What State Do You Live In explains the events that take place in your body if you lose control over your weight. Tens of millions of adult Americanssuffer from weight related chronic disease states including pre-diabetes, high blood pressure, abnormal blood cholesterol, the metabolic syndrome, andtype II diabetes. If you are overweight and suffer from high blood glucose, you're suffering from insulin resistance and need to read this story.

What State Do You Live In begins with you in the normal state, when insulin is in complete control over blood glucose and blood fat levels. Itprogresses into the insulin resistant state which describes in detail the events that stem from weight related insulin resistance including elevatedtriglycerides, high blood pressure, unhealthy cholesterol, the metabolic syndrome, and type II diabetes.

What State Do You live In is different from other books. It provides you with realistic expectations. It does not suggest pills, supplements, or anyother form of synthetic nutrition as a means to reverse faulty nutrition. It does offer you more than a single solution to begin reversing the insulinresistant state, including the lower carbohydrate approach to improve high blood glucose.

What State Do You Live In provides you with five different levels of food strategies to put you back in control of your blood glucose. Don't ignorehigh blood glucose, if left untreated, the consequences are life threatening.

Nutrition in the Prevention and Treatment of Abdominal Obesity, Second Edition focuses on the important role that exercise, dietary changes and foods play in promoting and reducing visceral fat. Nutritionists, dieticians and healthcare providers seeking to address the abdominal obesity epidemic will find this book to be a valuable resource in their long-term goal of preventing chronic diseases, especially heart, vascular and diabetic diseases. Chapters define a range of dietary approaches to reduce risk for the associated chronic diseases. In addition, discussions of the importance of dietary approaches to reduce abdominal obesity, along with clinical approaches, are discussed, including costs and risks.

Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology

Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, "Medicinal Chemistry of Nucleic Acids" presents a thorough overview of nucleic acid chemistry--a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids--such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs--to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes:

In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry

A close look at a large range of current topics on nucleic acid chemistry and biology

Essential information on the use of nucleic acid drugs to treat diseases like cancer

A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area

Thorough in its approach and promising in its message, "Medicinal Chemistry of Nucleic Acids" probes the new domains of pharmaceutical research--and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.

Noncommunicable Diseases: A Compendium introduces readers to noncommunicable diseases (NCDs) - what they are, their burden, their determinants and how they can be prevented and controlled. Focusing on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world's biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs; (ii) the burden, epidemiology and priority interventions for individual NCDs; (iii) social determinants and risk factors for NCDs and priority interventions; (iv) global policy; (v) cross-cutting issues; and (vi) stakeholder action. Drawing on the expertise of a large and diverse team of internationally renowned policy and academic experts, the book describes the key epidemiologic features of NCDs and evidence-based interventions in a concise manner that will be useful for policymakers across all parts of society, as well as for public health and clinical practitioners.

This is a timely and informative updated edition for all health care providers challenged with helping patients manage weight. Similar to the well-reviewed first edition, this updated title is directed toward individuals who wish to read further about targeted topics, rather than find an introduction to the field. This second edition again provides insights into recent scientific advances in obesity research and provides the most up-to-date instruction about current treatment issues and strategies for both adults and children. While several of the chapters are no longer relevant from the first edition, other topics have emerged as interesting and current. This edition will keep the two-section format of Physiology and Pathophysiology and Clinical Management, but it increases the first section to 10 chapters and reduces the second section to 12 chapters. The plan is to keep this edition in the range of about 350 to 400, maximum, printed pages. The volume is again divided into two parts. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Expert authors discuss pathways that control food intake, energy expenditure and peripheral nutrient metabolism, including a look at the emerging evidence of the role of adipose tissue as an endocrine organ. Part 2 covers all the key issues central to clinical management, including recent developments in the epidemiology of obesity, assessment of the obese patient, behavioral strategies in weight management, dietary modification as a weight management strategy, physical activity as a weight management strategy, weight loss drugs, surgical approaches to obesity and other important clinical topics. An essential, practical text that sorts, synthesizes and interprets the latest information on obesity-related topics, this second edition will be an essential resource for clinical endocrinologists and other health care providers across a broad spectrum of specialties.

This book presents a comparison analysis of two cancer treatment therapies: carbon ion therapy and protontherapy. It is divided in 5 sections. The first ones gives the reader a brief history of Radiotherapy and types of radiation. In the second section, the techniques and equipments, including new ones in development such as Cyclinac , Laser and DWA, are described. The third section describes biophysical (such as stopping power and LET) and biological (such as RBE and OER) properties, the fundamental experiments and clinical area. The fourth section presents models and the fifth section compares both techniques, showing advantages and disadvantages of each, and their similarities.

Nutritional Pathophysiology of Obesity and Its Comorbidities: A Case-Study Approach challenges students and practitioners to understand the role of nutrients within the pathophysiology and development of disease, specifically those diseases which develop as a result of obesity. Through a case-based approach, the author presents complex clinical scenarios that require multiple treatment strategies, including targeted diet modification as an adjuvant to medical therapy. The book is divided into 9 modules and 5 appendices each of which covers aspects of obesity and its comorbidities. Within each module, a case is detailed with relevant history, laboratory and physical data, and follow-up information. Each case is followed by a resource section which delineates current understanding of the pathophysiology of the condition, as well as the actions of nutrients and food components shown to modify these processes. A "further readings" section cites current supporting clinical and basic literature as well as published guidelines.

Physiotherapy for the Hip Joint offers consolidated, current coverage of recent advances on various musculoskeletal hip conditions related to physiotherapy. Drs. Patitapaban Mohanty and Monalisa Pattnaik provide thorough, focused information on coxa valga, coxa vara, anteversion, retroversion, pelvic tilt, osteoarthritis, rheumatoid arthritis, and more. Physical medicine and rehabilitation specialists, physiotherapists, and orthopaedic surgeons will find this unique, concise title to be useful in everyday practice settings. Includes introductory chapters covering anatomy and biomechanics. Offers comprehensive coverage of hip conditions from trauma to deformities to post-surgical rehabilitation. Discusses clinical reasoning for posterior hip pain, piriformis syndrome, sacroiliac joint dysfunction, lumbar radiculopathy and meralgia paresthetica. Consolidates today's available information on this timely topic into a single, convenient resource.

A critical perspective on one of the major public health issues of the day Discusses both conceptual and practical issues Synthesizes a range of disciplinary perspectives Includes findings from primary research International author team

Discrimination based on body weight is an underestimated and widespread problem. There is not a single national law worldwide that prohibits weight discrimination, but quite a number of laws and policies that reinforce, or at least reflect, the existing socially ubiquitous weight stigma. This volume focuses on where and how fatness and law intersect, discussing current anti-discrimination protections related to fatness; the ongoing debate around the introduction of new anti-discrimination categories; national and international principles that seem to argue against the introduction of legal protection of fatness; the question whether fatness should be considered a disability; and weight stigma in legal practice. Starting from a fat studies perspective, this book also considers the legal implications of anti-discrimination legislation for fatness through an intersectional lens, noting how fatness often overlaps with other marginalized identities, including race and ethnicity, gender, and socioeconomic status. This book will be of interest to both professional and lay audiences, providing an introduction into the legal aspects of weightism, as well as offering solutions for legislative practice. It will be an invaluable resource for everyone who would like to be more weight-sensitive in their legal work. The chapters in this book were originally published as a special issue of Fat Studies: An Interdisciplinary Journal of Body Weight and Society.

The book describes how to use breathing as a medium for self-regulation and self-reflection and how balanced breathing thus helps to promote mental and physical health and alleviate symptoms resulting from imbalanced breathing. The authors describe applications of psychophysical breathing therapy in many areas of life, developed by both themselves and other professionals trained by them. The approach of the book is based on the interactional aspects between mind and body. A person's breathing style influences their relation both to themselves and to others - and vice versa, and thus mental and also physical health. A comprehensive theoretical description of the psychophysical regulation of breathing and the consequences of imbalanced breathing is complemented by material derived from the authors' extensive clinical experience. Psychological orientations used by the writers include object relations theories, and psychodynamic, cognitive, brief and group therapy theories. As a new aspect the writers introduce how breathing patterns are learnt in early interaction. The writers also acknowledge how physical factors affect and interact with psychological factors in producing imbalanced breathing.

This practical guide helps health or social care professionals across all settings to understand how important it is to prevent and manage their service users' overweight and obesity, and motivate them to achieve and maintain a healthy weight, so reducing their risk of associated health conditions such as diabetes and now COVID-19. Obesity and associated health problems represent a growing health burden around the world, with rates throughout Europe increasing sharply over the last forty years, second only to the United States and closely followed by many nations in Asia. The book will be an invaluable manual for general practice, primary care and community clinicians, practice and community nurses and dietitians and a go-to reference for health professionals across all medical specialties and related support services, as well as medical education, public health and social care worker professionals.

Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin.

School Food, Equity and Social Justice provides contemporary, critical examinations of policies and practices relating to food in schools across 25 countries from an equity and social justice perspective. The book is divided into three sections: Food politics and policies; Sustainability and development; and, Teaching and learning about food. Bringing together an interdisciplinary group of academics with practitioner backgrounds, the chapters in this collection broaden discussions on school food to consider its educational and environmental implications, the ideals of food in schools, the emotional and ideological components of schooling food, and the relationships with home and everyday life. Our aim is to provide enhanced insight into matters of social justice in diverse contexts, and visions of how greater equality and equity may be achieved through school food policy and in school food programs. We expect this book to become essential reading for students, researchers and policy makers in health education, health promotion, educational practice and policy, public health, nutrition and social justice education.

The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term "globesity" to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has too often been unachievable and unaffordable outside of established bariatric centers, but such centers themselves usually have insufficient capacity and resources to cope with growing demand. This book aims to provide guidance and helpful tips and tricks on how to deal with obese patients within a general surgery setting. Epidemiology, organizational and logistical aspects, nursing issues, patient assessment, anesthesiology, and surgical practicalities are expertly covered in the opening chapters. Techniques of relevance to the general surgeon are described according to anatomic region, covering the head and neck; cardiothoracic and vascular system; upper and lower GI tract; pancreas, liver and adrenal glands; urinary tract and kidneys; the reproductive system; and the abdominal wall. Results achieved by bariatric surgery worldwide are reviewed, and the book closes with a chapter devoted to plastic and reconstructive surgery. The Globesity Challenge to General Surgery highlights a need for global rethinking on public health as regards resource allocation and patterns and standards of care, improving outcomes through greater affordability.

The Overweight Mind and Body is a self-help guide to understanding the psychological issues that lead to overeating and weight gain. The book enables the reader to discover the psychological drives that lead to unwanted weight and to find ways of meeting those drives other than with food. It introduces a simple, user-friendly theory of Transactional Analysis to promote weight-related self-awareness. The author includes exercises that empower readers to uncover their own stories. She understands that, for many, carrying extra weight is emotionally and physically painful and so gently encourages readers to explore at their own level. She uses case studies to demonstrate the many unconscious influences on one's eating and how, when people discover and resolve these influences, they no longer need extra food. Reading them shows that "you are not alone". This book will also be of interest to, and a useful guide for, practitioners in the caring professions who work with clients struggling with eating and overweight.

The Overweight Mind and Body is a self-help guide to understanding the psychological issues that lead to overeating and weight gain. The book enables the reader to discover the psychological drives that lead to unwanted weight and to find ways of meeting those drives other than with food. It introduces a simple, user-friendly theory of Transactional Analysis to promote weight-related self-awareness. The author includes exercises that empower readers to uncover their own stories. She understands that, for many, carrying extra weight is emotionally and physically painful and so gently encourages readers to explore at their own level. She uses case studies to demonstrate the many unconscious influences on one's eating and how, when people discover and resolve these influences, they no longer need extra food. Reading them shows that "you are not alone". This book will also be of interest to, and a useful guide for, practitioners in the caring professions who work with clients struggling with eating and overweight.

This book offers a much-needed reframing of food discourse by presenting alternative ways of thinking about the changing politics of food, eating, and nutrition. It examines critical epistemological questions of how food knowledge comes to be shaped and why we see pendulum swings when it comes to the question of what to eat. As food facts peak and peril in the face of conflicting dietary advice and nutritional evidence, this book situates shifting food truths through a critical analysis of how healthy eating is framed and contested, particularly amid fluctuating truth claims of a "post-truth" culture. It explores what a post-truth epistemological framework can offer critical food and health studies, considers the type of questions this may enable, and looks at what can be gained by relinquishing rigid empirical pursuits of singular dietary truths. In focusing too intently on the separation between food fact and food fiction, the book argues that politically dangerous and epistemically narrow ideas of one way to eat "healthy" or "right" are perpetuated. Drawing on a range of archival materials related to food and health and interviews with registered dietitians, this book offers various examples of shifting food truths, from macro-historical genealogies to contemporary case studies of dairy, wheat, and meat. Providing a rich and innovative analysis, this book offers news ways to think about, and act upon, our increasingly complex food landscapes. It does so by loosening our empirical Western reliance on singular food facts in favour of an articulation of contextual food truths that situate the problems of health as problems of living, not as individualistic problems of eating. It will be of interest to students, scholars, and practitioners working in food studies, food politics, sociology, environmental geography, health, nutrition, and cultural studies.

Subtle-body practices are found particularly in Indian, Indo-Tibetan and East Asian societies, but have become increasingly familiar in Western societies, especially through the various healing and yogic techniques and exercises associated with them. This book explores subtle-body practices from a variety of perspectives, and includes both studies of these practices in Asian and Western contexts. The book discusses how subtle-body practices assume a quasi-material level of human existence that is intermediate between conventional concepts of body and mind. Often, this level is conceived of in terms of an invisible structure of channels, associated with the human body, through which flows of quasi-material substance take place. Contributors look at how subtle-body concepts form the basic explanatory structure for a wide range of practices. These include forms of healing, modes of exercise and martial arts as well as religious practices aimed at the refinement and transformation of the human mindbody complex. By highlighting how subtle-body practices of many kinds have been introduced into Western societies in recent years, the book explores the possibilities for new models of understanding which these concepts open up. It is a useful contribution to studies on Asian Religion and Philosophy.

A critical perspective on one of the major public health issues of the day Discusses both conceptual and practical issues Synthesizes a range of disciplinary perspectives Includes findings from primary research International author team

Nowadays, a plethora of treatment technologies is available to the consumer, each employing a variety of concepts of the body, self, sickness and healing. This volume explores the options, strategies and consequences that are both relevant and necessary for patients and practitioners who are manoeuvring this medical plurality. Although wideranging in scope and covering areas as diverse as India, Ecuador, Ghana and Norway, central to all contributions is the observation that technologies of healing are founded on socially learned and to some extent fluid experiences of body and self.

Maha Nasrallah-Babenko presents a culturally sensitive and uniquely accessible guide that equips clinicians, student sex therapists, and female clients with the tools to confidently treat genito-pelvic pain and penetration disorders (GPPPD). Addressing the issue from an integrated approach, the book provides evidence-based information and sensate, solo and partner practical exercises derived from the author's experience to help clinicians support women in redefining their relationship with sex, their bodies, and their partners. With a special focus on those from conservative and religious backgrounds, this beautifully illustrated text emphasizes the psychological, emotional, and relational factors that may increase shame and fear surrounding sex. The book defines GPPPD before outlining the author's ABCs approach, awareness, body, control, and safety, where she examines topics such as sexual abuse, how to communicate with you partner, sexual beliefs and messages, the importance of arousal, vulnerability and assertiveness, and shifting the significance of penetration for an enjoyable sex life. This book is essential reading for training and established sex therapists, family therapists, and couple therapists looking to support those struggling with sexual intimacy, as well as the couples seeking their help.