Rapid progress in health research has led to generation of new knowledge and innovative practices in management of illness. This has resulted in a significant challenge for health professionals: if today we discovered a new therapy through research, when will this discovery be regularly prescribed or utilized to treat all patients suffering from this condition? Knowledge translation is the non-linear and often complicated process of translating knowledge into routine health practices. Technology enabled knowledge translation (TEKT) is the use of information and communication technologies (ICT) to accelerate knowledge translation. With the ubiquity of the internet, the proliferation of different approaches in communication and social networking, and the continuously improving technologies from netbooks to smartphones, there are rich opportunities for TEKT in health education, service delivery, and research.

Healthcare Information Management Systems, 4th edition, is a comprehensive volume addressing the technical, organizational and management issues confronted by healthcare professionals in the selection, implementation and management of healthcare information systems. With contributions from experts in the field, this book focuses on topics such as strategic planning, turning a plan into reality, implementation, patient-centered technologies, privacy, the new culture of patient safety and the future of technologies in progress. With the addition of many new chapters, the 4th Edition is also richly peppered with case studies of implementation. The case studies are evidence that information technology can be implemented efficiently to yield results, yet they do not overlook pitfalls, hurdles, and other challenges that are encountered. Designed for use by physicians, nurses, nursing and medical directors, department heads, CEOs, CFOs, CIOs, COOs, and healthcare informaticians, the book aims to be a indispensible reference.

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included.

New technologies in 3D printing offer innovative capabilities in surgery, from planning complex operations through to educational purposes and providing alternatives to traditional training with more cost-effective outcomes. This hot topic title synthesizes the most up-to-date information on 3D printing and its application into surgical specialties including, hebatobilliary and pancreatic surgery, vascular surgery, orthopedic surgery, obstetrics and gynecology, cardiovascular and thoracic surgery, and more. Discusses challenges and opportunities of 3D printing across surgical sub-specialties. Covers 3D printing and its application in major surgical specialties, as well as dentistry, transplantation, global surgery, and diagnostic and interventional radiology. Consolidates today's available information on this burgeoning topic into a single convenient resource.

New computerized approaches to various problems have become critically important in healthcare. Computer assisted diagnosis has been extended towards a support of the clinical treatment. Mathematical information analysis, computer applications together with medical equipment and instruments have become standard tools underpinning the current rapid progress with developing Computational Intelligence. We are witnessing a radical change as technologies have been integrated into systems that address the core of medicine, including patient care in ambulatory and in-patient setting, disease prevention, health promotion, rehabilitation and home care. Computer aided diagnosis and treatment systems increase the objectivity of the analysis and speed up the response to pathological changes.

This book presents a variety of state-of-the-art information technology and its applications to the networked environment to allow robust computerized approaches to be introduced throughout the healthcare enterprise. Patient's safety and shortening of the rehabilitation time requires a more rapid development of minimally invasive surgery supported by image navigation techniques. Home care, remote rehabilitation assistance, safety of the elderly requires new areas to be explored in telemedicine and telegeriatrics.

This book is a great reference tool for scientists who deal with problems of designing and implementing processing tools employed in systems that assist clinicians in patient diagnosis and treatment."

New computerized approaches to various problems have become critically important in healthcare. Computer assisted diagnosis has been extended towards a support of the clinical treatment. Mathematical information analysis, computer applications have become standard tools underpinning the current rapid progress with developing Computational Intelligence. A computerized support in the analysis of patient information and implementation of a computer aided diagnosis and treatment systems, increases the objectivity of the analysis and speeds up the response to pathological changes.

This book presents a variety of state-of-the-art information technology and its applications to the networked environment to allow robust computerized approaches to be introduced throughout the healthcare enterprise. Image analysis and its application is the traditional part that deals with the problem of data processing, recognition and classification. Bioinformatics has become a dynamically developed field of computer assisted biological data analysis.

This book is a great reference tool for scientists who deal with problems of designing and implementing processing tools employed in systems that assist the radiologists and biologists in patient data analysis.

Computer technology has developed remarkably in the field of neurosurgery during the past 10 to 20 years. Great achievements have been made recently in neuroimaging techniques and computer technology for neuronavigation, from frameless, armless systems to robotic microscopes. Contained in the present volume are all the papers presented at the International Symposium on Computer-Assisted Neurosurgery and selected papers presented at the 6th Annual Meeting of the Japanese Society of Computers in Neurosurgery, which were held in Kobe, Japan, on January 24-26, 1997. This volume is a comprehensive description and review of current technical ad vancements in computer-assisted neurosurgery, with a special focus on advanced intraoperative neuroimaging, various neuronavigation system, robotic microscopes, and strategies for preoperative and intraoperative surgical planning using high-power workstations with three-dimensional software. We express our thanks to the contributors for their participation and cooperation, and to Springer-Verlag for personal and technical assistance in publishing this work. We sincerely hope that this volume will contribute to improving neurosurgical technology and outcomes.

In nowadays aging society, many people require mobility assistance. Sometimes, assistive devices need a certain degree of autonomy when users' disabilities difficult manual control. However, clinicians report that excessive assistance may lead to loss of residual skills and frustration. Shared control focuses on deciding when users need help and providing it. Collaborative control aims at giving just the right amount of help in a transparent, seamless way. This book presents the collaborative control paradigm. User performance may be indicative of physical/cognitive condition, so it is used to decide how much help is needed. Besides, collaborative control integrates machine and user commands so that people contribute to self-motion at all times. Collaborative control was extensively tested for 3 years using a robotized wheelchair at a rehabilitation hospital in Rome with volunteer inpatients presenting different disabilities, ranging from mild to severe. We also present a taxonomy of common metrics for wheelchair navigation and tests are evaluated accordingly. Obtained results are coherent both from a quantitative and qualitative point of view.

Financial identity theft is well understood with clear underlying motives. Medical identity theft is new and presents a growing problem. The solutions to both problems however, are less clear.

The Economics of Financial and Medical Identity Theft discusses how the digital networked environment is critically different from the world of paper, eyeballs and pens. Many of the effective identity protections are embedded behind the eyeballs, where the presumably passive observer is actually a fairly keen student of human behavior. The emergence of medical identity theft and the implications of medical data privacy are described in the second section of this book.

The Economics of Financial and Medical Identity Theft also presents an overview of the current technology for identity management. The book closes with a series of vignettes in the last chapter, looking at the risks we may see in the future and how these risks can be mitigated or avoided.

The Cell-Surface Interaction, by J. S. Hayes, E. M. Czekanska and R. G. Richards. Studying Cell-Surface Interactions In Vitro: A Survey of Experimental Approaches and Techniques, by Stefanie Michaelis, Rudolf Robelek and Joachim Wegener. Harnessing Cell-Biomaterial Interactions for Osteochondral Tissue Regeneration, by Kyobum Kim, Diana M. Yoon, Antonios G. Mikos and F. Kurtis Kasper. Interaction of Cells with Decellularized Biological Materials, by Mathias Wilhelmi, Bettina Giere and Michael Harder. Evaluation of Biocompatibility Using In Vitro Methods: Interpretation and Limitations, by Arie Bruinink and Reto Luginbuehl. Artificial Scaffolds and Mesenchymal Stem Cells for Hard Tissues, by Margit Schulze and Edda Tobiasch. Bioactive Glass-Based Scaffolds for Bone Tissue Engineering, by Julia Will, Lutz-Christian Gerhardt and Aldo R. Boccaccini. Microenvironment Design for Stem Cell Fate Determination, by Tali Re em and Smadar Cohen. Stem Cell Differentiation Depending on Different Surfaces, by Sonja Kress, Anne Neumann, Birgit Weyand and Cornelia Kasper. Designing the Biocompatibility of Biohybrids, by Frank Witte, Ivonne Bartsch and Elmar Willbold. Interaction of Cartilage and Ceramic Matrix, by K. Wiegandt, C. Goepfert, R. Portner and R. Janssen. Bioresorption and Degradation of Biomaterials, by Debarun Das, Ziyang Zhang, Thomas Winkler, Meenakshi Mour, Christina I. Gunter, Michael M. Morlock, Hans-Gunther Machens and Arndt F. Schilling."

Biomarker discovery is an important area of biomedical research that may lead to significant breakthroughs in disease analysis and targeted therapy. Biomarkers are biological entities whose alterations are measurable and are characteristic of a particular biological condition. Discovering, managing, and interpreting knowledge of new biomarkers are challenging and attractive problems in the emerging field of biomedical informatics.

This volumeis a collection of state-of-the-artresearch into the application of data mining to the discovery and analysis of new biomarkers. Presenting new results, models and algorithms, the included contributions focus on biomarker data integration, information retrieval methods, and statistical machine learning techniques.

This volume is intended for students, and researchers in bioinformatics, proteomics, and genomics, as wellengineers and applied scientistsinterested in the interdisciplinary application of data mining techniques."

A Focus on 3D Printing for Healthcare Applications is an indispensable collection of articles for anyone interested in additive manufacturing and prosthetics. It includes insights and examples into 3D printing for:- Biomedical prototypes- Tissue engineering- Bone scaffold manufacturing- Dental applications 3D printing has huge potential to deliver tailored healthcare solutions. Find out some of the reasons why by reading this collection.

How do firms jointly develop open information infrastructures? To answer this question, this book draws on the results of a longitudinal research project covering the development of the pharmaceutical distribution industry in China from 2004 to 2012, focusing on the emergence and subsequent evolution of industry-wide information infrastructures. How do firms delimit areas of proprietary innovation in open innovation projects? How do firms coordinate, initiate, negotiate and implement the development of innovative infrastructures? How do processes and practices within firms enable and constrain such collective efforts? - This book provides answers to these questions and draws conclusions regarding the challenges and new capabilities that firms will need in a world in which participation in the building of open information infrastructures becomes a necessary task for commercial organizations.

This book informs readers of the needs and rationale for the integration of medical and dental care and information with an international perspective as to how and where medical and dental care separated into specific domains. It provide high level guidance on issues involved with care and data integration and how to achieve an integrated model of health care supported by integrated HIT. A patient typically expects that a visit to a dentist can usually be resolved immediately. This expectation places a premium on instant, accurate, thorough, and current information. The state-of-the-art of fully integrated (dental-medical) electronic health record (EHR) is covered and this is contrasted with the current state of dental-medical software. While dentists in the US Veterans Health Administration (VHA), the US Indian Health Service (IHS), or the US military, for example, have access to fully integrated health records, most US clinicians still gather information from separate sources via fax or phone calls. The authors provide an in-depth discussion of the role of informatics and information science in the articulation of medical and dental practices and clinical data with the focus on applied clinical informatics to improve quality of care, practice efficiency, coordination and continuity of care, communication between physicians and dentists and to provide a more comprehensive care for the patients. Lastly, the book examines advances in medical and dental research and how these may affect dentistry in the future. Most new advances in healthcare research are information-intensive.

This book lays out all the latest research in the area of multimedia data hiding. The book introduces multimedia signal processing and information hiding techniques. It includes multimedia representation, digital watermarking fundamentals and requirements of watermarking. It moves on to cover the recent advances in multimedia signal processing, before presenting information hiding techniques including steganography, secret sharing and watermarking. The final part of this book includes practical applications of intelligent multimedia signal processing and data hiding systems.

The development of effective methods for the prediction of ontological annotations is an important goal in computational biology, yet evaluating their performance is difficult due to problems caused by the structure of biomedical ontologies and incomplete annotations of genes. This work proposes an information-theoretic framework to evaluate the performance of computational protein function prediction. A Bayesian network is used, structured according to the underlying ontology, to model the prior probability of a protein's function. The concepts of misinformation and remaining uncertainty are then defined, that can be seen as analogs of precision and recall. Finally, semantic distance is proposed as a single statistic for ranking classification models. The approach is evaluated by analyzing three protein function predictors of gene ontology terms. The work addresses several weaknesses of current metrics, and provides valuable insights into the performance of protein function prediction tools.

This new edition surveys the full range of available structural equation modeling (SEM) methodologies. The book has been updated throughout to reflect the arrival of new software packages, which have made analysis much easier than in the past. Applications in a broad range of disciplines are discussed, particularly in the social sciences where many key concepts are not directly observable. This book presents SEM's development in its proper historical context-essential to understanding the application, strengths and weaknesses of each particular method. This book also surveys the emerging path and network approaches that complement and enhance SEM, and that are growing in importance. SEM's ability to accommodate unobservable theory constructs through latent variables is of significant importance to social scientists. Latent variable theory and application are comprehensively explained and methods are presented for extending their power, including guidelines for data preparation, sample size calculation and the special treatment of Likert scale data. Tables of software, methodologies and fit statistics provide a concise reference for any research program, helping assure that its conclusions are defensible and publishable.

This volume presents the proceedings of the International Conference on Health Informatics (ICHI). The conference was a new special topic conference initiative by the International Federation of Medical and Biological Engineering (IFMBE), held in Vilamoura, Portugal on 7-9 November, 2013. The main theme of the ICHI2013 was Integrating Information and Communication Technologies with Biomedicine for Global Health .

The proceedings offer a unique forum to examine enabling technologies of sensors, devices and systems that optimize the acquisition, transmission, processing, storage, retrieval of biomedical and health information as well as to report novel clinical applications of health information systems and the deployment of m-Health, e-Health, u-Health, p-Health and Telemedicine."

Chapter 1 offers an overview of the basic computer technology. Each succeeding chapter, describes the problems in medicine, followed by a review in chronological sequence of why and how computers were applied to try to meet these problems. Only the technical aspects of computer hardware, software, and communications are discussed as they are necessary to explain how the technology was applied. This approach generally led to defining the objectives for applications of medical informatics. At the end of each chapter, the author summarizes his personal views and interpretations of the chapter contents. Although the concurrent evolution of medical informatics in Canada, Europe, and Japan certainly influenced workers in the United States, the scope of this historical review is limited to the development of medical informatics within the United States. Furthermore, this review is limited to electronic digital computers; it excludes mechanical, analog, and hybrid computers.

Myocardial tissue engineering (MTE), a concept that intends to prolong patients life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered vehicle, which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE."

Swamy Laxminarayan was an outstanding researcher active in many diverse fields of science and technology. This liber amicorum in memory of Swamy Laxminarayan collects Medical and Biological Engineering and Informatics contributions to the Safety and Security of Individuals and Society. The authors are renowned scientists and the aim of their writing is to recall the enormous personal and scientific achievement of Swamy Laxminarayan.

In his treatment of activity measurement in the fields of medicine and psychology, Tryon gives us a book that clearly accomplishes the three purposes set out in its preface. The reader is definitely encouraged to wrestle with the concepts ofbehavior and activity in terms of "dynamic physical quantities." Moreover, the reader cannot help but become familiarized with the technology available for performing activity measurements. Motivation to use some of this technology is enhanced by the very extensive summary of other people's uses of it provided throughout the book. Readers may find the book provocative on a number of Ievels. It is concep tually provocative to those of us struggling with understanding basic issues in the assessment and measurement of behavior. It is practically provocative to those of us working with various forms of behavioral difference, especially in clinical popula tions. The book provokes because it is essentially an unfinished exploration, open ing us to numerous pathways that, when traveled, reveal still more paths to explore. In this sense the book should be heuristically useful both in the more traditional empirical sense, and in terms of its Stimulation of conceptual discussion."

This publication identifies and discusses important challenges affecting eHealth in the EU and North America in the three areas of law, ethics and governance. It makes meaningful contributions to the eHealth discourse by suggesting solutions and making recommendations for good practice and potential ways forward. Legal challenges discussed include issues related to electronic medical records, telemedicine, the Internet and pharmaceutical drugs, healthcare information systems and medical liability. Ethical challenges focus on telehealth and service delivery in the home, Web 2.0 and the Internet, patient perceptions and ethical frameworks. Governance challenges focus on IT governance in healthcare, governance and decision-making in acute care hospitals, and different models of eHealth governance. The publication provides useful support materials and readings for persons active in developing current understandings of the legal, ethical and governance challenges involved in the eHealth context.

This book is intended to serve as a reference for professionals in the medical device industry, particularly those seeking to learn from practical examples and case studies. Medical devices, like pharmaceuticals, are highly regulated, and the bar is raised constantly as patients and consumers expect the best-quality healthcare and safe and effective medical technologies. Obtaining marketing authorization is the first major hurdle that med techs need to overcome in their pursuit of commercial success. Most books on regulatory affairs present regulations in each jurisdiction separately: European Union, USA, Australia, Canada, and Japan. This book proposes practical solutions for a coherent, one-size-fits-all (or most) set of systems and processes in compliance with regulations in all key markets, throughout the life cycle of a medical device. It also contains key information about international harmonization efforts and recent regulatory trends in emerging markets; important terminology needed to understand the regulators' language; and examples, case studies, and practical recommendations that bridge the gap between regulatory theory and practice.

Medical Ventilator System Basics: A clinical guide is a user-friendly guide to the basic principles and the technical aspects of mechanical ventilation and modern complex ventilator systems. Designed to be used at the bed side by busy clinicians, this book demystifies the internal workings of ventilators so they can be used with confidence for day-to-day needs, for advanced ventilation, as well as for patients who are difficult to wean off the ventilator. Using clear language, the author guides the reader from pneumatic principles to the anatomy and physiology of respiration. Split into 16 easy to read chapters, this guide discusses the system components such as the ventilator, breathing circuit, and humidifier, and considers the major ventilator functions, including the control parameters and alarms. Including over 200 full-colour illustrations and practical troubleshooting information you can rely on, regardless of ventilator models or brands, this guide is an invaluable quick-reference resource for both experienced and inexperienced users.