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This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects. Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especially preeclampsia, is a potent risk factor for chronic conditions such as cardiovascular disease, diabetes mellitus, kidney disease, and hypertension. The book is composed of seven parts including genetic background, pathology, pathophysiology, and the latest prediction and treatment of preeclampsia. Specific basic topics such as immunological maladaptation, placental adenosine signaling, and new prediction markers are also expounded by experts. Thus it benefits not only obstetricians, pediatricians, nephrologists, diabetologists, and cardiologists, but also immunologists, endocrinologists, geneticists, pathologists, biologists, and molecular biologists who are interested in the treatment of hypertension in pregnancy.
Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen is a timely addition to the growing body of literature in the field. Offering comprehensive coverage of cutting-edge imaging modalities, this book: Discusses MRI of the heart, blood vessels, lungs, breasts, diaphragm, liver, gallbladder, spleen, pancreas, adrenal glands, and gastrointestinal tract Explains how MRI can be used in vascular, posttraumatic, postsurgical, and computer-aided diagnostic (CAD) applications Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.
Acute Coronary Syndrome covers the spectrum of clinical conditions ranging from unstable angina to non-ST elevation myocardial infarction and ST elevation myocardial infarction. These life-threatening disorders are a major cause of emergency medical care, hospitalization and mortality. "Management of Acute Coronary Syndromes" is designed to provide busy clinicians with a comprehensive guide to the investigation, diagnosis and treatment of these syndromes. It encompasses the latest technologies, including the use of biomarkers and non-invasive imaging procedures.
For each condition, the reader is taken through all of the therapeutic options available; in each case the indications and contraindications are evaluated in the light of the latest clinical trials. Potential complications are dealt with in a similar fashion, permitting the reader to anticipate and manage problems as they arise. The authors also present evidence-based recommendations for long-term care of at-risk patients, encompassing pharmacologic therapies and lifestyle management.
The book concludes with a comprehensive collection of appendices that include treatment algorithms, risk scores and a summary of the latest management guidelines.
"Management of Acute Coronary Syndromes" is the most up to date and comprehensive evidence-based guide to managing acute coronary syndromes, in a compact and usable format. It will be of interest to busy specialist physicians in cardiovascular medicine, cardiac and vascular surgery, and critical care, as well as primary care physicians and hospitalists who care for patients with these syndromes.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A concise introduction to the principles and practice of point-of-care echocardiography for neonatologists and other clinicians caring for sick neonates Practical Neonatal Echocardiography is written to help clinicians develop the skills necessary to perform a high quality neonatal echocardiographic examination, evaluate cardiac function, and recognize abnormalities and defects. This unique text is based on an acclaimed course the authors have taught for the past sixteen years where they train neonatologists and other clinicians in the use of cardiac ultrasound for on-the-spot examination and diagnosis of neonatal patients. Features -Provides an introduction to the basic principles of echocardiography and the ultrasound scanners commonly used at pediatric cardiac centers-Neonatal cardiac anatomy is clearly described through use of 2-dimensional images and video clips-Chapters teach assessment of cardiac structure and function, central and peripheral blood flow, shunts, and pulmonary pressure-Myocardial dysfunction, heart failure, shock, hypotension, cardiomyopathy, cyanosis, pulmonary hypertension, and more are discussed in detail with multiple illustrative cases-Describes common features of ultrasound scanners and how to use them-Helps clinicians make informed choices about transducer selection, detailing particular advantages and disadvantages-Includes detailed descriptions of detecting abnormalities of cardiovascular function with and without congenital defects -Bolstered by more than 200 video clips (available at PracticalNeonatalEcho.com) that display real-life examples of normal vs. abnormal cardiac function in neonates
The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.
The ECG is one of the most commonly used investigations in contemporary medicine. Interpretation of the ECG can appear daunting, but it is actually relatively straightforward as long as a systematic approach is taken. Pocket ECGs for Nurses assists with this task by providing a detailed yet readable introduction to ECG interpretation, supplemented by clinical information about how to act based on its findings. The book begins by covering the basics of cardiac anatomy and physiology and how these relate to the ECG. It then guides nurses on how to perform a high-quality ECG recording, interpret it and make sense of common ECG abnormalities. The book also includes a guide to ambulatory and bedside monitoring as well as useful chapter summaries. This pocketbook is an essential reference for the non-specialist who needs to be able to record and perform a basic and safe interpretation of an ECG. Written in plain language with clear explanations, bullet lists and summaries throughout, this handy guide will benefit nurses as well as paramedics and other allied health professionals in recording and reading ECGs.
Recently reported experimental retrograde coronary venous techniques protect the acute- ly ischemic myocardium and appear to be a sound approach for temporary support of the severely jeopardized myocardi urn. The current brief report refers to important features of coronary venous interventions, describes apparent improvements, and discusses persist- ing difficulties in research and developmental evaluation of results. Taking note of the need of informing the scientific community, the recently established International Work- ing Group on Coronary Sinus Interventions (2) wishes to become a forum in which free discussion and criticism should be encouraged in the hope of stimulating research and the development and application of safe methods in the treatment of coronary disease. The eventual objective is to more fully define the limitations of applications and those ranges in which they can be applied without incurring any risks. Our ultimate goal is to maxi- mize the efficiency of applications while at the same time preventing the occurrence of undesirable side effects. References I. Beck CS (1949) Revascularization of the heart. Surgery 26: 82-88 2. Faxon D, Mohl W (1984) Summarizing statement of the panel of Working Groups. In: Mohl W, Wolner E, Glogar D (eds) The Coronary Sinus. SteinkopffVerlag, Darmstadt, pp 549-550 3. Meerbaum S, Lang TW, Osher JV et al (1976) Diastolic retroperfusion of acutely ischemic myo- cardium. Am J Cardiol 37: 558-98 4.
The endothelium is a thin mono-cellular layer which covers the inner surface of the blood vessels, separating the circulating blood from the tissues and also has the responsibility for uninterrupted maintenance of circulation to all the vital tissues. Endothelium is a very active organ, it works as a receptor-effector organ and responds to each physical or chemical stimulus with the release of the appropriate substance with which it may maintain vasomotor balance and vascular-tissue homeostasis. It has the property of producing, independently, both agonistic and antagonistic substances that help to keep homeostasis and its function is not only autocrine, but also paracrine and endocrine. In this way it modulates the vascular smooth muscle cells producing relaxation or contraction, and therefore vasodilatation or vasoconstriction. The vascular endothelium is vulnerable to maximum wear and tear due to its positioning and requires prompt regeneration of the cells. Whenever the imbalance between substances with vasodilating, antimitogenic, and antithrombogenic properties and substances with vasoconstricting, prothrombotic and proliferative characteristics takes place, it causes a pathological condition known as endothelial dysfunction. These substances intervenes in cell proliferation and migration, in leukocyte adhesion and activation and in immunological and inflammatory processes, further which is responsible for apoptosis of vascular endothelial cells resulting in overall endothelial dysfunction and vasculopathy. This book discusses, in further detail, the risk factors, and the role of endothelial dysfunction in cardiovascular diseases and therapeutic approaches to dealing with endothelial dysfunction.
Eureka - an innovative series for students that fully integrates core science, clinical medicine and surgery. With its engaging and authoritative text, featuring insightful clinical cases, graphic narratives, SBAs and a wealth of other learning tools, Eureka has everything students need to succeed in medicine and pass their exams. Eureka - content that reflects today's medical degree courses with their emphasis on: relevance and application of core science to clinical practice skills required to examine and communicate with patients integrated care across primary and acute care settings Eureka - 15 clinical titles, 5 science titles: Clinical titles - disease-based, clinical cases, system-specific core science Science titles - bedrock biomedical principles, clinical cases Series features across titles: Engaging clinical cases show how skilled clinician would work through a presentation, and put diseases and biomedical principles into patient context Innovative graphic narratives bring clinical cases to life, show how to approach difficult scenarios and convey the experience of being a patient Starter questions - stimulating answers to intriguing questions make learning fun Boxes highlight tips, tricks and key learning points Cardiovascular Medicine First principles chapter clearly explains the key concepts, processes and structures of the cardiovascular system Clinical essentials chapter provides an overview of the symptoms and signs of cardiovascular disease, relevant history and examination techniques, investigations and management options Disease-based chapters give concise descriptions of all major disorders, e.g. ischaemic heart disease, hypertension and heart failure, each chapter introduced by engaging clinical cases that feature unique graphic narratives Emergencies chapter covers the principles of immediate care in situations such as cardiac arrest and acute MI Integrated care chapter discusses strategies for the management of chronic conditions across primary and other care settings Self-Assessment - 80 multiple choice questions in clinical SBA format, in line with current exam format
What chemicals are poisonous to the heart and why are they toxic?
Trends indicate that the metabolic syndrome will become the leading risk factor for heart disease. Now more than ever you need an all-in-one reference that provides the tools and practical advice you need to: *Identify at-risk patients *Explain individual contributing factors *Aid in patient education and motivation *Direct comprehensive care and *Choose the most appropriate interventions Comprehensively revised to reflect leading-edge research and now organized to facilitate easy access to essential information and clinically-relevant guidance, Metabolic Syndrome and Cardiovascular Disease, 2e offers this and more. Not only will you receive a solid understanding of the pathophysiology underlying the metabolic syndrome and cardiovascular disease but also the rationale for today s most effective treatments. What s new? Filled with timely new content, this updated edition covers: * New discoveries that have changed our understanding of the pathogenesis and interrelationship of metabolic syndrome, cardiovascular disease (CHD), and type 2 diabetes mellitus (DM) * The relevance of mitochondria and telomeres * Sleep and its impact on cardiometabolic health * The pivotal interplay between insulin and forkhead transcriptionfactors * Calorie restriction research * Bariatric surgery experiences and outcomes In addition, each chapter includes essential information on comorbidities, interventions, and pharmacotherapeutic options an exclusive feature found only in the second edition!
As front line health care providers for children, pediatricians are entrusted with the responsibility for discovering early signs of heart diseases in this complex patient population. Especially in the newborn period, the presentation of pediatric heart disease is frequently obscure, and the consequences of these illnesses can be devastating if not caught early and managed correctly. This comprehensive, easy to understand book is a ready guide to acquiring the proficiency and confidence necessary to decipher the wide spectrum of disease presentations. Case scenarios give life to each chapter, with key images and illustrations reinforcing notable concepts. Special attention is given to the interpretation of chest radiographs and the role of echocardiography and catheterization. All chapters are dual authored by an academic cardiologist and a practicing general pediatrician, resulting in this book's elegant blend of medical authority, real life value, and fresh practical viewpoints. Heart Diseases in Children: A Pediatrician's Guide is divided into four sections. The first is an overall approach to heart diseases in children with ample discussion to diagnostic testing. The second and third sections cover the spectrum of congenital heart defects and acquired heart diseases. The fourth section prsents issues related to office cardiology. The book concludes with an extensive drug appendix. Significant and meaningful online complements, heart sounds and murmurs are available at www.pedcard.rush.edu providing practitioners the materials necessary to build confidence in their ausculatory skills. This unique book is a go-to resource for pediatricians, pediatric residents, family practitioners, medical students and nurses, conveying essential information for the diagnosis and treatment of pediatric heart diseases.
Echocardiography remains the most commonly used imaging technique to visualize the heart and great vessels, and this clinically oriented text by Drs. Scott D. Solomon, Justina C. Wu, and Linda D. Gillam helps you make the most of its diagnostic and prognostic potential for your patients. Part of the highly regarded Braunwald's family of cardiology references, Essential Echocardiography expertly covers basic principles of anatomy and physiology, the appearance of normal variants across a wide range of cardiovascular diseases, and the hands-on approaches necessary to acquire and interpret optimal echocardiographic images in the clinical setting. Abundant illustrations provide a superb visual learning experience both in print and online. Images convey clear, classic examples that represent decades of experience over multiple institutions, as well as recent advances in the field. More than 485 accompanying video clips mirror the images in the text, with easy-to-follow links from the figure citation to the video online. Each section includes one or two clinical cases that illustrate key concepts. Written by expert echocardiographers and sonographers who emphasize practical applications throughout the text, and superbly illustrated by physician-artist Dr. Bernard Bulwer. Ideal for anyone currently using or learning to use echocardiography, including cardiologists, cardiology fellows, sonographers, anesthesiologists, critical care physicians, emergency physicians, radiologists, residents, and medical students. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
The objective of this text is to synthesise the research based clinical treatment strategies that have been found to be most effective in the clinical management of heart failure as a disease. Incorporating recommendations from state of the art guidelines, the text will comprehensively address both in-patient management of acute exacerbations, and out-patient management to improve survival, quality of life, and functional status.
The editors are active members of the American Heart Association and influential councils on clinical cardiology and cardiovascular medicine, and have assembled a team of contributors prominent in the field of heart failure and transplantation. They aim, through this publication, to translate the findings of recent research into a practical clinical framework for physicians caring for patients on a daily basis.
Textbook of Pulmonary Vascular Diseases combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered.
An essential companion for both the aspiring and practising electrophysiologist, The EHRA Book of Pacemaker, ICD and CRT Troubleshooting assists device specialists in tackling both common and unusual situations that that they may encounter during daily practice. Taking a case-based approach, it examines pacemakers, implantable cardioverter defibrillators and cardiac resynchronisation therapy. Much more than just a technical manual of device algorithms, the cases help readers to consolidate their technical knowledge, and improve their reasoning and observation skills so they are able to tackle device troubleshooting with confidence. The 70 cases are arranged in three sections by increasing levels of difficulty to walk readers through all the skills and knowledge they need in an easy to use and structured format. Each case contains a short clinical description and a device tracing followed by a multiple choice question. Answers are supplied with detailed annotations of the tracing and an in-depth discussion of the case, highlighting practical hints and tips as well as providing an overview of the technical function of devices. A useful summary of principal device features and functions is also included. The EHRA Book of Pacemaker, ICD and CRT Troubleshooting is the perfect companion for electrophysiologists, cardiology trainees and technical consultants working with device patients as well as for those studying for the EHRA accreditation exam in cardiac pacing. This print edition of The EHRA Book of Pacemaker, ICD, and CRT Troubleshooting comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.
Our "fearfully and wonderfully made" bodies will one day wear out. But there are things we can do in the meantime to maximize our health and enjoy the years we've been given. Cardiovascular disease, heart disease, and stroke account for most of the deaths each year in the US and other developed countries. But you can often prevent these deadly illnesses if you control a key risk factor--the cholesterol levels in your blood. Physician and bestselling author Robert Lesslie describes effective ways for lowering your cholesterol and provides clear, expert advice on such key questions as What exactly is cholesterol? What are HDL, LDL, and triglycerides, and why is it important to know the difference between them? What roles do diet and exercise play in controlling your cholesterol levels? What are the benefits and dangers of cholesterol-lowering drugs? What alternative treatment options are available? Dr. Lesslie's realistic plan to lower your cholesterol will have you living healthier...and may even increase your chances for a longer, more vibrant life.
In the context of the most significant influx of migrants in European history, the objective of this book is to provide healthcare professionals with essential knowledge and skills to effectively treat and prevent cardiovascular diseases in ethnic minorities. Acknowledging that the scientific and cultural training of health professionals on the specific health needs of minority groups is still limited and likely biased, the book sheds light on the different health policies in European countries as well as epidemiologic data on cardiovascular events among migrants. In addition, it presents an in-depth analysis of potential ethnic-group-specific drivers of global cardiovascular risk within this new and challenging framework - as well as issues related to its prevention and treatment. The prevalence of hypertension, diabetes, chronic kidney disease, obesity, and metabolic syndrome is found to be higher among most minority groups than in the native population, yet their access to treatment and health services may be limited by cultural and language barriers. As health professionals are confronted with such intercultural challenges on a daily basis, specific training and dedicated publications are thus essential to accompany and foster a constructive development towards a pluralist and healthier society. This book addresses that need, offering a unique and revealing resource.
Hypertension: from basic research to clinical practice" contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.
The second edition of Clinical Arrhythmology provides a fresh, clear, and authoritative overview that will guide readers from a solid understanding of the mechanisms behind cardiac arrhythmias -- which is fundamental to their identification -- to diagnosis via electrocardiograms and other tools, to specific management options for each of the arrhythmias that cardiologists and other clinicians will encounter in clinical practice. * Organized in a clear, intuitive manner; introducing the reader to an understanding of the anatomical and electrophysiological bases of arrhythmias, then to a comprehensive review of how to diagnose the full range of rhythmic abnormalities, and then to a discussion of specific clinical syndromes in which arrhythmias play a part * Highly illustrated chapters ensure key concepts are simpler to understand * Detailed appendices provide quick reference values for diagnostic and therapeutic techniques, and pharmacotherapeutic agents, and Recommendations
This book aims to provide a comprehensive and clear review of the current knowledge of the relationship between obstructive sleep apnea (OSA) and cardiovascular and metabolic diseases, a subject of concern to a wide range of specialists and general practitioners. Separate chapters describe: the definition, symptoms and sequelae of OSA, and the diagnostic strategies and treatment options for adults with OSA according to the American Academy of Sleep Medicine; pathogenic mechanisms, by which OSA may contribute to the development and progression of cardiovascular and metabolic disorders, including inflammation, oxidative stress and thrombosis; links between OSA and obesity, alterations in glucose metabolism, metabolic syndrome and liver injury; relationships between OSA, endothelial dysfunction, autonomic dysfunction and cardiovascular disorders, and the results of studies investigating the effect of treatment for OSA on the concomitant cardiovascular disease. Each chapter summarizes the essential information and is illustrated by tables and figures, which will aid the readers in their understanding of the complex systemic interactions involved in this disease. Reviewed by internationally recognized experts, this publication will be of benefit to clinicians and scientists in the fields of pulmonology, cardiology, endocrinology and neurology as well as to sleep specialists and general practitioners.
This concise text presents best practices for all aspects of atrial fibrillation ablation as outlined in the new version of the VeniceChart International Consensus document, which is presented in conjunction with the biannual Venice Arrhythmias conference. In addition to discussing the latest in a-fib ablation research, this 2011 update covers all the key areas of therapy and patient management, including: * Techniques and technologies * Procedural endpoints * Patient management pre-, peri- and post-ablation * Prevention and treatment of complications * Definition of success and long-term results With contributions from the world's recognized thought leaders in this field, this book is a highly valuable source of information not only for specialists in electrophysiology, but also for general cardiologists, fellows in cardiology and others interested in this dynamic and increasingly important topic.
Cardiovascular disease refers to the class of diseases that involve the heart or blood vessels. While the term technically refers to any disease that affects the cardiovascular system, it is usually used to refer to those related to atherosclerosis. Chronic heart failure (CHF) has emerged as a major worldwide epidemic. This book gathers the latest research in cardiovascular disease with a focus on such topics as genetic risk factors for abdominal aortic aneurysms; blood pressure monitoring in biological time structures seasonal variations in ordinary living with perioperative case and salt restriction/weight reduction; genetics and perinatal milieus affecting saline preference in hypertensive rats; the influence of apolipoproteins in cardiovascular diseases; and novel effects of macrolide on MMP-related cardiovascular remodeling.
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