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The discovery of uniform latex particles by polymer chemists of the Dow Chemical Company nearly 50 years ago opened up new exciting fields for scientists and physicians and established many new biomedical applications. Many in vitro diagnostic tests such as the latex agglutination tests, analytical cell and phagocytosis tests have since become rou- tine. They were all developed on the basis of small particles bound to biological active molecules and fluorescent and radioactive markers. Further developments are ongoing, with the focus now shifted to applications of polymer particles in the controlled and di- rected transport of drugs in living systems. Four important factors make microspheres interesting for in vivo applications: First, biocompatible polymer particles can be used to transport known amounts of drug and re- lease them in a controlled fashion. Second, particles can be made of materials which bio- degrade in living organisms without doing any harm. Third, particles with modified surfaces are able to avoid rapid capture by the reticuloendothelial system and therefore en- hance their blood circulation time. Fourth, combining particles with specific molecules may allow organ-directed targeting.
This book constitutes the refereed proceedings of the 6th
Conference on Artificial Intelligence in Medicine Europe, AIME'97,
held in Grenoble, France, in March 1997.
Since 1970, when the pulmonary artery catheter was introduced into clinical medicine, the technique of hemodynamic monitoring has expanded rapidly. The use of this essential procedure now encompasses the coronary care unit, the medical intensive care unit, the surgical intensive care unit, and the operating room; and an entire spectrum of physicians require this skill, including anesthesiologists, trauma surgeons, pulmonologists, nephrologists, critical care specialists, and cardiologists. Learning the proper performance of invasive techniques is essential for providing high quality patient care. This easy-to-use guide provides every important aspect of hemodynamic monitoring, and presents it in a straightforward and organized format. The book's table of contents is evidence of its exceptional organization and completeness: / Normal Physiology / Respiration / Cardiac Output / Arrhythmias / Acute Mitral Regurgitation and the V Wave / Tricuspid Regurgitation / Acute Left Ventricular Infarction / Right Ventricular Infarction / Acute Left Ventricular Ischemia / Chronic Congestive Heart Failure / Pericardial Tamponade / Pericardial Constriction & Restrictive Cardiomyopathy / Pulmonary Embolism / Trouble / Normal Values / Techniques Used in this Book.
Anwendungen von Laserstrahlung in der Medizin sollen unmittelbar der Gesundheit der Menschen zugute kommen. Die Erarbeitung von Laserverfahren setzt ein Zusammenwirken von Medizinern, Physikern und Technikern voraus. Seit 1973 fuhrt die Kongress-Messe LASER alle 2 Jahre die internationalen Experten in Munchen zusammen. Im Juni 1995 fanden der 12. Internationale Kongress Lasermedizin und die 10. Tagung der deutschen Gesellschaft fur Lasermedizin auf der LASER statt. Die Ergebnisse spiegeln eine aktuelle Standortbestimmung der Lasermedizin wider und vermitteln Perspektiven und Impulse fur zukunftige Entwicklungen. Der Inhalt der Vortrage wird daher im vorliegenden Band der Fachwelt zuganglich gemacht.
This volume discusses the current state of the nation's blood supply--including studies of blood availability, ways of enhancing blood collection and distribution, frozen red cell technology, logistical concerns in prepositioning frozen blood, extended liquid storage of red cells, and blood substitutes.
Addresses the most frequently asked questions physicians have about medical writing and oral presentations and offers practical solutions.
How did use of medical technology such as urinalyses, blood tests, and x-ray machines change patient care in early-twentieth-century American hospitals? To what extent was the use of new machines influenced by the ideas of scientific medicine and to what extent by the availability of newly structured facilities and trained personnel? Drawing on the medical treatment of more than 2,000 patients in Pennsylvania and New York hospitals, Howell traces the ways in which medical technology was used, not merely how it was talked about. He utilizes a wide range of sources--including medical texts, popular literature, and the visual arts--to explore how technology came to be such a central feature of medical care.
Howell also shows how changes in medical practice raised issues of gender, culture, and economics. Howell's analysis is especially timely in light of the ongoing debate over U.S. health care reform, a debate in which a central topic is the use and expense of medical technology. In a concluding chapter he applies the book's historical insights to medical practice today--asking why, for example, modern diagnostic tests have not been used to give doctors more time to spend with patients.
A guidebook addressing the three major financial centers in every phys ician's life: the medical practice, the pension plan and personal fina nces. Listing cases and examples, the author addresses these three int errelated financial centers in a two-phase process how to conduct prac tice management review and then how to use this process to establish a n ongoing system for successful total financial management.
This book introduces the field of Health Web Science and presents methods for information gathering from written social media data. It explores the availability and utility of the personal medical information shared on social media platforms and determines ways to apply this largely untapped information source to healthcare systems and public health monitoring. Introducing an innovative concept for integrating social media data with clinical data, it addresses the crucial aspect of combining experiential data from social media with clinical evidence, and explores how the variety of available social media content can be analyzed and implemented. The book tackles a range of topics including social media's role in healthcare, the gathering of shared information, and the integration of clinical and social media data. Application examples of social media for health monitoring, along with its usage in patient treatment are also provided. The book also considers the ethical and legal issues of gathering and utilizing social media data, along with the risks and challenges that must be considered when integrating social media data into healthcare choices. With an increased interest internationally in E-Health, Health 2.0, Medicine 2.0 and the recent birth of the discipline of Web Science, this book will be a valuable resource for researchers and practitioners investigating this emerging topic.
This volume is based on selected and updated papers from the symposium on "Basic Mechanisms of the EEG," which was held under the sponsor- ship of the German EEG Society in Hamburg on September 28-29, 1990. The intention of this symposium was to relate recent experimental, clini- cal, and neuropathological data on the basic mechanism that underlie the EEG. Although we know much about these mechanisms, there is still much more to be learned. The symposium was partly the continuation of an earlier symposium on "Origin of Cerebral Field Potentials" held in 1979 in Munster under the leadership of one of the present editors (E. -J. Speckmann) and H. Caspers. The present work combines new experimental and clinical results with state-of-the-art reports giving excellent general views. The first chapter presents a historical survey of the roots of current developments in neu- rophysiology. It seems that in the near future we may decipher the EEG, which we have considered up to now somewhat as a cryptogram (chap- ter 2). After chapter 3-a chapter concerned with more general points of the generation of cortical field potentials-chapters 4, 5, and 6 deal with several aspects and models of interactions and rhythms of cortical neurons. The role of glial cells in cortical electrical field generation is considered in chapter 7. Chapter 8 emphasizes the significance of brain metabolism.
This book deals with the growing challenges of using assistive robots in our everyday activities along with providing intelligent assistive services. The presented applications concern mainly healthcare and wellness such as helping elderly people, assisting dependent persons, habitat monitoring in smart environments, well-being, security, etc. These applications reveal also new challenges regarding control theory, mechanical design, mechatronics, portability, acceptability, scalability, security, etc.
Encyclopedia of Medical Devices and Instrumentation John G. Webster, Editor-in-Chief This comprehensive encyclopedia, the work of more than 400 contributors, includes 266 articles on devices and instrumentation that are currently or likely to be useful in medicine and biomedical engineering. The four volumes include 3,022 pages of text that concentrates on how technology assists the branches of medicine. The articles emphasize the contributions of engineering, physics, and computers to each of the general areas of medicine, and are designed not for peers, but rather for workers from related fields who wish to take a first look at what is important in the subject. Highly recommended for university biomedical engineering and medical reference collections, and for anyone with a science background or an interest in technology. Includes a 78-page index, cross-references, and high-quality diagrams, illustrations, and photographs. 1988 (0 471-82936-6) 4-Volume Set Introduction to Radiological Physics and Radiation Dosimetry Frank Herbert Attix provides complete and useful coverage of radiological physics. Unlike most treatments of the subject, it encompasses radiation dosimetry in general, rather than discussing only its applications in medical or health physics. The treatment flows logically from basics to more advanced topics. Coverage extends through radiation interactions to cavity theories and dosimetry of X-rays, charged particles, and neutrons. Several important subjects that have never been thoroughly analyzed in the literature are treated here in detail, such as charged-particle equilibrium, broad-beam attenuation and geometries, derivation of the Kramers X-ray spectrum, and the reciprocity theorem, which is also extended to the nonisotropic homogeneous case. 1986 (0 471-01146-0) 607 pp. Medical Physics John R. Cameron and James G. Skofronick This detailed text describes medical physics in a simple, straightforward manner. It discusses the physical principles involved in the control and functon of organs and organ systems such as the eyes, ears, lungs, heart, and circulatory system. There is also coverage of the application of mechanics, heat, light, sound, electricity, and magnetism to medicine, particularly of the various instruments used for the diagnosis and treatment of disease. 1978 (0 471-13131-8) 615 pp.
This book offers a comprehensive report on the technological aspects of Mobile Health (mHealth) and discusses the main challenges and future directions in the field. It is divided into eight parts: (1) preventive and curative medicine; (2) remote health monitoring; (3) interoperability; (4) framework, architecture, and software/hardware systems; (5) cloud applications; (6) radio technologies and applications; (7) communication networks and systems; and (8) security and privacy mechanisms. The first two parts cover sensor-based and bedside systems for remotely monitoring patients' health condition, which aim at preventing the development of health problems and managing the prognosis of acute and chronic diseases. The related chapters discuss how new sensing and wireless technologies can offer accurate and cost-effective means for monitoring and evaluating behavior of individuals with dementia and psychiatric disorders, such as wandering behavior and sleep impairments. The following two parts focus on architectures and higher level systems, and on the challenges associated with their interoperability and scalability, two important aspects that stand in the way of the widespread deployment of mHealth systems. The remaining parts focus on telecommunication support systems for mHealth, including radio technologies, communication and cloud networks, and secure health-related applications and systems. All in all, the book offers a snapshot of the state-of-art in mHealth systems, and addresses the needs of a multidisciplinary audience, including engineers, computer scientists, healthcare providers, and medical professionals, working in both academia and the industry, as well as stakeholders at government agencies and non-profit organizations.
The three-volume set LNCS 8673, 8674, and 8675 constitutes the refereed proceedings of the 17th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014, held in Boston, MA, USA, in September 2014. Based on rigorous peer reviews, the program committee carefully selected 253 revised papers from 862 submissions for presentation in three volumes. The 53 papers included in the third volume have been organized in the following topical sections: shape and population analysis; brain; diffusion MRI; and machine learning.
This book seeks to promote the exploitation of data science in healthcare systems. The focus is on advancing the automated analytical methods used to extract new knowledge from data for healthcare applications. To do so, the book draws on several interrelated disciplines, including machine learning, big data analytics, statistics, pattern recognition, computer vision, and Semantic Web technologies, and focuses on their direct application to healthcare. Building on three tutorial-like chapters on data science in healthcare, the following eleven chapters highlight success stories on the application of data science in healthcare, where data science and artificial intelligence technologies have proven to be very promising. This book is primarily intended for data scientists involved in the healthcare or medical sector. By reading this book, they will gain essential insights into the modern data science technologies needed to advance innovation for both healthcare businesses and patients. A basic grasp of data science is recommended in order to fully benefit from this book.
3D Printing in Medicine examines the emerging market of 3D-printed biomaterials and its clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The book begins with a discussion of the fundamentals of 3D printing, including topics such as materials, and hardware. Chapters go on to cover applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing and 3D cell and organ printing. The concluding chapters in the book review the applications of 3D printing in diagnostics, drug development, 3D-printed disease models and 3D printers for surgical practice. With a strong focus on the translation of 3D printing technology to a clinical setting, this book is a valuable resource for scientists and engineers working in biomaterial, biomedical, and nanotechnology based industries and academia.
This book constitutes the refereed proceedings of the 8th IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2013, held in Nice, France, in June 2013. The 25 revised full papers presented were carefully reviewed and selected from 43 submissions. The papers are organized in topical sections on bio-molecular networks and pathway analysis; learning, classification, and clustering; data mining and knowledge discovery; protein: structure, function, and interaction; motifs, sites, and sequence analysis.
The two phenomena are occurring side by side: a rapidly growing elder population and a burgeoning tech sector. Where a few years ago these worlds would not have met, a new generation of older adults has grown comfortable with technology and open to its possibilities for improving their lives as they age.
"Technologies for Active Aging" offers novel answers to a range of aging issues, from safety and mobility to cognition and continence. Written for the non-technical reader, the book examines the potential of information and communicative technologies such as pervasive computing, smart environments, and robotics to enhance seniors' quality of life and encourage independent living, better care and self-care, and social participation.
Diversity is emphasized here, in terms of the life areas addressed, the perspectives of elders and caregivers, and the global reach of those working toward solutions. This state-of-the-field volume looks ahead to future research and the next wave of innovations to help all seniors, regardless of health or ability. Among the topics featured: Promoting technology use by people with dementia.Wheelchair mobility in older adults.Intelligent systems for assessing age-related changes using home-based technology.Measuring the effectiveness of assistive technologies in community and home settings.Technology for the prevention of fall-related injuries.Tele-health in chronic disease management.
A comprehensive mix of theoretical developments and emerging realities, "Technologies for Active Aging" serves a variety of professionals, including gerontologists, sociologists, health and cross-cultural psychologists, and public health policymakers.
Wireless Body Area Networks (WBANs) are expected to promote new applications for the ambulatory health monitoring of chronic patients and elderly population, aiming to improve their quality of life and independence. These networks are composed by wireless sensor nodes (WSNs) used for measuring physiological variables (e.g., glucose level in blood or body temperature) or controlling therapeutic devices (e.g., implanted insulin pumps). These nodes should exhibit a high degree of energy autonomy in order to extend their battery lifetime or even make the node supply to rely on harvesting techniques. Typically, the power budget of WSNs is dominated by the wireless link and, hence, many efforts have been directed during the last years toward the implementation of power efficient transceivers.
Because of the short range (typically no more than a few meters) and low data rate (typically in between 10 kb/s and 1 Mb/s), simple communication protocols can be employed. One of these protocols, specifically tailored for WBAN applications, is the Bluetooth low energy (BLE) standard.
This book describes the challenges and solutions for the design of ultra-low power transceivers for WBANs applications and presents the implementation details of a BLE transceiver prototype. Coverage includes not only the main concepts and architectures for achieving low power consumption, but also the details of the circuit design and its implementation in a standard CMOS technology."
Biologics have revolutionised the treatment of many severe conditions, delivering exceptional clinical results but also producing exceptionally high prices. As patents expire, copies and price competition are expected throughout the world. However, due to the intrinsic heterogeneity and molecular complexity of biologic medicinal products, their copies cannot simply be authorized under the "generic rule" valid for small chemical entities. In response, a dedicated regulation was issued in the European Union. It is based on the concept of "biological medicinal products similar to a biological reference product", or "biosimilars". This book analyses the context of biotechnological production and addresses the European legal framework for biosimilar market approval. It highlights post-market authorisation issues, such as Risk Management Plans and substitution of products, and outlines some other issues, such as cost management and international nomenclature. This book is primarily intended for hospital-based physicians and pharmacists. It will also be a valuable resource for all actors from all countries who want to better understand the emergence of these new medicinal products within the European context.
Computational Intelligence is comparatively a new field but it has made a tremendous progress in virtually every discipline right from engineering, science, business, m- agement, aviation to healthcare. Computational intelligence already has a solid track-record of applications to healthcare, of which this book is a continuation. We would like to refer the reader to the excellent previous volumes in this series on computational intelligence in heal- care [1-3]. This book is aimed at providing the most recent advances and state of the art in the practical applications of computational intelligence paradigms in healthcare. It - cludes nineteen chapters on using various computational intelligence methods in healthcare such as intelligent agents and case-based reasoning. A number of fielded applications and case studies are presented. Highlighted are in particular novel c- putational approaches to the semantic management of health information such as in the Web 2.0, mobile agents such as in portable devices, learning agents capable of adapting to diverse clinical settings through case-based reasoning, and statistical - proaches in computational intelligence. This book is targeted towards scientists, application engineers, professors, health professionals, professors, and students. Background information on computational intelligence has been provided whenever necessary to facilitate the comprehension of a broad audience including healthcare practitioners.
This book reports cutting-edge cases of emerging health technologies.Some health care fields are experiencing paradigmatic shifts because of robotic technologies and the new relationships that they create in r-Health (r-Curing and r-Caring) activities.The book explores emerging health care technologies such as image-guided surgical robotics, pharmacy robots, new visualisation methods (3D, 4D & 5D ) and home telehealth management systems and their acceptance in the workplace but also, more generally, their special role in business and society. These technologies allow health care professionals to effectively reach far beyond the current service offerings, providing new methods for communication, diagnosis, and treatment. The relocation of certain knowledge areas from physicians to patients in self-care management or the reconfiguration of health care expertise from one health profession to another are examples of topics developed in this book. The book describes the emerging relocation of innovative visual knowledge and expertise within health care organisations and beyond, such as in the patient's home environment."
Despite all the jokes about the poor quality of physician handwriting, physician adoption of computerized provider order entry (CPOE) in hospitals still lags behind other industries' use of technology. As of the end of 2010, less than 22% of hospitals had deployed CPOE. Yet experts claim that this technology reduces over 80% of medication errors and could prevent an estimated 522,000 serious medication errors annually in the US. Even though the federal government has offered $20 billion dollars in incentives to hospitals and health systems through the 2009 stimulus (the ARRA HITECH section of the American Recovery and Reinvestment Act of 2009), many organizations are struggling to implement advanced clinical information systems including CPOE. In addition, industry experts estimate that the healthcare industry is lacking as many as 40,000 persons with expertise in clinical informatics necessary to make it all happen by the 2016 deadline for these incentives. While the scientific literature contains numerous studies and stories about CPOE, no one has written a comprehensive, practical guide like Making CPOE Work. While early adopters of CPOE were mainly academic hospitals, community hospitals are now proceeding with CPOE projects and need a comprehensive guide. Making CPOE Work is a book that will provide a concise guide to help both new and experienced health informatics teams successfully plan and implement CPOE. The book, in a narrative style, draws on the author's decade-long experiences of implementing CPOE at a variety of academic, pediatric and community hospitals across the United States.
This book constitutes the proceedings of the 7th International Conference on Persuasive Technology, PERSUASIVE 2012, held in Linkoping, Sweden, in June 2012. The 21 full papers presented together with 5 short papers were carefully reviewed and selected from numerous submissions. In addition three keynote papers are included in this volume. The papers cover the typical fields of persuasive technology, such as health, safety and education."
Laparoscopy is increasingly being used as an alternative to more invasive surgical techniques. This book details newly revealed anatomical dynamics of the lower abdominal wall and introduces the reader to laparoscopic repair of the inguinal hernia. Provides a thorough discussion of the etiology of hernias while stressing the importance of the functional shutter mechanism in preventing hernias.
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