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This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.
The third edition of Hypertension: A Companion to Braunwald's Heart Disease, by Drs. George L. Bakris and Matthew Sorrentino, focuses on every aspect of managing and treating patients who suffer from hypertensive disorders. Designed for cardiologists, endocrinologists and nephrologists alike, this expansive, in-depth review boasts expert guidance from contributors worldwide, keeping you abreast of the latest developments from basic science to clinical trials and guidelines. Hypertension also includes an Expert Consult eBook updated with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald. Features expert guidance from worldwide contributors in cardiology, endocrinology, neurology and nephrology. Covers behavior management as an integral part of treatment plans for hypertensives and pre-hypertensives. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, videos, and references from the book on a variety of devices. Covers new developments in epidemiology, pathophysiology, immunology, clinical findings, laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, prognosis, and management. Includes chapters on hot topics such as hypertension as an immune disease; sleep disorders including sleep apnea, a major cause of hypertension; a novel chapter on environmental pollution and its contribution to endothelial dysfunction, and more! Equips you with the most recent guidelines from the major societies. Updates sourced from the main Braunwald's Heart Disease text. Highlights new combination drug therapies and the management of chronic complications of hypertension.
Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with Hemodynamics and Cardiology, 3rd Edition. A new editorial team and a completely redesigned volume with state-of-the-art chapters on neonatal hemodynamics. New chapters on the role of delayed cord clamping/cord milking, the relationship between neonatal transition and brain injury, the hemodynamics of the asphyxiated neonate, the hemodynamic impact of therapeutic hypothermia, and practical physiology-based approaches to the diagnosis and treatment of neonatal hypotension, PPHN and PDA. A new section discusses comprehensive real-time monitoring of neonatal hemodynamics, and its role in the establishment of precision medicine in neonatology and the prediction of neonatal sepsis using mathematical modelling of heart rate variability. Expanded sections review the clinical application of the tools available for bedside monitoring of systemic and organ blood flow and oxygen delivery and the approaches to the pathophysiology-based treatment of neonatal shock and outcomes. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. Purchase each volume individually, or get the entire 7-volume set, which includes online access that allows you to search across all titles! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology
A concise and practical tool for learning the basic concepts of cardiac electrophysiology, including the diagnosis and management of cardiac arrhythmias, and the indications for patient referral. Clinically oriented, practical and a useful resource for: Allied health professionals in the lab and in the clinic Fellows The general physician who needs to know the technical aspects of electrophysiology Anyone on the front line dealing with patients that present with cardiac problems
This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care.
This monograph on the adult with tetralogy of Fallot (TOF) is the first of a series dedicated to common topics in adult congenital cardiac disease (CHD). Published under the auspices of the International Society of Adult Congenital Cardiac Disease (ISACCD), the monograph provides comprehensive, timely review of the adult with TOF, the most common form of cyanotic CHD. The 6 chapters of the monograph, written by international authorities in the field, contain background information and current data on the major clinical problems facing adults with TOF.Patients born with TOF, although 'fixed,' are not 'cured'. Improving survival and quality of life for this ever-increasing adult population will continue to challenge the current and future generations of cardiologists. This monograph is intended as both an introduction to the subject and a timely, comprehensive review, more extensive than a review article and more up-to-date than a textbook. As such, this monograph should be of interest to the internist and the cardiologist who find themselves encountering adults with congenital heart defects with increasing frequency in their practice. Key references provided at the end of each chapter present the relevant literature, allowing for further reading.
"A Doody's Core Title 2012"
New applications of echocardiography, nuclear magnetic resonance, cardiovascular magnetic resonance, and cardiac computed tomography are rapidly developing and it is imperative that trainees and practitioners alike remain up to date in the latest developments. It is becoming increasingly difficult to remain abreast of these advances in each individual modality and thus it is no longer practical to focus on one at a time. In addition, training guidelines are changing and multimodality training has become the norm.
"Multimodality Imaging in Cardiovascular Medicine" presents a clear and in-depth review of the available technologies and evidence supporting their appropriate clinical applications. Hundreds of outstanding images are included to support and augment the discussions from the leading experts in each modality. For maximum clinical value, rather than organize the content by imaging modality, the book is organized by disease so that the reader can utilize the book in real-time problem solving and decision making in daily clinical practice.
Features of "Multimodality Imaging in Cardiovascular Medicine" Include More than 350 multimodality imaging examples of cardiovascular pathophysiology Corresponding text places the images into context at the interface with patient care State-of-the-art chapters contributed by the leading imaging experts
This book covers clinical management including diagnosis, localization and physiology, for a number of clinical diseases treated by endocrinologists and surgeons. Following each chapter there is a 3-4 page biographical sketch of the person behind the clinical endocrinopathy, whose name is closely associated with the disease. The field of endocrine surgery is rich in history and this is the first text to bring together in one place the person behind the disease and the pioneers of the field. The text covers both the current management of endocrine surgical diseases, and also provides a historical background by highlighting the person in whom these discoveries were named after. Surgical Endocrinopathies is of great value to endocrine surgeons, ENT surgeons, endocrinologists, internal medicine and medical historians.
Patients with cardiac conditions routinely present for noncardiac surgeries, requiring special protocols for perioperative assessment and management by the anesthesiologist. Essentials of Cardiac Anesthesia for Noncardiac Surgery: A Companion to Kaplan's Cardiac Anesthesia provides current, easily accessible information in this complex area, ideal for general anesthesiologists and non-cardiac subspecialists. From preoperative assessment through postoperative care, this practical reference covers all perioperative approaches to today's patients with cardiac conditions. Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment - all from the anesthesiologist's perspective. Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Echocardiography: A Practical Guide for Reporting and Interpretation is a step-by-step guide to clinical echocardiography. This new edition has been extensively revised and includes new international guidelines, grading criteria and normal data. The book presents an up-to-date discussion of echocardiography use in both acute and critical care settings and provides increased guidance for clinical interpretation, including how echocardiography can help inform surgical decisions. In addition, the content has been extended, particularly in the consideration of valve disease and cardiomyopathies. Providing a pragmatic approach to clinical echocardiography, the book also covers examples of conditions requiring urgent clinical advice. It contains a summary of formulae as well as supporting online images and videos.
Deliver safe, accurate care during electrocardiographic monitoring, with the newly updated ECG Interpretation Made Incredibly Easy! Sixth edition. This easy-to-follow, fully illustrated text explains the basics of cardiac physiology, then leads you through recognizing and treating arrhythmias, with step-by-step guidance on current medications, devices, and monitoring equipment. Take advantage of this real-world, expert nursing advice to reinforce your class materials, prepare for the NCLEX or certification exam, and strengthen your ECG interpretation skills. Features: * Coverage of topics including: o ECG fundamentals - cardiac anatomy and physiology; obtaining and interpreting a rhythm strip o Identifying and interpreting arrhythmias - atrial, junctional, ventricular, atrioventricular, and more * Hundreds of photos, illustrations, and diagrams explain key concepts and provide clear direction on vital procedures, including: o The 8-Step Method for interpreting a rhythm strip o Nonpharmacologic and pharmacologic treatments for arrhythmias, including pacemakers, ICDs, and antiarrhythmics o Obtaining and interpreting a 12-lead ECG o Troubleshooting equipment problems * Helpful practice questions and quick guides include: o End-of-book multiple choice Q&A o Sample rhythm strips to help you practice your interpretation skills o A Quick Guide to arrhythmias * Special features: o Ages and stages - Identifies differences in ECGs and pacemaker needs, according to the patient's age o Now I get it - Clear-cut directions for performing complex procedures, such as using an automated external defibrillator o Don't skip this strip - Identifies the arrhythmias that have the most serious consequences o Mixed signals - Insights on solving common problems in ECG monitoring and interpretation o I can't waste time - Key points you need to know for conditions that require quick identification and treatment o Quick quiz - Questions with answers/explanations at end of every chapter, to help you remember vital points
This book covers fully the unique needs of patients in a UK setting. Each high risk group has a chapter dedicated to specific pathophysiological nuances, exercise prescription and exercise delivery. In addition, other influences on exercise including medications, appliances etc. are covered. Each chapter is based on the latest and best evidence.
This book provides an easy-to-use guide, giving cardiologists and other physicians more confidence in training with and understanding cardiac magnetic resonance (CMR) in clinical daily practice. The case-based format promotes step-by-step learning and makes this book a helpful tool for students, residents and trainees in cardiology. An updated, comprehensive review of CMR diagnostic criteria is provided for all clinical cardiovascular applications of CMR in adult patients, from ischemic heart diseases to myocarditis, and from pericardial diseases to tumors, artifacts and incidental findings. CMR is an expanding imaging technique for cardiologists and radiologists alike. Despite several textbooks, manuals and dedicated texts, clinicians may still find it difficult to familiarize themselves with the exam and there are limited formats that provide easy access to the basic information (e.g. physics, specific applications) that are needed for training and clinical interpretation (especially case-based). By describing the basics of physics and methodology in a straightforward manner and providing meaningful clinical examples, this book will help all cardiologists dealing with cardiac imaging as well as doctors in training to quickly and accurately interpret CMR findings in their clinical practice.
The book provides an introduction to CMR imaging that is understandable and focused on the relevant information needed to using CMR imaging in clinical practice. Cardiovascular magnetic resonance (CMR) imaging has become an established imaging modality with an expanding range of clinical indications. While in the past the availability of CMR imaging was limited to a few specialist centres the method is becoming more widely available. Most clinicians therefore need to have a general understanding of the diagnostic information that can be obtained from CMR imaging, the indications for referral as well as contraindications and limitations of the method. For cardiologists and radiologists in particular, CMR imaging will become a routine diagnostic tool and training curricula in Cardiology or Radiology reflect this trend by increasingly demanding training in CMR imaging.
This atlas comprehensively describes the application of computed tomography (CT) and magnetic resonance (MR) imaging in real-world scenarios using 192 illustrative clinical cases. These imaging techniques are revolutionizing the diagnostic and therapeutic approach for cardiovascular patients and are progressively becoming viable sub-specialties among radiologists and cardiologists. Clinical Atlas of Cardiac and Aortic CT and MRI features clinically relevant case-based examples of how CT and MR imaging techniques can be applied to identify the pathological features of a range of acquired and congenital heart diseases. Using more than 1000 high-quality figures of distinctive CT and MR imaging features of most cardiovascular diseases, both acquired and congenital, it therefore provides a valuable resource for both specialist and non-specialist radiology/cardiology practitioners seeking to develop a deep understanding of how to recognize the features of a variety of heart diseases using CT and MR imaging techniques.
Rapid advancements in cardiac electrophysiology require today's health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field. An attractive full-color design features color photos, tables, flow charts, ECGs, and more. All chapters have been significantly revised and updated by global leaders in the field, including 19 new chapters covering both basic and clinical topics. New topics include advances in basic science as well as recent clinical technology, such as leadless pacemakers; catheter ablation as a new class I recommendation for atrial fibrillation after failed medical therapy; current cardiac drugs and techniques; and a new video library covering topics that range from basic mapping (for the researcher) to clinical use (implantations). Each chapter is packed with the latest information necessary for optimal basic research as well as patient care, and additional figures, tables, and videos are readily available online. New editor William G. Stevenson, highly regarded in the EP community, brings a fresh perspective to this award-winning text. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.
Written and edited by today's most-recognized inteventional cardiology thought leaders, this popular guide focuses on key procedures and techniques. Each strategic or tactical move is graded by complexity level and described in a simple, step-by-step approach that includes guidance on how to overcome practical difficulties and navigate particularly challenging clinical scenarios and complications. It offers interventional cardiologists, fellows in interventional cardiology, cath lab nurses and technicians; vascular surgeons and fellows, interventional radiologists: *"Tips and tricks" gathered from the personal experience of over fifty international experts *Clear, practical, step-by-step guidance on the latest procedures and techniques, performing challenging interventions, and managing complications and other difficult situations where evidence may be limited or inconsistent *New coverage of hot topics such as percutaneous aortic valve replacement, renal artery ablation, intracranial interventions, and more
Electrical therapy of the heart has rapidly evolved over recent years with the development of the cardiac implantable defibrillator and the application of the cardiac resynchronization therapy to improve performance of the congestive failed heart. There is an impressive amount of literature produced to assess the efficacy and effectiveness of the electrical therapy. New technology is continuously introduced into the market for the treatment of electrical heart disease with optimized performance and implemented design, with approximately 600,000 new pacemakers implanted each year. Attention of the electrophysiology community has mainly focused on the biomedical aspects of electrical therapy, but the psychological, emotional, social and cognitive aspects of the implantable devices has been largely overlooked. Health-related quality of life (QoL) and, to a lesser extent, psychological disorders, i.e. anxiety and depression, have rarely been assessed as outcomes in clinical trials, and results are pointing towards the impact of the implantable devices on QoL and mental health not being direct but moderated and mediated by several biomedical as well as psychosocial variables. Furthermore, the cognitive effects of the implantable devices have rarely been assessed in empirical studies, although cognitive impairment is largely associated with the heart disorders that require implantation of an electrical device and cognitive benefits are strongly expected from the therapy. The aim of this book is to collect, appraise and condense the results of all empirical studies that have investigated, even marginally, the relationships between the implantable devices and any psychological, emotional, social and cognitive dimension. This book is a cornerstone for all involved in device utilization (physicians, nurses, technicians, industry representatives) that need to understand this topic.
Published in association with the Society for Vascular Surgery (SVS), the newly updated edition of Rich's Vascular Trauma draws on civilian and military authorities from around the world to offer comprehensive and up-to-date coverage of the management of vascular injury. Anatomic patterns of vascular trauma including extremity, torso and cervical injury are reviewed in detail, including the latest techniques to manage non-compressible torso hemorrhage. You'll have access to all of the current innovations across the broad spectrum of vascular trauma, presented in a well-organized fashion that allows you to quickly hone-in on the most important issues in patient care and management. "...This new International Perspectives section provides a mix of personal and regional experiences from surgeons whose partnership in the management of vascular trauma was and will continue to be highly valued..." Foreword by: Norman M. Rich, June 2015 Emphasizes the current management of civilian vascular injuries with an historical reflection of pioneering contributions from the battlefield. Combines the largest existing database of military vascular trauma with the experience of one of the nation's premier civilian trauma centers. Examines operative techniques and "damage control" for vascular traumas. For the first time, includes a novel International Perspectives section featuring fascinating accounts of vascular trauma from nine leading surgeons from five continents. This section focuses on innovative surgical treatments tailored to locally developed pathways of care, training solutions, and regional injury patterns. End-to-end coverage of all phases of acute vascular injury care, including a new assessment of the implications of vascular trauma in the pre-hospital setting (i.e. point of injury and en-route care). Covers the emerging hot topics, including endovascular procedures to manage trauma, contemporary use of vascular shunts, and a modern reappraisal of resuscitative endovascular balloon occlusion of the aorta for shock. An innovative chapter on the systems approach and quality improvement in vascular trauma, offering information and tactics for all providers wishing to understand how clinical systems underpin patient outcome and recovery from this challenging injury pattern. A combined civilian and military authorship from internationally recognized authorities draws on the best available evidence, experience, and lessons-learned from Afghanistan, Iraq, and the "urban battlefield." Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices. With 44 contributing experts
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.
This brand new guide assists students, interns and residents in developing a functional understanding of the set-up, workings and interpretation of ECGs * Step-by-step graphics and short, bite-sized explanations * Covers all major cardiac abnormalities including hypertrophy, arrhythmias, conduction blocks, and pre-excitation syndromes * Begins with a section on physiology of the heart and the basic set up of ECG recording * Features top tips on what to look for, complete with illustrated examples * Supported by a companion website featuring additional practice tracings
This book identifies the key determinants in the management of hypertensive outpatients with Cardiac Target Organ Damage. It sheds light on current international guidelines by directly applying them to six representative clinical cases that reflect situations frequently encountered during clinical routine rather than emergencies or rare occurrences. The book enables cardiologists and angiologists alike to gain an overview of the most frequent cardiac dysfunctions related to hypertension: left atrial enlargement, aortic root dilatation, diastolic dysfunction, systolic dysfunction, left and right ventricular enlargement. Each case is illustrated and analyzed in detail - from family and personal history to treatment and follow-up - providing readers with valuable guidance that will help them to select the best suited diagnostic tool and treatment for each patient.
Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: * Cardiac complications in patients receiving cancer therapy * The treatment of cancer in patients with cardiovascular disease * The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.
With a growing population of young patients with congenital heart disease reaching adulthood, this unique new book offers an in-depth guide to managing the challenges and issues related to device therapy in this patient group. * The only book resource dedicated to pacing, cardiac resynchronization therapy and ICD therapy for the pediatric and congenital heart disease patient * Contains practical advice for pacemaker and ICD implantation, programming, trouble-shooting, managing complications and follow up * Up-to-date with the latest in device technology * Contains multiple graphics, device electrogram tracings, and radiographic images for clarity * Includes video clips and over 150 multiple choice questions with extended answers on companion website, ideal for self test * An invaluable resource for both the specialist pediatric cardiologist and the general cardiologist responsible for children with heart disease and pacing devices
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