This book provides practical guidelines to chemical engineers, plant managers, maintenance engineers, and senior managements in modern chemical processing facilities. It provides guidelines to the readers for operational competencies such as hazard identification (HAZID), hazard operability studies (HAZOP), avoiding mistakes in plant facilities to ensure safety, compliance with various statutory rules and regulations; and management of human resources through improved working conditions, provision of safety equipment etc. It further presents technical information on pressure vessels, design of piping and selection of pumping systems, materials for construction and lining of process units operating at high temperature and corrosive conditions, and criteria for selection of different methods for heating of process units. In addition to its application to existing operations, the book includes information on expansion, diversification, and modernization of facilities and guidelines for revival of old and idle plants. Finally, the authors discuss various safety issues, controlling cost of production, and sustainability topics such as planning and implementing co-generation of steam and power, environmental pollution control for chemical plants and safe disposal of hazardous wastes.

Peptidomimetics have found wide application as bioavailable, and often potent mimetics of natural peptides. They form the basis of important classes of enzyme inhibitors, they act as receptor agonists and antagonists, and they have even been used to mimic DNA structure. Recent advances in the use of solid-phase organic synthesis have paved the way for the preparation of libraries of these structures to allow the rapid optimization of theri biological properties and hence therapeutic potential. We are also beginning to gain a greater understanding of the structural features of this class of compounds that influence their ability to permeate membranes, and their rate of clearance and metabolism. This volume brings together many of these critical issues by highlighting recent advances in a number of core peptidomimetic-based research.

A thorough history. Lactic acid's chemistry has posed problems that required the large-scale preparation of the acid for study; its manufacture is a complicated process involving many subdisciplines of the science of chemistry; its use encompasses many fields of industrial activity and important asp

This book provides an overview of the use of nanoparticles, carbon-nanotubes, liposomes, and nanopatterned flat surfaces for specific biomedical applications. This book explains the chemical and physical properties of the surface of these materials that allow their use in diagnosis, biosensing and bioimaging devices, drug delivery systems, and bone substitute implants. The toxicology of these particles is also discussed in the light of a new field referred to as nanotoxicology in this book. This book will be useful for engineers, researchers and industry professionals primarily in the fields of polymer science and engineering, materials science, surface science, nanocatalysis, biotechnology and biomedicine.

This book presents recent developments and future scopes of glassy systems, such as their electrical and optical properties, use as electrodes, photonics devices, battery applications and others, which are of great interest for material scientists and professionals. Each chapter is designed to increase coherence, containing examples and question sets as exercises for in-depth understanding of the text. It provides a valuable resource for researchers, professionals and students in the area of material research especially on Li-doped glasses.

This book, as the fourth volume, continues on ultra-high temperature materials with melting (sublimation or decomposition) points around or over 2500 DegreesC. In this quality the book has over-branched cross-links with the sections and tables of the previous Volumes I-III. Similarly to Volumes I-III, the book includes a thorough treatment of the physical and chemical properties of ultra-high temperature materials, namely such as W semi- and monocarbides, and continues the description of refractory carbides, which was begun from Volume II of the series. The book will be of interest to researchers, engineers, postgraduate, graduate and undergraduate students alike. The readers are provided with the full qualitative and quantitative assessment, which is based on the latest updates in the field of fundamental physics and chemistry, nanotechnology, materials science, design and engineering.

This book explores the most important processing steps of proteomics data analysis and presents practical guidelines, as well as software tools, that are both user-friendly and state-of-the-art in chemo- and biostatistics. Beginning with methods to control the false discovery rate (FDR), the volume continues with chapters devoted to software suites for constructing quantitation data tables, missing value related issues, differential analysis software, and more. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and implementation advice that leads to successful results. Authoritative and practical, Statistical Analysis of Proteomic Data: Methods and Tools serves as an ideal guide for proteomics researchers looking to extract the best of their data with state-of-the art tools while also deepening their understanding of data analysis.

This second edition volume expands on the previous edition with discussions of recently developed techniques that use RNA scaffolds as molecular tools. These latest methods are used in the fields of molecular biology, cellular biology, nanotechnology, and structural biology. The chapters in this book cover topics such as RNA footprinting using small chemical reagents; using tRNA scaffolds to assist RNA crystallization; identification of RNA-binding proteins associated to RNA structural elements; and synthetic biology medicine and bacteria-based cancer therapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, RNA Scaffolds: Methods and Protocols, Second Edition is a valuable resource that explores the fascinating uses of RNA in these different areas, and will inspire experts and novice researchers to further study this developing field.

On August 18, 1977 a special 'Soddy Session' was held at the Fifteenth International Congress of the History of Science, Edinburgh, Scotland, with Dr. Thaddeus J. Trenn as Symposium Chairman. This session was organized to commemorate the lOOth anniversary of the birth of Fre derick Soddy (born September 2, 1877, Eastbourne, England; died September 22, 1956, Brighton, England), who was awarded the 1921 Nobel Prize in Chemistry 'for his contributions to our knowledge of the chemistry of radioactive substances, and his investigations into the origin and nature of isotopes'. Soddy taught and/or carried out research at Oxford University (where he was Lee's Professor of Chemistry), McGill University (where he and Sir Ernest Rutherford proposed the disintegration theory of radioactivity), University College, London (where he and Sir William Ramsay demonstrated natural transmuta tion), Glasgow University (where he formulated his displacement law and concept of isotopes), llnd Aberdeen University. In addition to his contributions to radiochemistry, he proposed a number of controversial economic, social, and political theories. The present volume contains the eight lectures presented at the symposium, two additional papers written especially for this volume (Kauffman, Chapter 4 and Krivomazov, Chapter 6), a paper on Soddy's economic thought (Daly, Chapter 11), and three selections from Soddy's works. Furthermore, an introductory account of Soddy's life and work by Thaddeus J. Trenn as well as a Soddy chronology, and name and subject indexes compiled by the editor are provided."

This volume provides a practical guide providing step-by-step protocol to explore vaccines for farm and companion animals, as well as for fish and insects. Divided into three volumes, Volume 2: Vaccines for Veterinary Diseases guides readers through veterinary vaccines, vaccines for poultry, vaccines for farm animals, and vaccines for veterinary parasites. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 2: Vaccines for Veterinary Diseases aims to be a useful practical guide to researchers to help further their study in this field.

This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.

This book is the ultimate assembly of recent research activities on molecular architectonics and nanoarchitectonics by authors who are worldwide experts. The book proposes new ways of creating functional materials at the nano level using the concepts of molecular architectonics and nanoarchitectonics, which are expected to be the next-generation approaches beyond conventional nanotechnology. All the contents are categorized by types of materials, organic materials, biomaterials, and nanomaterials. For that reason, non-specialists including graduate and undergraduate students can start reading the book from any points they would like. Cutting-edge trends in nanotechnology and material sciences are easily visible in the contents of the book, which is highly useful for both students and experimental materials scientists.

The matrix isolation (MI) method has now been used for nearly thirty years. During this period it has been actively developed and the range of problems tackled greatly extended. Originally it was used for studies of transient species involv ing vibrational, electronic and ESR spectroscopy. Nowadays the study of transient species forms a comparatively small part of HI work since it has been amply demonstrated that very fruitful information can be obtained of the structure and interactions of stable molecules and their aggregates. In addition to the s ectroscopic methods mentioned above the MI technique is nowadays a standard method in research based on vibrational relaxation, luminescence, Mossbauer, magnetic circular dichroism, pulsed NMR and photoelectron spectroscopy. The matrix isolation technique affords considerable advantages over more conventional methods in most applications of spectroscopy. Areas where the technique has been widely applied, or shows great potential, include: metal atom chemistry, and its relation to surface chemistry, high temperature inorganic species, transition metal complexes, interstellar species, free radicals and unstable molecules, conformational studies, molecular com plexes, and intermolecular forces."

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.

Originally published in 1913. PREFACE: CONSIDERING the importance of the coal tar industry at the present day, it is surprising how few practical text-books there are on this subject. I feel, therefore, that no apology is needed for offering to students, gasworks and tarworks managers and others interested in this industry, and in chemical technology, a short treatise dealing in a practical manner with the distillation of coal tar and the working up of its chief products. In order that this book could be produced at a moderate price it has been necessary to deal with the plant and processes used in the working up of the chief products obtained by the distillation of coal tar in a more or less brief manner. Special attention has been given to the plant used for, and the process of distillation of tar, as this portion of the industry is the most important, there being many works in which tar is submitted to distillation, or a partial distillation, for special purposes, and the distillates sold to other distillers for working up. As far as possible I have adhered to descriptions of plant and processes with which I have had a practical acquaintance, and I have drawn many of the illustrations in a diagrammatic form in order to render them more easily understood. With reference to the figures relating to change over points, temperatures used, amounts of distillates obtained and so on, those given have been employed in actual practice at one time or another, but theymust notbe taken as guides, as coaltar and coal tar distillates, etc., are liable to variation. My thanks are due to the firms of Messrs. Thos. Broadbent Sons, Ltd., S. H. Johnson Co., Ltd., and Robert Middleton, for their kindnessin lending me electros with which to illustrate Chapter xiv. Also to Mr.W. R. Ball for the great assistance he has given me in reading over much of the manuscript. Thanks are also due tomy wife for the assistance she has given me in the preparation of the index, and the correction of the proof sheets. Hull, 1913. vii ARTHUR R. WARNES. Contents include: CHAPTER I COALTAR ITSCOMPOSITION EFFECTOFNATURE OFRAWMATERIAL AND HEAT OF CARBONIZATION ON PHYSICAL PROPERTIES AND CHEMICAL COMPOSITION OF TAR RESULTS OF PRACTICAL DIS- TILLATIONS . CHAPTER II How TAR is RECEIVED FROM GASWORKS TAR TIPS STORAGE OF TAR CONSTRUCTION OFSTORAGETANKS PUMPS CHAPTER III PLANT USED IN THE DISTILLATION OF TAR. . . . .10 Tar stills metals used in their construction design fittings building of still safety contrivances swan-neck steam pipes charge block dipping cock -manhole and lid tail pipe and pitch cock thermometer. CHAPTER IV PLANT USED IN THE DISTILLATION OF TAR continued . . 25 Still foundations settling ashpits fireplaces curtain arch flues burners for gas firing gas sewer coal v. gas firing. CHAPTER V PLANT USED IN THE DISTILLATION OF TAR continued ., 33 Preheaters corrosion of preheater coils advantage of preheaters condensing coils corrosion of condensing coils condenser coil tanks steam coils collecting and dividing boxes foul gas mains methods of dealing with foul gases methods of running distil- lates to receivers cocks types of receivers steam valves pitch coolers French weir cooler pitch gutters pitch bays emergency pumps. DISTILLATION or COAL TAR .. . CHAPTER VI PAGE . . . . . 48 Charging preheater and still commencing the distillation crude naphtha and ammonia water stage light oil stage carbolicoil stage creosote stage anthracene oil or green oil stage- introduction of steam Wells oil method of testing used by stillmen examination of safety valves, etc...

This book features selected papers presented at the 2021 International Conference on Development and Application of Carbon Nanomaterials in Energetic Materials. It discusses the latest progress in the field of advance carbon nanomaterials in energetic materials; including the structural design, theoretical calculation, synthesis, properties, and applications of carbon materials. It also presents the new technology and applications of advanced carbon nanomaterials in energetic materials. It can be used as a reference book for researchers in energetic materials and related fields. It is also be useful for undergraduates and postgraduates studying these topics.

This third edition provides new and updated chapters detailing a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins with their natural ligands, drugs or other binding partners. Chapters detail natural substrates, potential drug leads, quantitative understanding of the mechanism of interaction, and different techniques. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Protein Ligand Interactions: Methods and Applications, Third Edition serves as an ideal guide for researchers new to the field of biophysical characterization of protein interactions.

This volume brings together cutting-edge laboratory protocols to characterize the novel fluorescent proteins (FPs) and approaches based on fluorescent proteins that aim to answer some of the key cell biological questions. The book covers topics ranging from the database of fluorescent proteins to their characterization and adaptation to a wide range of biological systems. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Fluorescent Proteins: Methods and Protocols serves as an ideal guide for students and academicians enthusiastic about the recent progress in the practical application of fluorescent protein technology.

This detailed volume explores the most recent methodologies and applications of stable isotope labeling by amino acids in cell culture (SILAC). With the development of new technologies in the field of mass spectrometry and bioinformatics, SILAC-based methods have become the first tool of choice in quantitative proteomics either on its own or in combination with other more recently developed approaches, which is elucidated in the chapters of this book. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, SILAC: Methods and Protocols serves as an ideal guide for researchers working in the area of functional proteomics and other aspects of protein science.

The field of electromagnetic sensitivity is the new epidemic of the 21st century, and can cause disease of the automatic nerve system in any part of the body. This is as a result of chemical sensitivity, in which over 80,000 chemicals are involved, resulting in innumerable combinations. A cursory understanding of the combinations can help clinicians partially understand the associated problems and thus help in the diagnosis and treatment of electromagnetic sensitivities. But a basic understanding of environmentally induced illness and healing must first be understood by the clinicians before diseases occur such as cardiac arrhythmia, muscle spasms, and nerve pain. Key Features: Describes how an understanding of the vast combinations of electrical and chemical sensitivities will help in the diagnosis and treatment of electromagnetic sensitivities Reveals the complexity and multi-faceted presentation often seen in chemical sensitivity and chronic degenerative disease cases Provides information backed up by rigorous scientific data including hundreds of tables and figures as online resources Features a Dedication to Robert Becker, MD, an orthopedic surgeon who was one of the first clinicians to recognize the significance of EMF in medicine and surgery, and also to his assistant Andrew Marino, PhD, who helped develop the basic science of orthopedic electromagnet healing

Rabies is one of the oldest known pathogens, is incurable, and has the highest fatality rate of all infectious diseases. The Americas is the only region with bat rabies virus, including vampire bat rabies. The region is rich in cultural references and notable for many discoveries in the field, including the current vaccine potency test, diagnostic assay, conception of oral vaccines for wildlife, the first human survivor and the first successful canine rabies program executed at a broad level. Rabies remains the most important viral zoonosis, with tens of thousands of human fatalities and tens of millions of exposures annually, which can be used to model for other pathogens, such as COVID-19. There is an international effort to eliminate human rabies caused by dogs over the next decade, and the Americas represent the primary region with the greatest proof-of-concept evidence to accomplish this goal.  This two-volume set addresses the medical history and modern results of rabies in countries throughout the Americas, including the implications of and on cultural, economic, sociological, and research developments in the region. Volume I presents an overview of concepts critical to the study of rabies in the region, including evolutionary aspects, reservoir ecology and control, elimination efforts, vaccine development, and disease hallmarks and progression. It also analyzes the long-term cultural, social, and economic impacts of the disease in the Americas. 

Water is a paramount determinant of quality of life. The WHO experts believe that the sickness and death rates of the world population could be reduced by 75% by maintaining good quality of drinking water. That is why thirty-one leading scientists and specialists from fifteen countries gathered in November 2003 at the NATO Advanced Research Workshop (ARW) on "Modern Tools and Methods of Water Treatment for Improving Living Standards" in Dnepropetrovsk, Ukraine, to discuss the scientific concepts and practical means for the solution of the complex social, economic and ecological problems associated with water purification, consumption, conservation, and protection. All this is covered in this book of proceedings of the NATO ARW.

This book contains four parts. In Part 1, the readers will find recent advances in drinking water treatment in the United States, biological control in water-cooling towers, analytical control of drinking water quality, and the use of radionuclides for monitoring global contamination. In Part 2, some innovative methods and tools, such as electrochemically-stimulated sorption and sorption-membrane methods, a bubble-extraction method, fibroid sorbents, in-situ oxygen curtain technology, use of ion-exchange membranes, electrochemically-generated silver and copper ions and colloidal gold for water purification and post-purification are presented. In Part 3, recent studies into the treatment of wastewaters could be found. Among them: water reclamation and recycling in Danish industry, biocide polymers as a new opportunity in water treatment, optimization of galvanic wastewater treatment processes, efficiency of nitrification and denitrification processes inwastewater treatment plants, electrochemical processes for wastewater purification employing fluidized beds of particles, cold plasma as a new tool for purification of wastewater from chemical contaminants, bacteria and viruses. In Part 4, examples of management of water resources in the United Kingdom, Bulgaria, Poland, Croatia, and Romania using a variety of case studies are presented. Also, the important issue of industry-university cooperation for postgraduate education and training in the water treatment area is discussed.

We believe that this book will be helpful to the international community of scientists, specialists and students dealing with water treatment, purification, conservation and protection.

This edited book focuses on processing, properties, and applications of bast fiber and its composites written by renowned researchers and academicians. The contents focus on properties such as rheological and dielectric of bast fiber composites. It also discusses its dynamic mechanical analysis, thermal stability of polymer composites reinforced with bast fibers, and water absorption behavior of bast fiber incorporated polymer composites. This book will be beneficial to both the industry and academia as it highlights possible avenues of future research.

This book interprets the economic benefits and social benefits brought about by zero waste. Beginning with the general history of waste, its mechanism and different categories, this book first explores waste management and resourcing technology around the world nowadays. It then elaborates on the concept and practices of zero waste, discussing about the relationship between zero waste and eco-design, and about relative international standards. At last, it points out that zero waste could be the pathway from linear economy to circular economy, backed up by theories and practices. This book offers a clear direction for companies and organizations about environment. It can also be used as a sustainable development strategy handbook for executives in companies and organizations.