Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald's Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM's Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition). Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book sheds new light on the diagnosis and treatment of Heart Failure in adult patients with congenital heart disease. This is a rapidly growing clinical issue for this group of patients and the clinical teams caring for them. The book highlights the major clinical dilemmas in diagnosing heart failure in patients with a lifelong cardiac condition and describes in details the utility of biomarkers, complex imaging and functional tests, e.g. the cardiopulmonary exercise testing. A step-wise approach to treatment is described from drug therapy through to devices and transplantation. As such, the book offers an essential guide for cardiologists and cardiac surgeons looking to optimize the management of patients with delicate physiology and complex disease.

The first comprehensive resource on transseptal catheterization. Although the transseptal technique was described half a century ago, it has remained essentially unchanged. Recent advances in cardiac electrophysiology and left heart interventions have led to renewed interest in the technique as a means of delivering modern therapeutic interventions. Until now, the knowledge required for safely gaining access to the left atrium to perform catheter ablation for atrial fibrillation or other interventions has existed only in original publications and review articles. This textbook brings all of the relevant information about this technique under one cover, with top experts in each area addressing anatomy, indications, transseptal puncture, visualization technologies, interventional devices, challenging cases, complications, and emerging tools. Electrophysiologists and interventional cardiologists will find Transseptal Catheterization and Interventions invaluable for their work. For teachers and trainees, it will be a welcome teaching tool and resource.

This volume covers everything you need to know about atrial communications; the pathology, anatomy, physiology, and natural history of treated and untreated patients; indications for intervention; surgical techniques currently used to close such defects; and transcatheter closure of these defects using approved and investigational devices. It also presents imaging techniques for guiding such procedures--including transthoracic echo, tranesophageal echo, intracardiac echo, and 2-D and 3-D technology--and using MRI to evaluate patients. Every device currently available, both approved and nonapproved, is discussed in detail along with technical analyses of how to close defects. In addition to addressing the association between PFOs and strokes and migraines, the contributors examine the status of all trials addressing transcatheter closure of ASDs and PFOs.

Modern medicine is increasingly focused on integrating the results of basic scientific research and clinical research, "translational medicine" to provide improved patient care. This collaborative approach which is a "two way street" has proven very useful in various fields in cardiovascular medicine. Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment provides extensive information on new and exciting advances in such topics as surgery and non-pharmacological treatments for atherosclerotic disease of the aorta, pulmonary arterial hypertension, cytoprotective mechanisms in the vasculature, and the "Broken Heart Syndrome." The Editors and their expert panel of contributors have explored the bi-directional and integrated approaches of translational cardiovascular medicine, linking basic science to patient care. This book is a highly useful method to understand these complex topics and provides considerable insight into important areas of translational cardiovascular medicine and key bibliographies for the reader.

The Intelligent Heart

Access the power of your heart's intelligence to improve your focus and creativity, elevate your emotional clarity, lower your stress and anxiety levels, strengthen your immune system, promote your body's optimal performance, and slow the aging process.

This book presents a thorough review of coronary angioscopy, ranging from instructions on its use to the latest advances. Starting with the structure and fundamental principles of angioscopy, it shows readers how to apply the image to comprehensive care of coronary-artery patients. Plentiful color photos and illustrations will enable readers to investigate and classify plaques and thrombi and to evaluate coronary stent- and drug-based therapies. The authors are leading researchers on angioscopy. This book offers the perfect guide not only for new clinicians but also for cardiologists who have already adopted this technique for medical examination and treatment. Angioscopy is a unique medical technique for visualizing the interior of blood vessels and helps physicians not only to diagnose the pathology but also to measure the effectiveness of Percutaneous coronary intervention (PCI) or antiarteriosclerotic drugs. Furthermore, the recently developed molecular angioscopy approach allows us to observe Low-density lipoprotein (LDL) oxide, collagen, and macrophages, and is rapidly growing in importance.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. MAXIMIZE YOUR ACLS SCORE! A Doody's Core Title! 3 STAR DOODY'S REVIEW "This book's most impressive aspect is that it presents the core topics in a direct and concise manner, that makes it a quick read and easy to understand."--Doody's Review Service Pearls of Wisdom ACLS Review, 3e is your most effective weapon in preparing for the American Heart Association's Advanced Cardiac Life Support exam. This rapid, effective review ensures your best possible performance on the exam in the shortest possible study time. There is no easier or faster way to ensure that you perform your best! FEATURES 1200+ rapid-fire questions cover all topics on the ACLS exam Powered with performance-improving pearls and other potent learning aids Updated to reflect the 2005 AMA guidelines NEW chapter on child and infant CPR and ventilation

Improve your understanding of the cardiopulmonary system with Essentials of Cardiopulmonary Physical Therapy, 4th Edition. Based on best practices prescribed in The Guide to Physical Therapist Practice, this new edition provides comprehensive coverage of anatomy, physiology, and cardiopulmonary assessment, along with expanded chapters on the growing topics of early mobilization of the ICU patient and acute care management. Using a practical approach, expert author Ellen Hillegass also discusses pathophysiology, pharmacology, and interventions in the outpatient setting. Evidence-based content reflects the latest research in the field and incorporates the use of ICF. Material uses best practices defined by the American Physical Therapy Association. Clinical tips give you real-world hints and suggestions from practicing clinicians. NEW! Expanded chapters cover early mobilization of the ICU patient and acute care management. NEW! Updated references emphasize evidence-based information from the text. NEW! Full-color printing enhances text.

Cardiac Problems in Pregnancy offers clinicians the most detailed and comprehensive guide to diagnosing and managing pregnancy-associated cardiovascular diseases currently available. Covering a wide spectrum of congenital and acquired cardiovascular conditions, its extensive contents examine diseases of the heart with an expert awareness of the implications of pregnancy and the attendant physiological changes it brings. Such guidance is vitally required in an age in which congenital and acquired heart diseases are the leading causes of non-obstetrical maternal morbidity and mortality. Featuring 36 new or extensively revised chapters, this fourth edition of the book complements coverage of the latest research and clinical advances with a complete and up-to-date bibliography of literature on pregnancy in women with cardiovascular conditions. It also serves as a practical, step-by-step companion for those caring for heart disease patients during pregnancy, labor, and the post-partum period. Contents include: Coverage of all elements of maternal cardiology Newly written chapters featuring fresh research and data Guidance on performing risk assessments and interventions both prior to and during gestation Explanations of a range of diagnostic and therapeutic approaches to cardiovascular disease in pregnant patients Drawing on expertise from across the fields of cardiovascular medicine, obstetrics, anesthesiology, cardiac surgery, pharmacology, and clinical science, Cardiac Problems in Pregnancy is designed to give invaluable support to all medical professionals involved in maximizing the safety and success of cardiologically complex pregnancies.

The book is a useful guide to the management of the most-debated hot topics of practical interest in anesthesia and intensive care. It reviews the state of the art of issues related to both intensive care medicine and anesthesia, such as assisted ventilation, ultrasound assessment of renal function, sedation during non-invasive ventilation, subarachnoid hemorrhage, coagulation disorders in septic shock, difficult airways management and hemodynamic monitoring during anesthesia. Written by leading experts and including updated references, it provides a comprehensive, easy-to-understand update on anesthesia and intensive care. The book clearly explains complex topics offering practicing clinicians insights into the latest recommendations and evidence in the field while, at the same time, making it a valuable resource for students new to the study of anesthesia and intensive care.

This book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critical elements of atherosclerosis, including foam cell formation, vascular smooth muscle cell proliferation and extracellular matrix synthesis, which over time forms bone in the heart. Osteocardiology: Cardiac Bone Formation is a practical overview of bone formation in the heart and is destined to become the cornerstone for education of medical students, residents, fellows, graduate students, physician scientists and scientists, for future research and ongoing development in medical therapies to slow or halt the progression of bone formation in the heart.

A significantly expanded third edition, this book provides a comprehensive and concise overview of cardiac arrhythmias and their ECG/telemetry manifestations, including the principles of cardiac electrophysiology, current concepts of pharmacology, clinical features, diagnoses, and state-of-the-art treatments. Additionally, the book emphasizes decision-making strategies in approaching each individual patient and the application of technical innovations in specific clinical situations. Organized into eight parts, beginning chapters introduce the concepts and principles of cardiac electrophysiology, unique rhythms, and ECG waves/signs. These chapters are designed to integrate emerging knowledge in basic science and clinical medicine. Subsequent chapters focus on the diagnosis of a variety of cardiac arrhythmias using non-invasive methodology. Throughout the book, chapters continue to analyze pharmacological and other approaches to therapy of specific arrhythmias, including supraventricular tachycardias, atrial fibrillation and flutter, ventricular arrhythmias, and bradyarrhythmias. Finally, the book closes with coverage on inherited cardiac arrhythmia syndromes including the long, short QT, and J-wave syndromes, catecholaminergic polymorphic ventricular tachycardia, and arrhythmogenic right ventricular cardiomyopathy. The third edition of Management of Cardiac Arrhythmias, is an essential resource for physicians, residents, fellows, and medical students in cardiology, cardiac surgery, vascular surgery, cardiac electrophysiology, and cardiac radiology.

A brand new series from Oxford University Press, the Oxford Clinical Imaging Guides are specifically designed to help doctors master imaging techniques. Each guide explains the principles and practice of using imaging in an easy-to-read, highly-illustrated, and authoritative manner. Acute and Critical Care Echocardiography is the first practical guide dedicated to helping doctors use transthoracic echocardiography to manage acutely and critically ill patients. The book provides readers with a grounding in theoretical evidence-based aspects of critical care echocardiography. Expert authors help the reader apply this knowledge on a daily basis via clear step-by-step techniques and a focus on problem-solving and safe practice. The book is mapped to the new accreditation syllabus in Advanced Critical Care Echocardiography set by the British Society of Echocardiography, ensuring that it is relevant to professional standards and teaches doctors exactly what they need to know. Self-assessment questions help readers retain what they have learned and revise for exams. An essential day-to-day reference and interactive guide, this unique book should never be far from the critical care medic's side.

In this compilation, the authors discuss peripartum cardiomyopathy (PPCM), a rare but serious form of heart failure affecting women in the last month of pregnancy or early postpartum. It is diagnosed by documented left ventricular systolic dysfunction in the absence of another demonstrable cause in a previously healthy woman. Prognosis is variable and appears to be positively related to reversal of ventricular dysfunction. Prompt diagnosis with institution of intense therapy by a multidisciplinary team is a prerequisite for improved outcome. Pharmacotherapy remains the mainstay of treatment for PPCM, and the management strategy is broadly aligned with established guidelines for cardiac failure. Nevertheless, individually tailored therapy is often required for treatment of clinical sequelae, as well as for the management of delivery. At present, we lack the understanding to be able to effectively risk stratify patients and identify those susceptible to disease progression. As such, further research into this area is crucial in order to develop an understanding of which women are at greatest long-term risk, as well as to more effectively manage the condition. The authors also discuss idiopathic dilated cardiomyopathy (DCM), the second most frequent cause of heart failure and is associated with a survival rate of less than 50% at 10 years. The diagnosis is clinical and established by the presence of both left ventricle enlargement and systolic dysfunction. MRI has been increasingly applied to the evaluation of cardiovascular disease and has become the first-line imaging modality in the assessment of many types of congenital and acquired cardiovascular disorders; it could be used for global analysis of ventricular structure and function, myocardial mass and viability. It is nowadays the gold standard for assessing RV systolic function and is being increasingly used in this regard. Additionally, more than 40 genes have been identified as causative gene associated with hereditary DCM. A genetic diagnosis can confirm a hereditary DCM clinical diagnosis and it can help predict disease risks for family members before the onset of symptoms. Thus, finding predictors of DCM is of great significance as this may help doctors take precautions as soon as possible and is beneficial for long-term outcomes.

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Workshop on Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges, STACOM 2014, held in conjunction with MICCAI 2014, in Boston, MA, USA, in September 2014. The 30 revised full papers were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics such as sections on cardiac image processing; atlas construction; statistical modelling of cardiac function across different patient populations; cardiac mapping; cardiac computational physiology; model customization; atlas based functional analysis; ontological schemata for data and results; integrated functional and structural analyses; as well as the pre-clinical and clinical applicability of these methods.

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

Atrial Fibrillation is becoming a twenty-first century epidemic. It remains the most common form of sustained arrhythmia with significant mortality, morbidity and cost to the health care system. It is the most common cause of hospital admissions among all arrhythmias. Its prevalence increases with the aging population and is often associated with many other cardiac and noncardiac conditions, most notably congestive heart failure, hypertension, diabetes, and coronary artery disease. Although significant progress in understanding the epidemiology, natural history and mechanism has been made, the antiarrhythmic therapy in patients with Atrial Fibrillation is less satisfactory. Management of Atrial Fibrillation: A Practical Approach is the perfect pocket guide for those who care for patients afflicted by Atrial Fibrillation. From the history of the condition and the subsets of patients, to therapeutic and preventive procedures, Management of Atrial Fibrillation comprehensively covers all aspects in managing this increasingly prevalent disorder. Written by leading authorities in the field with vast experience in practical medicine, the book creates a clinically orientated, evidence based "fast fact" type resource for cardiologists, trainees and related healthcare professionals.

Coronary Atherosclerosis: Current Management and Treatment addresses the leading cause of death worldwide - coronary artery disease. Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis, and the functional status of the coronary plaque and is a disease cardiologists manage every day. Prevalence of coronary artery disease is increasing as a greater number of people live longer and rising rates of obesity contribute to poor health.

This brand new title, written by a leading international team of Editors, addresses the pathophysiology of disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment including future therapies and long term outcomes. It includes every aspect of coronary artery disease and highlights the optimal treatment for different clinical scenarios. The inclusion of personal perspectives from key opinion leaders, full color images and ancillary video files make this a key resource.

Key topics include:

• Pharmacology of coronary artery disease (CAD)
• Up-to-date evidence on pathophysiology
• Non-invasive imaging
• Current evidence for risk stratification
• Invasive imaging/cutting edge technology
• Clinical decision making from masters in the field

Coronary Atherosclerosis: Current Management and Treatment provides a state of the art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.

Cardiopulmonary resuscitation (CPR) is an emergency procedure which is performed in an effort to manually preserve intact brain function until further measures are taken to restore spontaneous blood circulation and breathing in a person in cardiac arrest. Sudden cardiac arrest is the leading cause of death in the industrialized world. Early bystander's CPR has been recognized as one of the most effective interventions in improving outcome and as an essential link of the survival's chain. In this book the authors present current research in the study of CPR, including predictors of survival from out- of-hospital cardiac arrest; aspirin resistance in cardiovascular disease; out-of-hospital cardiac arrest in children and results of experience from a cardiopulmonary resuscitation program in Spain.

Mitral regurgitation (MR) affects millions of patients worldwide. It is a progressive condition that can worsen when left untreated, possibly leading to compensatory remodeling of the left ventricle. This can result in reduced functional capacity, poor quality of life, repeat hospitalizations, and even death from heart failure. Open, arrested heart surgery has until now been the therapeutic treatment of choice. However, many high-risk patients cannot tolerate traditional heart surgery and continue to suffer from severe MR. In Percutaneous Mitral Leaflet Repair: MitraClip Therapy for Mitral Regurgitation, international experts discuss the clinical application of percutaneous mitral valve therapies for this subsect of patients, focusing on the MitraClip device. These new therapeutic developments will form an essential component of the interventional cardiologists' armamentarium in treating MR patients and will be of interest to every practicing cardiologist. Key topics include: An overview of the anatomy and pathophysiology of the mitral valvular complex and MR EVEREST trial outcomes, and the development of percutaneous edge-to-edge repair Updates on the global experience with this new therapy Patient selection and the role of percutaneous therapies for high-risk patients Echocardiographic guidance, including practical tips for the use of transesophageal echocardiography during a procedure Step-by-step techniques, plus tips and tricks for getting the best results for your patients Special considerations for treating the returning MR repair patient Discussion of the European experience since CE approval Future directions in percutaneous mitral valve therapies

This new, expanded edition of the Dictionary of Cardiac Pacing, Electrophysiology, and Arrhythmias addresses the growing need for education about implantable cardiac devices and arrhythmia management. Perfect for the medical device industry and allied professionals, this illustrated reference updates the language of cardiac pacing, electrophysiology, arrhythmias, and resynchronization therapy. Features include: 3,386 terms, including more than 1,500 new entries and revised definitions; 136 figures and tables, illustrating terms concretely and lending depth to definitions and concepts; extensive cross-references to enable users to find terms with one or more synonyms or related concepts; selected clinical trial descriptions and references; appendices that list accepted and commonly used acronyms, abbreviations, and their meanings.

This text, published in the profession's centenary year, traces the history of cardiac surgery from ancient times to the present, detailing clinical developments with facsimilies of the original articles, consent forms from the first heart transplant, newspaper articles, and correspondence. The text follows a set pattern, describing the historical background to each new procedure, facsimilies of the original articles, bibliography of the main clinicians, and a commentary putting each development into its historical context.