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Books > Medicine > General issues > Medical equipment & techniques > General
This is a meticulously detailed chronological record of significant
events in the history of medical informatics and their impact on
direct patient care and clinical research, offering a
representative sampling of published contributions to the field.
The History of Medical Informatics in the United States has been
restructured within this new edition, reflecting the transformation
medical informatics has undergone in the years since 1990. The
systems that were once exclusively institutionally driven -
hospital, multihospital, and outpatient information systems - are
today joined by systems that are driven by clinical subspecialties,
nursing, pathology, clinical laboratory, pharmacy, imaging, and
more. At the core is the person - not the clinician, not the
institution - whose health all these systems are designed to serve.
A group of world-renowned authors have joined forces with Dr Marion
Ball to bring Dr Collen's incredible work to press. These
recognized leaders in medical informatics, many of whom are
recipients of the Morris F. Collen Award in Medical Informatics and
were friends of or mentored by Dr Collen, carefully reviewed,
editing and updating his draft chapters. This has resulted in the
most thorough history of the subject imaginable, and also provides
readers with a roadmap for the subject well into later in the
century.
The NATO Advanced Study Institute "Biomedical Optical
Instrumentation and Laser Assisted Biotechnology" was held November
10-22, 1995 in Erice, Sicily. This was the 19 th conference
organized by the International School of Quantum Electronics, under
the auspices of the "Ettore Majorana" Center for Scientific
Culture. The contributions presented at the Institute are written
as extended, review-like papers to provide a broad and
representative coverage of the fields of laser techniques,
optoelectronics systems for medical diagnosis, and light and laser
applications to Biology and Medicine. The aim of the Institute was
to bring together some of the world's acknowledged scientists and
clinicians that belong to different disciplines and consequently do
not usually meet, but who have as a common link the use of
optoelectronics instrumentation, techniques and procedures. Most of
the lecturers attended all the lectures and devoted their spare
hours to stimulating discussions. We would like to thank them all
for their admirable contributions. The Institute also took
advantage of a very active audience; most of the participants were
active researchers in the field and contributed with discussions
and seminars. Some of these seminars are also included in these
Proceedings. The Institute was an important opportunity to discuss
latest developments and emerging perspectives on the use of laser
sources and optoelectronic techniques for diagnostic and
therapeutic purposes."
The Microsystems Series has as its goal the creation of an
outstanding set of textbooks, references, and monographs on
subjects that span the broad field of microsystems. Exceptional PhD
dissertations provide a good starting point for such a series,
because, unlike monographs by more senior authors, which must
compete with other professional duties for attention, the
dissertation becomes the sole focus of the author until it is
completed. Conversion to book form is then a streamlined process,
with final editing and book production completed within a few
months. Thus we are able to bring important and timely material
into book form at a pace which tracks this rapidly developing
field. Our first four books in the series were drawn from the more
physics-oriented side of the microsystems field, including such
diverse subjects as computer-aided design, atomic-force microscopy,
and ultrasonic motion detection. Now, with Sangeeta Bhatia's work,
we enter the realm of biology. Her use of artifically structured
substrates to encourage the liver cells to form orderly assemblies
is a fine example of how microfabrication technology can contribute
to cell biology and medicine. I am pleased to be able to add this
very new and very interesting work to the Microsystems Series.
Stephen D. Senturia Cambridge MA Microfabrication in Tissue
Engineering and Bioartificial Organs Foreword One of the emerging
applications of microsystems technology in biology and medicine is
in the field of tissue engineering and artificial organs. In order
to function, cells need to receive proper signals from their
environment.
The medical device and drug industries standards in analytical
methodology and are consistently among the strongest techno-
quality control. logical performers. Materials are a key The users
of Biomaterials Engineering ingredient in their dynamic growth.
Devel- and Devices: Human Applications will r- opment of these
materials is in a constant resent a broad base of backgrounds
ranging state of activity, with the challenge of re- from the basic
sciences (e. g. , polymer placing old materials that cannot
withstand chemistry and biochemistry) to more the tests of time,
and the new materials' applied disciplines (e. g. , mechanical/
needs coming to the forefront in modern chemical engineering,
orthopedics, and applications. This new reference text,
pharmaceutics). To meet varied needs, each Biomaterials Engineering
and Devices: chapter provides clear ancd fully detailed Human
Applications, focuses on materials discussions. This in-depth, but
practical, used in or on the human body-materials coverage should
also assist recent indu- that define the world of "biomaterials. "
ees to the biomaterials circle. The editors Biomaterials
Engineering and Devices: trust that this reference textbook conveys
Human Applications focuses on mate- the intensity of this fast
moving field in an rials development and characterization.
enthusastic presentation. Chapters deal with issues in the
selection of Donald L. Wise, PHD proper biomaterials from
biocompatibility Debra J. Trantolo, PHD to biostability to
structure/function relation- Kai-Uwe Lewandrowski, MD ships.
Chapters also focus on the use of Joseph D. Gresser, PHD specific
biomaterials based on their physio- Mario V.
"After decades of research on dysfunctional eating and lack of
physical activity, research attention has finally turned to the
role of digital technology in eating behaviors and eating
disorders. This timely volume offers a thoughtful and wide
collection of chapters discussing the possible effects of digital
technologies, from those enhancing healthy eating behaviors to
those that encourage disordered eating. Highly recommended for both
professionals and scholars." Prof. Giuseppe Riva, Universita
Cattolica del Sacro Cuore, Milan, Italy. This book examines in
depth the multifaceted roles of digital technologies in the eating
behaviors and eating disorders. Coverage reflects a broad
theoretical and empirical knowledge of current trends in digital
technology use in health behaviors, and their risks and benefits
affecting wellbeing, with focus on eating behaviors and eating
disorders. The authors use both qualitative and quantitative data
to focus on the digital lived experiences of people and their
eating related behaviors. Among the topics covered: The quality of
eating-oriented information online Technology, body image, and
disordered eating Eating-oriented online groups Using mobile
technology in eating behaviors Usage of digital technology among
people with eating disorders What healthcare professionals should
know about digital technologies and eating disorders
Technology-based prevention and treatment programs for eating
disorders A potential source of discussion and debate in various
fields across the social sciences, the health sciences, and
psychology, Digital Technology, Eating Behaviors, and Eating
Disorders will be especially useful to students, academics,
researchers, and professionals working in the fields of eating
behaviors and eating disorders.
The goal of tissue engineering is to repair or replace tissues and organs by delivering implanted cells, scaffolds, DNA, proteins, and/or protein fragments at surgery. Tissue engineering merges aspects of engineering and biology, and many rapid achievements in this field have arisen in part from significant advances in cell and molecular biology. Functional Tissue Engineering addresses the key issues in repairing and replacing load-bearing structures effectively. What are the thresholds of force, stress, and strain that normal tissues transmit or encounter? What are the mechanical properties of these tissues when subjected to expected in vivo stresses and strains, as well as under failure conditions? Do tissue engineered repairs and replacements need to exactly duplicate the structure and function of the normal tissue or organ? When developing these implants in culture, how do physical factors such as mechanical stress regulate cell behavior in bioreactors as compared to signals experienced in vivo? And finally, can tissue engineers mechanically stimulate these implants before surgery to produce a better repair outcome? Chapters written by well-known researchers discuss these matters and provide guidelines and a summary of the current state of technology. Functional Tissue Engineering will be useful to students and researchers as it will remind tissue engineers of the clinical importance of restoring function to damaged tissue and structures. Further, the book clarifies the identification of critical structural and mechanical requirements needed for each construct. Functional Tissue Engineering also provides an invaluable resource to help tissue engineers incorporate these functional criteria into the design, manufacture, and optimization of tissue engineered products. Finally it serves as a reference and teaching text for the rapidly increasing population of students and investigators in the field of tissue engineering.
Bioinformatics and Drug Discovery describes the bioinformatic
approaches and techniques employed along the pipeline of drug
development from genes to proteins to drugs. The book focuses on
gene microarray analysis and techniques for target identification
and validation. In addition, clinical applications showing how the
analysis can be used for prognostication and diagnosis are
described. The second section focuses on protein analysis,
including target validation and identification using modern
proteomic analysis as well as protein modeling techniques. The
third section discusses chemoinformatics, including virtual
screening and how to computationally approach chemical space.
In the last two centuries, medicine has been transformed by a
number of major technological and organisational innovations. This
edited collection examines the role of medical technologies in the
history of medicine, of new diagnostic and therapeutic tools,
prostheses and apparatus. The volume also discusses the social,
cultural, political and economic contexts from which these medical
technologies emerged, and, in turn, how technical innovations gave
rise to new social constellations. A central purpose of the volume
is to show what consequences new practices linked to the uptake of
certain technologies had for the history of medicine more widely.
This monograph explores Intrabody communication (IBC) as a novel
non-RF wireless data communication technique using the human body
itself as the communication channel or transmission medium. In
particular, the book investigates Intrabody Communication
considering limb joint effects within the transmission frequency
range 0.3-200 MHz. Based on in-vivo experiments which determine the
effects of size, situations, and locations of joints on the IBC,
the book proposes a new IBC circuit model explaining elbow joint
effects. This model not only takes the limb joint effects of the
body into account but also considers the influence of measurement
equipment in higher frequency band thus predicting signal
attenuation behavior over wider frequency ranges. Finally, this
work proposes transmitter and receiver architectures for intrabody
communication. A carrier-free scheme based on impulse radio for the
IBC is implemented on a FPGA.
This volume covers some of the topics that are related to the
rapidly growing field of biomedical informatics. In June 11-12,
2010 a workshop entitled 'Optimization and Data Analysis in
Biomedical Informatics' was organized at The Fields Institute.
Following this event invited contributions were gathered based on
the talks presented at the workshop, and additional invited
chapters were chosen from world's leading experts. In this
publication, the authors share their expertise in the form of
state-of-the-art research and review chapters, bringing together
researchers from different disciplines and emphasizing the value of
mathematical methods in the areas of clinical sciences. This work
is targeted to applied mathematicians, computer scientists,
industrial engineers, and clinical scientists who are interested in
exploring emerging and fascinating interdisciplinary topics of
research. It is designed to further stimulate and enhance fruitful
collaborations between scientists from different disciplines.
Within the various aspects of life-science technologies medicine
and information technology will change next millennium's
quality-of-life fundamentally. Thanks to the rapid growth of
telecommunication industry and the success and popularity of the
internet the face of medicine will essentially change, because
information technology is expected to play a major role in future
health care systems. The conference MEDICOM 2000 is a discussion
forum on fast and cost efficient patient-data exchange systems
between doctors' offices, medical laboratories, telearchive
services, health care insurances, highly specialized experts in
hospitals etc. The conference brought together scientific, medical
and application experts from university, clinical and commercial
sites of both areas - medicine and communication - to stimulate
synergy between these rapidly evolving future technologies. We
would like to acknowledge all the parties who contributed to the
success of the conference. Especially, we would like to thank
Gisela Niedzwetzki and Waltraud Ott for secretarial support as well
as Dirk Thomsen for web mastering. Additionally, we have to
acknowledge the valuable support of Holger Dorle, Thomas Giese,
Peter Just, Stefan Klockner, Heike Lahr and Kerstin Ltidtke-Buzug
during the conference.
This book describes more than 60 web-accessible computational tools
for protein analysis and is totally practical, with detailed
explanations on how to use these tools and interpret their results
and minimal mentions to their theoretical basis (only when that is
required for making a better use of them). It covers a wide range
of tools for dealing with different aspects of proteins, from their
sequences, to their three-dimensional structures, and the
biological networks they are immersed in. The selection of tools is
based on the experience of the authors that lead a protein
bioinformatics facility in a large research centre, with the
additional constraint that the tools should be accessible through
standard web browsers without requiring the local installation of
specific software, command-line tools, etc. The web tools covered
include those aimed to retrieve protein information, look for
similar proteins, generate pair-wise and multiple sequence
alignments of protein sequences, work with protein domains and
motifs, study the phylogeny of a family of proteins, retrieve,
manipulate and visualize protein three-dimensional structures,
predict protein structural features as well as whole
three-dimensional structures, extract biological information from
protein structures, summarize large protein sets, study protein
interaction and metabolic networks, etc. The book is associated to
a dynamic web site that will reflect changes in the web addresses
of the tools, updates of these, etc. It also contains QR codes that
can be scanned with any device to direct its browser to the tool
web site. This monograph will be most valuable for researchers in
experimental labs without specific knowledge on bioinformatics or
computing.
In this book, leading authors in the field discuss the habitats of
tomorrow. These habitats will be connected through autonomous and
assistive systems, turning habitats into health resorts. This book
discusses how assistance technologies enable a smooth transition
from comfortable health support to medical or nursing care. The
contributions have been chosen and invited at the 9th AAL congress,
Frankfurt.
This volume is a result of the fruitful and vivid discussions
during the MedDecSup'2012 International Workshop bringing together
a relevant body of knowledge, and new developments in the
increasingly important field of medical informatics. This carefully
edited book presents new ideas aimed at the development of
intelligent processing of various kinds of medical information and
the perfection of the contemporary computer systems for medical
decision support. The book presents advances of the medical
information systems for intelligent archiving, processing, analysis
and search-by-content which will improve the quality of the medical
services for every patient and of the global healthcare system. The
book combines in a synergistic way theoretical developments with
the practicability of the approaches developed and presents the
last developments and achievements in medical informatics to a
broad range of readers: engineers, mathematicians, physicians, and
PhD students.
The health care delivery system, its organizations, and its
supporting industries are currently undergoing immense changes and
at the center of this change is technology. This book is about the
management of this technology. The authors refer to this new
intellectual space as the Management of Medical Technology (MMT).
From the core activities of delivering medical care, to the
supporting industries producing technical systems, pharmaceuticals,
medical devices, information technology, and finally to the
insurers of health care - all of these demonstrate the central role
technology plays in delivering health. Management of Medical
Technology examines the many aspects of managing medical
technology, discusses its key issues, and outlines how it can be
managed more effectively. This is a foundational book in Kluwer's
Series on MMT. It is designed for academics and students in all
areas of management related to health care, as a text for related
undergraduate and graduate courses, as well as a reference book for
health care executives and managers of technology in industry. The
book is divided into three complementary parts. Part 1 explores the
theory of MMT and in six chapters outlines the new intellectual
space of MMT and its theoretical background. Part 2 is dedicated to
the practice of MMT. This part has six chapters and describes the
two main empirical studies conducted by the authors on MMT; one
study examined how hospitals currently manage medical technology
and the second study investigated the management of medical
information technology. Moreover, related to the practice of MMT,
this part also discusses in detail issues of effectiveness of
delivery, patient value and patientwelfare, and education in MMT.
Part 3 is a thorough treatment of MMT cases in a variety of health
care organizations, each describing a different phenomenon in the
practice of MMT. Eleven cases are included, with discussion
questions for use in the classroom.
Recent years have seen the development of two significant trends
namely: the adoption of some Traditional Chinese Medicine Practices
into mainstream Allopathic Western Medicine and the advent of the
internet and broad band networks leading to an increased interest
in the use of Telemedicine to deliver medical services. In this
book, we see the convergence of these two trends leading to a
semantically-based TCM Telemedicine system that utilizes an
ontology to provide sharable knowledge in the TCM realm to achieve
this. The underpinning research required the development of a
three-layer architecture and an Ontology of the TCM knowledge. As
TCM knowledge like all medical knowledge is not frozen in time it
was important to develop an approach that would allow evolution of
the Ontology when new evidence became available. In order for the
system to be practically grounded it was important to work with an
industry partner PuraPharm Group/HerbMiners Informatics Limited.
This partnership was initiated through Professor Allan Wong and the
Chairman of PuraPharm Group Mr. Abraham Chan. This led to the
system being utilized in more than 20 Mobile Clinics in Hong Kong
and 300 Hospitals in China. In order for these different
deployments of the system to be coherent with the main core
Ontology, it was necessary for us to develop an Ontology Driven
Software System Generation approach.
Evaluation Methods in Medical Informatics, Second Edition is a
heavily updated and revised volume based on editors Friedman and
Wyatt's successful first edition. This book incorporates the solid
foundation of evaluation theories, methods, and techniques laid out
in the first edition, and builds on it to include case studies from
real world situations. Designed as a guide for both the informatics
novice and the seasoned professional seeking a comprehensive
resource, this book explores information systems evaluation from
the ground up. Critique and disscussion of actual evaluation
efforts will guide the reader through real world application of the
techniques described.
Just like its first edition, this volume is an unparalled
reference for a broad range of health information professionals.
From those in training for careers in informatics to on-site
medical information systems staff, Evaluation Methods in Medical
Informatics, Second Edition is an invaluable guide to successful
evaluation of information technology in health care.
The present book entitled "Novel Frontiers in the Production of
Compounds for Biomedical Uses" can perhaps be placed in its best
perspective by the Shakespearean character in The Tempest who
exclaimed" What's past is prologue." Indeed, this compilation of
some of the outstanding presentations in the field of biomedicine
made at th the 9 European Congress on Biotechnology (Brussels,
Belgium, July 11-15, 1999) not only reflects the achievements of
the recent past, but provides a privileged glimpse of the
biotechnology that is emerging in the first decade of the new
Millennium. It is becoming increasingly apparent that biotechnology
is offering biomedicine novel approaches and solutions to develop a
sorely needed new generation of biopharmaceuticals. This is all the
more necessary because in recent years, new diseases have emerged
with extraordinary lethality in all corners of the globe, while
age-related chronic illnesses have filled the gap wherever
biomedicine has made successful inroads. The rise of antibiotic
resistance also poses major threats to public health. Thus, as
disease patterns evolve, the rational development of new drugs is
becoming urgent, not only for the clinical outcome of patients, but
also in optimising the allocation of scarce health care resources
through the use of cost-effective productions methods. It is in
response to all these challenges that biotechnology offers new
strategies that go beyond the more traditional approaches. By the
mid-1990's, the number of recombinant products approved annually
for therapeutic use reached double digits. With the advent of the
genomics revolution.
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