This issue of Cardiac Electrophysiology Clinics--edited by Drs. Amin Al-Ahmad, Raymond Yee, and Mark Link--will focus on Contemporary Issues in Patients with Implantable Devices. Topics include, but are not limited to: Management of Device infections; Device longevity; Inappropriate ICD therapies; ILR for cryptogenic stroke; ICD implantation without DFT testing; S-ICD; Lead extraction; Use of the WCD as a bridge to ICD; Important parameters for ICD selection; Leadless pacemakers; Management of perioperative anticoagulation for device implantation; HIS bundle pacing; Single coil ICD leads; Venous system interventions for device implantation; and Remote monitoring.

Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine.

This issue of Cardiology Clinics, edited by Dr. Amal Mattu and Dr. John Field, focuses Emergency Cardiology. Topics include, but are not limited to: Evaluation of Chest Pain and Acute Coronary Syndromes; Evolving Electrocardiographic Indications for Emergent Reperfusion; Cardiac biomarkers in emergency care; Non-ST-Segment Elevation Myocardial Infarction; Cardiogenic Shock, Acute Dyspnea and Decompensated Heart Failure; Evolving Strategies for Management of Cardiac Arrest; Multidisciplinary management post-cardiac arrest; Acute Myopericardial Syndromes; Acute Valvular Heart Disease; Ventricular Arrhythmias; Atrial Fibrillation, A New Face of Cardiac Emergencies: HIV-Related Cardiac Disease; Cardiovascular Emergencies in Pregnancy, and Blunt Cardiac Trauma.

Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle acts as a bridge between physiology and physics by discussing the physiology and calcium signaling mechanism in cardiac and smooth muscle. By exploring the mechanism of the cyclic release of stored Ca^(2+) in the SR or ER, this book covers the cell communication system, including excitable cells, recognizing the most relevant mechanisms of cell communication. Serving as a bridge between physiology and physics, coverage spans the physiology and calcium signaling mechanism in cardiac and smooth muscle, offering insight to physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists.

This issue of Cardiology Clinics, edited by Dr. Stephen Nicholls, focuses on Lipidology. Topics include, but are not limited to: Impact of lipoproteins on atherobiology; Lessons from genomic studies; Lipids and lipoproteins in risk prediction; Optimizing statins and ezetimibe in guideline focused management; Statin intolerance; Lipid lowering agents and diabetes risk; PCSK9 inhibitors; Bempedoic Acid; Triglyceride rich lipoproteins; Omega 3 Fatty Acids; Lipoprotein; CETP inhibitors; HDL infusions; and Targeting HDL functionality.

This unique book shows ECGs as they really appear in everyday practice and not in the usual format as presented in textbooks. Each of the 100 traces is accompanied by a list of the main diagnostic features along with a full report of the ECG, noting any other clinical details that may be important. Boxes list the common causes of the abnormalities shown. Key features of the ECG are reproduced again using annotations to guide the reader. Thus the book provides in itself a collection of full 12-lead ECGs of a wide range of common clinical problems encountered in casualty. This collection of traces, updated for this Third Edition with new cases, will be invaluable to all involved in the diagnosis of the most commonly encountered ECG abnormalities. Provides full size and realistic reproduction of 12-lead ECGs Includes a wide range of cardiac abnormalities Highlights the diagnostic criteria for each abnormality listed Reflects how this subject is encountered in practice Assists the reader by illustrating alongside the key features of the recording; thus these can be viewed in relation to the whole trace The Third Edition is spiral bound to make it easier for a reader to lay the ECG traces flat for study. Several new cases are included plus a new section on the approach to the ECG has been added.

This issue of Cardiology Clinics, edited by Dr. Fernando Fleischman, will cover a broad range of topics related to Aortic Diseases. Subjects discussed include, but are not limited to: Diseases of the Aortic Root; Genetic Disorders and Indications for Intervention, Type A Dissections; Endovascular Treatment Options for the Aortic Arch; Treatment of Complex Thoracoabdominal Aortic Disease; Treatment of Abdominal Aortic Pathology; and Neuroprotection Strategies in Aortic Surgery, among others.

This issue of Interventional Cardiology Clinics, edited by the series Editor-in-Chief, Dr. Matthew Price, will cover Transcatheter Closure of Patent Foramen Ovale. Some of the topics discussed in this issue include, but are not limited to, PFO and the Interatrial Septum: Clinical-Anatomic Correlations; Current Dataset for PFO Closure in Cryptogenic; Stroke: Randomized Clinical Trials and Observational Studies; PFO closure: Devices and Technique; Identification and quantification of PFO-mediated shunts: echocardiography and transcranial Doppler; PFO closure for Hypoxemia; and Imaging Assessment of the interatrial Septum for ASD and PFO closure, among others.

To say this book is just about coronary heart disease would demean its real value. The author has brought together from innumerable sources, information that places coronary artery disease in a historical, evolutionary, and scientific context. The book is eminently readable by both the lay public and members of the medical profession. Physicians and health workers often fail to appreciate the historical and scientific context of disease. That is because they are critically involved in the day-to-day management of patients. This book makes the topic exciting and provides extraordinary insight into the importance of history and how science, society and social circumstances interact. This book is less about coronary artery disease than it is about certain contexts that author believes are important for a better understanding of this disease and several others. The contexts are biological, clinical, managerial, social and historical, and each chapter is an inquiry into one or more of them. A theme common especially to the last chapters is that the balance between principle and diversity, or between Platonic idealism and Aristotelian empiricism, has been shifted too far in favour of the former, and that this imbalance is inimical to science, agriculture and clinical medicine. A major theme of this book is that we cannot rely on molecular biology and biotechnology to provide solutions to coronary artery disease. Instead, government must integrate health policy with policies for science, industry, urban planning and agriculture. The book is intended for health care professionals, including researchers and administrators, and it is intended for informed laypersons, including politicians, with a general interest in our health care systems.

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli, will cover Contemporary Challenges in Sudden Cardiac Death. Topics covered in this issue include Pathophysiology; Basic electrophysiological mechanism; Channelopathy and Myopathy as causes of sudden cardiac death; Public access to defibrillation; Sudden cardiac death in children adolescence; Sudden cardiac death in specific cardiomyopathies; Ventricular arrhythmias and sudden cardiac death; lessons learned from cardiac implantable rhythm devices; future directions, and more.

This issue of Physician Assistant Clinics, guest edited by Daniel Thibodeau MHP, PA-C, DFAAPA, is devoted to Cardiology. Articles in this issue include: Hypertension: Evaluation, Management and Keeping Patients in the Safe Zone; Cardiovascular Risk and Assessment: Impact of Comorbidities to the Cardiovascular System; Arrhythmia Detection and Management; Anticoagulation: The Successes and Pitfalls of Long-term Management; Dyslipidemia: Long-term Management and Other Uses of Statins for Cardiac Disease; Acute Coronary Syndrome: Care After a Patient Event and Strategies to Improve Adherence; Evaluation of Chest Pain in the Primary Care Setting; Ischemic Heart Disease; Heart Failure and Cardiomyopathy; Pulmonary Hypertension and Thromboembolism: Long-term Management and Chronic Oral Anticoagulation; Approaches to Valvular Disease in the Primary Care Setting; and Syncope: Initial Evaluation and Workup in the Primary Care Office.

This issue of Interventional Cardiology Clinics, guest edited by Dr. Srihari S. Naidu, will discuss Interventional techniques for Heart Failure. Subjects covered in the articles include, but are not limited to: Invasive Hemodynamics of Myocardial Disease: Systolic and Diastolic Dysfunction; Invasive Hemodynamics of Pericardial Disease: Constriction and Tamponade; Invasive Hemodynamics of Pulmonary Disease and the Right Ventricle; TAVR and MitraClip to Reverse Heart Failure; Mechanical Circulatory Support in Acute Decompensated Heart Failure and Shock; Adult Congenital Interventions in Heart Failure; Future Directions in Device Treatment of Heart Failure; and Prioritizing and Combining Interventional Therapies for Heart Failure, among others.

From basic clinical facts to new advanced guidelines, Practical Cardiology, by Drs. Majid Maleki, Azin Alizadehasl, and Majid Haghjoo, is your new go-to resource for new developments in cardiology knowledge, imaging modalities, management techniques, and more. This step-by-step, practical reference is packed with tips and guidance ideal for residents, fellows, and clinicians in cardiology, as well as internal medicine, cardiac surgery, interventional cardiology, and pediatric cardiology. Features a wealth of information online and in print, including practical points from recently published guidelines, ECGs, hemodynamic traces of advanced imaging modalities in real patients, and much more. Offers a comprehensive review of cardiovascular medicine, from basic to advanced.

Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and biochemical alteration including metabolic homeostasis and reprogramming of gene expression. Changes in metabolic pathways are generally short-lived and reversible, while the consequences of gene expression are a long-term process and may lead to permanent alternation in the pattern of adaptive responses.
The heart possesses remarkable ability to adapt itself against any stressful situation by increasing resistance to the adverse consequences. Stress composes the foundation of many degenerative heart diseases including atherosclerosis, spasm, thrombosis, cardiomyopathy, and congestive heart failure. Based on the concept that excessive stress may play a crucial role in the pathogenesis of ischemic heart disease, attempts were made to design methods for preventing of myocardial injury. Creation of stress reactions by repeated ischemia and reperfusion or subjecting the hearts to heat or oxidative stress enables them to meet the future stress challenge. Repeated stress exposures adapt the heart to withstand more severe stress reactions probably by upregulating the cellular defense and direct accumulation of intracellular mediators, which presumably constitute the material basis of increased adaptation to stress. Thus, the powerful cardioprotective effect of adaptation is likely to originate at the cellular and molecular levels that compose fundamental processes in the prophylaxis of such diseases.
Volume six of the Advances in Organ Biology series contains state-of-the-art reviews on myocardial preservation and cellular adaptation from the leading authorities in this subject.

This issue of Cardiology Clinics, edited by Drs. Gerald Bloomfield and Melissa Burroughs-Pena, will cover a broad range of issues in the field of Global Cardiovascular Health. Topics covered in this issue include, but are not limited to Diagnosis and management of endomyocardial fibrosis; Chagas disease; Tuberculosis and the heart; Cardiovascular manifestations of human immunodeficiency virus infection; Improving global access to essential cardiovascular medicines; Innovative approaches to hypertension control in the community; Causes and treatment of infective endocarditis in developing countries; and Strategies for Patient Centered Blood Pressure Control in Low- and Middle income Countries, among others.

This issue of Cardiology Clinics, edited by Jae K. Oh, William Miranda, and Terrence D. Welch, will cover a broad range of topics related to Pericardial Disease. Subjects discussed include, but are not limited to: Anatomy and Physiology of the Pericardium; Imaging of the Pericardium, Acute and Recurrent Pericarditis; Tuberculous and Infectious Pericarditis; Pericardial Involvement in Systemic Diseases / Special Forms; Cardiac Tamponade; Constrictive Pericarditis; Effusive-constrictive Pericarditis; Surgical Management; Percutaneous Therapy in Pericardial Diseases; Congenital Abnormalities of the Pericardium, and Neoplastic Pericardial Disease.

This issue of Heart Failure Clinics, edited by Dr. Roberto Manfredini, will cover an array of topics related to Chronobiology and Cardiovascular Diseases. Topics include, but are not limited to Clock genes, metabolism and cardiovascular risk; Cardiac clocks and preclinical translation; Chronobiology of arterial blood pressure; Circadian periodicity of ischemic heart disease; Seasonal periodicity of ischemic heart disease and heart failure; Chronobiologic aspects of venous thromboembolism; Chronobiologic aspects of acute aortic diseases; Circaseptan periodicity of CV diseases; Gender and periodicity of CV disease; Chronopharmacology of CV drugs; Chronotherapy of Hypertension; and Chronoprevention of CV diseases.

Titles in the Pocket Tutor series give practical guidance on subjects that medical students and foundation doctors need help with ‘on the go’, at a highly-affordable price that puts them within reach of those rotating through modular courses or working on attachment.  Topics reflect information needs stemming from today’s integrated undergraduate and foundation courses: Common presentations Investigation options (e.g. ECG, imaging) Clinical and patient-orientated skills (e.g. examinations, history-taking) The highly-structured, bite-size content helps novices combat the ‘fear factor’ associated with day-to-day clinical training, and provides a detailed resource that students and junior doctors can carry in their pocket.   Key points New edition of the best-selling title that breaks down a complex and daunting subject using clearly-labelled, full-page ECG traces and concise but informative text Revised text and brand-new ECG traces bring the new edition fully up-to-date New chapters cover electrolyte and homeostatic disorders, and normal variants Logical, sequential content: relevant basic science, then a guide to understanding a normal ECG and the building blocks of an abnormal ECG, before describing clinical disorders

This issue of Heart Failure Clinics, edited by Drs. Wilbert Aronow and Ali Ahmed, will cover a wide array of topics related to Heart Failure in Older Adults. Subjects covered include, but are not limited to: Epidemiology, Pathophysiology, and Prognosis of Heart Failure in the Older Adult; DEFEAT Heart Failure: Clinical Manifestations, Diagnostic Assessment, and Etiology of Geriatric Heart Failure; Heart Failure with Preserved Ejection Fraction in the Older Adult; Heart Failure-Complicating Acute Myocardial Infarction; Interventional Therapies for Heart Failure in the Older Adult; Cardiac Resynchronization Therapy for Treatment of Heart Failure in the Older Adult; and Left Ventricular Assist Devices in Treatment of Heart Failure in the Older Adult, among others.