This issue of Cardiology Clinics, curated by Drs. Mark A. Creager and Stanislav Henkin, will explore topics related to Vascular Medicine. This issue is one of four selected each year by the series editorial board: Jamil A. Aboulhosn, David M. Shavelle, Terrence D. Welch, and Audrey H. Wu. Topics in this volume include, but are not limited to: Medical management of peripheral artery disease, Revascularization strategies for acute and chronic limb ischemia, Acute aortic syndromes, Thoracic aortic aneurysms, Abdominal aortic and visceral artery aneurysms, Renal and mesenteric artery disease, Extracranial carotid artery disease, Venous thromboembolism, Varicose veins and chronic venous insufficiency, Raynaud phenomenon and other vasospastic disorders.

The thoroughly updated second edition of this key textbook provides an authoritative discussion of cardiovascular disease for the practicing primary care clinician. It examines a variety of disease states with emphasis on risk factors, risk estimation, and established cardiac disease. The book also explores the co-morbid conditions that surround cardiovascular disease. It includes key points, algorithms, case studies, recommendations on evidence-based practice, and summary boxes. A key resource for the busy practitioner, the Second Edition of Comprehensive Cardiovascular Medicine in the Primary Care Setting is designed to give residents, fellows, and primary care physicians the skills to confidently perform assessments, initiate and maintain efficacious therapy, and know when a referral to a cardiologist is advisable.

The goal of Endovascular Skills: Guidewire and Catheter Skills for Endovascular Surgery has always been to provide a "step-by-step" approach to techniques and procedures that comprise one of the most exciting and rapidly developing specialties in medicine today: minimally invasive management of vascular disease. Endovascular technique has gone from being a novelty to a mainstay of vascular care and this edition of Endovascular Skills has been revised and expanded to reflect these changes. This book serves as a "how-to" guide for endovascular intervention and aims to assist clinicians in the development and refinement of skills that are now essential to vascular practice. The book introduces readers to strategy, vascular access, guidewire-catheter handling, and arteriography in a multitude of vascular beds. The knowledge base builds as the text progresses in much the same manner that the skill of the professional builds as experience is gained by performing more complex cases and managing complicated patterns of disease. The chapters progress to all aspects of endovascular therapy, including sheath access, balloon angioplasty, stents, and other treatment modalities.

Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.

This issue of Heart Failure Clinics, guest edited by Drs. Giuseppe Pacileo, Daniele Masarone, Francesco Grigioni and Luciano Potena, will cover key topics in Advanced Heart Failure: From Pathophysiology to Clinical Management. This issue is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue include (but are not limited to): Pathophysiology of advanced heart failure: what I need to know for clinical management?, Advanced heart failure: definition, epidemiology and clinical course, Echocardiography in advanced heart failure: beyond diagnosis, Disease modifier drugs in patients with advanced heart failure: How to optimize their use?, Congestion in patients with advanced heart failure: Assessment and treatment, Inotropes in patients with advanced heart failure: Not only palliative care, Cardiac resynchronization therapy and cardiac contractility modulation in patients with advanced heart failure: How to select the right candidate?, Mitral and tricuspid valves percutaneous repair in patients with advanced heart failure: Panacea, or Pandora's box?, Left ventricular assist device: Indication, timing and management, Listing criteria for heart transplant: Role of cardiopulmonary exercise test and of prognostic scores, Right heart catheterization in patients with advanced heart failure: when to perform, how to interpreter?, Advanced heart failure in special population: Cardiomyopathies, Advanced heart failure in special population: Pediatric age, Advanced heart failure in special population: Heart failure with preserved ejection fraction and Treatment of advanced heart failure: What future holds?. Provides in-depth, clinical reviews on advanced heart failure, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.

Advances in structural heart disease (SHD) is occurring at a rapid rate, and the Mayo Clinic is at the forefront of developing procedural techniques in this fast-changing field. Handbook of Structural Heart Interventions provides practical, focused coverage of SHD, bringing you up to date with today's evidence-based techniques and approaches for common and uncommon SHD procedures. Ideal for both SHD trainees and established practitioners, attendings, and fellows in interventional cardiology, this easy-to-use handbook is a unique educational and clinical resource in a quickly expanding field. Uses a consistent format for procedures, clearly guiding you through the scope of the problem, procedure/technique, and outcomes. Employs a "building blocks" approach pioneered at Mayo as an effective training method for procedural learning. Includes training tips and pitfalls from leading structural heart authorities. Contains 550 full-color illustrations, including anatomy and step-by-step procedures. Features separate sections on aortic valve interventions, mitral valve interventions, ventricular septal interventions, tricuspid valves, pulmonary valves, ACHD interventions, and miscellaneous/variable anatomic positions. Covers key procedures such as TAVR; valvuloplasty, valve-in-valve, and valve-in-ring; left atrial appendage closure; VSD closure, paravalvular leak closure, and more. Provides access to 20 videos of interventional procedures, including PFO and ASD closure, assessment of patients for MitraClip, and aortic coarctation stenting. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

The only reference wholly dedicated to this complex topic, Diagnosis and Treatment of Mitral Valve Disease: A Multidisciplinary Approach provides authoritative, must-have information on the disease processes affecting the mitral valve, interpretation of diagnostic studies, and medical, transcatheter, and surgical treatments needed for mitral valve repair. Using a multidisciplinary approach, Drs. Scott Goldman and William Gray oversee a "who's who" team of contributing authors who offer a holistic view of the modern treatment of mitral valve disease for today's cardiac surgeons, cardiologists, and other cardiac team members. Includes foundational chapters on anatomy and pathophysiology of the mitral valve-critically important topics when treating multiple complex and highly dynamic structures that function as a single unit. Covers diagnostic tools, medical treatments, surgical therapies, and transcatheter therapies, and provides tips for developing a successful mitral valve program (with baseline thresholds, common pitfalls, and a checklist for hospitals). Uses an accessible, quick-reference format that features takeaway chapter openers, bulleted key points, end-of-chapter summaries, a common nomenclature and glossary of terms, key references, and ample line drawings, photographs, tables, charts, and graphs throughout. Incorporates the essential role of imaging in structural transcatheter interventions, including echocardiography and transcatheter edge-to-edge repair (TEER), and their uses in diagnostic work-up, procedural planning, intra-procedural guidance, and follow-up. Features dozens of procedural videos, including transthoracic echocardiogram; cardiac MRI for mitral regurgitation; transcatheter mitral valve repair; transcatheter valvuloplasty; percutaneous mitral valve interventions; MitraClipT positioning; and many more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. * Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy * Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice * Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease * New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease * Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Suneet Mittal and David Slotwiner,, is dedicated to Device-Based Arrhythmia Monitoring. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to: Implantable loop recorders, Permanent pacemakers and implantable cardioverter defibrillators, Heart failure monitoring, Remote programming and cybersecurity concerns, Models for remote monitoring, Data management and integration with EMR systems, Screening for atrial fibrillation and The role of artificial intelligence in arrhythmia monitoring.

This important title brings together a distinguished panel of thought-leaders, known for their insights into the development and application of minimally-invasive surgical and endovascular techniques, to provide a comprehensive and discerning compendium of our most current knowledge and state-of-the-art procedures in the management of cerebral vascular diseases. Written in a style that is accessible to students and experienced practitioners alike, the book covers all the important recent advances that have reshaped the field in dramatic ways. Emphasizing how surgical and endovascular techniques are complementary, the volume includes illuminating chapters on the nexus of endovascular and conventional "open" cerebrovascular surgery, including patient assessment and practice in a hybrid operating environment, utilizing the best methods to achieve optimal outcomes. A major addition to the clinical literature, Management of Cerebrovascular Disorders: A Comprehensive, Multidisciplinary Approach will be of significant interest to neurosurgeons, neurologists, neuroradiologists, neurointensivists, students, residents, fellows, and specialized attending physicians.

This book, written by premier authors in the field of OCT intravascular imaging, covers the best practices for using OCT to provide high resolution cross-sectional viewing for atherosclerotic plaque assessment, stent strut coverage and apposition, assessment in stent restenosis evaluation, and PCI guide and optimization. Fully illustrated thorughout in a handy, cath-lab side handbook supplemented by online movie clips, OCT Made Easy includes case studies, angiography, CT correlations, and simple techniques for getting the best image.

The second edition of this critical text features heavily revised chapters detailing how to approach the anesthetic and perioperative management of adult and pediatric patients with congenital heart disease. Initially, a broad overview of relevant concepts in pediatric cardiovascular embryology, physiology, and pharmacology is provided. Subsequently, relevant diagnostic approaches including the use of three-dimensional modeling in surgical planning and preoperative considerations are described. The intraoperative management of a wide range of specific lesions is discussed, with full descriptions of anesthesia plans and the appropriate diagnostic methods and surgical interventions. New topics detailed include the use of hybrid techniques and applications of electrophysiology in patients with congenital heart disease. Postoperative care and potential future approaches are also addressed. Congenital Heart Disease in Pediatric and Adult Patients: Anesthetic and Perioperative Management provide a comprehensive, up-to-date overview of the care of the pediatric patient undergoing cardiac surgery and anesthesia. It is therefore of interest to all practicing and trainee medical professionals who encounter these patients in their day-to-day practice.

150 ECG Cases presents clinical problems in the shape of simple case histories together with the relevant ECG. Detailed answers concentrate on the clinical interpretation of the results and give advice on what to do. The book can be used as a standalone method of practising ECG interpretation, and even with the most difficult ECGs a beginner will be able to make an accurate description of the trace and will be guided towards the key aspects of the interpretation. The unique page size allows presentation of 12-lead ECGs across a single page for clarity. Several of the cases incorporate chest X-rays and coronary angiograms illustrating the appearances that are associated with various cardiac conditions. All the cases are graded in difficulty and are cross-referenced to the new editions of ECG Made Easy and ECG Made Practical for further information. This Fifth Edition has been re-ordered into two parts: Part 1 Everyday ECGs: The 75 ECGs in this section are examples of those commonly seen in clinical practice. There are several examples of the most important abnormalities, together with examples of common variations of normality. Part 2 More Challenging ECGs: The 75 ECGs in this section are more demanding and include ECG patterns seen less often in clinical practice. For this Fifth Edition over fifteen per cent new ECGs have been included, mainly to provide clearer examples, though the book deliberately retains some technically poor records to maintain a 'real-world' perspective

This unique volume provides the latest information on secondary metabolites obtained from selected organisms (plants or microorganisms) that have beneficial effects in the treatment of cardiovascular diseases and an ability to offer protection against their progress. A detailed description of their source, chemistry and mechanism of action is provided, together with results of clinical studies. Here, a clear connection is made between chemical structures, in vitro studies and their clinical significance.The topic is extensive and the audience gains an understanding of the medicinal applications of these groups of secondary metabolites that have the potential to improve cardiovascular health. Features: The latest information on secondary metabolites with beneficial effects in the treatment of cardiovascular diseases. Written by an outstanding team of authors, their work provides new insights into the beneficial effects of different components present in well known plant products, evidencing their impressive cardiovascular effects. This volume discusses novel targets to screen for new drugs and the need for data obtained from clinical studies using natural products in order to better analyze the significance of in vitro experimental data. Here the reader will find a unique and timely volume with an international flavor. This book describes the source, chemistry and mechanism of action of natural products with the potential to improve cardiovascular health.

In this issue of Cardiology Clinics, guest editor Dr. Matthew W. Martinez brings his considerable expertise to Sports Cardiology. Top experts in the field cover key topics such as preparticipation sports clearance from a pediatric cardiology perspective; evaluation and treatment of an athlete runner with hypertension; ectopy and the athlete: observation, medication, or intervention; exercise and the HCM guidelines; ECG criteria for athletes; and more. Contains 13 relevant, practice-oriented topics including genetic cardiomyopathies: avoid these common pitfalls; devices and athletics: how to decide who can play; the tactical athlete: definitions, assessment, and management of symptoms; the athlete and vascular conditions: don't miss these important conditions; myocarditis and exercise: when and how to return to sports; and more. Provides in-depth clinical reviews on sports cardiology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In recent years, there have been no books published on paediatric cardiac pathology despite enormous developments in genetics, a marked explosion of paediatric transplant programmes, surges in knowledge of fetal cardiac pathology and understanding of congenital heart disease, and the emergence of a flourishing cardiac imaging discipline. This book will be the first unified and comprehensive source of reference for childhood heart disease, covering the full field of paediatric cardiac pathology, in one volume. Comprising the twenty-five year experience of a single pathologist, the full spectrum of the pathology of heart disease, from the fetus to the adult, is uniquely presented here. Richly illustrated, with over 800 colour photographs, general and paediatric pathologists alike will be able to examine the microscopic features of the conditions described, with a specific focus on metabolic disease for practitioners worldwide.

Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology.

A practical resource covering both elective and emergency procedures for the practicing vascular and endovascular clinician This book provides medical professionals (vascular surgeons, interventional cardiologists, interventional radiologists, endovascular neurologists, vascular medicine specialists) with a reference guide to the most common and accepted approach to endovascular management of peripheral vascular disease. It also addresses urgent interventions in the acute setting of the various vascular beds, and covers emerging areas such as stroke intervention and endovascular treatment of pulmonary embolism and vascular trauma. Edited by a multidisciplinary team, Endovascular Interventions offers in-depth coverage of the field in seven parts: Overview; Supra-Aortic Intervention in High Risk Patients: Innominate, Subclavian, Carotid, Vertebral and Intracranial Interventions; Interventions of the Aorta; Renal and Mesenteric Interventions; Lower Extremity Interventions; Venous Disease; and Vascular Trauma. Each section covers the technical aspects of the procedures as well as the fundamental clinical aspects which are necessary in the evaluation of patients considered for interventions. Chapters feature illustrations, case studies, key learning points, equipment lists, and sample questions and answers which can be used for Board exam practice. Practical review of vascular and endovascular medicine covering both elective and emergency procedures Illustrated, templated chapters provide rapid answers to questions and include case studies, key learning points, and equipment lists Includes sample questions and answers that are handy for Board exam practice Edited by multidisciplinary experts Endovascular Interventions is an excellent review book for all practicing and aspiring vascular and endovascular specialists.

Grossman & Baim's Handbook of Cardiac Catherization

In this issue of Heart Failure Clinics, guest editors Drs. Alberto M. Marra, Pietro Ameri, and Alexander E. Sherman bring their considerable expertise to Challenges in Pulmonary Hypertension. Top experts in the field cover key topics such as gender aspects in pulmonary hypertension; PAH in connective tissue diseases beyond systemic sclerosis; genetic background of high altitude pulmonary edema; oxygen therapy in pulmonary vascular disease; and more. Contains 13 relevant, practice-oriented topics including rare forms of pulmonary hypertension; management of SARS-CoV-2 infection and COVID-19 in patients with pulmonary arterial hypertension; anabolic deficiency in pulmonary arterial hypertension; anticoagulation in pulmonary hypertension; and more. Provides in-depth clinical reviews on challenges in pulmonary hypertension, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Fermin C. Garcia, Luis C. Saenz, and Pasquale Santangeli, is dedicated to Intracardiac Echo Imaging in Atrial and Ventricular Arrhythmia Ablation. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to: How to use intracardiac echography to recognize normal cardiac anatomy, Intracardiac echography to guide catheter ablation of ventricular arrhythmias in ischemic cardiomyopathy, Intracardiac echography to guide ablation of parahisian arrhythmias, Utility of ICE to guide transseptal catheterization for different EP procedures, Intracardiac echography to guide catheter ablation of atrial fibrillation, Role of intracardiac echography for transcatheter occlusion of left atrial appendage, Intracardiac echography to guide catheter ablation of idiopathic ventricular arrythmias, Intracardiac echography to guide catheter ablation of ventricular arrhythmias in non-ischemic cardiomyopathy, Intracardiac echography to guide mapping and ablation of arrhythmias in congenital heart disease patients, Prevention and early recognition of complications during catheter ablation by Intracardiac echography, Intracardiac echography to evaluate radiofrequency lesion creation and Image integration using intracardiac echography and 3-D reconstruction for mapping and ablation of atrial and ventricular arrhythmias.

This issue of Heart Failure Clinics, guest edited by Geu-Ru Hong, will cover key topics in Heart Failure with Preserved Ejection Fraction. This issue is one of four selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: Current Trends and Outcomes of Heart Failure with Preserved Ejection Fraction, Pathogenesis and Phenotypes of Heart Failure with Preserved Ejection Fraction, Hypertension and Heart Failure with Preserved Ejection Fraction, Obesity in Heart Failure with Preserved Ejection Fraction, Noninvasive Hemodynamic Evaluation at rest in Heart Failure with Preserved Ejection Fraction, Clinical Phenogroups in HeartFailure With Preserved Ejection Fraction and response to therapy, among others.