Covers the State of the Art in Superfluidity and Superconductivity Superfluid States of Matter addresses the phenomenon of superfluidity/superconductivity through an emergent, topologically protected constant of motion and covers topics developed over the past 20 years. The approach is based on the idea of separating universal classical-field superfluid properties of matter from the underlying system's "quanta." The text begins by deriving the general physical principles behind superfluidity/superconductivity within the classical-field framework and provides a deep understanding of all key aspects in terms of the dynamics and statistics of a classical-field system. It proceeds by explaining how this framework emerges in realistic quantum systems, with examples that include liquid helium, high-temperature superconductors, ultra-cold atomic bosons and fermions, and nuclear matter. The book also offers several powerful modern approaches to the subject, such as functional and path integrals. Comprised of 15 chapters, this text: Establishes the fundamental macroscopic properties of superfluids and superconductors within the paradigm of the classical matter field Deals with a single-component neutral matter field Considers fundamentals and properties of superconductors Describes new physics of superfluidity and superconductivity that arises in multicomponent systems Presents the quantum-field perspective on the conditions under which classical-field description is relevant in bosonic and fermionic systems Introduces the path integral formalism Shows how Feynman path integrals can be efficiently simulated with the worm algorithm Explains why nonsuperfluid (insulating) ground states of regular and disordered bosons occur under appropriate conditions Explores superfluid solids (supersolids) Discusses the rich dynamics of vortices and various aspects of superfluid turbulence at T 0 Provides account of BCS theory for the weakly interacting Fermi gas Highlights and analyzes the most crucial developments that has led to the current understanding of superfluidity and superconductivity Reviews the variety of superfluid and superconducting systems available today in nature and the laboratory, as well as the states that experimental realization is currently actively pursuing

The physical and chemical properties and processes of clouds are of great interest from a variety of perspectives, such as acid deposition, oxidant chemistry, and radiative transfer in the atmosphere. The Kleiner Feldberg Cloud Experiment was conducted in October--November 1990 at the field observatory of Kleiner Feldberg near Frankfurt, Germany, in the Taunus Highlands. The experiment was planned and organized within the EUROTRAC sub- project GCE (Ground-Based Cloud Experiment). The general aim of this project is to experimentally investigate physical and chemical processes occurring in ground-based clouds, to provide the basic information needed to understand the incorporation and transformation of trace atmospheric constituents within the multiphase cloud system. This book reports the results of the Kleiner Feldberg Cloud Experiment, addressing the main scientific questions related to the properties of clouds and the processes taking place in the cloud multiphase system. How are the different atmospheric trace species partitioned between gas phase, interstitial aerosols, cloud droplets? What kind of physical and chemical processes cause changes in the phase partitioning of trace species within clouds? Which interactions can be found between the microphysical and dynamical processes in clouds and the chemical composition of cloud droplets? Is the chemical composition of cloud droplets size-dependent, as can be expected by the different scavenging processes? Which influence do chemical reactions have on cloud water chemical composition? Does the gas/liquid partitioning in cloud obey Henry's law? How important is the deposition of atmospheric trace substances due to cloud dropletinterception with the Earth's surface? Are the sampling techniques for aerosols and cloud droplets reliable with respect to their chemical composition? This book provides updated information on cloud research to scientists involved in other fields of atmospheric sciences and also useful reference material for graduate students enrolled in atmospheric chemistry programmes.

Biomaterials are advanced materials that garner interdisciplinary research. Wastewater pollution causes many adverse effects on human health and the environment. In order to rectify this, biomaterials and other nanomaterials have been utilized as photocatalysts against environmental waste. In this book, biomaterials are highlighted as a promising material for waste management, as biomaterials are cost-effective, eco-friendly and closer to nature.

"Fundamentals of Medicinal Chemistry is a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. Starting with a review of the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms, the text then covers the discovery and design of drugs, pharmacokinetics and drug metabolism. The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing of the final product.

The text assumes little in the way of prior biological knowledge and only a basic chemical knowledge. Relevant biology is included through biological topics, examples and in the Appendices. A concise introduction to the essentials of medicinal chemistry Assumes little prior knowledge of biology. Incorporates summary sections, examples, applications and problems, along with their solutions. Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.

Production from tropical agricultural systems will need to increase to satisfy the rising food demand of an increasing population coupled with changes in consumption patterns. At the same time, the agricultural sector is a significant source of greenhouse gases (GHG) in many developing countries, which can be attributed mainly to land-use change and methane emissions from rice and livestock. But how can we reconcile less GHG emissions from tropical agricultural systems while increasing productivity?

Due to the interactive nature of these issues, this book is compiled of articles on natural resource management, as well as the socio-economic aspects of GHG mitigation. The scope of mitigation options in tropical agriculture is discussed for three different activities: (a) agroforestry; (b) rice-based production systems; (c) pasture/animal husbandry.

Agronomic solutions alone will not be sufficient, as the institutional and economic frameworks within which farmers operate dictate whether a recommended agronomic management practice is acceptable. The prevention of deforestation, and the re-forestation of degraded land, could become key elements to national climate protection programs of some developing countries. Alternative management practices in rice-based and pasture systems may offer win-win options to reduce emissions and improve resource-use efficiencies.

This book is for undergraduate and diploma chemistry students who are about to begin their project work. Student projects are now an essential part of most undergraduate and diploma chemistry courses in the UK, and are an important component of the later years of chemistry degree courses in Australia, South Africa and New Zealand The book covers all aspects of project work, from choosing a suitable topic and supervisor to communicating research results effectively. There is advice on the best way to use libraries and on how to gather relevant references. Students are taught how to work safely and effectively, and to present their results in report, seminar or conference poster form. Additionally, the author offers guidance on engaging a keyboard operator, on how to prepare artwork and visual aids, and coaching tips on effective communication. The work is a distillation of the author's many years of experience of guiding students of all abilities to success in their project work This book should be of interest to second and third year undergraduates and diploma students in chemistry.

This book is tailored designed for both researchers as well as academics teaching or introducing Advanced Manufacturing course to their classrooms. It presents the current state of research in this field of research and major challenges identified so far, for the integration of additive manufacturing into chemical processes. Unique capability of transforming materials into functional devices with specific geometry using the emerging additive manufacturing technologies has stimulated significant interest in biology, engineering and materials science, to provide custom-made designs for tailored applications. However, the applications of this emerging technology in the field of chemical sciences and engineering have started very recently. Therefore, the major focus of this book is to introduce the basic principles of additive manufacturing practices as well as advent into conventional chemical processes and various unit operations. The potential advantage of introducing these additive manufacturing technologies has the potential to scale down large scale chemical processes into small scale, which offers several advantages including lower foot print, waste reduction and efficient heat integration as well as distributed chemical manufacturing.

The book provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. The book focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides. The book starts with an introductory overview of bioanalysis showcasing the integral role it plays in understanding the drug disposition (pharmacokinetics/pharmacodynamics and immunogenicity) and the progression of bioanalytical strategy as the drug progresses through discovery and development stages of the program, taking into consideration the continually evolving regulatory landscape. The book further diversifies into individual biopharmaceutical modalities - monoclonal antibodies, antibody-drug conjugates, bispecifics, Fc-fusion proteins, gene therapies, cell therapies, peptides and oligonucleotides. The individual chapters focus on modality-specific bioanalytical assay strategies, critical reagents, assay formats, analytical platforms, associated bioanalytical challenges and mitigation strategies, industry best practices, and the latest understanding of regulatory guidance as applicable to the fast-growing biopharmaceutical landscape.

This book provides an integrated account of the phenomenon of acidity set against the background of the acidic substances which are of major significance in the chemical industry and commerce.

This detailed volume provides state-of-the-art methodologies and reviews of important topics in the field of homology modeling. From homology modeling in the twilight zone and improving accuracy through sequence space analysis to approaches to construct multi-protein complex models, the book explores a wide variety of uses and applications of this valuable technique. Written for the highly successful Methods in Molecular Biology series, the chapters include introductions to their respective topics, lists of the necessary programs, webservers, and databases, step-by-step and readily reproducible protocols, as well as tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Homology Modeling: Methods and Protocols serves as an ideal guide to recent homology modeling procedures, assumptions made, and model quality assessment that will illuminate the black box of homology modeling for novice readers and broaden the knowledge of this methodology for professionals.

This brilliant CGP book covers all the maths skills needed in AS and A-Level Chemistry (the use of maths is required for 20% of the marks in the final exams and assessments). It explains Calculations, Units, Handling Data, Graph Skills and Geometry, with clear study notes and step-by-step examples in the context of Chemistry. And to make sure you've really got to grips with it all, there are practice questions for each topic - with answers included at the back of the book.

Originally, scientists believed that molecules were three-dimensional; however, studies have proven that geometric dimensions are continuous. Therefore, molecules are able to have higher dimensions which influences how they interact with other molecules leading to advances in various fields including nanomedicine, nanotoxicology and quantum biology. Chemical Compound Structures and the Higher Dimension of Molecules: Emerging Research and Opportunities is a pivotal reference work studying the relationship between chemical compounds and dimensional space. Featuring comprehensive coverage across a range of related topics, such as convex polytypes, Euler-Poincare equations, intermolecular interactions, and the Schrodiner equation, this book is an ideal reference source for academicians, researchers, and advance-level students seeking innovative research on molecule dimensions and interactions.

Nanorobotics and Nanodiagnostics in Integrative Biology and Biomedicine "Nanorobotics and nanodiagnostics" can be defined as a new generation of biohybrid and nanorobotics that translate fundamental biological principles into engineering design rules, or integrative living components into synthetic structures to create biorobots and nanodiagnotics that perform like natural systems. Nanorobots or nanobots are structured of a nanoscale made of individual assemblies. They can be termed as intelligent systems manufactured with self-assembly strategies by chemical, physical and biological approaches. The nanorobot can determine the structure and enhance the adaptability to the environment in interdisciplinary tasks. "Nanorobotics and nanodiagnostics" is a new generation of biohybrid that translates fundamental biological principles into engineering design rules to create biorobots that perform like natural systems. These biorobotics and diagnostics can now perform various missions to be accomplished certain tasks in the research areas such as integrative biology and biomedicine. "Nanorobotics and Nanodiagnostics in Integrative Biology and Biomedicine" sheds light on a comprehensive overview of the multidisciplinary areas that explore nanotherapeutics and nanorobotic manipulation in biology and medicine. It provides up-to-date knowledge of the promising fields of integrative biology and biomedicine for nano-assisted biorobotics and diagnostics to detect and treat diseases that will enable new scientific discoveries.

The classic book that presents a unified approach to crystallography and the defects found within crystals, revised and updated This new edition of Crystallography and Crystal Defects explains the modern concepts of crystallography in a clear, succinct manner and shows how to apply these concepts in the analyses of point, line and planar defects in crystalline materials. Fully revised and updated, this book now includes: Original source references to key crystallographic terms familiar to materials scientists Expanded discussion on the elasticity of cubic materials New content on texture that contains more detail on Euler angles, orientation distribution functions and an expanded discussion on examples of textures in engineering materials Additional content on dislocations in materials of symmetry lower than cubic An expanded discussion of twinning which includes the description and classification of growth twins The inclusion and explanation of results from atomistic modelling of twin boundaries Problem sets with new questions, detailed worked solutions, supplementary lecture material and online computer programs for crystallographic calculations. Written by authors with extensive lecturing experience at undergraduate level, Crystallography and Crystal Defects, Third Edition continues to take its place as the core text on the topic and provides the essential resource for students and researchers in metallurgy, materials science, physics, chemistry, electrical, civil and mechanical engineering.

Food authentication is an issue that has become increasingly important over recent years due in part to the legislative trend away from compositional legislation to label declaration. In the US and Europe working groups have been established to bring scientists, industry and the government together to exchange information about food authenticity. This book surveys the range of analytical methods applied to investigate and confirm authenticity or adulteration. Food manufacturers need to ensure that their products meet the demands of legislation in the countries where they are sold, where as governments need to ensure that tested and valid methods are available to meet the needs of industry and to protect the public from misleading or fradulent labelling. The book assesses the applicability of various methods according to the needs of these different groups. The text should be of interest to analytical chemists, quality assurance personnel, and enforcement officers in local and national governments.

Cycloadditions are a very important class of reactions, which can be 1 used to obtain compounds of various ring sizes * Although these ,2 react? been largf: nvnntigated expnnivnntntit consi:fn ee f, :~oversy still fgeir mechanism, A reaction gene' ves the formaci new (J bonds between the reactants at the expense of n bonds. For such processes it is possible to postulate three different mechanisms: i) a synchron.ous concerted approach involving a cyclic transition state (TS) new bonds formed extent: ii)a neynchronous co:,:':" m:"chanism in whict fWO disticc to changes in e:f,me occurring the reactants and the single TS and the others mainly between the TS and products. iii) a two-step process, which occurs in two kinetically distinct steps via a ghnntical intermedintn Renect! gene computed the petential enerse or the ies of prototype tion reaction:f 4a i) the [2+2] cycloadditions H2C=CH2 + H C=CH , H C=O + H C=O,':b 2 2 2 2 H2 = 2 + O=O:4c C CH ii) the 1,3 dipolar cycloaddition HCNO + HC=CH, HCNO + H2C=CH2, H2CNHO 4d + H2C=CHd' 4e iii) cgdoaddition H C=CH * 2 2 have been potential enenpd th (STO-3G)5 ab-ini techniques f:ntcnged (4-31G)6 basis sets. All critical points have been fully optimized 7 using MC-SCF gradient techniques and characterized by diagonalizing 35 the related Hessian matrices computed using finite differences.

This is a completely revised and updated edition of the comprehensive and widely used survey of cereal technology. The first section describes the botany, classification, structure, composition, nutritional importantance and uses of wheat, corn, oats, rye, sorghum, rice and barley, as well as six other grains. The book also details the latest methods of producing, cleaning, and storing these grains. The second section of the book offers current information on the technological and engineering principles of feed milling, flour milling, baking, malting, brewing, manufacturing breakfast cereals, snack food production, wet milling (starch and oil production from grains), rice processing, and other upgrading procedures applied to cereal grains. This section also explains the value and utilization of by-products and examines many rarely discussed processing methods. In addition, the book provides reviews of current knowledge on the dietary importance of cereal proteins, lipids, fibre, vitamins, minerals, and anti-nutrient factors, as well as the effects of processing methods on these materials. This book should be of interest to those involved in agriculture, meat production and food science/technology.

A definitive, single source of information on PBPK modeling
Physiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling purposes so users can quickly access information, this is the first comprehensive reference of its kind.
This book presents an overview of the underlying principles of PBPK model development. Then it provides a compendium of PBPK modeling information, including historical development, specific modeling challenges, and current practices for:
* Halogenated Alkanes
* Halogenated Alkenes
* Alkene and Aromatic Compounds
* Reactive Vapors in the Nasal Cavity
* Alkanes, Oxyhydrocarbons, and Related Compounds
* Pesticides and Persistent Organic Pollutants
* Dioxin and Related Compounds
* Metals and Inorganic Compounds
* Drugs
* Antineoplastic Agents
* Perinatal Transfer
* Mixtures
* Dermal Exposure Models
In addition to pinpointing specific information, readers can explore diverse modeling techniques and applications. An authoritative reference for toxicologists, ecotoxicologists, risk assessors, regulators, pharmacologists, pharmacists, and graduate students in pharmacokinetics and toxicology, Physiologically-Based Pharmacokinetic Modeling compiles information from leaders in the field and discusses future directions for PBPK modeling.