Following the tradition of its predecessor, the fifth edition of Nutrition: Maintaining and Improving Health continues to offer a wide-ranging coverage of all aspects of nutrition while providing new information to this edition including: Increased coverage of experimental and observational methods used in nutrition In-depth focus on the nutritional implications of the increased adoption of vegetarian and vegan lifestyles Streamlined referencing - a short selected list of key references at the end of each chapter with URL links to free additional resources where possible Discussion of nutrition debates Critical coverage of "medicinal uses of food" including superfoods, functional foods and dietary supplements Updated bullet point summaries of key points after each major topic within each chapter The author provides an evidence-based evaluation of many key nutrition beliefs and philosophies. The book contains in-depth and critical reviews of the methods used to evaluate nutritional intakes/status and the observational and experimental used to investigate putative links between dietary factors and health outcome. It covers the role of food as a source of energy and nutrients while discussing the non-nutritional roles of food and the social and psychological factors that influence food choice. Presenting a critical discussion on the value of nutrition research linking specific foods or nutrients to specific diseases which encourages students to question the value of some current nutrition research. This is essential reading for all nutrition and dietetics students with different backgrounds who are studying nutrition as a specific discipline for the first time.

The establishment of precise and reliable biomarker tests for the early stages of cardiovascular disease is of great importance and can be the cornerstone in the prevention of future cardiovascular disease (CVD). Furthermore, some biomarkers may provide important information concerning the pathogenesis of CVD or appear to be useful in risk stratification, in CVD diagnosis, or in monitoring therapy; many others may be risk factors themselves, representing therefore potential targets of therapy. The ideal biomarker should have the following characteristics: highly sensitive, specific, reliable, accessible, standardized, dependable, cost effective, and easily interpretable by clinicians. The present book focuses on the presentation and evaluation of the most promising classical and novel biochemical markers used in CVD (coronary artery disease, hypertension, heart failure, hyperlipidemia, peripheral arterial disease). The underlying pathophysiological characteristics of each biomarker, as well as potential clinical implications in daily practice are reviewed in this book.

Acute Coronary Syndrome (ACS) is a growing global menace with patients increasing in developing countries where tobacco and food play a major role. Its treatment guidelines and research results have proliferated in academia, but practical applications lag behind that research. This book addresses this void. Guidelines for treatment of ACS present in-depth reading for practicing cardiologists, thus preventing clinical application. The book aims to appraise readers of real-world situations and suggestions to help them acquire up-to-date knowledge on ACS and its effective diagnosis, prognosis and management. Key Features Covers recent advances in ACS management and pharmacotherapy Discusses the guidelines for treatment of ACS for the professional cardiologist to apply to clinical practice Explores the topics with the help of case scenarios Follows a concise, yet comprehensive approach Features a chapter on 'When to Transfer,' which discusses how to spot unstable patients or those heading towards shock

Acute Coronary Syndrome (ACS) is a growing global menace with patients increasing in developing countries where tobacco and food play a major role. Its treatment guidelines and research results have proliferated in academia, but practical applications lag behind that research. This book addresses this void. Guidelines for treatment of ACS present in-depth reading for practicing cardiologists, thus preventing clinical application. The book aims to appraise readers of real-world situations and suggestions to help them acquire up-to-date knowledge on ACS and its effective diagnosis, prognosis and management. Key Features Covers recent advances in ACS management and pharmacotherapy Discusses the guidelines for treatment of ACS for the professional cardiologist to apply to clinical practice Explores the topics with the help of case scenarios Follows a concise, yet comprehensive approach Features a chapter on 'When to Transfer,' which discusses how to spot unstable patients or those heading towards shock

Fascia, Function, and Medical Applications is essential reading for medical and allied health practitioners who want to bring scientific insights of the importance of fascia to human health into their clinical practices. Fascia - the biodynamic tissue that connects every muscle, bone, organ, and nerve in the body - is fast becoming the latest trend in healthcare and allied health modalities. This book is edited by David Lesondak, University of Pittsburgh Medical Center, author of the international bestseller Fascia: What it is and why it matters, and Angeli Maun Akey, MD, international physician educator and board certified in both internal and integrative medicine. It contains contributions from a team of top researchers and expert practitioners including physicians, clinicians, therapists, dissectors, and surgeons. Fully illustrated in color, this book presents the latest scientific knowledge of fascia and explains insights into problems like chronic pain and myriad musculoskeletal symptoms that may not respond to conventional treatments. It gives practitioners the information they need to make better decisions to improve the health of patients often without pharmaceuticals or surgeries. FEATURES * Provides comprehensive overview of how fascia, as a tissue and a system, affects various body functions and systems, from musculoskeletal disorders to nervous system, circulatory, and auto-immune function. * A section devoted to medical applications highlights a comprehensive and critical overview of various fascial therapies. * Gives practitioners the knowledge they need to refer or add as an adjunct therapy to their department or rehabilitation team. This is a cutting-edge, practical guide that will appeal to researchers, physicians, and clinicians alike.

Selected as a Doody's Core Title for 2022! Written and edited by Dr. Marc S. Sabatine and a team of cardiologists from Brigham and Women's Hospital and Harvard Medical School, the new second edition of Pocket Cardiology has been greatly expanded to be made even more indispensable for everyday use. Part of the highly popular and respected Pocket Notebook series, this essential guide puts vital clinical information about a broad range of issues in cardiovascular medicine at your fingertips in seconds. Contains expanded and fully updated core clinical topics on cardiovascular evaluation tools, preventative cardiology, coronary disease, heart failure, critical care, valvular heard disease, pericardial heart disease, vascular disease, arrhythmias, and adult congenital heart disease in the familiar concise format, with bulleted lists, tables, and algorithms for quick reference. Features a new, more durable binding in the classic Pocket Notebook style. Includes new contributions from the fields of cardiovascular critical care, interventional cardiology, cardiac imaging, and adult congenital heart disease. Includes useful illustrations of echocardiography, cardiac nuclear imaging, and coronary angiography, as well as EKG tracings. Contains current, evidence-based clinical recommendations, supported by key references to the most recent practice guidelines, high-tier reviews, and important clinical trials. An invaluable tool for cardiovascular physicians and fellows, medical residents, and others who are interested in cardiology.

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

The landmark text that belongs in the hands of every cardiologist fully updated and reorganized to make it more patient-centric than ever World-famous for its authority and clinical relevance, Fuster and Hurst's The Heart is cardiology's longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classic offers a solid foundation in cardiovascular medicine and complete coverage of all major cardiovascular topics. This fifteenth edition presents a greater focus on the practicalities of patient care. Additionally, the content is ordered in a more methodical pattern, from mechanism to management. Reflecting the latest technical, therapeutic, and clinical advances, Fuster and Hurst's The Heart provides invaluable concise summaries of major new trials and guidelines. Authoritative Coverage and Unmatched Utility: Central Illustrations New section on cardiovascular critical care New chapter "Cardiovascular Disease and COVID-19" Chapter summaries ACC/AHA/ESC guidelines in all chapters 1,200+ photos and illustrations Sections Include: Risk Factors for Cardiovascular Disease Atherosclerosis and Coronary Heart Disease Diseases of the Great Vessels and Peripheral Vessels Valvular Heart Disease Rhythm and Conduction Abnormalities Heart Failure Diseases of the Pericardium Cardiopulmonary Disease Critical Cardiovascular Care Adult Congenital Heart Disease Special Populations and Topics in Cardiovascular Disease

Mitral regurgitation (MR) affects millions of patients worldwide. It is a progressive condition that can worsen when left untreated, possibly leading to compensatory remodeling of the left ventricle. This can result in reduced functional capacity, poor quality of life, repeat hospitalizations, and even death from heart failure. Open, arrested heart surgery has until now been the therapeutic treatment of choice. However, many high-risk patients cannot tolerate traditional heart surgery and continue to suffer from severe MR. In Percutaneous Mitral Leaflet Repair: MitraClip Therapy for Mitral Regurgitation, international experts discuss the clinical application of percutaneous mitral valve therapies for this subsect of patients, focusing on the MitraClip device. These new therapeutic developments will form an essential component of the interventional cardiologists' armamentarium in treating MR patients and will be of interest to every practicing cardiologist. Key topics include: An overview of the anatomy and pathophysiology of the mitral valvular complex and MR EVEREST trial outcomes, and the development of percutaneous edge-to-edge repair Updates on the global experience with this new therapy Patient selection and the role of percutaneous therapies for high-risk patients Echocardiographic guidance, including practical tips for the use of transesophageal echocardiography during a procedure Step-by-step techniques, plus tips and tricks for getting the best results for your patients Special considerations for treating the returning MR repair patient Discussion of the European experience since CE approval Future directions in percutaneous mitral valve therapies

Heart Failure, Second Edition has been updated to provide the latest advancements in heart failure research. Supplemented by more than 200 high-quality figures and illustrations, the book helps cardiologists and emergency care physicians quickly and accurately identify the cause and severity of a patient's cardiac impairment.

New topics in this edition include:

• Developments in mechanical and pharmacologic treatments
• Discoveries in developmental biology
• Up-and-coming imaging modalities
• Surgical options for mechanical circulatory support and cardiac transplantation
• Pharmacogenomics and gene-based and cell-based therapies
• Gene expression/recurrence in heart failure
• Changes in metabolic substrate utilization and pathways

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

The prevalence of coronary artery disease is increasing due to rising rates of obesity and the fact that a greater number of people are living longer. Coronary Atherosclerosis: Current Management and Treatment addresses this leading cause of death worldwide. Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis and the functional status of the coronary plaque. This volume, written by a leading international team of editors, addresses the pathophysiology of the disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment, including future therapies and long-term outcomes. The inclusion of personal perspectives from experts, full-color images and ancillary video files make this a key resource. Key topics include: Pharmacology of coronary artery disease (CAD) Up-to-date evidence on pathophysiology Invasive and non-invasive imaging Current evidence for risk stratification Clinical decisionmaking Coronary Atherosclerosis: Current Management and Treatment provides a state-of-the-art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.

Chronic pain places a tremendous burden on both the patient and the healthcare system. The use of opioids to address pain has resulted in negative impacts. As practitioners work to undo the current opioid crisis, options to manage pain need a new approach. Advanced Therapeutics in Pain Medicine offers pioneering approaches to this intransigent problem providing a functional medicine approach toward treating pain. This book is dedicated to the advancement of non-opioid therapeutic options that offer real progress in reaching a future of better pain management. With an emphasis on pathophysiology, chapters review various types of pain and propose comprehensive treatment plans. These include manual therapies, novel pharmacologic and plant-based approaches, hormonal effects on pain pathways, as well as psychological and lifestyle interventions. Features * Written by a multi-discplinary team, the book provides clinicians with multiple non-opioid treatment considerations. * Enables practitioners to shift from a "one size fits all' treatment approach toward individualized patient care. * Includes case studies to help educate the provider on how to implement treatment plans in practice. Written by a team of physicians, pharmacists, psychologists and researchers, this important book offers a much needed step forward in optimizing pain care and benefits practitioners who care for patients experiencing chronic pain.

Chronic pain places a tremendous burden on both the patient and the healthcare system. The use of opioids to address pain has resulted in negative impacts. As practitioners work to undo the current opioid crisis, options to manage pain need a new approach. Advanced Therapeutics in Pain Medicine offers pioneering approaches to this intransigent problem providing a functional medicine approach toward treating pain. This book is dedicated to the advancement of non-opioid therapeutic options that offer real progress in reaching a future of better pain management. With an emphasis on pathophysiology, chapters review various types of pain and propose comprehensive treatment plans. These include manual therapies, novel pharmacologic and plant-based approaches, hormonal effects on pain pathways, as well as psychological and lifestyle interventions. Features * Written by a multi-discplinary team, the book provides clinicians with multiple non-opioid treatment considerations. * Enables practitioners to shift from a "one size fits all' treatment approach toward individualized patient care. * Includes case studies to help educate the provider on how to implement treatment plans in practice. Written by a team of physicians, pharmacists, psychologists and researchers, this important book offers a much needed step forward in optimizing pain care and benefits practitioners who care for patients experiencing chronic pain.

Lactic acid bacteria (LAB) are a diverse group of bacteria that comprise low GC content Gram-positive cocci or rods that produces lactic acid as the major end product of the fermentation process. Bifidobacterium genera may also be considered as a part of the LAB group for possessing some similar phenotypical characteristics despite the higher GC content. The key feature of LAB metabolism is efficient carbohydrate fermentation. This contributes to the production of several microbial metabolites that result in the improvement of flavor and texture of fermented foods, in addition to its positive impact on the human health when LAB is administered as a probiotic. The book deals with advances made in the functionalities of LAB, such as their effect on vitamin D receptor expression, impact on neurodegenerative pathologies, production of B-vitamins for food bio-enrichment, production of bacteriocins to improve gut microbiota dysbiosis, production of metabolites from polyphenols and their effects on human health, effect on reducing the immunoreaction of food allergens, as biological system using time-temperature to improve food safety, and the use of probiotics in animal feed. The book also reviews the use of LAB and probiotic technologies to develop new functional foods and functional pharmaceuticals.

Ancestral Diets and Nutrition supplies dietary advice based on the study of prehuman and human populations worldwide over the last two million years. This thorough, accessible book uses prehistory and history as a laboratory for testing the health effects of various foods. It examines all food groups by drawing evidence from skeletons and their teeth, middens, and coprolites along with written records where they exist to determine peoples' health and diet. Fully illustrated and grounded in extensive research, this book enhances knowledge about diet, nutrition, and health. It appeals to practitioners in medicine, nutrition, anthropology, biology, chemistry, economics, and history, and those seeking a clear explanation of what humans have eaten across the ages and what we should eat now. Features: Sixteen chapters examine fat, sweeteners, grains, roots and tubers, fruits, vegetables, and animal and plant sources of protein. Integrates information about diet, nutrition, and health from ancient, medieval, modern and current sources, drawing from the natural sciences, social sciences, and humanities. Provides comprehensive coverage based on the study of several hundred sources and the provision of over 2,000 footnotes. Presents practical information to help shape readers' next meal through recommendations of what to eat and what to avoid.

Ancestral Diets and Nutrition supplies dietary advice based on the study of prehuman and human populations worldwide over the last two million years. This thorough, accessible book uses prehistory and history as a laboratory for testing the health effects of various foods. It examines all food groups by drawing evidence from skeletons and their teeth, middens, and coprolites along with written records where they exist to determine peoples' health and diet. Fully illustrated and grounded in extensive research, this book enhances knowledge about diet, nutrition, and health. It appeals to practitioners in medicine, nutrition, anthropology, biology, chemistry, economics, and history, and those seeking a clear explanation of what humans have eaten across the ages and what we should eat now. Features: Sixteen chapters examine fat, sweeteners, grains, roots and tubers, fruits, vegetables, and animal and plant sources of protein. Integrates information about diet, nutrition, and health from ancient, medieval, modern and current sources, drawing from the natural sciences, social sciences, and humanities. Provides comprehensive coverage based on the study of several hundred sources and the provision of over 2,000 footnotes. Presents practical information to help shape readers' next meal through recommendations of what to eat and what to avoid.

This comprehensively revised new edition prepares the reader for the cardiology board examination, as well as provide a concise review of the essentials of general cardiology and the less common but clinically relevant topics in a dynamic and time-efficient manner, augmenting existing learning. It uses board-style questions and answers at the end of each topic, enabling readers to test their learning and commit key concepts to long-term memory. Instructive figures and tables are used to consolidate teaching points. This book also contains practical tips from recent board exam takers and other resources in order to make best use of the reader's limited time. In the MGH Cardiology Board Review, the Editors have compiled the expertise of over 60 experienced authors in a succinct volume, applying methods thoroughly tested in Board Review. In addition, two very important sections on ECGs and images are included, contents of which are derived from the board examination answer keys, the very ones that readers are expected to know. Plans on how to best approach board examination preparation and what additional resources to go to are provided. In short, this book has all the strengths to ensure your success on the boards exam.

Cardiac disease is one of the leading causes of maternal morbidity and mortality. Catastrophic outcomes typically encountered are due to gaps in knowledge and communication between health care providers. There is a great need for a standardized approach for care of this very high-risk group of pregnant women. The book encompasses detailed obstetrics and cardiology perspectives that are crucial in the management of the commonly encountered cardiac conditions in pregnancy. This text aims to provide guidance to the whole team caring for a pregnant cardiac patient consisting of obstetricians, maternal-fetal medicine, hospitalists, cardiologists, obstetric anaesthesiologists, emergency physicians, primary care providers and nurses. Features: Cardio-Obstetric team organization Preconception counselling and family planning considerations Cardiovascular disease screening and risk stratification of a pregnant cardiac patient Management of a wide spectrum of cardiovascular diagnoses through use of checklists and algorithms in a simple format Essential key points for each cardiac diagnosis

Cardiac disease is one of the leading causes of maternal morbidity and mortality. Catastrophic outcomes typically encountered are due to gaps in knowledge and communication between health care providers. There is a great need for a standardized approach for care of this very high-risk group of pregnant women. The book encompasses detailed obstetrics and cardiology perspectives that are crucial in the management of the commonly encountered cardiac conditions in pregnancy. This text aims to provide guidance to the whole team caring for a pregnant cardiac patient consisting of obstetricians, maternal-fetal medicine, hospitalists, cardiologists, obstetric anaesthesiologists, emergency physicians, primary care providers and nurses. Features: Cardio-Obstetric team organization Preconception counselling and family planning considerations Cardiovascular disease screening and risk stratification of a pregnant cardiac patient Management of a wide spectrum of cardiovascular diagnoses through use of checklists and algorithms in a simple format Essential key points for each cardiac diagnosis

Bamboo is an ordinary plant with extraordinary properties. With its high growth rate and self-renewing ability, bamboo's sustainability is unparalleled. Bamboo is an important resource for a healthy planet, and its shoots hold manifold nutritional benefits. Based on 18 years of research, Bamboo Shoot: Superfood for Nutrition, Health and Medicine details health-promoting bioactive compounds found in bamboo and offers practical guidance on how this vegetable, bamboo shoot, is used for food fortification. Already a delicacy in many Asian countries, bamboo shoots aid in the prevention of cardiovascular disease, cancer, diabetes, hypertension and obesity. Exploring the tradition and culture of bamboo in Asian countries, this book also provides information on the science behind the nutritional value of bamboo shoots. Written by individuals with expertise in bamboo shoot nutrition and fully illustrated in colour, this book reveals the antioxidant activity of bamboo shoots and discusses the potential for bamboo to be used as an ingredient in functional foods and nutraceuticals. This highly practical book discusses processing and packaging of shoots for long term storage and using bamboo in the development of novel food products. Features: Elucidates the nutrients and phytochemicals in over 30 bamboo species and includes a glossary of scientific names Highlights the nutraceutical and antioxidant properties of bamboo Describes novel healthy food products fortified with bamboo shoots and provides food recipes using bamboo Explains how bamboo can help countries achieve their sustainable development goals, from poverty reduction, food security, improved nutrition and prevention of diseases to climate change mitigation and inclusive green economic development Aimed at professionals in the nutrition and food processing industry, this book appeals to those with an interest in incorporating bamboo into a healthier lifestyle. Endorsements This is a unique book interestingly crafted to highlight the important nutritional, health and medicinal aspects of Bamboo, an area that is greatly underexplored. It will bring awareness that bamboo shoots are a low calorie, high fibre nutritious vegetable packed with vitamins and minerals. - Prof. Cherla Sastry, Founding Director General INBAR and Adjunct Professor, University of Toronto, Canada This book brings a series of answers to all questions related to bamboo as a superfood [and will] enlighten readers how to transform bamboo shoots using either traditional or modern techniques, how to package them and how to use them as a functional and nutraceutical food. It also provides a series of cooking recipes for healthy eating while we enjoy our food. - Ximena Londono, Founder, A Bamboo and Guadua Paradise, Colombia

MRI techniques have been recently introduced for non-invasive qualification of regional myocardial mechanics, which is not achievable with other imaging modalities. Covering more than twenty-three years of developments in MRI techniques for accessing heart mechanics, this book provides a plethora of techniques and concepts that assist readers choose the best technique for their purpose. It reviews research studies and clinical trials that implemented MRI techniques for studying heart mechanics.

Based on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.

In this issue of Cardiology Clinics, guest editors Drs. Sharmila Dorbala and Piotr Slomka bring their considerable expertise to the topic of Nuclear Cardiology. Top experts in the field cover key topics such as advances in single-photon emission computed tomography hardware and software; technical aspects of cardiac PET; novel PET applications and radiotracers of imaging cardiovascular pathophysiology; radionuclide tracers for myocardial perfusion imaging and blood flow quantification; and more. Contains 16 relevant, practice-oriented topics including artificial intelligence in nuclear cardiology; what is new in risk assessment in nuclear cardiology; radionuclide assessments and imaging for various conditions; low radiation dose myocardial perfusion imaging; myocardial perfusion imaging with calcium score; and more. Provides in-depth clinical reviews on nuclear cardiology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This timely Second Edition of a landmark reference furnishes in-depth examinations of the latest developments in the physiology, pathophysiology, and clinical relevance of the respiratory muscles and chest wall-reflecting the explosion of information that has occurred since the publication of the previous edition.