This handbook covers Electronic Medical Record (EMR) systems, which enable the storage, management, and sharing of massive amounts of demographic, diagnosis, medication, and genomic information. It presents privacy-preserving methods for medical data, ranging from laboratory test results to doctors' comments. The reuse of EMR data can greatly benefit medical science and practice, but must be performed in a privacy-preserving way according to data sharing policies and regulations. Written by world-renowned leaders in this field, each chapter offers a survey of a research direction or a solution to problems in established and emerging research areas. The authors explore scenarios and techniques for facilitating the anonymization of different types of medical data, as well as various data mining tasks. Other chapters present methods for emerging data privacy applications and medical text de-identification, including detailed surveys of deployed systems. A part of the book is devoted to legislative and policy issues, reporting on the US and EU privacy legislation and the cost of privacy breaches in the healthcare domain. This reference is intended for professionals, researchers and advanced-level students interested in safeguarding medical data.

Despite all the jokes about the poor quality of physician handwriting, physician adoption of computerized provider order entry (CPOE) in hospitals still lags behind other industries' use of technology. As of the end of 2010, less than 22% of hospitals had deployed CPOE. Yet experts claim that this technology reduces over 80% of medication errors and could prevent an estimated 522,000 serious medication errors annually in the US. Even though the federal government has offered $20 billion dollars in incentives to hospitals and health systems through the 2009 stimulus (the ARRA HITECH section of the American Recovery and Reinvestment Act of 2009), many organizations are struggling to implement advanced clinical information systems including CPOE. In addition, industry experts estimate that the healthcare industry is lacking as many as 40,000 persons with expertise in clinical informatics necessary to make it all happen by the 2016 deadline for these incentives. While the scientific literature contains numerous studies and stories about CPOE, no one has written a comprehensive, practical guide like Making CPOE Work. While early adopters of CPOE were mainly academic hospitals, community hospitals are now proceeding with CPOE projects and need a comprehensive guide. Making CPOE Work is a book that will provide a concise guide to help both new and experienced health informatics teams successfully plan and implement CPOE. The book, in a narrative style, draws on the author's decade-long experiences of implementing CPOE at a variety of academic, pediatric and community hospitals across the United States.

This new edition outlines the design and implementation of an effective respiratory protective equipment program for industries in which workers are at risk from inhaled particulates, toxins and other hazardous materials. The book is intended for managers, health and safety committees, safety specialists and occupational health professionals who need the most up-to-date and practical advice in a concise and easy to read step-by-step form rather than an abstract and theoretical reference on the subject.
As in the first edition, the authors present individual components of a respiratory protection program by including chapters on the respiratory tract and how toxic substances affect the lung, different respirator types and their limitations, the criteria for selection, fitting, supervision, training, cleaning, administration and medical assessment, advice on how to set up an RPE (respiratory protection equipment) program, and case studies to illustrate the need of an effective RPE program in the workplace. An impressive number of new research and application related publications have been reviewed since the publication of the first edition. The references (including relevant web sites) and abstracts of these publications have been included to help the reader select appropriate resources for further reading.
Experts guide you through the complex data presented to industries by OSHA, NIOSH, ANSI, BSI and other health and safety standards setting organizations and equipment manufacturersSaves time and effort in searching official OEM literatureSeveral case studies to illustrate the improper respirator selections and resulting detrimental effects

This handbook provides insights into becoming a better and more evolved athlete. It offers aspiring athletes, regardless of skill level, a better understanding of their bodies and how to unlock the unlimited potential of muscles without injury. It focuses on the "superhero" muscle: the iliopsoas, and also sheds light on Diamond-Corporation's new technology and elite athleticism, and how these can contribute to a healthier life. Lastly, the authors explore the mindset of success and provide exercises for remaining calm under pressure. This stand-alone book is the sequel to Paradigm Shift for Future Tennis and Enhancing Performance and Reducing Stress in Sport (2014, Springer). This book is written by scientists, whose expertise collectively spans the fields of biomechanics, clinical surgery, current and former elite athleticism, engineering and naturopath doctoral work. Together, they aim to inspire and educate athletes on how to improve their sports performance by using new technologies, world class biomechanics knowledge and ancient herbal medicines.

This is a meticulously detailed chronological record of significant events in the history of medical informatics and their impact on direct patient care and clinical research, offering a representative sampling of published contributions to the field. The History of Medical Informatics in the United States has been restructured within this new edition, reflecting the transformation medical informatics has undergone in the years since 1990. The systems that were once exclusively institutionally driven - hospital, multihospital, and outpatient information systems - are today joined by systems that are driven by clinical subspecialties, nursing, pathology, clinical laboratory, pharmacy, imaging, and more. At the core is the person - not the clinician, not the institution - whose health all these systems are designed to serve. A group of world-renowned authors have joined forces with Dr Marion Ball to bring Dr Collen's incredible work to press. These recognized leaders in medical informatics, many of whom are recipients of the Morris F. Collen Award in Medical Informatics and were friends of or mentored by Dr Collen, carefully reviewed, editing and updating his draft chapters. This has resulted in the most thorough history of the subject imaginable, and also provides readers with a roadmap for the subject well into later in the century.

This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Adaptive Structural Systems with Piezoelectric Transducer Circuitry provides a comprehensive discussion on the integration of piezoelectric transducers with electrical circuitry for the development and enhancement of adaptive structural systems.

Covering a wide range of interdisciplinary research, this monograph presents a paradigm of taking full advantage of the two-way electro-mechanical coupling characteristics of piezoelectric transducers for structural control and identification in adaptive structural systems. Presenting descriptions of algorithm development, theoretical analysis and experimental investigation, engineers and researchers alike will find this a valuable reference.

Polymer Based Drug Delivery Systems; E. Piskin. Recent Advances and Industrial Applications of Microencapsulation; S. Benita. Recent Advances in Nanoparticles and Nanospheres; J. Kreuter. Evaluation and Formulation of Biodegradable Levodopa Microspheres Using 32 Factorial Design; B. Arica, et al. Surface-Modified Phospholipid-Stabilized Emulsions as Targeted Systems for Inhibition of Metastatic Cancer; M.J. Groves, X. Gao. Physical Characterization and Stability of a Microemulsion for Potential Oral Administration of a Peptide; A. Turkyilmaz, et al. Urea Permeation through Complex Coacervate Membranes; S. Peker, et al. Bacterial Polyhydroxyalkanoates: Biosynthesis, Screening and Characterization; I. Gursel, N.G. Alaeddinoglu. Antibiotic Release from Biodegradable PHV Microparticles; D. Sendil, et al. Drug Carrier Systems for Biotechnology Derived Products; F. OEner. Tissue Engineering of Liver; Y.M. Elcin. An In-depth Characterization of BHK Cell Lines; A. Stacey, et al. Investigation of Biological and Polymeric Material Using Atomic Force Microscopy; H. Zareie, et al. The Future Potential for the Use of Adjuvants in Human Vaccines; D. Stewart-Tull. 11 Additional Articles. Index.

The field of fibre optics is an interdisciplinary one, involving aspects of science, engineering and medicine. Some who work in this field are scientists interested in physics of optical fibers, or chemists interested in the optical triggering of certain chemicals. Engineers may be attracted to the challenge of new problems in designing and making laser and fiber systems. Among physicians, some are interested in the more scientific aspects of laser tissue interactions and in animal experiments; others are more interested in the implementation of these techniques on patients.;The increasing use of fibre optics in the field of medicine has created a need for an interdisciplinary perspective of the technology and methods for physicians as well as engineers and biophysicists. This book presents a comprehensive examination of lasers and optical fibers in an hierarchical, three-tier system. Each chapter is divided into three basic sections: the fundamentals section provides an overview of basic concepts and background, the principles section offers an in-depth engineering approach, and the advances section features specific information on systems and biophysical parameters. All those int

Computational intelligence techniques are gaining momentum in the medical prognosis and diagnosis. This volume presents advanced applications of machine intelligence in medicine and bio-medical engineering. Applied methods include knowledge bases, expert systems, neural networks, neuro-fuzzy systems, evolvable systems, wavelet transforms, and specific internet applications. The volume is written in view of explaining to the practitioner the fundamental issues related to computational intelligence paradigms and to offer a fast and friendly-managed introduction to the most recent methods based on computer intelligence in medicine.

The basic language of biology and medicine seems strange, and it should--it is essentially a foreign language, filled with words of Latin and Greek origin, diseases that are identified named after the physician who discovered it rather than the cause or effect, and is otherwise made up of abbreviations and other obscure terminology and information that only a trained physician or researcher would know. Yet many professionals are required to have at least a rudimentary knowledge of biomedical terminology and information, and frequently they are at a loss in understanding even the simplest concepts and terms. For example, how would an engineer know how the various systems of the body work together as an organism? Would a nurse know the difference between the acetabulum and acetylcholine? How can a lawyer or journalist become familiar with common clinical abbreviations and terminology? How can a patient understand his or her own medical record?

The Biomedical Desk Reference is intended to be a handy, easy-to-reach for compilation of useful biomedical terminology. The volume contains the following sections: Basic Anatomical vocabulary and Physiologic Concepts; Basic Medical and Physiologic Terminology; Common Clinical Abbreviations; Terms Commonly Used in Health-Care Administration, Insurance, and Legal Settings; Biomedical Eponyms; Medical Prefixes and Suffixes; Synopsis of Major Diseases, Drugs, and Treatments; The Anatomy of the Medical Record. Biomedical Desk Reference also contains a wealth of appendices showing conversion charts, common vital signs, laboratory values of physiologic importance, useful physical constants, definitions, and formulae.

This comprehensive referencebook will be useful for biomedical engineers, lawyers and legal secretaries, physician's assistants, medical secretaries, nurses, biomedical technicians, laboratory technicians, hospital administrators, ward clerks, aides, and other medical laypersons.

A careful review of the literature covering various aspects of applications of lasers in science and technology reveals that lasers are being applied very widely throughout the entire gamut of physical medicine. After surveying the current developments taking place in the field of medical applications of lasers, it was considered appropriate to bring together these efforts of international research scientists and experts into one volume. It is with this aim that the editors have prepared this volume which brings current research and recent developments to the attention of a wide spectrum of readership associated with hospitals, medical institutions and universities world wide, including also the medical instrument industry. Both teachers and students in the medical faculties will especially find this compendium quite useful. This book is comprised of eleven chapters. All of the important medical applications of lasers are featured. The editors have made every effort that individual chapters are self-contained and written by experts. Emphasis has been placed on straight and simple presentation of the subject matter so that even the new entrants into the field will find the book of value.

It is a tragic paradox of American health care: a system renowned for world-class doctors, the latest medical technologies, and miraculous treatments has shocking inadequacies when it comes to the health of the urban poor. Urban Health Knowledge Management outlines bold, workable strategies for addressing this disparity and eliminating the "knowledge islands" that so often disrupt effective service delivery. The book offers a wide-reaching global framework for organizational competence leading to improved care quality and outcomes for traditionally underserved clients in diverse, challenging settings. Its contributors understand the issues fluently, imparting both macro and micro concepts of KM with clear rationales and real-world examples as they: * Analyze key aspects of KM and explains their applicability to urban health. * Introduce the KM tools and technologies most relevant to health care delivery. * Offer evidence of the role of KM in improving clinical efficacy and executive decision-making. * Provide extended case examples of KM-based programs used in Washington, D.C. (child health), South Africa (HIV/AIDS), and Australia (health inequities). * Apply KM principles to urban health needs in developing countries. * Discuss new approaches to managing, evaluating, and improving delivery systems in the book's "Measures and Metrics" section. Urban health professionals, as well as health care executives and administrators, will find Urban Health Knowledge Management a significant resource for bringing service delivery up to speed at a time of great advancement and change.

"After decades of research on dysfunctional eating and lack of physical activity, research attention has finally turned to the role of digital technology in eating behaviors and eating disorders. This timely volume offers a thoughtful and wide collection of chapters discussing the possible effects of digital technologies, from those enhancing healthy eating behaviors to those that encourage disordered eating. Highly recommended for both professionals and scholars." Prof. Giuseppe Riva, Universita Cattolica del Sacro Cuore, Milan, Italy. This book examines in depth the multifaceted roles of digital technologies in the eating behaviors and eating disorders. Coverage reflects a broad theoretical and empirical knowledge of current trends in digital technology use in health behaviors, and their risks and benefits affecting wellbeing, with focus on eating behaviors and eating disorders. The authors use both qualitative and quantitative data to focus on the digital lived experiences of people and their eating related behaviors. Among the topics covered: The quality of eating-oriented information online Technology, body image, and disordered eating Eating-oriented online groups Using mobile technology in eating behaviors Usage of digital technology among people with eating disorders What healthcare professionals should know about digital technologies and eating disorders Technology-based prevention and treatment programs for eating disorders A potential source of discussion and debate in various fields across the social sciences, the health sciences, and psychology, Digital Technology, Eating Behaviors, and Eating Disorders will be especially useful to students, academics, researchers, and professionals working in the fields of eating behaviors and eating disorders.

Biomedical Engineering is defined as the science that integrates medical and engineering sciences to improve diagnosis and treatment of patients. Only by this integration progress can be achieved. Both medical and engineering sciences comprise a huge diversity in topics, so it is imaginable that Biomedical Engineering, combining these two science areas, is even more huge. Thanks to this megadisciplinary approach many breakthroughs can be achieved. More and more research groups realize this and start new research projects, which results in a rapid increase in knowledge in Biomedical Engineering. This will only benefit the main goal of Biomedical Engineering; improving diagnosis and treatment of patients when it is spread and applied. The 2nd Regensburg Applied Biomechanics conference is special in that it realized both the distribution of new knowledge and the essential integration of medical and engineering specialists. The conference dealt with the latest results in applied biomechanics, ranging from fundamental bone strength properties via bone remodeling phenomena to new implants that replace lost human functions. Also new research areas like robot surgery and tissue engineering were discussed.

The Microsystems Series has as its goal the creation of an outstanding set of textbooks, references, and monographs on subjects that span the broad field of microsystems. Exceptional PhD dissertations provide a good starting point for such a series, because, unlike monographs by more senior authors, which must compete with other professional duties for attention, the dissertation becomes the sole focus of the author until it is completed. Conversion to book form is then a streamlined process, with final editing and book production completed within a few months. Thus we are able to bring important and timely material into book form at a pace which tracks this rapidly developing field. Our first four books in the series were drawn from the more physics-oriented side of the microsystems field, including such diverse subjects as computer-aided design, atomic-force microscopy, and ultrasonic motion detection. Now, with Sangeeta Bhatia's work, we enter the realm of biology. Her use of artifically structured substrates to encourage the liver cells to form orderly assemblies is a fine example of how microfabrication technology can contribute to cell biology and medicine. I am pleased to be able to add this very new and very interesting work to the Microsystems Series. Stephen D. Senturia Cambridge MA Microfabrication in Tissue Engineering and Bioartificial Organs Foreword One of the emerging applications of microsystems technology in biology and medicine is in the field of tissue engineering and artificial organs. In order to function, cells need to receive proper signals from their environment.

The NATO Advanced Study Institute "Biomedical Optical Instrumentation and Laser Assisted Biotechnology" was held November 10-22, 1995 in Erice, Sicily. This was the 19 th conference organized by the International School of Quantum Electronics, under the auspices of the "Ettore Majorana" Center for Scientific Culture. The contributions presented at the Institute are written as extended, review-like papers to provide a broad and representative coverage of the fields of laser techniques, optoelectronics systems for medical diagnosis, and light and laser applications to Biology and Medicine. The aim of the Institute was to bring together some of the world's acknowledged scientists and clinicians that belong to different disciplines and consequently do not usually meet, but who have as a common link the use of optoelectronics instrumentation, techniques and procedures. Most of the lecturers attended all the lectures and devoted their spare hours to stimulating discussions. We would like to thank them all for their admirable contributions. The Institute also took advantage of a very active audience; most of the participants were active researchers in the field and contributed with discussions and seminars. Some of these seminars are also included in these Proceedings. The Institute was an important opportunity to discuss latest developments and emerging perspectives on the use of laser sources and optoelectronic techniques for diagnostic and therapeutic purposes."

The medical device and drug industries standards in analytical methodology and are consistently among the strongest techno- quality control. logical performers. Materials are a key The users of Biomaterials Engineering ingredient in their dynamic growth. Devel- and Devices: Human Applications will r- opment of these materials is in a constant resent a broad base of backgrounds ranging state of activity, with the challenge of re- from the basic sciences (e. g. , polymer placing old materials that cannot withstand chemistry and biochemistry) to more the tests of time, and the new materials' applied disciplines (e. g. , mechanical/ needs coming to the forefront in modern chemical engineering, orthopedics, and applications. This new reference text, pharmaceutics). To meet varied needs, each Biomaterials Engineering and Devices: chapter provides clear ancd fully detailed Human Applications, focuses on materials discussions. This in-depth, but practical, used in or on the human body-materials coverage should also assist recent indu- that define the world of "biomaterials. " ees to the biomaterials circle. The editors Biomaterials Engineering and Devices: trust that this reference textbook conveys Human Applications focuses on mate- the intensity of this fast moving field in an rials development and characterization. enthusastic presentation. Chapters deal with issues in the selection of Donald L. Wise, PHD proper biomaterials from biocompatibility Debra J. Trantolo, PHD to biostability to structure/function relation- Kai-Uwe Lewandrowski, MD ships. Chapters also focus on the use of Joseph D. Gresser, PHD specific biomaterials based on their physio- Mario V.

The goal of tissue engineering is to repair or replace tissues and organs by delivering implanted cells, scaffolds, DNA, proteins, and/or protein fragments at surgery. Tissue engineering merges aspects of engineering and biology, and many rapid achievements in this field have arisen in part from significant advances in cell and molecular biology. Functional Tissue Engineering addresses the key issues in repairing and replacing load-bearing structures effectively. What are the thresholds of force, stress, and strain that normal tissues transmit or encounter? What are the mechanical properties of these tissues when subjected to expected in vivo stresses and strains, as well as under failure conditions? Do tissue engineered repairs and replacements need to exactly duplicate the structure and function of the normal tissue or organ? When developing these implants in culture, how do physical factors such as mechanical stress regulate cell behavior in bioreactors as compared to signals experienced in vivo? And finally, can tissue engineers mechanically stimulate these implants before surgery to produce a better repair outcome? Chapters written by well-known researchers discuss these matters and provide guidelines and a summary of the current state of technology. Functional Tissue Engineering will be useful to students and researchers as it will remind tissue engineers of the clinical importance of restoring function to damaged tissue and structures. Further, the book clarifies the identification of critical structural and mechanical requirements needed for each construct. Functional Tissue Engineering also provides an invaluable resource to help tissue engineers incorporate these functional criteria into the design, manufacture, and optimization of tissue engineered products. Finally it serves as a reference and teaching text for the rapidly increasing population of students and investigators in the field of tissue engineering.

This monograph explores Intrabody communication (IBC) as a novel non-RF wireless data communication technique using the human body itself as the communication channel or transmission medium. In particular, the book investigates Intrabody Communication considering limb joint effects within the transmission frequency range 0.3-200 MHz. Based on in-vivo experiments which determine the effects of size, situations, and locations of joints on the IBC, the book proposes a new IBC circuit model explaining elbow joint effects. This model not only takes the limb joint effects of the body into account but also considers the influence of measurement equipment in higher frequency band thus predicting signal attenuation behavior over wider frequency ranges. Finally, this work proposes transmitter and receiver architectures for intrabody communication. A carrier-free scheme based on impulse radio for the IBC is implemented on a FPGA.

Like many words, the term "immunomics" equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism - be that virus, bacteria, fungus, or parasite - or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.

Bioinformatics and Drug Discovery describes the bioinformatic approaches and techniques employed along the pipeline of drug development from genes to proteins to drugs. The book focuses on gene microarray analysis and techniques for target identification and validation. In addition, clinical applications showing how the analysis can be used for prognostication and diagnosis are described. The second section focuses on protein analysis, including target validation and identification using modern proteomic analysis as well as protein modeling techniques. The third section discusses chemoinformatics, including virtual screening and how to computationally approach chemical space.

In the last two centuries, medicine has been transformed by a number of major technological and organisational innovations. This edited collection examines the role of medical technologies in the history of medicine, of new diagnostic and therapeutic tools, prostheses and apparatus. The volume also discusses the social, cultural, political and economic contexts from which these medical technologies emerged, and, in turn, how technical innovations gave rise to new social constellations. A central purpose of the volume is to show what consequences new practices linked to the uptake of certain technologies had for the history of medicine more widely.