provides cardiologists with a thorough and up-to-date review of cardiology, from pathophysiology to practical, evidence-based management * Ably synthesizes pathophysiology fundamentals and evidence based approaches to prepare a physician for a subspecialty career in cardiology * Clinical chapters cover coronary artery disease, heart failure, arrhythmias, valvular disorders, pericardial disorders, and peripheral arterial disease * Practical chapters address ECG, coronary angiography, catheterization techniques, ecnocardiography, hemodynamics, and electrophysiological testing * Includes over 650 figures, key notes boxes, references for further study, and coverage of clinical trials * Review questions at the end of each chapter help clarify topics and can be used for Board preparation - over 375 questions in all!
As the nature of medical care becomes more preventive, rather than crisis-driven, the diagnosis and treatment of peripheral vascular disease become more relevant to everyday practice. Approximately two million patients in Europe and the United States suffer from critical limb ischemia. Nearly half of these sufferers will require major amputation within one year after the onset of limb ischemia. In addition, in the United States, prevalence of abdominal aortic aneurysm is quite significant. In 2002, 200,000 abdominal aortic aneurysms were diagnosed, adding to the estimated one and half million patients who currently experience this disease. In fact, 10% of men over 80 years of age, have significant abdominal aortic aneurysms. Furthermore, 20% of the patients who undergo coronary intervention have renal artery stenosis, with as many as 50% of those patients having critical stenosis. Embolic protection traditionally used for carotid intervention is now being applied in both femoral and renal applications. The field has also seen an explosion in the ability to screen patients with peripheral vascular disease, knowing that this is a potent predictor of comorbid cardiovascular disease.
The second edition of the highly successful "Textbook of Peripheral Vascular Interventions" discusses therapies that can make a real difference in the lives of patients. Effective, less invasive approaches to therapies for critical limb ischemia, chronic total occlusions, as well as therapies for some subsets, are discussed by an illustrious team of international multispeciality contributors.
"Textbook of Peripheral Vascular Interventions, Second Edition," is not only for cardiologists, but also forradiologists, endovascular surgeons, vascular surgeons, and cardiovascular surgeons becoming involved in these therapies.
In this book, an international group of investigators from a broad array of clinical and basic disciplines present the ideas and concepts in the foreground of cerebrovascular disease. Included in their discussion are perspectives on topics that continue to guide current investigations, such as white matter injury, newer imaging approaches, delayed neuronal death, and recovery after stroke, as well as continuing disagreements on the value of heparin or MRI endpoints in the management of stroke patients. Further topics include a proposal for a major multicenter re-study of the utility of extracranial-intracranial bypass surgery in light of additional diagnostic information available through PET scanning; examination of how processes such as apoptosis, inflammation, free radicals, poly (ADP-ribose) polymerase activation, and alterations in glutamate receptor function contribute to the pathogenesis of ischemic brain injury; and finally an exploration of how estrogens or cholesterol-lowering agents might be used therapeutically.
This book describes the most popular topics concerning adult congenital heart disease (ACHD), especially focusing on indications and re-intervention procedures for some major ACHDs. Thanks to advances in medical and surgical therapy for congenital heart disease over the last half century, many patients who underwent surgical correction reached adulthood. However, as can be seen from the explosive increase in the number of ACHD patients, postoperative residua and sequelae have also become apparent. The purpose of this book is to highlight complicated problems in connection with ACHD, including its present status, as well as methods for its management including medical and surgical treatment. The content primarily focuses on two areas - general information for cardiologists, and information on re-intervention for interventionists and cardiac surgeons -, setting it apart from the majority of books on congenital heart disease.
This second edition of the book on Store-operated Ca2+ Entry Pathways has been updated with the newest discoveries that emerged in the field within the last five years. The crystal structure of the Ca2+ signaling core complex is described which adds to a new understanding of the molecular interactions involved. Each chapter has been revised and extended. The book retains its interdisciplinary approach and supplies biochemists, cell biologists and biophysicists as well as clinicians in immunology, neurology and cardiology with valuable information on Ca2+ signaling mechanisms, functions, dysfunctions and their consequences.
Written by an expert team of cardiologists, radiologists, and basic scientists, this third edition of Cardiovascular Magnetic Resonance continues to bridge the divide among specialty areas in with cohesive presentation of this complex and fast-changing field. Offering comprehensive coverage of CMR and the latest cardiology applications, this practical reference enhances the understanding of cardiac physiology and the interpretation and diagnosis of cardiovascular disease. This is an ideal resource for cardiologists, cardiovascular and general radiologists, and anyone who needs up-to-date information on CMR's uses, benefits, and limitations in cardiovascular care. Provides state-of-the-art coverage of CMR technologies and guidelines, including basic principles, imaging techniques, ischemic heart disease, right ventricular and congenital heart disease, vascular and pericardium conditions, and functional cardiovascular disease. Includes new chapters on non-cardiac pathology, pacemaker safety, economics of CMR, and guidelines as well as new coverage of myocarditis and its diagnosis and assessment of prognosis by cardiovascular magnetic resonance, and the use of PET/CMR imaging of the heart, especially in sarcoidosis. Features more than 1,100 high-quality images representing today's CMR imaging. Covers T1, T2 and ECV mapping, as well as T2* imaging in iron overload, which has been shown to save lives in patients with thalassaemia major. Discusses the cost-effectiveness of CMR. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This practical text aims to demystify electrophysiology for the cardia c trainee and details the management of different types of arrhythmias, one of the most common cardiac conditions.
This book represents the first comprehensive, gold standard reader on research integrity in the biomedical sciences. Now more than ever, the responsible conduct of research (RCR) has become critically important as new technologies affect research practices in both positive and negative ways. Since learning to do science and practicing it brings researchers into contact with a vast array of ethical issues, it is critical to know the standards and how they are evolving. Indeed, research integrity requires scientists at all levels to operate ethically in a system that supports ethical practice. This unique, foundational text covers all the relevant areas -- subject protection, research misconduct and conflict of interest as well as newly quantified concerns about research bias and non-reproducibility, as well as other unique issues. Developed by renowned experts, this compelling title discusses the full range of practices and policies that should support research that is honestly produced and disseminated. It also specifically incorporates topics noted by the National Institutes of Health as essential and required for training in RCR. Getting to Good - Research Integrity in the Biomedical Sciences is a major contribution to the literature on bioethics and will serve as an invaluable resource for all researchers, students, administrators and professionals interested in research ethics and integrity.
Here's a user-friendly, readable introduction to the study of electrocardiography. It guides you in capturing and interpreting ECGs, with an eye towards clinical correlation for easy application to your practice. New in this edition are increased content on pediatric ECGs, implantable cardiodefibrillators, and pacemakers. Comprehensively and expertly describes how to capture and interpret all normal and abnormal ECG findings in adults and children. Features the expertise of internationally recognized authorities on electrocardiography, for advanced assistance in mastering the subtle but critical nuances of this complex diagnostic modality. Features new chapters on pediatric electrocardiography that explore rhythm problems associated with pediatric obesity, heart failure, and athletic activity. Presents a new chapter on recording and interpreting heart rhythms in patients with pacemakers. Includes new material on interpreting ECG findings associated with implantable cardioverter-defibrillators. Provides fully updated coverage on the increased importance of ECGs in stress testing.
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