This comprehensive volume spotlights the latest research into how and why the much-maligned and misunderstood Vitamin D is finally coming into its own, and how to gain the greatest benefits from it. Vitamin D keeps a range of chronic and life-threatening diseases at bay.

A fascinating exploration of the skin in its multifaceted physical, psychological, and social aspects Providing a cover for our delicate and intricate bodies, the skin is our largest and fastest-growing organ. We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

Selected as a Doody's Core Title for 2022! Lippincott (R) Connect Featured Title Purchase the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Reflecting the trusted expertise of Dr. John B. West and Dr. Andrew M. Luks, West's Pulmonary Pathophysiology: The Essentials, Tenth Edition offers accessible explanations of disease processes that affect the respiratory system. This best-selling companion to West's Respiratory Physiology: The Essentials, 11th Edition, has served generations of students and practitioners who work with respiratory patients, presenting vital knowledge in a concise, straightforward manner that's easy to understand. Building on this legacy of success, the tenth edition is updated throughout with the latest clinical perspectives, new images, clinical vignettes, and enhanced USMLE-style review questions to help students excel in today's changing healthcare practice. UPDATED! Clinical Vignettes with open-ended questions demonstrate the real-world application of basic science and strengthen students' self-assessment. UPDATED! Radiographs, CT images, and color histopathologic sections clarify diagnostic and therapeutic approaches. UPDATED! USMLE-style multiple-choice questions, with answers, at the end of each chapter reveal areas requiring further study and boost students' test-taking confidence. Clinical features/notes boxes provide efficient, bulleted review for key diseases. End-of-chapter Key Concepts reviews reinforce essential chapter information at a glance. Appendices provide fast access to symbols, units, and normal values; further readings; and answers to multiple-choice and Clinical Vignette questions. Online video lectures, available via YouTube, engage students in the material and clarify challenging textbook concepts. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

Clinics in Developmental Medicine No. 160

Children with craniosynostosis are born with congenital deformities of the face and skull. In severe cases associated problems are common. The child who is not properly cared for can end up blind, deaf and with severe learning difficulties. In addition, they may be left with unacceptable facial deformities. Outside specialized craniofacial units, there is at present nowhere for those involved in primary or secondary care to go for help with the many practical problems that these children present. In this book, a distinguished team of editors have assembled experts in the field to introduce the non-craniofacial specialist to what can be achieved and how they can contribute to the child's welfare. It will be essential reading for paediatricians seeking practical information about the management of these disorders, and for specialists in neurosurgery, ENT, ophthalmology, plastic surgery, maxillo-facial surgery, orthodontics, psychology, genetics, anaesthesia, audiology and speech therapy.

Selected as a Doody's Core Title for 2021! Lippincott (R) Connect Featured Title Purchase the new print edition of this Lippincott (R) Connect title includes lifetime access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. For more than 40 years, West's Respiratory Physiology: The Essentials has remained a critical resource for medical and allied health students learning the basics of respiratory physiology as well as an effective, quick review for residents and fellows in pulmonary medicine, critical care, anesthesiology, and internal medicine as they prepare for licensing and other exams. The eleventh edition incorporates updates in many areas including blood-tissue gas exchange, mechanics, control of ventilation and the respiratory system under stress; all designed to aid clear understanding of pulmonary physiology. Clinical vignettes with questions emphasize how the physiology described can be applied to clinical situations, reinforcing reasoning and critical thinking. More than 100 USMLE-style multiple-choice questions with full explanations test reasoning skills for comprehension and exam preparation. Additional learning objectives and chapter-opening content added to every chapter to improve understanding of key topics. Appendices include important equations, answers to the multiple-choice questions, and discussions of the answers to the end-of-chapter clinical vignettes. Online resources include animations that expand on and clarify challenging topics and an interactive question bank to allow self-testing and exam review. Lippincott (R) Connect features: Lifetime access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, including interactive diagrams, video tutorials, flashcards, organ sounds, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

Cardiovascular diseases have a major impact in Western countries. Mathematical models and numerical simulations can help the understanding of physiological and pathological processes, complementing the information provided to medical doctors by medical imaging and other non-invasive means, and opening the possibility of a better diagnosis and more in-depth surgical planning. This book offers a mathematical update of the state of the art of the research in the field, and serves as a useful reference for the development of mathematical models and numerical simulation codes. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls; the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows

When it's hot outside, what can you do to stay cool? People have found many ways to cool off and cool down. How cool is that? Created in collaboration with the Smithsonian Institution, this STEAM book will ignite a curiosity about STEAM topics through real-world examples. It features a hands-on STEAM challenge that is perfect for makerspaces and that guides students step-by-step through the engineering design process. Make STEAM career connections with career advice from actual Smithsonian employees working in STEAM fields. This book builds young readers' early childhood literacy skills and is ideal for 1st grade students or ages 5-7.

Successfully learn to apply dental anatomy to the practice of dentistry with Wheeler's Dental Anatomy, Physiology, and Occlusion, 11th Edition. Updated and visually enhanced, the eleventh edition of this market-leading dental text expands its focus on clinical applications and includes dozens of online 360-degree and 3-D tooth animations to give you an unparalleled view of dentitions, pulp formation, the sequence of eruptions, and countless clinical considerations. Every text purchase also comes with access to the companion ExpertConsult website - where you can reference the entire text electronically as well as engage with a wealth of learning activities, animations, and hands-on resources to better understand and retain the information covered in your text. In all, this proven learning package offers all the up-to-date information, best practices, and tools to prepare you for the dental anatomy and occlusion section of the exams and ensure long-term clinical success. More than 800 full-color images include detailed, well-labeled anatomical illustrations as well as clinical photographs. Bolded key terms draw students' attention to essential terminology. Practical appendices include Review of Tooth Morphology with a concise review of tooth development from in utero to adolescence to adulthood; and Tooth Traits of the Permanent Dentition with tables for each tooth providing detailed information such as tooth notation, dimensions, position of proximal contacts, heights, and curvatures. 360-degree virtual reality and 3-D animations on Expert Consult help students refine their skills in tooth identification and examination. Step-by-step videos on Expert Consult demonstrate occlusal adjustments. Labeling exercises challenge students to identify tooth structures and facial anatomy with drag-and-drop labels. Chapter on clinical applications includes practical applications and case studies to prepare students for exams. Topics include root planing and scaling; extraction techniques and forces; relationship of fillings to pulp form and enamel form; and occlusal adjustment of premature occlusal contacts and arch form in relationship to bite splint designs. NEW! Learning objectives and pre-test questions at the start of every chapter focus students' attention on the knowledge and critical thinking expectations for each chapter. NEW! Full-color images have replaced many of the black and white images to give students a more vivid picture of clinical situations and procedures. NEW! Updated information incorporates new research and visuals to ensure students are equipped with the latest best practices. NEW! Access to the companion Expert Consult website includes hands-on exercises, animations, videos, quizzes, exams, and more to round out students' learning experience and help ensure their ability to apply book content.

Here's the ideal companion to Understanding Anatomy & Physiology: A Visual, Interactive Approach, 3rd Edition or as a stand-alone guide to reinforce A&P concepts. Hands-on activities make mastering A&P easier and fun! All answers can be found in the Instructor resources online. "Love this workbook! I would recommend this to any high school or college student taking anatomy, even if it is not required for your course." - Cheyenne, reviewer on Amazon "Get this workbook! Great tool to go along with the book, would highly recommend!" - Stacy W., reviewer on Amazon *Student Workbook answers are available for Instructors only

The publication of "Vanadium: Biochemical and Molecular Biological Approaches" is particularly timely as it exactly coincides with the centennial anniversary of the discovery of vanadium by Professor Henze, in the blood cells of an ascidian (tunicate) collected in Gulf of Naples in 1911. Vanadium, atomic number 23, covers a wide range of oxidation states (from -2 to +5) and has unpaired electrons. Depending on these properties, a wide variety of enzymes and compounds containing vanadium have been found and the biochemical behaviour of vanadium has been investigated extensively.

This monograph provides not only the basic properties and recent advances of vanadium chemistry but also presents recent topics on hyper-accumulators of vanadium, enzymatic roles of vanadium, biochemical functions of vanadium and medicinal functions of vanadium, which have been discovered by Biochemical and Molecular Biological Approaches.

"Vanadium: Biochemical and Molecular Biological Approaches" is aimed at pure and applied chemists, biochemists, pharmaceutical and medical scientists.

This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

The success of any space flight mission depends not only on advanced technology but also on the health and well-being of crew members. This book, written by an astronaut physician, is the first practical guide to maintaining crew members health in space. It combines research results with practical advice on such problems as bone loss, kidney stones, muscle wasting, motion sickness, loss of balance, orthostatic intolerance, weight loss, and excessive radiation exposure. Additional topics include pre-flight preparation, relevant gender differences, long-duration medical planning, post-flight rehabilitation, and the physiology of extra-vehicular activity. Designed as a handbook for space crews, this text is also an invaluable tool for all the engineers, medical personnel, and scientists who plan and execute space missions.

Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop.

Ideal as a companion to the text. Perfect as a stand-alone study guide. Body system by system, the exercises and activities you'll find inside will help you to master the basics of anatomy and physiology. Complete the corresponding sections of the Workbook as you proceed from topic to topic in class. See what students are saying online... Cut my study time in half! "This workbook cut my study time in half and helped me to be better prepared for the exam. I was shocked when my score went from 80 to 90 just after one exam!" Great workbook and super easy to understand. "Great workbook and super easy to understand. I love the layout of it and the work in the book follows right along with the book !!! I love it!!" - Brittany S. *Student Workbook answers are available for students in the back of the book

The book introduces readers to the concept of weightlessness and microgravity, and presents several examples of microgravity research in fluid physics, the material sciences and human physiology. Further, it explains a range of basic physical concepts (inertia, reference frames, mass and weight, accelerations, gravitation and weightiness, free fall, trajectories, and platforms for microgravity research) in simple terms. The last section addresses the physiological effects of weightlessness. The book's simple didactic approach makes it easy to read: equations are kept to a minimum, while examples and applications are presented in the appendices. Simple sketches and photos from actual space missions illustrate the main content. This book allows readers to understand the space environment that astronauts experience on board space stations, and to more closely follow on-going and future space missions in Earth orbit and to Mars.

Why do we eat? Is it instinct, or some other impetus? Despite the necessity of food, anxieties about what and how to eat are widespread in our culture, and scientists and physicians continue to have shifting theories about the phenomenon of appetite and its causes and norms. In Appetite and Its Discontents, Elizabeth A. Williams charts the history of inquiry into appetite between 1750 and 1950, as scientific and medical concepts of appetite shifted alongside developments in physiology, natural history, psychology, and ethology. Williams argues that trust in appetite was undermined in the mid-eighteenth century, when researchers who investigated ingestion and digestion began claiming that science alone could say which ways of eating were healthy and which were not. Tracing nineteenth- and twentieth-century conflicts over the nature of appetite, Williams explores contemporary worries about eating through the lens of science and medicine to show us how appetite--once a matter of personal inclination--became an object of science.

Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.

Punctuated with remarkable case studies, this book explores extraordinary encounters between hermaphrodites--people born with "ambiguous" sexual anatomy--and the medical and scientific professionals who grappled with them. Alice Dreger focuses on events in France and Britain in the late nineteenth century, a moment of great tension for questions of sex roles. While feminists, homosexuals, and anthropological explorers openly questioned the natures and purposes of the two sexes, anatomical hermaphrodites suggested a deeper question: just how many human sexes are there? Ultimately hermaphrodites led doctors and scientists to another surprisingly difficult question: what is sex, really? Hermaphrodites and the Medical Invention of Sex takes us inside the doctors' chambers to see how and why medical and scientific men constructed sex, gender, and sexuality as they did, and especially how the material conformation of hermaphroditic bodies--when combined with social exigencies--forced peculiar constructions. Throughout the book Dreger indicates how this history can help us to understand present-day conceptualizations of sex, gender, and sexuality. This leads to an epilogue, where the author discusses and questions the protocols employed today in the treatment of intersexuals (people born hermaphroditic). Given the history she has recounted, should these protocols be reconsidered and revised? A meticulously researched account of a fascinating problem in the history of medicine, this book will compel the attention of historians, physicians, medical ethicists, intersexuals themselves, and anyone interested in the meanings and foundations of sexual identity.

O2 in Vascular Disease: Leukocyte Activation and Toxic Oxygen Metabolites/Free Radicals; J.J.F. Belch, P. Hickman.. O2 Transport in Tumours: Oxygen Tension in Primary Tumours of the Uterine Cervix and Lymph Node Metastases of the Head and Neck; H. Lyng, et al. Hyperoxia and Hypoxia: New Horizons in Hyperbaric Oxygnation; P.B. James. O2 Transport in Organs: Brain: Haemoglobin Oxygenation Changes during Visual Stimulation in the Occipital Cortex; J. Ruben, et al. O2 Transport in Organs: Heart and Lung: Relatioship between Regional Myocardial Oxygenation and Function diring Acute Ischemia Supported by Selective Sunction and Retroinfusion (SSR) in Pigs; G. von Degenfeld, et al. O2 Transport in Organs: Skeletal Muscle: Blood Oxygen Desaturation Heterogeneity during Muscle Contraction Recorded by Near Infrared Spectroscopy; P.G. Cooper, et al. Systemic O2 Transport: Local Regulation of O2 Supply: Cellular Metabolic State in Vivo: Fluorocarbons: Functional Imaging: Perfusion and Diffusion Imaging and Spectroscopy: Methods and Instrumentation: Theoretical Models: 92 Additional Articles. Index.

Anatomy & Physiology: The Unity of Form and Function tells a story comprised of many layers, including core science, clinical applications, the history of medicine, and evolution of the human body. Saladin combines this humanistic perspective on anatomy and physiology with vibrant photos and art to convey the beauty and excitement of the subject. To help students manage the tremendous amount of information in this introductory course, the narrative is broken into short segments, each framed by expected learning outcomes and self-testing review questions.

Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function-a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders.

Association of American Publishers (AAP) Finalist for the 2020 PROSE Award Association of American Publishers (AAP) Subject Category Winner for the 2020 PROSE Award 2019 Taylor & Francis Award Winner for Outstanding Professional Book! Human Body: A Wearable Product Designer's Guide, unlike other anatomy books, is divided into sections pertinent to wearable product designers. Two introductory chapters include many definitions, an introduction to anatomical terminology, and brief discussions of the body's systems, setting the stage for the remaining chapters. The book is extensively referenced and has a large glossary with both anatomical and design terms making it maximally useful for interdisciplinary collaborative work. The book includes 200 original illustrations and many product examples to demonstrate relationships between wearable product components and anatomy. Exercises introduce useful anatomical, physiological, and biomechanical concepts and include design challenges. Features Includes body region chapters on head and neck, upper torso and arms, lower torso and legs, the mid-torso, hands, feet, and a chapter on the body as a whole Contains short sections on growth and development, pregnancy, and aging as well as sections on posture, gait, and designing total body garments Describes important regional muscles and their actions as well as joint range of motion (ROM) definitions and data with applications to designing motion into wearable products Presents appendices correlating to each body region's anatomy with instructions for landmarking and measuring the body, a valuable resource for a lifetime of designing For product design examples based on the book go to: https://www.uosportsproductdesign.com/humananatomy-sportsproductdesign-sokolowski-labat

Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. The proceedings provide new insights and concepts gained by molecular, cellular and neuroendocrine research into mechanistic interactions of the reproductive and somatotrophic axes. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; sex steroids, growth hormone releasing factor, and somatostatin; how sex steroids modulate growth hormone action on target issues; and differential effects of growth hormone secretagogues in men and women. This volume is designed for physicians, scientists and other health professionals interested or trained in clinical and basic endocrinology, growth or reproduction.

Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but are not limited to, procoagulant and anticoagulant actions that affect the coagulation cascade and platelet aggregation, as well as altering vasodilatory responses. In all these various animals, these mechanisms have evolved to perfection over millions of years to support their survival. In last 3-4 decades, due to the efforts of scientists from various backgrounds including biology, protein chemistry, molecular biology, pharmacology, hematology, and structural biology, significant progress in understanding the structure-function relationships, as well as the mechanism of action have been made in a number of exogenous factors that affect blood coagulation, platelet aggregation and vasodilation from various animals. These exogenous factors have contributed significantly to the development of research tools as well as providing new therapeutic agents. With the increase average age of the population coupled with changes in life style in recent years, there has been a significant increase in cardiovascular and hematological disorders. Thus scientists in both academic institutions as well as the pharmaceutical industry are developing better therapeutic agents to improve the quality of life. This impetus has lead to the search for novel agents from various sources that interfere with cardiovascular and hematalogical processes. Although at first glance exogenous factors appear to function as 'villains', several life-saving drugs have been developed based upon these factors. Such drugs or drug leads include those that inhibit the angiotensin converting enzymes (Captopril and Enalapril), that block platelet receptors (Eptifibatide and Tirofiban), or that digest thrombotic plugs (Alfimeprase and bat plasminogen activator) to name a few. Several new and exciting success stories are currently unfolding. In this book, recent studies on some of the exogenous factors that play crucial roles in cardiovascular and hematological disorders are reviewed in order to consolidate the efforts in this area of research and to recruit new, talented researchers. The 25-30 review chapters, each written by experts in their field, compiled herein are devoted to exogenous factors affecting platelet aggregation, anticoagulant and procoagulant proteins, fibrinolytic proteins and hypotensive agents (For details see, Contents of the Book). This book is intended to help to create elevated awareness and enthusiasm in the field of exogenous factors. I believe that this book will provide greater impetus to the search for novel proteins based on naturally occurring exogenous factors. This will be the first book dealing extensively with exogenous factors in the last 25 years. The book will provide a ready reference to the different approaches used to solve complex problems in protein chemistry and pharmacology of exogenous factors. The book will update our understanding of the structure-function relationships and mechanisms of action of exogenous factors and provide great insights into future directions for solving the remaining challenges.