Cardiac MR is explored in this important issue in MRI Clinics of North America. Articles will include: MR physics in practice; Ventricular mechanics: Techniques and applications; MR safety issues particular to women; Novel MR applications for evaluation of pericardial diseases; 4D flow applications for aortic diseases; T1 mapping: technique and applications; ARVD: An updated imaging approach; Imaging the metabolic syndrome; Coronary MRA: how to optimize image quality; Prognostic role of MRI in nonischemic myocardial disease; MRI for valvular imaging; MRI for adult congenital heart disease assessment; Cardiac MRI applications for cancer patients; Applications of PET-MRI for cardiovascular disease; Rings and slings, and more.

Trigeminocardiac Reflex is a comprehensive tutorial reference to the science, diagnosis, and possible treatment of the trigeminocardiac reflex (TCR) that is usually initiated when the trigeminal nerve is disturbed during intercranial surgery. Since first reported in 1999 by co-Editor Bernhard Schaller, the research focused on TCR is expanding. While its instance is rare, new discoveries are not only increasing diagnosis, but also providing more effective treatment protocols. This text is ideal as a reference for clinical and research neurologists, as a general introduction for clinical presentation, and as a foundation for new research.

The standard electrocardiogram (ECG) is an indispensable, safe, and inexpensive test to assess dogs and cats with heart disease. This bestselling user-friendly book discusses the principles of electrocardiography, then systematically explores the evaluation of the ECG, including determination of heart rate, measurement of intervals, derivation of mean electrical axis, and criteria for atrial/ventricular enlargement or hypertrophy. At the core of this book is an extensive series of ECG cases for the reader to work through: practice makes perfect. New to this edition: Instructions on how to obtain an ECG A new chapter on the treatment of the most common clinically important ECG arrhythmias A second new chapter on 24-hour ECG (Holter) monitoring A handy one-page reference guide of important ECG values and diagrams, which can be downloaded from the book's webpage for easy reference 15 new ECG cases have been added to the original 46 cases, with a selection of advanced cases geared toward readers craving more challenging topics such as electrical cardioversion and pacemaker function. This updated edition will further aid veterinarians in their quest to better interpret the ECG. It provides information in an appealing, accessible, and easy to use format that fits with the busy lives of veterinary practitioners.

This book highlights recent advances in beta blockers research. Beta blockers have been used for the treatment of several clinical conditions and it is of paramount importance to understand their role and applications. Chapters of the book were written by experts in the fields of vascular disease, plastic surgery, cardiovascular medicine, pharmaceutical medicine and physiology from various countries such as the United States, the United Kingdom, Brazil, Japan and New Zealand. Clinical topics on recent advances in beat-blockers research covered in this book include the clinical effectiveness of beta-blockers in patients with peripheral arterial disease, abdominal aortic aneurysm, heart failure, acute coronary syndrome, pulmonary hypertension, object memory recognition, portal hypertension and infantile haemangioma. These chapters were written by authors who are experts in their fields and by researchers who are most up-to-date in the recent literature on advances in beta-blockers research.

Cardiovascular disease refers to the class of diseases that involve the heart or blood vessels. While the term technically refers to any disease that affects the cardiovascular system, it is usually used to refer to those related to atherosclerosis. Chronic heart failure (CHF) has emerged as a major worldwide epidemic. This book gathers the latest research in cardiovascular disease with a focus on such topics as cardiac thrombus quantification in clinical practice; aspartate protease cathepsin D in liver and heart injury, pathophysiology and therapy; hypertension, arterial stiffness and cardiovascular outcomes; fractional flow reserve is an essential measure for the management of patients with stable coronary artery disease; arterial stiffness and vascular calcifications in chronic kidney disease patients; the clinical application of coronary flow velocity reserve by transthoracic Doppler echocardiography; management of right heart failure; short QT syndrome; new horizons in preventing graft arterial disease; and associations between cathepsin B and inflammation markers in elderly males and females.

Pulmonary arterial hypertension (PAH) is a progressive, fatal syndrome characterised by increased vascular resistance that leads to right-ventricular hypertrophy and heart failure, eventually leading to death. The chapters of this book describe the molecular mechanisms and cellular events regulating vascular remodelling in PAH; the various animal models and drugs currently being used in various laboratories to study mechanisms leading to pulmonary arterial hypertension; and nifedipine, its pharmacology and its role in the management of pulmonary hypertension and some of the drawbacks concerning its use. The authors also discuss drug delivery systems that can lead to different crystallisation forms of the immobilised drug which can lead to better solubility and bioavailability.

It is well known that cardiovascular events occur more frequently in the morning as blood pressure (BP) levels have been shown to increase during the period from night to early morning. In recent years, clinical research using ambulatory blood pressure monitoring (ABPM) or home BP monitoring has clarified that morning BP and BP surge are more closely related to the cardiovascular risk than clinical BP. This practical manual from field leading expert, Dr. Kazuomi Kario, reviews recent evidence on "morning" and "nocturnal" hypertension and the IT technologies physicians can use to support patients in home monitoring BP. Guidance on management via antihypertensive drugs is also discussed and with the aim of promoting "perfect 24 hour BP control".

Cardiovascular disease refers to the class of diseases that involve the heart or blood vessels. While the term technically refers to any disease that affects the cardiovascular system, it is usually used to refer to those related to atherosclerosis. Chronic heart failure (CHF) has emerged as a major worldwide epidemic. This book gathers the latest research in cardiovascular disease with a focus on such topics as genetic risk factors for abdominal aortic aneurysms; blood pressure monitoring in biological time structures seasonal variations in ordinary living with perioperative case and salt restriction/weight reduction; genetics and perinatal milieus affecting saline preference in hypertensive rats; the influence of apolipoproteins in cardiovascular diseases; and novel effects of macrolide on MMP-related cardiovascular remodeling.

This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progress to diabetes and heart disease. The book further focuses on glucose intake and utilization in diabetes, including coverage of diabetes in the development and pathology of cardiovascular disease, risks and epidemiology of cardiovascular problems promoted by diabetes, macrovascular effects and their safety in therapy of diabetics, beta cell biology and therapy of diabetes, and nutrition to modulate diabetes.

Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure's breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students.

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States and most westernized nations. Both CVDs and their risk factors confer substantial risk for stroke and dementia, but are also associated with more subtle changes in brain structure and function and cognitive performance prior to such devastating clinical outcomes. It has been suggested that there exists a continuum of brain abnormalities and cognitive difficulties associated with increasingly severe manifestations of cardiovascular risk factors and diseases that precede vascular cognitive impairment and may ultimately culminate in stroke or dementia. This second edition examines the relations of a host of behavioral and biomedical risk factors, in addition to subclinical and clinical CVDs, to brain and cognitive function. Associations with dementia and pre-dementia cognitive performance are reported, described, and discussed with a focus on underlying brain mechanisms. Future research agendas are suggested, and clinical implications are considered. The volume is a resource for professionals and students in neuropsychology, behavioral medicine, neurology, cardiology, cardiovascular and behavioral epidemiology, gerontology, geriatric medicine, nursing, adult developmental psychology, and for other physicians and health care professionals who work with patients with, or at risk for, CVDs.

This issue of Interventional Cardiology Clinics, edited by Susheel K. Kodali, is devoted to Transcatheter Aortic Valve Replacement. Dr. Kodali assembled a group of expert contributors to review the following topics: Risk Assessment in Patient Selection for Transcatheter Aortic Valve Replacement; Management of Coronary Disease in the Era of Transcatheter Aortic Valve Replacement: Comprehensive Review of the Literature; Imaging the Aortic Annulus with Multi-Detector Computed Tomography and 3-Dimensional Transesophageal Echocardiography; The Role of Preoperative and Intraoperative Imaging in Guiding Transcatheter Aortic Valve Replacement; Assessment of Paravalvular Regurgitation Following Transcatheter Aortic Valve Replacement; Impact and Management of Paravalvular Regurgitation After Transcatheter Aortic Valve Replacement; Neurologic Events After Transcatheter Aortic Valve Replacement; Nontransfemoral Approaches to Transcatheter Aortic Valve Replacement; and Valve-in-Valve Therapy for Failed Surgical Bioprosthetic Valves: Clinical Results and Procedural Guidance.

"Cardiology Core Curriculum" fills the gap between the preclinical pathophysiology texts and specialist volumes aimed at cardiologists. It covers clinical cardiology for medical students, cardiology trainees and non specialists. Based on a successful course run by the Cardiology Division, University of Texas at Southwestern Medical Center in Dallas, the problem oriented approach is in line with current medical school teaching. Case histories with self testing questions reinforce the learning and are ideal for exam preparation.

Regenerative therapy has rapidly developed as one of the most promising treatments for patients suffering from severe heart failure. Autologous bone marrow-derived cells and cardiac stem cells have been clinically applied for cell injection therapy for heart failure. As a next-generation therapy, tissue-engineered myocardial-patch transplantation has also been started clinically. As further advanced therapy, several researchers have started to fabricate three-dimensional beating myocardial tissues. One of the main problems in myocardial tissue engineering is neovascularization within the tissues during scale-up. Several innovative technologies have been developed to overcome the vascularization problem. This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. With respect to myocardial cell source, it focuses on cardiac cells differentiated from embryonic stem and induced pluripotent stem cells. It describes the remarkable results obtained in the past and the present to control neovascularization and presents the future challenges in myocardial tissue engineering research.

The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity.

"Erectile Dysfunction as a Cardiovascular Impairment" organizes and summarizes the many aspects of biology and metabolism in cardiovascular and sexual function. Coverage includes how blood vessels are discovered to work, their role in hypertension, atherosclerosis, type-2 diabetes, oxidative stress, metabolic syndrome, and erectile dysfunction.
Unifies medical disorders linked to cardiovascular and heart disease as endothelium impairment, to which
vasculogenic erectile dysfunction is now added and given equal rank for the first timePresents hypertension, atherosclerosis, metabolic syndrome, and erectile dysfunction as symptoms of diseaseOffers clinical research on vasculogenic erectile dysfunction predicting onset and severity of heart disease.

Combining the research and study of integrative Chinese and Western Medicine, Integrative "Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective" presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners.

This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research.
Integrates Western and Chinese medicine for a realistic scope of cardiology treatmentEstablishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology"Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical useOffers a reference section that lists the latest in published studiesPresents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents

Each year, more than one million cardiac implantable electronic devices (CIEDs) are implanted worldwide for cardiac rhythm management, and chest x-ray is a common initial diagnostic method for evaluation of cardiac and pulmonary diseases. Radiographic Atlas of Cardiac Implantable Electronic Devices provides comprehensive, step-by-step coverage that is invaluable for cardiac electrophysiologists and other clinicians who encounter patients with these devices. An outstanding editorial team of Drs. Majid Haghjoo, Farzad Kamali, and Amirfarjam Fazelifar, all of the Rajaie Cardiovascular Medical & Research Center in Tehran, Iran, provide expert guidance in recognizing the typical features of these devices and detecting related complications in post-implant patients. Offers a stepwise and user-friendly approach to diagnostic evaluation of chest x-rays in patients with cardiac implantable electronic devices (CIEDs). Includes chest x-rays of common and new CIEDs, including permanent pacemakers, implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy devices (CRT pacemakers and defibrillators, novel CIEDs (SICDs and wireless pacemakers), and implantable cardiac monitors (ICMs). Differentiates among different types of CIEDs, their proper position on x-rays, and common complications. Features 85 high-quality radiographic images.

Learn about: arteries, arterioles, capillaries, venules, veins, atria, ventricles, superior and inferior vena cava, pulmonary artery and vein, aorta, tricuspid and mitral valve, sinoatrial node, atrioventricular node, and purkinje fibers. Understand each of these terms and where they are located in this color-packed guide to the heart For all ages to enjoy.

This volume of the esteemed "Progress in Molecular Biology and Translational Science" series focuses on cutting-edge research related to the genetics of cardiovascular disease. Written by top experts in the field, this volume covers a range of topics, including:

Genetic models of atherosclerosis

MicroRNAs in cardiovascular disease

The role of the transcription factor KLF2 in vascular development and disease

Zebrafish as models of cardiovascular disease and hematopoietic development

"Progress in Molecular Biology and Translational Science" provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.

Key features: The authors are all experts in the fieldThe reviews are in themselves comprehensiveEach topic has the potential to lead to advances in therapy of cardiovascular disease

"The HDL Handbook: Biological Functions to Clinical Implications" brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication usefulbecause the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.
Provides bench-to-bedside coverage of HDL with thorough coverage of basic science, genetics, epidemiology, and treatment Presents a complete update with six new chapters on the latest advances in HDL cholesterol research with international perspective New chapters on proteomics, clinical impact of LCAT in HDL metabolism, and an in-depth discussion of potential targets to modify HDL provide a translational reference for clinicians"

Cardio-Hepatology: Connections Between Hepatic and Cardiovascular Disease provides a direct relationship between the cardiac and hepatic pathologies providing the link between the heart and liver and showing how liver diseases predispose to impairment in heart functioning and vice versa. Considering the growing number of patients living (and living longer) with heart failure and/or congenital heart disease, it is important to know when and how to test for liver disease in this population, how to interpret abnormal test results, and what management is appropriate. Coverage includes what should be done for patients to limit, avoid, or postpone the impairment in the liver functioning induced by heart diseases and the impairment in the heart functioning induced by liver diseases, on the basis of scientific-exposed evidence and pathophysiology knowledge. This comprehensive, extended review of the medical literature is perfect for researchers interested in the connection between cardiology and hepatology as well as clinicians making therapeutic decisions for patients suffering from heart or liver chronic diseases.

"Electrocardiography of Laboratory Animals" is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. "Electrocardiography of Laboratory Animals" will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electrocardiography of various species of animals used in research.
Covers safety electrocardiography of large laboratory animalsOffers comprehensive analysis of ECGs for practical laboratory useIncludes a self-evaluation section for testing of ECG reading and analysis

Nothing is more perplexing to the clinician new to device therapy than having to deal with cardiac electrocardiograms from a device patient. Pacemakers and other implantable cardiac rhythm management devices leave their "imprint" on ECGs and can significantly change what clinicians see - or expect to see. Evaluating paced ECGs can be challenging, yet nowhere is it taught in any sort of comprehensive manner.

Designed specifically for clinicians new to device therapy, "The Nuts and Bolts of Interpreting Paced ECGs and EGMs" offers practical, reliable and objective information on paced cardiac electrograms. Written in a lively, intelligent and easy to navigate style, emphasizing real-life clinical practice and practical tips, this book includes illustrated paced ECGs by skilled artists to help minimize "fuzzy" lines and emphasize key points. Each chapter concludes with a checklist of key points from each subject ("Nuts and Bolts").

Podrid's Real-World ECGs: A Master's Approach to the Art and Practice of Clinical ECG Interpretation Podrid's Real-World ECGs combines traditional case-based workbooks with a versatile Web-based program to offer students, health care professionals, and physicians an indispensable resource for developing and honing the technical skills and systematic approach needed to interpret ECGs with confidence. ECGs from real patient cases offer a complete and in-depth learning experience by focusing on fundamental electrophysiologic properties and clinical concepts as well as detailed discussion of important diagnostic findings and relevant management decisions. Six comprehensive volumes encompass more than 600 individual case studies - plus an online repository of hundreds more interactive case studies (www.realworldECGs.com) - that include feedback and discussion about the important waveforms and clinical decision-making involved. From an introductory volume that outlines the approaches and tools utilized in the analysis of all ECGs to subsequent volumes covering particular disease entities for which the ECG is useful, readers will take away the in-depth knowledge needed to successfully interpret the spectrum of routine to challenging ECGs they will encounter in their own clinical practice. Volume 1: The Basics outlines the approaches and tools utilized in the analysis of all ECGs, including the identification of important waveforms and subtle abnormalities. This introductory volume lays the foundation for a true understanding of vital ECG principles, including normal activation of the atria and ventricles, the standard lead system, normal waveforms and intervals, and components of a normal ECG recording.