Cardiology Science and Technology comprehensively deals with the science and biomedical engineering formulations of cardiology. As a textbook, it addresses the teaching, research, and clinical aspects of cardiovascular medical engineering and computational cardiology. The books consists of two sections. The first section deals with left ventricular (LV) wall stress, cardiac contractility, ventricular remodeling, active wall stress and systolic pressure generation, and vector cardiogram characteristics, with applications in cardiology. The second section covers ECG signal analysis for arrhythmias detection, LV pumping (intra-LV, aortic and coronary flow) characteristics, and coronary bypass surgery design, with applications in cardiology and cardiac surgery. This book is like an exciting train ride through the heart and into blood flows within its chamber, the coronary tree, the aorta, and finally into coronary flow and bypass grafting. The train starts from the heart's central station and journeys through exciting places of heart wall stresses, cardiac contractility measures to characterize heart failure, and active stress generation to develop systolic heart pressure. We learn about cardiomyopathic heart remodeling and its surgical ventricular restoration, theory of ECG and vector cardiogram with medical applications, and heart rate variability signal processing to detect cardiac arrhythmias. In the heart chamber, we witness the amazing intricate intra-ventricular flow patterns. Then, we study pressure pulse wave propagation into the aorta, determination of pulse wave velocity and arterial elasticity as a measure of arteriosclerosis. We climb into the mountainous coronary terrain and look at the fascinating scenery of coronary flows and myocardial perfusion that governs cardiac contractility. Finally, we arrive at coronary bypass grafting and witness the new sequential anastomosis design for enhanced patency.

Polymers have emerged as one of the most innovative classes of materials in modern materials science, leading to new applications in medicine and pharmacy. This book offers a convincing and understandable approach to polymer biomaterial devices being used in various areas related to biomedical and pharmaceutical fields. The polymer materials finding application as biomaterials are discussed and described in detail pertaining to the areas of artificial implants, orthopedics, ocular devices, dental implants, drug delivery systems, burns and wounds.

The application of Biotechnology dates back to the early era of civilization, when people first started to cultivate food crops. While the early applications are certainly still relevant, modern biotechnology is primarily associated with molecular biology, cloning and genetic engineering not only to increase the yield and to improve the quality of the crop but also its potential impact has touched upon virtually all domains of human interactions. Within the last 50 years, several key scientific discoveries revolutionized the biological sciences that facilitated the rapid growth of the biotechnology industry. 'Biotechnology and Biological Sciences III' contains the contributions presented at the 3rd International Conference on Biotechnology and Biological Sciences (BIOSPECTRUM 2019, Kolkata, India, 8-10 August 2019). The papers discuss various aspects of Biotechnology such as: microbial biotechnology, bioinformatics and drug designing, innovations in pharmaceutical industries and food processing industries, bioremediation, nano-biotechnology, and molecular-genetics, and will be of interest to academics and professionals involved or interested in these subject areas.

Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools. Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment. Addressing important clinical questions in cancer research will benefit from expanding computational biology. The advent of genomic and proteomic technologies has ushered forth the era of genuine medicine. The promise of these advances is true personalized medicine where treatment strategies can be individually tailored and advance to initiating intervention before visible symptoms appear.

This book covers emerging trends in signal processing research and biomedical engineering, exploring the ways in which signal processing plays a vital role in applications ranging from medical electronics to data mining of electronic medical records. Topics covered include statistical modeling of electroencephalograph data for predicting or detecting seizure, stroke, or Parkinson's; machine learning methods and their application to biomedical problems, which is often poorly understood, even within the scientific community; signal analysis; medical imaging; and machine learning, data mining, and classification. The book features tutorials and examples of successful applications that will appeal to a wide range of professionals and researchers interested in applications of signal processing, medicine, and biology.

This volume explores developments in techniques in diagnostics, DNA sequencing, bioanalysis of immunoassays, and single-molecule detection. It promotes the measurement, identification, monitoring, analysis, and application of near-infrared spectroscopy (NIR) to medical and pharmaceutical advances. The text also considers noninvasive methods of NIR for successful, cost-effective, and prompt diagnoses of diseases.

Summarizing state-of-the-art developments in long-term mechanical ventilation use, this comprehensive treatise reviews the applications, complications, and care of breathing disorders affecting the growing population of ventilation-assisted individuals-including neuromuscular and chronic obstructive pulmonary diseases (COPD) and chest wall deformities.
Qualitatively considers reimbursement options for management outside of acute care settings
Covering both noninvasive ventilation (NIV) and invasive ventilation techniques and procedures, Long-Term Mechanical Ventilation
provides an epidemiology of long-term mechanical ventilation with a review of recent trends
examines the pathophysiological mechanisms contributing to chronic respiratory failure, including the pathogenesis and treatment of restrictive thoracic and central hypoventilatory disorders
investigates the controversy over conflicting results for NIV management of patients with chronic respiratory failure due to severe stable COPD
details critical care for children with severe ventilatory defects such as congenital neuromuscular diseases, cystic fibrosis, and bronchopulmonary dysplasia
chronicles new insights into the role of the upper airway and glottis in determining the effectiveness of NIV
considers weaning dependent patients off ventilation and methods of care for different sites using the least complicated and most economical means
explores tools for measuring the impact and outcomes of long-term mechanical ventilation and determining patients' quality of life
and more
Containing over 1400 literature references, tables, drawings, and photographs, Long-Term Mechanical Ventilation is a necessary reference for pulmonary and thoracic specialists, chest physicians, anesthesiologists, physiologists, physiatrists and rehabilitation physicians, respiratory therapists, intensive care specialists, and medical school and graduate school students in these disciplines.

There is a wealth of health information on the internet. Today's students of health studies and all health care professionals must be able to use this valuable resource and extract from it what is most relevant and useful. In order for them to do this purposefully and skilfully, they need to have a thorough understanding of how the system works and have the ability to navigate their way around it with ease.
The Essential Guide to the Internet for Health Professionals is a superb photocopiable resource for lecturers. It shows students:
*how to get online
*how to navigate the worldwide web
*how to find health information on the internet
*how to communicate with other health professionals
*how to access free health and medical resources
*how to publish on the web
*how to use online help with health studies assignments
*how to search for jobs
Each chapter contains easy-to-follow activities and photocopiable worksheets.

eBook available with sample pages: EB:0203465644

Through the use of new technologies, researchers, and practitioners in health education and health communication can now provide health information and behavior change strategies that are customized based on the unique needs, interests, and concerns of different individuals. These tailored health messages can be highly effective in assisting individuals in understanding and responding to health concerns.
In this volume, Matthew Kreuter, David Farrell, and their colleagues define the process of tailoring and describe its uses in health communication programs. They present a theoretical and public health rationale for tailoring and support their position with empirical evidence. They also lay out the steps involved in creating and delivering tailored health communication programs, which can then be applied in practice. Practitioners, researchers, and students in health communication, health psychology, public health, and related areas will find this book to be a vital and invaluable resource for improving communication about health issues.

This is a practical book for health and IT professionals who need to ensure that patient safety is prioritized in the design and implementation of clinical information technology. Healthcare professionals are increasingly reliant on information technology to deliver care and inform their clinical decision making. Health IT provides enormous benefits in efficiency, communication and decision making. However a number of high-profile UK and US studies have concluded that when Health IT is poorly designed or sub-optimally implemented then patient safety can be compromised. Manufacturers and healthcare organizations are increasingly required to demonstrate that their Health IT solutions are proactively assured. Surprisingly the majority of systems are not subject to regulation so there is little in the way of practical guidance as to how risk management can be achieved. The book fills that gap. The author, a doctor and IT professional, harnesses his two decades of experience to characterize the hazards that health technology can introduce. Risk can never be eliminated but by drawing on lessons from other safety-critical industries the book systematically sets out how clinical risk can be strategically controlled. The book proposes the employment of a Safety Case to articulate and justify residual risk so that not only is risk proactively managed but it is seen to be managed. These simple techniques drive product quality and allow a technology's benefits to be realized without compromising patient safety.

Thoroughly authoritative with contributions from experts in the field, this completely updated and expanded Second Edition details state-of-the-art developments in industry practices and standards relating to medical device packaging in a readily accessible format. Helps beginning and seasoned practitioners comply with recent and pending FDA Quality Systems Good Manufacturing Practices, European Medical Device Directives, ISO 14000, and other international standards and requirements The Medical Device Packaging Handbook, Second Edition offers entirely new as well as revised chapters on packaging materials sterilization techniques, such as vapor phase processes, shelf-life testing, and expriation dating package validation methods and integrity testing bar coding technology environmentally sound packaging and disposal procedures storage autoclave case systems international standards and compliance customer needs regulatory aspects and more Elucidating discussions with an extensive glossary and index as well as many novel references, tables, drawings and photographs, this timely Second Edition furnishes instructional, practical information for packaging, validation, process, and materials engineers; packaging designers; microbiologists, toxicologists; pharmacologists; pharmacists; drug manufacturers, distributors, and suppliers; quality assurance and food and drug regulatory personnel; and graduate-level students in these disciplines.

This essential reference acquaints developers of medical devices with the basic concepts and major issues of medical quality assurance and regulatory documents, describes the requirements listed in these documents, and provides strategies for compliance with these requirements. Medical Device Quality Assurance and Regulatory Compliance summarizes regulation activities of the FDA, the European Economic Community, and the Global Harmonization Task Force shows how to choose a standard from the ISO 9000 and ISO 14000 series teaches how to prepare your company for auditing, how to choose a notified body, and how to survive the audit reviews standards dealing specifically with medical devices such as EN 46000, ISO 13485, and ISO 13488 discusses the requirements for product submittals prior to product introduction addresses current issues such as third party approvals and more Including numerous key references, tables, and drawings, Medical Device Quality Assurance and Regulatory Compliance is ideal for biomedical, quality assurance, reliability, software, product design, manufacturing, research and development, and industrial engineers; project managers; biomedical technicians; medical device purchasing personnel; and upper-level undergraduate and graduate students in these disciplines.

Minimally invasive medicine has the goal of providing health care with minimal trauma. When minimally invasive surgery is utilized, it reduces the length of hospital stays, lowers costs, lowers pain, and reduces blood loss. Other minimally invasive techniques minimize radiation exposure, tissue damage, and drug side effects. Collecting contributions from workers in various fields within the sphere of minimally invasive medical technology, this book provides essential information for those involved with researching, designing, and using minimally invasive devices and systems. It emphasizes the technology required to accomplish minimally invasive medicine. The book will be of interest to biomedical engineers, medical physicists, and health care providers who want to know the technical workings of their devices and instruments.

This new text provides a practical guide to hydrophilic polymer coatings technology for applications in a wide range of medical materials and devices. It concisely provides both the scientific basics of this class of polymers and the up-to-date information needed for product development and evaluation, processing, manufacturing, and regulatory compliance. More than fifty schematics illustrate materials, processes, and equipment. The entire presentation is oriented to the practical needs of personnel involved in product development and evaluation, process engineering, and manufacturing management.

In Sight is a memoir about how a love of science and discovery drove Julia Levy, a celebrated scholar and biotech CEO, to work her way through gender bias in order to achieve academic and professional recognition. Her story traces the unconventional invention of a breakthrough drug treatment from its development from laboratory research to its application as a medical treatment for vision loss. Told from a female perspective, In Sight is a unique and personal story covering Levy's early years as a refugee, her university training in the UK, and her appointment as professor at the University of British Columbia. Years spent as an academic led the author to unexpected exposure to the biotechnology industry and a chance meeting with colleagues that led to the formation of a lucrative biotechnology company, known today as QLT Inc. The bulk of the book covers the years spent building the company, and Levy's surprising transition from chief scientific officer to CEO. In Sight is an honest description of the trials of drug development, the tensions inherent in the commercialization of health innovations, and the truly remarkable hurdles faced by women in the scientific community.

This new book will enable family practitioners, obstetricians and pediatricians to answer the concerns of the families in their care. It is the first book to make information on this important topic so easily accessible to clinicians. The book is firmly rooted in clinical practice and based on many years of experience, much of it involving the development and implementation of new techniques for examining the fetus in utero. The techniques now available are assessed and better ways to identify pregnancies which are eligible to their application are proposed. The authors describe both the sampling and laboratory techniques available. Other sections cover both predictable and unpredictable pregnancy risks from genetic diseases to abnormal ultrasound, including the possibilities for laboratory evaluation, and the risks and limitations. Throughout the book, the special status of the fetus as a patient is emphasized and the concerns and questions of families are considered, making this the first fully comprehensive and authoritative volume on fetal medicine.

In Reproduction, Technology, and Rights, philosophers and ethicists debate the central moral issues and problems raised by today's revolution in reproductive technology. Leading issues discussed include the ethics of paternal obligations to children, the place of in vitro fertilization in the allocation of health care resources, and the ethical implications of such new technologies as blastomere separation and cloning. Also considered are how parents and society should respond to knowledge gained from prenatal testing and whether or not the right to abort should relieve men of the duty to support unwanted children.
Reproduction, Technology, and Rights illuminates the moral and ethical choices that our society faces because of advances in reproductive technology and helps to make those decisions better informed.

This book provides a comprehensive overview of deep learning (DL) in medical and healthcare applications, including the fundamentals and current advances in medical image analysis, state-of-the-art DL methods for medical image analysis and real-world, deep learning-based clinical computer-aided diagnosis systems. Deep learning (DL) is one of the key techniques of artificial intelligence (AI) and today plays an important role in numerous academic and industrial areas. DL involves using a neural network with many layers (deep structure) between input and output, and its main advantage of is that it can automatically learn data-driven, highly representative and hierarchical features and perform feature extraction and classification on one network. DL can be used to model or simulate an intelligent system or process using annotated training data. Recently, DL has become widely used in medical applications, such as anatomic modelling, tumour detection, disease classification, computer-aided diagnosis and surgical planning. This book is intended for computer science and engineering students and researchers, medical professionals and anyone interested using DL techniques.

Contents:
Electromyography in ergonomics; physiological basis and concepts of electromyography; noise and artefacts; EMG interpretation; muscle energetics and electromyography; EMG alterations at sustained contractions with special emphasis on application in ergonomics; electromyography of upper extremity muscles and ergonomic applications; EMG of neck and shoulder muscles - the relationship between muscle activity and muscle pain in occupational settings; surface electromyography assessment of lower back pain; application of EMG in ergonomics - a clinical perspective.

From the Author's Preface
There is a growing demand for ultrapure organic compounds such as fine chemicals, pharmaceuticals, and basic materials for use in the polymer industry. . . . In quite a number of cases, it is difficult or impossible to manufacture ultrapure organics efficiently using conventional separation techniques such as distillation. Moreover, conventional techniques usually require large amounts of energy.
To improve the purification efficiency of organics, special techniques based on crystallization from the melt have been developed. Melt crystallization meets industry's need for a highly selective separation process for organic compounds which operates at low enough temperatures to prevent thermal degradation. Melt crystallization processes have the added advantage that they are energy-efficient and ecologically sound.
Melt crystallization techniques appear to be particularly promising for upgrading organic materials and are one of the few routes that appear to be feasible for purifying starter materials for high-tech polymers. The aim of this book is to provide basic information on melt crystallization technology. . . . This monograph consists of three parts: 1. basic principles, 2. process options, and 3. technical equipment and applicability.
This new book is the first unified guide and reference to an important chemical process technology. It is comprehensive and organized for easy reference. More than 150 diagrammatic representations, flow charts and photographs illustrate equipment and processes. More than 40 tables provide useful reference data.
The Author
Dr. Arkenbout studied chemistry at the University of Utrecht, and joined TNO, the Netherlands Organization for Applied Scientific Research. He has specialized in research on new separation processes and has had thirty of his articles on this subject published. He recently retired from the position of manager of physical separation research, but has remained active in this field through affiliations with the Laboratory of Solid State Chemistry at the University of Nijmegen, the Laboratory for Process Equipment, Delft University of Technology, and TNO.

The discipline of rehabilitation engineering draws on a wide range of specialist knowledge, from the biomedical sciences to materials technology. Rehabilitation Engineering Applied to Mobility and Manipulation provides broad background and motivational material to ease readers' introduction to the subject. The book begins with a wide-ranging yet concise introduction to the legislative, technological, testing, and design basis of rehabilitation engineering, followed by the fundamentals of design and materials and a full account of the biomechanics of rehabilitation. Major sections of the book are devoted to various aspects of mobility, including detailed discussion of wheelchair design. Valuable additional material deals with seating, prosthetic devices, robotics, and the often-neglected subject of recreational devices and vehicles. More than a thousand references to the research and review literature put readers in touch with the leading edge of a rapidly growing field.

Electronic communications are already revolutionizing the delivery of health care in homes and communities. The medium will have increasing impact on the delivery of health care in response to the pressure to use limited resources cost-effectively. To date much of telematics in health care has focused on hospital-based bio-medicine. In this book a case is made for reorientation of telematic activity towards the use of "low tech" (social) technologies supported by "Health for All" philosophies. This book uses several case studies of pilot schemes to illustrate how the models can be applied in a variety of settings. Experience of telematics in America, Canada, Germany, Italy, The Netherlands, Portugal and Wales is shared for an international readership of innovators in health care management.

About this book— In recent years, a number of different spectroscopic techniques have been applied to the study of a wide range of biomedical topics. Biomedical investigations in fields as diverse as eye lens research, the study of cardiovascular and inflammatory diseases, and the study of oxidative stress in disease can now be carried out by spectroscopic means. The nine chapters in Biomedical Applications of Spectroscopy present an authoritative overview of the current status of the field, with each chapter written by acknowledged experts. A wide range of techniques is considered, including optical microspectroscopy, Raman spectroscopy, FTIR spectroscopy, NMR and EPR spectroscopy and mass spectrometry. This highly topical volume will stimulate interest in this expanding field, and point the way towards future directions in research. The major objectives of this established series are to integrate theory and practice and to bring together different branches of both academic and industrial research through the presentation of critical review articles in fundamental and applied spectroscopy. The policy of the editors is to commission authoritative reviews by acknowledged leaders in the various fields of spectroscopy. Thus each volume presents a carefully composed picture of the ‘state of the art’ for a particular area. For each volume the subject matter is presented in a manner which is Comprehensible to the non-expert, for whom the series will continue to provide a valuable introduction, and a timely overview of topics in spectroscopy which are of current interest and importance. At the same time the involved expert will find much to engage his or her attention. The series is of interest to research scientists and technologists, to teachers and both graduate and undergraduate students.