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This text focuses on various factors associated with orphan diseases and the influence and role of health information technologies. Orphan diseases have not been adopted by the pharmaceutical industry because they provide little financial incentive to treat or prevent it. It is estimated that 6,000-7,000 orphan diseases exist today; as medical knowledge continues to expand, this number is likely to become much greater. The book highlights the opportunities and challenges in this increasingly important area. The book explores new avenues which are opened by information technologies and Health 2.0, and highlights also economic opportunities of orphan disease medicine. The editors of this new book have international experience and competencies in the key areas of patient empowerment, healthcare and clinical knowledge management, healthcare inequalities and disparities, rare diseases and patient advocacy.
Despite the evolution and growing awareness of patient safety, many medical professionals are not a part of this important conversation. Clinicians often believe they are too busy taking care of patients to adopt and implement patient safety initiatives and that acknowledging medical errors is an affront to their skills.
"Patient Safety" provides clinicians with a better understanding of the prevalence, causes and solutions for medical errors; bringing best practice principles to the bedside. Written by experts from a variety of backgrounds, each chapter features an analysis of clinical cases based on the Root Cause Analysis (RCA) methodology, along with case-based discussions on various patient safety topics. The systems and processes outlined in the book are general and broadly applicable to institutions of all sizes and structures.
The core ethic of medical professionals is to do no harm . "Patient Safety" is a comprehensive resource for physicians, nurses and students, as well as healthcare leaders and administrators for identifying, solving and preventing medical error.
Bernhard Gleich introduces Magnetic Particle Imaging (MPI) including all aspects that are necessary for a complete understanding. MPI is a new imaging modality invented by Bernhard Gleich and Jurgen Weizenecker. The method is capable of imaging the distribution of superparamagnetic iron oxide particles (SPIOs) with high sensitivity, high spatial resolution, and high imaging speed. The author summarizes the results of a number of original papers and countless innovations he has elaborated in the young discipline of magnetic particle imaging."
This book strips away the misconceptions about medical care for
arthritis and reveals a safer and more effective treatment.
Swamy Laxminarayan was an outstanding researcher active in many diverse fields of science and technology. This liber amicorum in memory of Swamy Laxminarayan collects Medical and Biological Engineering and Informatics contributions to the Safety and Security of Individuals and Society. The authors are renowned scientists and the aim of their writing is to recall the enormous personal and scientific achievement of Swamy Laxminarayan.
This book describes the state of the art on computational modeling and fabrication in Tissue Engineering. It is inspired by the ECCOMAS thematic conference, the European Committee on Computational Methods in Applied Sciences, on Tissue Engineering, held in Lisbon, Portugal, June 2-4, 2011. Tissue Engineering is a multidisciplinary field involving scientists from different fields. The development of mathematical methods is quite relevant to understand cell biology and human tissues as well to model, design and fabricate optimized and smart scaffolds. Emphasis is put on mathematical and computational modeling for scaffold design and fabrication. This particular area of tissue engineering, whose goal is to obtain substitutes for hard tissues such as bone and cartilage, is growing in importance.
"Best help with evidence-based medicine available." Marty Gabica MD, Chief Medical Officer, Healthwise
"I am full of admiration for this terrific little book...which is written clearly, simply and appropriately for a starter audience. Those with more experience...can benefit too. I know of no other book that has succeeded so well in getting everything important covered so succinctly, which the authors have done brilliantly well " Richard Lehman, MA, BM, BCh, Oxford, & Blogger, BMJ Journal Watch
The shocking truth is that most scientific research that informs most doctors' medical decisions is unreliable or is of uncertain reliability. And many doctors and other health care professionals do not realize this. Every day patients are harmed by unfortunate health care choices-and some of them die because of it. Too often this happens because of problems with the information provided to the patient-or its lack-where different information could have resulted in a very different choice-and a very different outcome.
The good news is that you only need to know a few, easy-to-understand statistics, and you need a few basic concepts to help you understand bias and chance.
Medical evidologists and clinical improvement experts, Sheri Ann Strite and Michael E. Stuart MD, provide you with easy-to-understand guidance.
In a few hours, you can learn basic critical appraisal skills to help you evaluate clinical trials and other medical research studies of therapeutic interventions.
Based on their popular simplified and tool-based approach, the authors show you how to evaluate the reliability and clinical usefulness of clinical trials. Written for physicians and other health care professionals, this book is written in easy-to-understand terms that even the layperson can understand and put to use.
What is Unique About This Book
Practical-information can be applied instantly Concise-can be read in a few hours
Clear-key concepts are explained in easy-to-understand language
Complete enough-We give you the basics you need to evaluate most clinical trials of therapies. We don't bog you down with details you do not need to know. With rare exception, or unless you are a researcher, you don't need to know such concepts as the different observational study types, you don't need to understand power calculations, and you only need a few, easy-to-understand statistics-we give you simple explanations that you can even use in explaining results to patients.
You will learn that the primary key to understanding the reliability of studies is largely about study design, execution and study performance outcomes. You will learn-
-Experiments versus Observations: The quick and easy way to distinguish between experiments and observations-and why you need to know the difference.
-Assessing Selection Bias: 5 Essential Questions Important considerations include who was studied, how were they selected for study, are there enough people, how were they assigned to their study groups, and are the groups balanced?
-Assessing Performance Bias: 2 Essential Questions What is being studied, and what is it being compared to? What else happened to study subjects in the course of the study?
-Assessing Measurement & Attrition Bias: 2 Essential Questions What information was collected, and how was it collected? What data are missing, and does missing data meaningfully distort the study results?
-Assessing Assessment Bias: 2 Essential Questions How is the difference in outcomes between the groups evaluated? What are those differences and how are they expressed?
-Easy Ways to Evaluate Results
-Evaluating Authors' Conclusions
This book will help your patients better avoid what has happened to millions of patients-insufficient or misleading information leading to unfortunate choices that resulted in bad outcomes.
Almost everyone suffers from back pain and neck pain at some point in life. In an effort to find relief, people turn to a wide variety of treatments, and to doctors who will prescribe medications such as painkillers and muscle relaxers. What they don't realize is that many of these treatments -- especially some medications -- actually interfere with the body's own ability to heal and overcome pain. When these treatments fail to help, they desperately conclude that surgery is their only option for relief. They often think their condition is worse than it is and that they have no hope for relief; when if fact quite the opposite is the case. In award winning book, Conquer Back and Neck Pain, renowned spine specialist, Dr. Mark Brown, explains exactly what causes back pain and why humans are so predisposed to spinal problems. He provides a detailed questionnaire that allows you to identify which of seven most common types of back pain you are experiencing, and then he explains each of those types in clear and easy-to-understand language. In his 40 years of experience, he has found that the vast majority of back pain cases will resolve with minimal treatment. In fact, the very best thing you can do is to simply allow your body to heal itself by avoiding the many treatment pitfalls that people with back pain commonly fall into when looking for relief. Avoiding these mistakes, along with incorporating low impact, aerobic exercise, will almost always allow you to walk off your back or neck pain naturally. With an interesting collection of anecdotes and a frank discussion of the pitfalls that come with many of the back-pain treatments out there, Conquer Back and Neck Pain will give you fresh, new insight into how your back really works and how to finally find healthy relief from your back pain.
The international symposium CAR '89 (the third in a row), held in Berlin in June 1989, was again focused on the fundamental principles of applying Computer Assisted Radiology (CAR) in health care. The book contains all the presentations of the symposium and this provides an up-to-date, complete state-of-the-art-report of this interdisciplinary subject, in which physicians, engineers, physicists and computer scientists cooperate.
Dr. Tavel, a physician and internist/cardiologist, has managed patients for many years. He has generated more than one hundred research studies which have appeared in a variety of the major peer-reviewed medical journals and has participated on the editorial boards of several of them. He is the author of an internationally recognized book on cardiovascular disease and has contributed to numerous other medical books. Holding a faculty position (clinical professor) at Indiana University School of Medicine, he regularly instructs medical trainees at all levels. Because of the many misconceptions he has encountered from both laymen and many of those involved in medical care, Dr. Tavel has now turned his attention to the general public. In this hard-hitting book, he attacks misinformation covering health matters of all types. Snake oil is a term metaphorically applied to the many methods of treatment that lack scientific credibility, including quackery of all types, alternative medicine, procedures such as acupuncture and chiropractic medicine, misinformation about diets, vitamins, and other dietary supplementation, antioxidants, and many others. His thoughts also extend to the less-obvious myths surrounding such diverse topics as the tricks performed by the so-called ethical pharmaceutical companies, and the illusion surrounding the apparent success of all types of medical management-both conventional and outlandish-much of which can be explained by the so-called placebo effect. Understanding these myths can pave the way toward healthier living and better medical care, while at the same time, reducing personal expenses. In the process of dispelling myths, Dr. Tavel presents a detailed analysis of how biases and myths are formed, which, in itself, can lead the individual toward better self-awareness and more profound understanding of many issues beyond health. These include such diverse subjects as why the self-proclaimed experts are usually wrong about the stock market, odds at sporting events and casinos, and even why our political leaders are so often prone to false conclusions. Dr. Tavel's insights provide useful information to everyone-especially to those giving or receiving care and advice about matters of health. .
-Rick Thomas brings his 30 years experience in the field to the text making it very applied and accessible. -Lots of boxed material. -"Recommended" purchase for all librarians as reviewed in the June 2004 issue of CHOICE.
Tissue engineering and regenerative medicine uses a combination of cells, scaffolding and bioreactive factors to treat a variety of pathological conditions and has become a treatment option for many adult diseases. In this book, the authors present current research from across the globe, in the study of the fundamentals, techniques and applications of tissue engineering. Topics discussed in this compilation include the characterization of liver organogenesis and foetal and adult stem/progenitor cells; in vitro biological activity of double and triple component system scaffolds in bone tissue engineering; stretching bioreactors for dynamic engineering of muscle tissues; adipose-derived stem cells and their application in tissue engineering; regenerative medicine and tissue engineering for congenital birth defects.
CAR is a symposium and exhibition covering the impact of computer and communication systems applied to radiology and other medical disciplines, which use digital imaging for diagnosis and therapy planning. CAR '93 also provides tutorials, but more emphasis is given to a broad variety of specific problems related to medical/technical issues in digital imaging. This is achieved through in-depth presentations of results of current medical imaging projects on a worldwide basis.
Previously published as Strategic Information Management in Hospitals; An Introduction to Hospital Information Systems, Health Information Systems Architectures and Strategies is a definitive volume written by four authoritative voices in medical informatics. Illustrating the importance of hospital information management in delivering high quality health care at the lowest possible cost, this book provides the essential resources needed by the medical informatics specialist to understand and successfully manage the complex nature of hospital information systems. Author of the first edition's Foreword, Reed M. Gardner, PhD, Professor and Chair, Department of Medical Informatics, University of Utah and LDS Hospital, Salt Lake City, Utah, applauded the text's focus on the underlying administrative systems that are in place in hospitals throughout the world. He wrote, "These challenging systems that acquire, process and manage the patient's clinical information. Hospital information systems provide a major part of the information needed by those paying for health care." their components; health information systems; architectures of hospital information systems; and organizational structures for information management.
This volume contains the proceedings of the NATO Advanced Study Institute on "Pictorial Information Systems in Medicine" held August 27-September 7, 1984 in Hotel Maritim, Braunlage/Harz, Federal Republic of Germany. The program committee of the institute consisted of KH Hohne (Director), G. T Herman, G. S. Lodwick, and D. Meyer-Ebrecht. The organization was in the hands of Klaus Assmann and Fritz Bocker In the last decade medical imaging has undergone a rapid development New imaging modalities such as Computer Tomography (CT), Digital Angiography (DSA) and Magnetic Resonance Imaging (MRI) were developed using the capabilities of modern computers. In a modern hospital these technologies produce already more then 25% of image data in digital form. This format lends itself to the design of computer assisted Information systems Integrating data acquisition, presentation, communi cation and archiving for all modalities and users within a department or even a hospital. Advantages such as rapid access to any archived Image, synoptic presentation, computer assisted image analysis to name only a few, are expected. The design of such pictorial information systems, however, often called PACS (Picture Archiving and Communication Systems) In the medical community is a non-trivial task involving know-how from many disciplines such as - Medicine (especially Radiology), - Data Base Technology, - Computer Graphics, - Man Machine Interaction, - Hardware Technology and others. Most of these disCiplines are represented by disjunct scientific communities."
This is a textbook for health professionals on the topic of tobacco reduction and cessation.
This textbook is a scientific introduction to the study, engineering and applications of medical textiles. It moves systematically from the fundamentals of textile materials and their fabrication through biocompatibility and biodegradability to the applications of textiles in healthcare, ranging from hygiene to wound care, grafts and implantables. The book analyzes how the internal structures of various types of textiles, wovens, knits and nonwovens, are related to specific medical/biomedical end uses. While carefully explaining the basics, the book aims to show the connection between textile properties and the design and development of medical and healthcare textile products. This text is designed for advanced students and industry-based textile researchers, engineers, and product developers.
are then selected and must meet the general 'biocompatibility' require- ments. Prototypes are built and tested to include biocompatibility evalua- tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.
Despite all the jokes about the poor quality of physician handwriting, physician adoption of computerized provider order entry (CPOE) in hospitals still lags behind other industries' use of technology. As of the end of 2010, less than 22% of hospitals had deployed CPOE. Yet experts claim that this technology reduces over 80% of medication errors and could prevent an estimated 522,000 serious medication errors annually in the US. Even though the federal government has offered $20 billion dollars in incentives to hospitals and health systems through the 2009 stimulus (the ARRA HITECH section of the American Recovery and Reinvestment Act of 2009), many organizations are struggling to implement advanced clinical information systems including CPOE. In addition, industry experts estimate that the healthcare industry is lacking as many as 40,000 persons with expertise in clinical informatics necessary to make it all happen by the 2016 deadline for these incentives. While the scientific literature contains numerous studies and stories about CPOE, no one has written a comprehensive, practical guide like Making CPOE Work. While early adopters of CPOE were mainly academic hospitals, community hospitals are now proceeding with CPOE projects and need a comprehensive guide. Making CPOE Work is a book that will provide a concise guide to help both new and experienced health informatics teams successfully plan and implement CPOE. The book, in a narrative style, draws on the author's decade-long experiences of implementing CPOE at a variety of academic, pediatric and community hospitals across the United States.
This book constitutes the refereed proceedings of the 7th International Conference on Pattern Recognition in Bioinformatics, PRIB 2012, held in Tokyo, Japan, in November 2012. The 24 revised full papers presented were carefully reviewed and selected from 33 submissions. Their topics are widely ranging from fundamental techniques, sequence analysis to biological network analysis. The papers are organized in topical sections on generic methods, visualization, image analysis, and platforms, applications of pattern recognition techniques, protein structure and docking, complex data analysis, and sequence analysis.
The pervasive healthcare system focus towards achieving two specific goals: the availability of eHealth applications and medical information anywhere and anytime and the invisibility of computing. Furthermore, pervasive health system encompasses new types of sensing and communication of health information as well as new type of interactions among health providers and people, among patients, among patients and researchers and patients and corporations. This book aims at promoting the discussion on current trends in technologies and concepts that help integrate health monitoring and healthcare more seamlessly to our everyday lives, regardless of space and time, but also present cutting edge perspectives and visions to highlight future development. The book presents not only the state of the art technologies and solutions to tackle the critical challenges faced by the building and development of the pervasive health system but also potential impact on society at social, medical and technological level.
Virtual Reality has the potential to provide descriptive and practical information for medical training and therapy while relieving the patient or the physician. Multimodal interactions between the user and the virtual environment facilitate the generation of high-fidelity sensory impressions, by using not only visual and auditory, but also kinesthetic, tactile, and even olfactory feedback modalities. On the basis of the existing physiological constraints, Virtual Reality in Medicine derives the technical requirements and design principles of multimodal input devices, displays, and rendering techniques. Resulting from a course taught by the authors, Virtual Reality in Medicine presents examples for surgical training, intra-operative augmentation, and rehabilitation that are already in use as well as those currently in development. It is well suited as introductory material for engineering and computer science students, as well as researchers who want to learn more about basic technologies in the area of virtual reality applied to medicine. It also provides a broad overview to non-engineering students as well as clinical users, who desire to learn more about the current state of the art and future applications of this technology.
Roger M. Nocera, M.D., a world leader in stem cell therapy research, announces a breakthrough medical science discovery that will revolutionize health care as we know it. In his new book "Cells That Heal Us From Cradle To Grave: A Quantum Leap in Medical Science," Dr. Nocera reveals that a medical science discovery made in 2003 has been developed in medical clinics around the world and proven to be effective in the treatment of many heretofore incurable diseases. Cells That Heal Us From Cradle To Grave explains how this medical science discovery is on a par with Immunology discovered two centuries ago with the smallpox vaccine, and with the discovery of antibiotics a century later. Dr. Nocera's book is a primer on how this amazing new medical technology will completely nullify our current medical health care and pharmaceutical research systems. Cells That Heal Us From Cradle To Grave explains that there is a class of stem cells that are naturally created by the human body which heal every disease and injury that attack our bodies. These Healing Cells are naturally present in every body, and are fully transplantable from one person to another without any threat of rejection. Treatments with Healing Cells is as simple as receiving an injection, and the cells are naturally found in stored body fat or umbilical cord medical "waste." Healing Cells are NOT embryonic stem cells, which have turned out to be the very worst possible choice for stem cell research. To date, hundreds of patients have been successfully treated in offshore clinics - offshore due to an FDA moratorium on stem cell treatments in the U.S. In this book Dr. Nocera calls for a lift of this ban to make this phenomenal medical science available to all Americans who suffer with numerous diseases and conditions that can now be successfully treated with Healing Cells. Although Americans spend 18% of our GDP on health care, over twice that of most Western countries, we are ranked 72nd in overall health of our citizens by the World Health Organization. As this Healing Cell Quantum Leap in Medical Science becomes widely available Dr. Nocera predicts that the ever rising costs of medical care in this country will diminish significantly and treatments will often actually cure the underlying diseases rather than merely mask the symptoms. Partial list of diseases and conditions successfully treated with Healing Cells: multiple sclerosis, rheumatoid arthritis, type 2 diabetes mellitus, autism, muscular dystrophy, cerebral palsy and spinal cord injury.
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