Membrane processes today play a signifi cant role in the replacement therapy for acute and chronic organ failure diseases. Current extracorporeal blood purifi cation and oxygenation devices employ membranes acting as selective barriers for the removal of endogeneous and exogeneous toxins and for gas exchange, respectively. Additionally, membrane technology offers new interesting opportunities for the design of bioartificial livers, pancreas, kidneys, lungs etc. This book reviews the latest developments in membrane systems for bioartificial organs and regenerative medicine, investigates how membrane technology can improve the quality and efficiency of biomedical devices, and highlights the design procedures for membrane materials covering the preparation, characterization, and sterilization steps as well as transport phenomena. The different strategies pursued for the development of membrane bioartifi cial organs, including crucial issues related to blood/cell-membrane interactions are described with the aim of opening new and exciting frontiers in the coming decades. The book is a valuable tool for tissue engineers, clinicians, biomaterials scientists, membranologists as well as biologists and biotechnologists. It is also a source of reference for students, academic and industrial researchers in the topic of biotechnology, biomedical engineering, materials science and medicine.

Basic Biostatistics for Medical and Biomedical Practitioners, Second Edition makes it easier to plan experiments, with an emphasis on sample size. It also shows what choices are available when simple tests are unsuitable and offers investigators an overview of how the kinds of complex tests that they won't do on their own work. The second edition presents a new, revised and enhanced version of the chapters, taking into consideration new developments and tools available, discussing topics, such as the basic aspects of statistics, continuous distributions, hypothesis testing, discrete distributions, probability in epidemiology and medical diagnosis, comparing means, regression and correlation. This book is a valuable source for students and researchers looking to expand or refresh their understanding of statistics as it applies to the biomedical and research fields. Based on the author's 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields, it is a valuable source for researchers who need to understand more about biostatistics to apply it to their work.

The Transformative Power of Mobile Medicine: Leveraging Innovation, Seizing Opportunities, and Overcoming Obstacles of mHealth addresses the rapid advances taking place in mHealth and their impact on clinicians and patients. It provides guidance on reliable mobile health apps that are based on sound scientific evidence, while also offering advice on how to stay clear of junk science. The book explores the latest developments, including the value of blockchain, the emerging growth of remote sensors in chronic patient care, the potential use of Amazon Alexa and Google Assistant as patient bedside assistants, the use of Amazon's IoT button, and much more. This book enables physicians and nurses to gain a deep understanding of the strengths and weaknesses of mobile health and helps them choose evidence-based mobile medicine tools to improve patient care.

Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data.

The COVID-19 pandemic has highlighted the importance of health data, technology, and access to health informatics. The applications of several information technologies in the context of healthcare are proving instrumental in pandemic control. These technologies were already actively used in the healthcare sector before the pandemic. However, the pandemic has resulted in researchers reassessing how these technologies could have better assisted with the aftermath of the COVID-19 pandemic and how they may mitigate the threat of future pandemics. Health Informatics and Patient Safety in Times of Crisis provides a fresh perspective on how healthcare informatics has managed the current pandemic and how improved healthcare informatics could help in a future crisis. Covering topics such as digital public health, misinformation, and knowledge management, this premier reference source is an indispensable resource for medical professionals, hospital administrators, public health officials, community leaders, international leaders, libraries, medical students, medical professors, researchers, and academicians.

This book fosters a scientific debate for sophisticated approaches and cognitive technologies (such as deep learning, machine learning and advanced analytics) for enhanced healthcare services in light of the tremendous scope in the future of intelligent systems for healthcare. The authors discuss the proliferation of huge data sources (e.g. genomes, electronic health records (EHRs), mobile diagnostics, and wearable devices) and breakthroughs in artificial intelligence applications, which have unlocked the doors for diagnosing and treating multitudes of rare diseases. The contributors show how the widespread adoption of intelligent health based systems could help overcome challenges, such as shortages of staff and supplies, accessibility barriers, lack of awareness on certain health issues, identification of patient needs, and early detection and diagnosis of illnesses. This book is a small yet significant step towards exploring recent advances, disseminating state-of-the-art techniques and deploying novel technologies in intelligent healthcare services and applications. Describes the advances of computing methodologies for life and medical science data; Presents applications of artificial intelligence in healthcare along with case studies and datasets; Provides an ideal reference for medical imaging researchers, industry scientists and engineers, advanced undergraduate and graduate students, and clinicians.

Intelligent Speech Signal Processing investigates the utilization of speech analytics across several systems and real-world activities, including sharing data analytics, creating collaboration networks between several participants, and implementing video-conferencing in different application areas. Chapters focus on the latest applications of speech data analysis and management tools across different recording systems. The book emphasizes the multidisciplinary nature of the field, presenting different applications and challenges with extensive studies on the design, development and management of intelligent systems, neural networks and related machine learning techniques for speech signal processing.

This book explores the pivotal role played by technology over the past decade in advancing global public health and health care. At present, the global community faces unprecedented healthcare challenges fueled by an aging population, rising rates of chronic disease, and persistent health disparities. New technologies and advancements have the potential to extend the reach of health professionals while improving quality and efficiency of service delivery and reducing costs within the public and the private health systems. The chapters highlight the barriers faced by the global healthcare workforce in using technology to promote health and human rights of communities: Role of Digital Health, mHealth, and Low-Cost Technologies in Advancing Universal Health Coverage in Emerging Economies Telehealth and Homecare Agencies Technology and the Practice of Health Education in Conflict Zones The Worldwide Digital Divide and Access to Healthcare Technology Technology for Creating Better Professional Teams to Strengthen Healthcare Systems Global Public Health Disaster Management and Technology As a resource on the evolution of technology as a valuable and integral component in the promotion and practice of public health and health care, with a focus on SDG 3 targets, Technology and Global Public Health should engage students, instructors, practitioners, and other professionals interested in public health, universal health care, health technology, digital health, and health equity. Dr. Murthy has been a respected leader and mentor on scientific health-related matters within the UN system for many years. Her book develops a theoretical system connecting concepts that have coined global public health with the rapid development of technology, all with the focus to achieve Sustainable Development Goal number three, within the time frame set by World Leaders. - Henry L. Mac-Donald, Former Permanent Representative of Suriname to the United Nations

Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills with regard to algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that demonstrate the main principles underlying real world applications.

Music recommendation systems are becoming more and more popular. The increasing amount of personal data left by users on social media contributes to more accurate inference of the user's musical preferences and the same to quality of personalized systems. Health recommendation systems have become indispensable tools in decision making processes in the healthcare sector. Their main objective is to ensure the availability of valuable information at the right time by ensuring information quality, trustworthiness, authentication, and privacy concerns. Medical doctors deal with various kinds of diseases in which the music therapy helps to improve symptoms. Listening to music may improve heart rate, respiratory rate, and blood pressure in people with heart disease. Sound healing therapy uses aspects of music to improve physical and emotional health and well-being. The book presents a variety of approaches useful to create recommendation systems in healthcare, music, and in music therapy.

This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings. In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.

Computer Vision for Assistive Healthcare describes how advanced computer vision techniques provide tools to support common human needs, such as mental functioning, personal mobility, sensory functions, daily living activities, image processing, pattern recognition, machine learning and how language processing and computer graphics cooperate with robotics to provide such tools. Users will learn about the emerging computer vision techniques for supporting mental functioning, algorithms for analyzing human behavior, and how smart interfaces and virtual reality tools lead to the development of advanced rehabilitation systems able to perform human action and activity recognition. In addition, the book covers the technology behind intelligent wheelchairs, how computer vision technologies have the potential to assist blind people, and about the computer vision-based solutions recently employed for safety and health monitoring.

All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the field of bioinformatics, as well as future directions. Each chapter is didactically organized and includes an introduction, applications, tools and future directions. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high throughput technologies, drug informatics, system and network biology, and machine learning. This is a valuable resource for researchers and graduate students who are interested in learning more about bioinformatics to apply tactics in their research work.

The concepts of telemedicine and e-healthcare have eased as well as improved the reachability of experienced doctors and medical staff to remote patients. A patient who is living in a remote village area can directly connect to specialist doctors across the globe though his/her mobile phone using telemedicine systems and e-healthcare services. In pandemic situations like COVID-19, these online platforms helped society to get medical treatment from their residence without any physical movement. Technology is transforming human lives by playing an important role in the planning, designing, and development of intelligent systems for better service. This book presents a cross-disciplinary perspective on the concept of machine learning, blockchain and IoT by congregating cutting-edge research and insights. It also identifies and discusses various advanced technologies such as internet of things (IoT), big data analytics, machine learning, artificial intelligence, cyber security, cloud computing, sensors and so on that are vital to foster the development of smart healthcare and telemedicine systems by providing effective solutions to the medical challenges faced by humankind.

This book provides a novel solution for existing challenges in wireless body sensor networks (WBAN) such as network lifetime, fault tolerant approaches, reliability, security, and privacy. The contributors first discuss emerging trends of WBAN in the present health care system. They then provide possible solutions to challenges inherent in WBANs. Finally, they discuss results in working environments. Topics include communication protocols of implanted, wearable and nano body sensor networks; energy harvesting methodologies and experimentation for WBAN; reliability analysis and fault tolerant architecture for WBAN; and handling network failure during critical duration. The contributors consist of researchers and practitioners in WBAN around the world.

This book examines the current status of mHealth development, regulations and the social background in Japan, South Korea and China, comparing it to the situation in the United States and the European Union and consider solutions to issues surrounding mHealth. The recent progress in mobile technology, represented by smartphones and smart watches, has been remarkable. A service called mobile health (mHealth), which uses such mobile technology to manage health, is also becoming a reality. Although the accuracy of medical devices is not as accurate as those used in medicine, the biometric information such as heart rate and SpO2 can already be monitored over a long period of time. Although the technology is maturing to the point where it can be implemented in society, it remains an unapproved service of medical care in most countries. The development and social implementation of mHealth is most active in the US, but social implementation is gradually progressing in other countries as well. In this book, we will first discuss what kind of global and harmonized regulations are desirable by comparing the regulatory reforms necessary for social implementation of mHealth. In addition, mHealth raises privacy concerns in the US because the usual behavior and biometric information of subjects is utilized by private companies. In addition, it is important to note that the behavior and biometric information of subjects collected by smart devices is automatically analyzed by AI technology, mainly machine learning, which makes the analysis a black box.

Digital Transformation in Healthcare in Post-Covid19 Times discusses recent advances in patient care and offers critical comparative insights into their application across multiple domains in healthcare. By showcasing key problems, best practices and emerging challenges, the book offers a state-of-art review of opportunities and prospects in the process of delivering smart sustainable healthcare services. Topics discussed include healthcare challenges in the post-COVID-19 era, enabling technologies for digital transformation, value driven approaches to the delivery of patient centric top-quality health services, and analytics and enhanced decision making. In addition, the book updates knowledge on best practices for training towards digital transformation and sustainable health. This is a valuable resource for healthcare professionals, medical doctors, researchers, graduate students and members of the biomedical field who are interested in learning more about the use of emerging technologies in healthcare.

This book presents the proceedings of the KES International Conferences on Innovation in Medicine and Healthcare (KES-InMed-19), held in Split, Croatia, on June 17-19, 2020. Covering a number of key areas, including digital IT architecture in healthcare; advanced ICT for medicine and healthcare; biomedical engineering, trends, research and technologies; and healthcare support systems, this book is a valuable resource for researchers, managers, industrialists and anyone wishing to gain an overview of the latest research in these fields.

A comprehensive survey of technological developments in Virtual Reality for use in a variety of medical procedures

Medicine and the biological sciences have long relied on visualizations to illustrate the relationship between anatomic structure and biologic function. The new multidimensional imaging modalities are powerful counterparts to traditional forms of observation–surgery, postmortem examination, or extensive mental reconstruction. VR technologies have reached unimagined levels of sophistication and utility, giving physicians and students new avenues for planning and practicing surgery and diagnostics.

The two volumes of Information Technologies in Medicine thoroughly explore the use of VR technology in three-dimensional visualization techniques, realistic surgical training prior to patient contact, and actual procedures in rehabilitation and treatment, including telemedicine and telesurgery. Editors Akay and Marsh have brought together all the available information on the subject of VR technologies in medicine and medical training to create the first comprehensive guide to the state of the art in medicine for use by students, doctors, and researchers.

Volume II concentrates on VR technologies specifically in the area of rehabilitation and treatment and provides complete coverage of the most recent advancements in high-tech medicine. Specific treatments include:

• VR in neuro/orthopedic rehabilitation
• VR in treatment of anxiety disorders
• Robot-assisted microsurgery
• VR and the vestibular system
• Maxillofacial virtual surgery

The Tourniquet Manual - principles and practice provides a comprehensive and detailed account of the safe use of the tourniquet by using a physiological approach which ensures good practice. Starting from a historical background the reader learns the detailed effects of ischaemia on the vulnerable tissues, especially muscle and nerve. The effects of releasing the tourniquet on the systemic circulation and the complicated biochemistry of the ischaemia-reperfusion response are explained. Complications and good practice are discussed. There is a chapter on the latest technological advances in tourniquets. This book provides a coherent account of the subject and is an invaluable source of references. It will help avoid medicolegal problems and promote good practice by surgeons, anaesthetists and operation theatre technicians alike and should be in every theatre office.

Designing Healthcare That Works: A Sociotechnical Approach takes up the pragmatic, messy problems of designing and implementing sociotechnical solutions which integrate organizational and technical systems for the benefit of human health. The book helps practitioners apply principles of sociotechnical design in healthcare and consider the adoption of new theories of change. As practitioners need new processes and tools to create a more systematic alignment between technical mechanisms and social structures in healthcare, the book helps readers recognize the requirements of this alignment. The systematic understanding developed within the book's case studies includes new ways of designing and adopting sociotechnical systems in healthcare. For example, helping practitioners examine the role of exogenous factors, like CMS Systems in the U.S. Or, more globally, helping practitioners consider systems external to the boundaries drawn around a particular healthcare IT system is one key to understand the design challenge. Written by scholars in the realm of sociotechnical systems research, the book is a valuable source for medical informatics professionals, software designers and any healthcare providers who are interested in making changes in the design of the systems.

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines.

At the cross-roads of biology, microfluidics and photonics the field of optofluidics allows for quick and compact solutions for medical and biochemical sensing and manipulation. This book is concerned with the ingredients for a polymer-based platform which is able to culture and pattern life cells for a sufficient period of time, enables the integration of photonic devices, and provides means to integrate electronic readout. Thus - in its cross-discipline approach - it touches on aspects of photonics, nanofabrication, and biological methods alike.

Describes the properties of cellular membranes and their relationship with fundamental biological processes. This book provides insight on the chemistry, structures, model systems, and techniques employed for studying membrane properties and processes. A major focus is on the prominence of membranes in diverse physiological processes and disease, as well as applications of membranes and biomimetic membrane systems in varied disciplines. The book aims to illuminate the significance and beauty of membrane science, and serve both as an entry point for scholars wishing to embark on membrane research, as well as scientists already working in the field.

Provides derivation of the models used for calculating the risk and hazard of central oxygen toxicity Improves oxygen diving procedures described in the US Navy Diving Manual Includes procedures applicable to undertaking nitrox dives in combination with oxygen dives Pitches the material at highest technology readiness levels i.e. 9 TRL Aims to increase tactical capabilities of conducting diving special operations