Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

Starting out in practice can be difficult and confusing. This guide for newly qualified occupational therapists provides an authoritative overview of what to expect in your role and work settings, and is full of practical guidance on how to make a good start to a successful practice. With chapters by experienced practitioners in the field, it offers insights into work in paediatrics, mental health, learning disability and the acute hospital setting. Vital information is also included on difficult aspects of practice such as legislation and data protection. It signposts sources for support and resources for furthering techniques in individual areas of work. Most importantly, the book offers tips for managing a busy workload, while building the positive relationships and resilience needed for a successful career in the occupational therapy.

This title includes a number of Open Access chapters. Child obesity is a serious condition that affects children around the world in growing numbers. With obesity comes an increased risk of other chronic diseases as well, making it even more important to understand and treat this condition from a variety of angles. This current volume seeks to understand the phenomenon of child obesity and presents a range of viewpoints on its prevalence, causes, and treatments. The different sections contained within explore the following topics: * The worldwide prevalence of childhood obesity and its growing effect on children * The causes of childhood obesity and the complex interactions of genetic, environmental, social, and medical factors that contribute to its development * Proposed treatments, some intervention-based and others that aim to change how food is marketed and sold to youth This reference volume offers a comprehensive and thorough guide to a field that is rapidly expanding and points to new directions in research and public policy. Edited by a doctor with extensive experience as a researcher, writer, and medical practitioner, The Childhood Obesity Epidemic is an authoritative and easy-to-use reference that provides resources for researchers in the field, students, and anyone who wishes to gain an overview to this important field of study.

This title includes a number of Open Access chapters. Childhood obesity is a major public health crisis nationally and internationally. This insightful compendium provides valuable information and assesses the research foundations behind several school initiatives to help combat the epidemic of obesity in children and adolescents, particularly using interventions to increase physical activity. The book looks at the issue from three levels: first, the effects of unhealthy eating and lack of exercise on a number of health outcomes in children and adolescents; second, successful small- and large-scale school-based interventions; and finally, synthesis of current literature and translation into specific guidelines and recommendations. Specific topics addressed in the book include: * The appeal and benefits of outdoor versus indoor activity * Cultural differences in physical activity * Successful interventions and their continued success, or lack of, after several years * The roles of family and community interventions * Staff involvement in children's physical activities * Specific programs, such as Plant Health, an antismoking intervention with unintended obesity intervention * Establishing healthy habits in youth This research provides schools with a strong foundation for implementing policies and practices that support healthy eating and regular physical activity. In the process, educators will be ensuring the best possible chance for increasing students' academic success, improving both physical and mental health, and decreasing the risk for myriad chronic diseases.

Why is music so important to most of us? How does music help us both in our everyday lives, and in the more specialist context of music therapy? This book suggests a new way of approaching these topical questions, drawing from Ansdell's long experience as a music therapist, and from the latest thinking on music in everyday life. Vibrant and moving examples from music therapy situations are twinned with the stories of 'ordinary' people who describe how music helps them within their everyday lives. Together this complementary material leads Ansdell to present a new interdisciplinary framework showing how musical experiences can help all of us build and negotiate identities, make intimate non-verbal relationships, belong together in community, and find moments of transcendence and meaning. How Music Helps is not just a book about music therapy. It has the more ambitious aim to promote (from a music therapist's perspective) a better understanding of 'music and change' in our personal and social life. Ansdell's theoretical synthesis links the tradition of Nordoff-Robbins music therapy and its recent developments in Community Music Therapy to contemporary music sociology and music studies. This book will be relevant to practitioners, academics, and researchers looking for a broad-based theoretical perspective to guide further study and policy in music, well-being, and health.

Gain the solid foundation in A&P that you need to provide effective respiratory care! Respiratory Care Anatomy and Physiology, 5th Edition provides an in-depth understanding of the physiology and pathophysiology of the lungs, heart, vascular system, and kidneys. It connects theory with practice, showing how physiological principles guide the selection and use of diagnostic, therapeutic, and monitoring procedures. New to this edition are clinical scenarios for issues such as vaping and the addiction pathway. Written by noted educator Will Beachey, this book uses a body systems approach and a unique clinical focus to help you think like a clinician and succeed as a respiratory care professional. Clinical Focus boxes relate the material to real-life situations in health care, showing the practical importance of understanding physiological concepts. Concept Questions stimulate critical thinking in a clinical context with open-ended, self-assessment questions. Chapter outlines, learning objectives, key terms, and bulleted Points to Remember highlight the most important concepts and ideas in each chapter. Appendixes make it easy to locate symbols and abbreviations, units of measurement, equation derivations, and a Dubois body surface area chart. NEW! Clinical Focus scenarios are all revised and updated, and new scenarios are added on topics including the effects of electronic nicotine devices (vaping) on the lung, the addiction pathway and the counseling role of the respiratory therapist, pulse CO oximeter use at the bedside, non-invasive assessment of the oxygenation deficit (A-a O2 difference), early prone positioning of the non-intubated patient with COVID-19, and Transcatheter Aortic Valve Replacement (TAVR). NEW! Updated Physiological Basis for Oxygenation and Mechanical Ventilation Strategies chapter covers pathophysiology and supportive care of SARS-CoV-2 (COVID-19) ARDS and the concepts of stress, strain, driving pressure, and the mechanical power of ventilation as they relate to the prevention of ventilator-induced lung injury (VILI). NEW! Updated GINA 2020 asthma guidelines address the use of a long-acting beta agonist (LABA)-inhaled corticosteroid (ICS) combination in emergency rescue situations. NEW! Updated coverage of phrenic nerve stimulation examines the obtaining of transdiaphragmatic twitch pressure (Pditw) in the assessment of ventilatory fatigue.

Challenging the idea that the corporate 'war' against childhood obesity is normal, necessary, or harmless, this book exposes healthy lifestyles education as a form of mis-education that shapes how students learn about health, corporations, and consumption. Drawing on ethnographic research and studies from across the globe, this book explores how corporations fund, devise, and implement various programmes in schools as 'part of the solution' to childhood obesity. Including perspectives from children, teachers, school leaders, and both public and private external providers on how children's health and 'healthy consumption' is understood and experienced, this book is divided into eight accessible chapters which include: Schooling the childhood obesity 'crisis'; The corporate 'gift' of healthy lifestyles; 'Coming together' to solve obesity; Learning about health, fatness, and 'good' choices; and Shaping the (un)healthy child-consumer Schools, Corporations, and the War on Childhood Obesity is the perfect resource for postgraduate students and academics working in the public health or education field, or those taking courses on the sociology of education, health and physical education, curriculum, pedagogy, ethnography, or critical theory, who are looking to gain an insight into the current situation surrounding obesity and health in corporations and schools.

The only available resource to provide cutting-edge, in-depth coverage of the links between obesity and anesthesia in surgery, the reader-friendly Handbook of Perioperative Anesthesia: Complications and Challenges of the Obese Patient guides the practicing anesthesiologist through each stage of surgery for the obese patient. This clinically relevant text thoroughly illustrates the unique challenges and complications the anesthesiologist faces when supervising and administering drug delivery during surgery. Practical and hands-on, this source also advises the anesthesiologist on how to avoid potential risks and ensure speedy patient recovery post-operation. Easily referenced, this handbook clearly addresses treatment and management of the obese patient in the three chronological stages of surgery: Preoperative - includes information on systemic patient evaluation and surgery preparation, emphasizing related areas of concern in the obese patient (cardiac, pulmonary, endocrine, and others) to help the anesthesiologist foresee how a patient will fare during surgery Intraoperative - provides a thorough discussion of the latest in procedural technique, drug and fluid administration, patient monitoring, and airway management Postoperative - steps the anesthesiologist can take following surgery to optimize patient results In addition, this handbook explores special situations that anesthesiologists may encounter during surgery, including the needs of pregnant and pediatric patients, as well as patients with needs outside of the hospital setting.

Obesity is a continuing issue around the world and in many contexts. The growing number of obese people is an increasing concern for those in the medical profession, and obesity can pose specific challenges in relation to fertility and pregnancy. Patients who are obese require specific considerations and knowledge. Bringing together experts from a variety of specialties to examine the issues and challenges of obesity, this book discusses how obesity affects fertility, reproduction, and pregnancy. Beginning with an exploration of the epidemiology of obesity, further chapters focus on specific issues related to obesity and both male and female reproduction, the complications of obesity during pregnancy and labour, and the long term effects of obesity. This is the most comprehensive resource to examine the topic of obesity and reproductive issues, making it invaluable for medical students, professionals, and researchers in public policy and medicine.
Comprehensive examination of fertility issues arising from male and female obesityClinical knowledge and expertise given to the subjectsIn-depth examination through 47 chapters of a growing, but often overlooked, issue in fertility and pregnancy

Food and nutrients are the original medicine and the shoulders on which modern medicine stands. But in recent decades, food and medicine have taken divergent paths and the natural healing properties of food have been diminished in the wake of modern technical progress. With contributions from highly regarded experts who work on the frontlines of disease management, the bestselling first edition of Advancing Medicine with Food and Nutrients, Food and Nutrients in Disease Management effectively brought food back into the clinical arena, helping physicians put food and nutrients back on the prescription pad. Board-certified in General Preventive Medicine, Ingrid Kohlstadt, MD, MPH has been elected a Fellow of the American College of Nutrition and a Fellow of the American College of Preventive Medicine. Guided by Dr. Kohlstadt, this authoritative reference equips clinicians with the information they need to fully utilize nutritional medicine in their practice. New in the Second Edition Toxic exposures such as molds, microbial infections, xenoestrogens, heavy metals, and inert nanoparticles Food safety issues: precautions for patients with preexisting medical conditions, adequate labeling of food allergens such as gluten, potential adverse effects of artificial sweeteners, consequences of applying ionizing radiation to food, food-borne mycotoxins, critical food restrictions following bariatric surgery, precautions for preparing food in the home Consumer advocacy issues on navigating claims of medical foods and dietary supplements Physical forces on nutritional needs, such as ultraviolet light initiating vitamin D synthesis, non-ionizing radiation's effects on brain glucose metabolism and excess body fat's effects on inflammation and hydration Preventive medicine and how to preserve resiliency at the individual and public health levels Written by doctors for doctors, Advancing Medicine with Food and Nutrients, Second Edition reunites food and medicine. Buttressed with new evidence, leading physicians on the frontlines of disease management apply the latest scientific advances to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side effects, improved risk reduction, or added quality of life. An article by Ingrid Kohlstadt on education and nutrition appeared in TIME Magazine online on November 12, 2014.

Advances and Techniques in Restoration Therapy focuses on the practical elements of the Restoration Therapy Model to help mental health professionals working with individuals, couples, and families, to restore broken identities and senses of safety, and to move toward action that is functional and healing. Richly illustrated with case examples from experienced clinicians, this volume brings new insights and a range of established and emerging therapeutic techniques to the framework and Restoration Therapy community. This is an innovative and much-needed step-by-step manual, which will provide marriage and family therapists and counselors with practical ways of applying key interventions to varied situations of pain, to help clients find functional, healing solutions with integrity.

In this issue of Physical Medicine and Rehabilitation Clinics, guest editor Dr. Thomas (Quin) Throckmorton brings his considerable expertise to Shoulder Rehabilitation. Top experts in the field cover key topics such as shoulder impingement syndrome; non-operative treatment of rotator cuff tears; post-operative rehabilitation following rotator cuff repair; non-operative treatment of the biceps-labral complex; post-operative rehabilitation after SLAP repair; and more. Contains 12 relevant, practice-oriented topics including post-operative rehabilitation after surgery for shoulder instability; scapular dyskinesis; adhesive capsulitis; post-operative rehabilitation after shoulder arthroplasty; muscular re-training and rehabilitation after tendon transfer surgery in the shoulder; and more. Provides in-depth clinical reviews on shoulder rehabilitation, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Psychodrama: Advances in Theory and Practice provides a comprehensive overview of developments in the theory and practice of psychodrama, integrating different psychodramatic schools of thought.

Psychodrama is one of the pioneering approaches of psychotherapy and is practised by thousands of practitioners and in most countries of the world. The editors of this volume bring together contributions from Europe, South America, Australia, Israel and the USA to explain and explore recent innovations. They look at how psychodrama has contributed to the development of psychotherapy, introducing concepts that have had a profound influence on other therapies. These include concepts such as role theory, the encounter, the co-unconscious, the social atom, sociometry, action research, group psychotherapy, the cycle of spontaneity and creativity, role play and many related concepts and techniques.

This book will be of great interest to all students, practitioners and trainers in the field of psychodrama. It will also appeal to professionals and students in the related fields of psychotherapy, counselling, psychology and psychiatry.

Inflammation and Obesity: A New and Novel Approach to Manage Obesity and its Consequences is a comprehensive and up-to-date exploration of the correlation between obesity and inflammation. From the pathophysiology of obesity and inflammation, to the molecular mechanisms of obesity induced chronic inflammation, the book discusses how obesity and inflammation interact with other diseases. It highlights the hidden risk factors of obesity induced chronic inflammation, provides specific patient management guidelines regarding the higher inflammatory response in patients, and concludes with new therapeutic strategies to address inflammation in obese patients.

The Link between Obesity and Cancer provides a comprehensive review on the relationship between obesity and cancer, presenting global perspectives on obesity and cancer incidence that are followed by in-depth discussions on cancers for which we have new evidence of a causal relationship with obesity. Readers will gain fundamental knowledge on which cancer types are related to obesity. In addition, this updated resource provides significant knowledge for clinicians on when to act, along with specific management guidelines for patients, as well as how to understand potential risk factors and how to directly or indirectly minimize these risks. The book also provides never-before-published scientific data for any researcher in the field, identifying molecular mechanisms and links behind the development of malignancy and promoting research in new and effective target pathways in developing therapeutic strategies.

What is it like to live with a chronic illness? How can counselors support those living with one? Allan Hugh Cole Jr. offers answers to these two questions and so many more in Counseling Persons with Parkinson's Disease. In ten succinct chapters, Cole offers a glimpse into life with Parkinson's and presents an insightful approach to counseling someone living with a chronic illness. Cole was diagnosed with Parkinson's Disease in 2016, and-though it hardly happened overnight-he has since discovered a new passion and drive for life. A teacher of social workers and counselors for many years, Cole has unique insight into chronic illness and the care required to help someone diagnosed with one. He delves into the importance of accepting a chronic illness and how this can create an opportunity for personal transformation, newfound meaning, and rejuvenated purpose. In addition to emphasizing the importance of self-reflection, he also offers evidence-based approaches to counseling. Cole's approaches to counseling draw on task-centered social work practice. Throughout the book, he engages with five purposeful actions tied to principles of constructivism, Aristotelian thought, American pragmatism, and theories of interpretation (hermeneutics). At once informative, realistic, humorous, and hopeful, this is a thoughtful guide for clinicians who give counsel, educators who teach counseling, people supporting someone else, and anyone living with a chronic illness.

Challenging the idea that the corporate 'war' against childhood obesity is normal, necessary, or harmless, this book exposes healthy lifestyles education as a form of mis-education that shapes how students learn about health, corporations, and consumption. Drawing on ethnographic research and studies from across the globe, this book explores how corporations fund, devise, and implement various programmes in schools as 'part of the solution' to childhood obesity. Including perspectives from children, teachers, school leaders, and both public and private external providers on how children's health and 'healthy consumption' is understood and experienced, this book is divided into eight accessible chapters which include: Schooling the childhood obesity 'crisis'; The corporate 'gift' of healthy lifestyles; 'Coming together' to solve obesity; Learning about health, fatness, and 'good' choices; and Shaping the (un)healthy child-consumer Schools, Corporations, and the War on Childhood Obesity is the perfect resource for postgraduate students and academics working in the public health or education field, or those taking courses on the sociology of education, health and physical education, curriculum, pedagogy, ethnography, or critical theory, who are looking to gain an insight into the current situation surrounding obesity and health in corporations and schools.

Physiotherapy for the Hip Joint offers consolidated, current coverage of recent advances on various musculoskeletal hip conditions related to physiotherapy. Drs. Patitapaban Mohanty and Monalisa Pattnaik provide thorough, focused information on coxa valga, coxa vara, anteversion, retroversion, pelvic tilt, osteoarthritis, rheumatoid arthritis, and more. Physical medicine and rehabilitation specialists, physiotherapists, and orthopaedic surgeons will find this unique, concise title to be useful in everyday practice settings. Includes introductory chapters covering anatomy and biomechanics. Offers comprehensive coverage of hip conditions from trauma to deformities to post-surgical rehabilitation. Discusses clinical reasoning for posterior hip pain, piriformis syndrome, sacroiliac joint dysfunction, lumbar radiculopathy and meralgia paresthetica. Consolidates today's available information on this timely topic into a single, convenient resource.

The obesity epidemic is one of the most serious public health threats confronting the nation and the world. The majority of overweight individuals want to lose weight, but the overall success of self-administered diets and commercial weight loss programs is very poor. Scientific findings suggest that the problem boils down to adherence. The dietary and physical activity recommendations that weight loss programs promote are effective; however, people have difficulty initiating and maintaining changes. Effective Weight Loss presents 25 detailed sessions of an empirically supported, cognitive-behavioral treatment package called Acceptance-Based Behavioral Treatment (ABT). The foundation of this approach is comprised of the nutritional, physical activity, and behavioral components of the most successful, gold-standard behavioral weight loss programs. These components are synthesized with acceptance, willingness, behavioral commitment, motivation, and relapse prevention strategies drawn from a range of therapies. ABT is based on the idea that specialized self-control skills are necessary for weight control, given our innate desire to consume delicious foods and to conserve energy by avoiding physical activity. These self-control skills revolve around a willingness to choose behaviors that may be perceived as uncomfortable, for the sake of a more valuable objective. The Clinician Guide is geared towards helping administer treatment, and the companion Workbook provides summaries of session content, exercises, worksheets, handouts, and assignments for patients and clients receiving the treatment. The books will appeal to psychologists, primary care physicians, nutritionists, dieticians, and other clinicians who counsel the overweight.

Exploring the impact of the built environment and design on people with a range of neurological experiences, including autism, dementia, dyslexia and dyspraxia, this comprehensive guide provides project commissioners, architects and designers with all the information and personal insight they need to design, create and build 'mind-friendly' environments for everyone. Assimilating knowledge from medical, therapeutic, social and educational spheres, and using sensory integration theory, the book explores the connection between our minds and our surroundings and considers the impact of the environment on the senses, well-being and neurodiverse needs of people. The book shows how design adaptations to lighting, acoustics, temperature, surfaces, furniture and space can positively benefit the lives of everyone across a range of environments including workplaces, retail, sport and leisure, domestic, educational institutions, cultural and civic spaces, outdoor spaces and places of worship. Universal in its approach and written by an experienced architect and inclusive design consultant, this book is essential reading for professionals in architecture and design, education, organisational psychology, business management and occupational therapy.

Yoga Therapy: Theory and Practice is a vital guidebook for any clinician or scholar looking to integrate yoga into the medical and mental health fields. Chapters are written by expert yoga therapy practitioners and offer theoretical, historical, and practice-based instruction on cutting-edge topics such as application of yoga therapy to anger management and the intersection of yoga therapy and epigenetics; many chapters also include Q&A "self-inquiries." Readers will find that Yoga Therapy is the perfect guide for practitioners looking for new techniques as well as those hoping to begin from scratch with yoga therapy.

Here is the most comprehensive orthopedic textbook for physical therapist assistant students. First laying the foundation of the role of the PTA within the orthopedic plan of care, this text offers students the fundamental knowledge needed to best understand how the PT evaluates a patient. From principles of tissue healing to detailed descriptions of the most common pathologies, tests and interventions for each body region, this text prepares the PTA for best patient education and care.

Speech and language therapists are becoming increasingly involved in working with people who have progressive neurological disorders such as Parkinson's disease. This management pack encompasses initial assessment, regular reviews, support for both client and carer and the possibility of individual or group therapy. The programme is designed to give a framework for setting up and running a comprehensive speech/language therapy service for those with Parkinson's disease and related conditions. The first section considers some theoretical issues associated with Parkinson's disease and Parkinsonism explaining terminology and common drugs used for these conditions. It also describes the management programme insome detail, and gives suggestions for increasing referral rates to speech/language therapy. The second section provides all the information needed to run the course, including helpful hints on do's and don'ts, a timetable of all the necessary activities and photocopiable standard letters and forms. The final section is the information pack that is given to participants. It includes exercises to improve facial expression, breathing, volume of voice, speed of speech and stress, intonation and some ideas to help eating and drinking.

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Drs Darren Rosenberg and Craig Rovito, will discuss a number of important topics related to Polio. This issue of one of four issues selected each year by series Consulting Editor, Santos Martinez. Topics discussed in this issue include, but are not limited to: epidemiology and working toward eradication; Polio-like diseases, AFM; Approach to fatigue and Energy Conservation; Bracing: upper and lower limb orthoses; NCS/EMG- common neuropathies and considerations for a patient with polio; Joint and back pain; Scoliosis; Respiratory complications; Psychiatric outcomes and approach; Palliative and end of life discussions and considerations; Patient information: resources and community reintegration; and Medical combordities and complications associated with polio.