All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the field of bioinformatics, as well as future directions. Each chapter is didactically organized and includes an introduction, applications, tools and future directions. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high throughput technologies, drug informatics, system and network biology, and machine learning. This is a valuable resource for researchers and graduate students who are interested in learning more about bioinformatics to apply tactics in their research work.

This book explores the pivotal role played by technology over the past decade in advancing global public health and health care. At present, the global community faces unprecedented healthcare challenges fueled by an aging population, rising rates of chronic disease, and persistent health disparities. New technologies and advancements have the potential to extend the reach of health professionals while improving quality and efficiency of service delivery and reducing costs within the public and the private health systems. The chapters highlight the barriers faced by the global healthcare workforce in using technology to promote health and human rights of communities: Role of Digital Health, mHealth, and Low-Cost Technologies in Advancing Universal Health Coverage in Emerging Economies Telehealth and Homecare Agencies Technology and the Practice of Health Education in Conflict Zones The Worldwide Digital Divide and Access to Healthcare Technology Technology for Creating Better Professional Teams to Strengthen Healthcare Systems Global Public Health Disaster Management and Technology As a resource on the evolution of technology as a valuable and integral component in the promotion and practice of public health and health care, with a focus on SDG 3 targets, Technology and Global Public Health should engage students, instructors, practitioners, and other professionals interested in public health, universal health care, health technology, digital health, and health equity. Dr. Murthy has been a respected leader and mentor on scientific health-related matters within the UN system for many years. Her book develops a theoretical system connecting concepts that have coined global public health with the rapid development of technology, all with the focus to achieve Sustainable Development Goal number three, within the time frame set by World Leaders. - Henry L. Mac-Donald, Former Permanent Representative of Suriname to the United Nations

Provides derivation of the models used for calculating the risk and hazard of central oxygen toxicity Improves oxygen diving procedures described in the US Navy Diving Manual Includes procedures applicable to undertaking nitrox dives in combination with oxygen dives Pitches the material at highest technology readiness levels i.e. 9 TRL Aims to increase tactical capabilities of conducting diving special operations

Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills with regard to algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that demonstrate the main principles underlying real world applications.

Music recommendation systems are becoming more and more popular. The increasing amount of personal data left by users on social media contributes to more accurate inference of the user's musical preferences and the same to quality of personalized systems. Health recommendation systems have become indispensable tools in decision making processes in the healthcare sector. Their main objective is to ensure the availability of valuable information at the right time by ensuring information quality, trustworthiness, authentication, and privacy concerns. Medical doctors deal with various kinds of diseases in which the music therapy helps to improve symptoms. Listening to music may improve heart rate, respiratory rate, and blood pressure in people with heart disease. Sound healing therapy uses aspects of music to improve physical and emotional health and well-being. The book presents a variety of approaches useful to create recommendation systems in healthcare, music, and in music therapy.

"True wellness innovation requires the recruitment of multi-disciplinary participants. This book breaks the mold with examples from healthcare experts and other professionals who have leveraged informatics to better the lives of their constituents." - Jason Helgerson, Founder & CEO, Helgerson Solutions Group LLC Developed for those training in academic centers as well as for those already "out in the field," this book looks at how attorneys, behavioral health experts, business development experts, chief information officers, chief medical officers, chief nursing information officers, consumer advocates, cryptographic experts, futurists, geneticists, informaticists, managed care executives, nurses, pharmacists, physicians, public health professionals, software developers, systems security officers, and workforce experts are collaborating on a "team-based," IT-enabled approach to improve healthcare.

Digital Transformation in Healthcare in Post-Covid19 Times discusses recent advances in patient care and offers critical comparative insights into their application across multiple domains in healthcare. By showcasing key problems, best practices and emerging challenges, the book offers a state-of-art review of opportunities and prospects in the process of delivering smart sustainable healthcare services. Topics discussed include healthcare challenges in the post-COVID-19 era, enabling technologies for digital transformation, value driven approaches to the delivery of patient centric top-quality health services, and analytics and enhanced decision making. In addition, the book updates knowledge on best practices for training towards digital transformation and sustainable health. This is a valuable resource for healthcare professionals, medical doctors, researchers, graduate students and members of the biomedical field who are interested in learning more about the use of emerging technologies in healthcare.

This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings. In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.

Computer Vision for Assistive Healthcare describes how advanced computer vision techniques provide tools to support common human needs, such as mental functioning, personal mobility, sensory functions, daily living activities, image processing, pattern recognition, machine learning and how language processing and computer graphics cooperate with robotics to provide such tools. Users will learn about the emerging computer vision techniques for supporting mental functioning, algorithms for analyzing human behavior, and how smart interfaces and virtual reality tools lead to the development of advanced rehabilitation systems able to perform human action and activity recognition. In addition, the book covers the technology behind intelligent wheelchairs, how computer vision technologies have the potential to assist blind people, and about the computer vision-based solutions recently employed for safety and health monitoring.

The concepts of telemedicine and e-healthcare have eased as well as improved the reachability of experienced doctors and medical staff to remote patients. A patient who is living in a remote village area can directly connect to specialist doctors across the globe though his/her mobile phone using telemedicine systems and e-healthcare services. In pandemic situations like COVID-19, these online platforms helped society to get medical treatment from their residence without any physical movement. Technology is transforming human lives by playing an important role in the planning, designing, and development of intelligent systems for better service. This book presents a cross-disciplinary perspective on the concept of machine learning, blockchain and IoT by congregating cutting-edge research and insights. It also identifies and discusses various advanced technologies such as internet of things (IoT), big data analytics, machine learning, artificial intelligence, cyber security, cloud computing, sensors and so on that are vital to foster the development of smart healthcare and telemedicine systems by providing effective solutions to the medical challenges faced by humankind.

This book provides a novel solution for existing challenges in wireless body sensor networks (WBAN) such as network lifetime, fault tolerant approaches, reliability, security, and privacy. The contributors first discuss emerging trends of WBAN in the present health care system. They then provide possible solutions to challenges inherent in WBANs. Finally, they discuss results in working environments. Topics include communication protocols of implanted, wearable and nano body sensor networks; energy harvesting methodologies and experimentation for WBAN; reliability analysis and fault tolerant architecture for WBAN; and handling network failure during critical duration. The contributors consist of researchers and practitioners in WBAN around the world.

This book examines the current status of mHealth development, regulations and the social background in Japan, South Korea and China, comparing it to the situation in the United States and the European Union and consider solutions to issues surrounding mHealth. The recent progress in mobile technology, represented by smartphones and smart watches, has been remarkable. A service called mobile health (mHealth), which uses such mobile technology to manage health, is also becoming a reality. Although the accuracy of medical devices is not as accurate as those used in medicine, the biometric information such as heart rate and SpO2 can already be monitored over a long period of time. Although the technology is maturing to the point where it can be implemented in society, it remains an unapproved service of medical care in most countries. The development and social implementation of mHealth is most active in the US, but social implementation is gradually progressing in other countries as well. In this book, we will first discuss what kind of global and harmonized regulations are desirable by comparing the regulatory reforms necessary for social implementation of mHealth. In addition, mHealth raises privacy concerns in the US because the usual behavior and biometric information of subjects is utilized by private companies. In addition, it is important to note that the behavior and biometric information of subjects collected by smart devices is automatically analyzed by AI technology, mainly machine learning, which makes the analysis a black box.

This book provides comprehensive coverage of the technique and clinical applications of magnetic brain stimulation. It begins with an account of the invention of the technique and considers the technical aspects of how magnetic stimulators work. The anatomy and physiology of cortical motor areas are covered in sufficient detail to interpret the findings. There then follows a discussion of the effects of magnetic brain stimulation in healthy subjects, covering the visual and motor systems, and the effects of repetitive transcranial stimulation. A chapter on the practical aspects of the technique's use in a clinical setting is followed by coverage of specific clinical applications in patients with demyelinating diseases, motoneurone diseases, cerebrovascular diseases, degenerative neurological diseases, movement disorders, spinal cord and peripheral nerve diseases. The final chapters deal with the use of brain stimulation in neurosurgical monitoring and discuss potential developments of the technique in investigating neural plasticity and in treatment of psychiatric conditions. Kerry Mills is an authority, pioneer and active worker in the field; he is uniquely positioned to review the technique, from its invention through to the very latest clinical applications.

This book presents the proceedings of the KES International Conferences on Innovation in Medicine and Healthcare (KES-InMed-19), held in Split, Croatia, on June 17-19, 2020. Covering a number of key areas, including digital IT architecture in healthcare; advanced ICT for medicine and healthcare; biomedical engineering, trends, research and technologies; and healthcare support systems, this book is a valuable resource for researchers, managers, industrialists and anyone wishing to gain an overview of the latest research in these fields.

Patient-focused healthcare, driven by COVID-19 experiences, has become a hallmark for providing healthcare services to patients across all modalities of care and in the home. The ability to capture real-time patient data, no matter the location, via remote patient monitoring, and to transmit that data to providers and organizations approved by the consumer/patient, will become a critical capability for all healthcare providers. Of all the remote patient monitoring product designs, wearable medical devices are emerging as the best positioned to support the evolving patient-focused healthcare environment. This book is for those who are evaluating, selecting, implementing, managing, or designing wearable devices to monitor the health of patients and consumers. This book will provide the knowledge to understand the issues that mitigate the risk of wearable technologies so people can deliver successful projects using these technologies. It will discuss their use in remote patient monitoring, the advantages and disadvantages of different types of physiological sensors, different wireless communication protocols, and different power sources. It will describe issues and solutions in cybersecurity and HIPAA compliance, as well as setting them up to be used in healthcare systems and by patients.

Patient-focused healthcare, driven by COVID-19 experiences, has become a hallmark for providing healthcare services to patients across all modalities of care and in the home. The ability to capture real-time patient data, no matter the location, via remote patient monitoring, and to transmit that data to providers and organizations approved by the consumer/patient, will become a critical capability for all healthcare providers. Of all the remote patient monitoring product designs, wearable medical devices are emerging as the best positioned to support the evolving patient-focused healthcare environment. This book is for those who are evaluating, selecting, implementing, managing, or designing wearable devices to monitor the health of patients and consumers. This book will provide the knowledge to understand the issues that mitigate the risk of wearable technologies so people can deliver successful projects using these technologies. It will discuss their use in remote patient monitoring, the advantages and disadvantages of different types of physiological sensors, different wireless communication protocols, and different power sources. It will describe issues and solutions in cybersecurity and HIPAA compliance, as well as setting them up to be used in healthcare systems and by patients.

The Tourniquet Manual - principles and practice provides a comprehensive and detailed account of the safe use of the tourniquet by using a physiological approach which ensures good practice. Starting from a historical background the reader learns the detailed effects of ischaemia on the vulnerable tissues, especially muscle and nerve. The effects of releasing the tourniquet on the systemic circulation and the complicated biochemistry of the ischaemia-reperfusion response are explained. Complications and good practice are discussed. There is a chapter on the latest technological advances in tourniquets. This book provides a coherent account of the subject and is an invaluable source of references. It will help avoid medicolegal problems and promote good practice by surgeons, anaesthetists and operation theatre technicians alike and should be in every theatre office.

At the cross-roads of biology, microfluidics and photonics the field of optofluidics allows for quick and compact solutions for medical and biochemical sensing and manipulation. This book is concerned with the ingredients for a polymer-based platform which is able to culture and pattern life cells for a sufficient period of time, enables the integration of photonic devices, and provides means to integrate electronic readout. Thus - in its cross-discipline approach - it touches on aspects of photonics, nanofabrication, and biological methods alike.

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine.

Describes the properties of cellular membranes and their relationship with fundamental biological processes. This book provides insight on the chemistry, structures, model systems, and techniques employed for studying membrane properties and processes. A major focus is on the prominence of membranes in diverse physiological processes and disease, as well as applications of membranes and biomimetic membrane systems in varied disciplines. The book aims to illuminate the significance and beauty of membrane science, and serve both as an entry point for scholars wishing to embark on membrane research, as well as scientists already working in the field.

A collection of cutting-edge laboratory techniques for the study of trophoblast and placental biology. The techniques presented range from experimental animal models, to animal and human placental organ and cell culture systems, to morphological, biochemical, and molecular strategies for assessing trophoblast/placental growth, differentiation and function. Volume 1 provides readily reproducible protocols for studying embryo-uterine implantation, trophoblast cell development, and the organization and molecular characterization of the placenta. Highlights include strategies for the isolation and culture of trophoblast cells from primates, ruminants, and rodents, and precise guidance to the molecular and cellular analysis of the placental phenotype. A companion second volume concentrates on methods for investigating placental function.

This book addresses various aspects of how smart healthcare can be used to detect and analyze diseases, the underlying methodologies, and related security concerns. Healthcare is a multidisciplinary field that involves a range of factors like the financial system, social factors, health technologies, and organizational structures that affect the healthcare provided to individuals, families, institutions, organizations, and populations. The goals of healthcare services include patient safety, timeliness, effectiveness, efficiency, and equity. Smart healthcare consists of m-health, e-health, electronic resource management, smart and intelligent home services, and medical devices. The Internet of Things (IoT) is a system comprising real-world things that interact and communicate with each other via networking technologies. The wide range of potential applications of IoT includes healthcare services. IoT-enabled healthcare technologies are suitable for remote health monitoring, including rehabilitation, assisted ambient living, etc. In turn, healthcare analytics can be applied to the data gathered from different areas to improve healthcare at minimum expense.

Pulsed electric fields have been applied to living systems in vitro for a host of delivery applications since the early 1980s. It has been established that the primary effect that electrical treatment has on cells is an induced increase in the permeability of membranes to exogenous molecules. This state of increased permeability was noted to be temporary and could be induced with little or no effect on cell viability. This physical phenomenon was termed electroporation. Numerous published studies have shown that electroporation can be applied to any cell type. These studies also exploited the phenomenon to deliver drugs, DNA, antibodies, proteins, and fluorescent molecules. The use of electricity to mediate delivery of these molecule types in vitro has proven to be an invaluable research tool for biological and biomedical scientists. Many of the in vitro applications for electrically mediated delivery have tremendous potential for the treatment of human disease. For example, the ef- cient delivery of drugs and plasmid DNA has strong implications for improving standard therapies, as well as gene therapies. This potential was realized about 12 years ago when electric pulses were used to deliver drugs to tumor cells in vivo. Since then, the utility of in vivo electroporation for the delivery of m- ecules has been demonstrated through new applications that have been developed with increasing frequency each year. Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery: Electrically Mediated Delivery of Molecules to Cells provides review and protocol chapters that completely cover this relatively new scientific discipline.

This book introduces the field of Health Web Science and presents methods for information gathering from written social media data. It explores the availability and utility of the personal medical information shared on social media platforms and determines ways to apply this largely untapped information source to healthcare systems and public health monitoring. Introducing an innovative concept for integrating social media data with clinical data, it addresses the crucial aspect of combining experiential data from social media with clinical evidence, and explores how the variety of available social media content can be analyzed and implemented. The book tackles a range of topics including social media's role in healthcare, the gathering of shared information, and the integration of clinical and social media data. Application examples of social media for health monitoring, along with its usage in patient treatment are also provided. The book also considers the ethical and legal issues of gathering and utilizing social media data, along with the risks and challenges that must be considered when integrating social media data into healthcare choices. With an increased interest internationally in E-Health, Health 2.0, Medicine 2.0 and the recent birth of the discipline of Web Science, this book will be a valuable resource for researchers and practitioners investigating this emerging topic.