This reference provides contemporary information on all aspects of Down syndrome, investigating health concerns by age group and by organ system. The text sets out to identify and correct problems before they interrupt developing skills. It includes preventive medical checklists with summaries of appropriate medical intervention; supplies background information about history, genetics and epidemiology; outlines clinical management strategies; establishes guidelines on how to inform parents of the diagnosis and conveys practical suggestions on the handling and care of the infant; and offers a detailed review of the medical literature. Appendices provide information including growth charts and financial checklists.

Global Perspectives on Childhood Obesity: Current Status, Consequences and Prevention, Second Edition examines the current childhood obesity epidemic, outlines the consequences of this crisis, and develops strategies to forestall and prevent it. This book provides a thorough investigation of the causes of childhood obesity and, more importantly, offers specific prevention strategies that can be used by medical and mental health professionals, policymakers, community organizers, and individuals. New chapters on BMI and cardiovascular disease, exercise, neurotransmitters, neurocognition, nutrigenomics and combined prevention strategies are included, making this a solid introduction on the childhood obesity crisis. Researchers, practitioners, and advanced students in public health, health policy, and health economics, as well those working in medicine, pharmacy, nutrition, school health, physiology, and neuroscience related to obesity will find this to be a comprehensive resource.

Advances and Techniques in Restoration Therapy focuses on the practical elements of the Restoration Therapy Model to help mental health professionals working with individuals, couples, and families, to restore broken identities and senses of safety, and to move toward action that is functional and healing. Richly illustrated with case examples from experienced clinicians, this volume brings new insights and a range of established and emerging therapeutic techniques to the framework and Restoration Therapy community. This is an innovative and much-needed step-by-step manual, which will provide marriage and family therapists and counselors with practical ways of applying key interventions to varied situations of pain, to help clients find functional, healing solutions with integrity.

This book provides an up to date review on antimicrobials dosing in obese patients, including practice recommendations for clinical use. The book is written by a group of doctors and pharmacists working in infectious diseases practice and research. The introductory chapter outlines the important physiological changes in obesity including factors affecting the dosing of antimicrobials in obese patients. The introductory chapter is followed by ten chapters covering the major classes of antibiotics, antifungals, and antivirals. Each chapter briefly discusses the pharmacokinetics changes related to obesity and a summary of the relevant up-to-date literature. Specific dosing recommendations are provided for each class supplemented by real-life examples as clinical cases that are included as an appendix to the book. The book is a useful resource for clinicians, students and researchers needing up-to-date information on antimicrobial dosing in obese patients. Doctors, pharmacists, nurses working in hospital settings, and students of health courses (medical, pharmacy and nursing students) will find this book particularly useful.

THE COMPLETE PSYCHOTHERAPY TREATMENT PLANNER

Of Related interest

Arthur E. Jongsma, Jr. and L. Mark Peterson

This valuable guide provides a thorough introduction to treatment planning and contains all of the necessary elements for developing formal treatment plans. In an easy-reference, prewritten format, this book presents detailed problem definitions, treatment goals, objectives, therapeutic interventions, and DSM-IVTM diagnoses for over thirty common clinical problems. Practitioners in the field will find this book to be a great time-saver and an invaluable reference.

1995 (0-471-11738-2) 176 pp.

THERASCRIBETM FOR WINDOWS(r)

The Computerized Assistant to Psychotherapy Treatment Planning.

Arthur E. Jongsma, Jr., L. Mark Peterson, and Kenneth Jongsma.

This revolutionary computerized treatment planning software lets you create detailed, customized treatment plans easily and quickly. Designed for use in both inpatient and outpatient settings, its user-friendly format allows clinicians to easily access a wide variety of behavioral definitions, treatment goals and objectives, therapeutic interventions, and DSM-IV diagnoses from its huge database. Its well-organized reports are designed to meet the requirements of Medicare, HMOs, and other third-party payers, which makes this program an important tool for evaluating and treating mental illness.

1997 (0-471-18415-2) 4 3.5 disks

THE COMPLETE GUIDE TO MANAGED BEHAVIORAL HEALTHCARE

Edited by Chris E. Stout and Gerald A. Theis

Managed care has radically altered the mental health services landscape. This loose-leaf style reference manual, which is updated semiannually, offers in-depth analysis from leading experts of changes in practice management, quality and outcome issues, technology, and automation. It also addresses important legal, regulatory, fiscal, and contractual concerns. Packed with practical tools and useful sample forms, the Guide includes a comprehensive glossary of managed care terms and a complete list of managed care organizations.

1996 (0-471-12586-5) 324 pp.

THE MEASUREMENT & MANAGEMENT OF CLINICAL OUTCOMES IN MENTAL HEALTH

Once used almost exclusively by psychotherapy researchers, clinical outcomes testing is quickly becoming a standard component of mental health practice. JCAHO has mandated that outcomes must be included in mental health record keeping by the end of the decade, and the six largest managed care firms have announced plans to begin tracking clinical outcomes. While debates over the potential advantages and disadvantages of this move rage on, the fact remains that all clinicians in managed care systems will soon be compelled to incorporate outcomes assessment into their clinical routines.

The Measurement and Management of Clinical Outcomes in Mental Health prepares clinicians and administrators for this inevitability. Written by a team of experts with extensive experience in design and implementation, this timely book explores the rationale behind outcomes measurement and offers readers concrete advice and guidelines on conducting accurate and effective outcomes measurement.

In the first half of the book, the authors review the conceptual and practical aspects of outcomes management. Among the issues receiving special attention are: the psychometrics of outcomes; measuring patient satisfaction; implementation strategies; the role of consumer characteristics in outcomes management, especially in regard to needs-based planning; case-mix adjustment strategies; and barriers to implementation and strategies for overcoming them.

The second half of the book is devoted entirely to detailed case examples. Over the course of five chapters, the authors vividly illustrate their approaches to outcomes management in five different specialty areas--outpatient psychotherapy, acute psychiatric services, community services, child and adolescent services, and substance-abuse treatment services.

The first comprehensive guide to designing and implementing outcomes evaluation systems, The Measurement and Management of Clinical Outcomes in Mental Health is an important resource for all mental health practitioners as well as mental health and managed care administrators.

Get a quick, expert overview of the many key facets of obesity management with this concise, practical resource by Dr. Jolanta Weaver. Ideal for any health care professional who cares for patients with a weight problem. This easy-to-read reference addresses a wide range of topics - including advice on how to "unpack" the behavioral causes of obesity in order to facilitate change, manage effective communication with patients suffering with weight problems and future directions in obesity medicine. Features a wealth of information on obesity, including hormones and weight problems, co-morbidities in obesity, genetics and the onset of obesity, behavioral aspects and psychosocial approaches to obesity management, energy and metabolism management, and more. Discusses pharmacotherapies and surgical approaches to obesity. Consolidates today's available information and guidance in this timely area into one convenient resource.

This issue of Medical Clinics, Guest Edited by Drs. Scott Kahan and Robert Kushner, is devoted to Obesity. Articles in this outstanding issue include: Obesity as a Disease; Treating Obesity in Primary Care; Obesity Guidelines Overview; Obesity in Special Populations: The Elderly and Aging; Obesity in Special Populations: Young Adults and Adolescents; Obesity in Special Populations: Pregnancy and Peri-pregnancy, Including Epigenetics; Nutrition in Obesity Management: Cornerstones of Lifestyle Management; Physical Activity in Obesity Management: Cornerstones of Lifestyle Management; Behavioral Medicine and Counseling for Obesity; Obesity Pharmacotherapy; Medical Devices for Obesity Treatment; Bariatric Surgery for Obesity; Weight Maintenance and Long Term Management in Obesity; and Case Studies in Obesity Medicine.

There have been many books written on the subject of obesity, but most have approached the topic from the standpoint of the nutritionist, concluding from the somewhat fallacious evidence of changes in body mass that exercise has little place in the prevention or the treatment of obesity. This new volume, written by an exercise physiologist, approaches the topic through a thoughtful lens, suggesting that regular physical activity plays an important role in preventing the development of obesity, is a valuable adjunct therapy in the treatment of the established condition, and makes a solid contribution to the maintenance of weight loss once target weights have been achieved. In addition to detailing evidence that supports such a conclusion, the text offers a unique perspective on obesity over the ages. It evaluates methods of determining body fat content that are appropriate to field and epidemiological studies, and it looks at the timing and aetiology of the recent obesity epidemic. It also considers the diseases associated with obesity and the resultant medical costs, attempting to disentangle the respective contributions of a sedentary lifestyle and the resultant accumulation of fat to the observed patterns of ill-health. Other sections of the text suggest that adipose tissue has important functions beyond the passive storage of energy, and looks critically at the excuse of "bad genes" that some people plead to explain their excessive body weight. Obesity: A Kinesiologist's Perspective should thus provide helpful information and be a key resource for students and researchers alike in bariatrics, kinesiology and nutrition as well as the related disciplines.

Obesity is a rising global health problem. On the one hand a clearly defined medical condition, it is at the same time a corporeal state embedded in the social and cultural perception of fatness, body shape and size. Focusing specifically on the maternal body, contributors to the volume examine how the language and notions of obesity connect with, or stand apart from, wider societal values and moralities to do with the body, fatness, reproduction and what is considered 'natural'. A focus on fatness in the context of human reproduction and motherhood offers instructive insights into the global circulation and authority of biomedical facts on fatness (as 'risky' anti-fit, for example). As with other social and cultural studies critical of health policy discourse, this volume challenges the spontaneous connection being made in scientific and popular understanding between fatness and ill health.

This clinician manual presents the Accept Yourself! Program, which is derived from empirically supported interventions (including Acceptance and Commitment Therapy and Health At Every Size) that have a demonstrated ability to enhance women's mental and physical health. This book offers a clear, research-based, and forgiving explanation for clients' failure to lose weight, helpful guidance for clinicians who are frustrated with poor client weight loss outcomes, as well as a liberating invitation to clients to give up this struggle and find another way to achieve their dreams and goals.

Over the past decade, there have been a large number of important studies related to fluid management for the surgical patient, resulting in confusion on this critical aspect of patient care. Proper fluid therapy in the perioperative setting has always been important but has only recently had concrete outcome-based guidelines. This is the first comprehensive, up-to-date and practical summary book on the topic.

Over the past decade, there have been a large number of important studies related to fluid management for the surgical patient, resulting in confusion on this critical aspect of patient care. Proper fluid therapy in the perioperative setting has always been important but has only recently had concrete outcome-based guidelines. This is the first comprehensive, up-to-date and practical summary book on the topic.

An international team of experts critically review the recent progress in basic and applied research in angiogenesis. Their cutting-edge discussion ranges from the stimulation and repression of angiogenesis to the discovery of novel targets and the use angiotherapy in the clinic. They also detail the fundamental concepts in the physiology and pathophysiology of angiogenesis and evaluate the potential of angiotherapy in the management of angiogenic disease, highlighting some of the angiogenics and antiangiogenics both in development and in clinical trials.

This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.

In the last three decades, the prevalence of obesity has doubled with over 600 million obese adults worldwide. The gastrointestinal complications of obesity are well publicized; however, the role of the gastrointestinal tract in the development and treatment of obesity is often understated. From the pathophysiologic role of gut hormones and the microbiota, to the purposeful, anatomic derangement of the gastrointestinal tract that is utilized as a treatment for obesity, it is imperative that gastroenterologists understand the full scope of obesity in relation to the gastrointestinal system. Studies suggest that in the U.S. obesity is underrecognized and undertreated by health care providers. Given its complex sociology, pathophysiology, and treatment, obesity, like many other diseases, requires a multidisciplinary approach. Therefore, gastroenterologists must be equipped with the relevant knowledge of obesity that will empower them to properly manage their patients.

Since time immemorial Man has pursued the elusive elixir of life. The wisdom of ancient Chinese medicine declared immortality unattainable, but offered the elixir of longevity through lifestyle, diet, the judicious use of herbal tonics and the practice of subtle but powerful exercises of qigong and taijiquan.This concise volume explains in modern scientific language the principles of ancient Chinese methods of health and the practice of yangsheng or life cultivation. Natural holistic solutions to health issues and the intricacies of Chinese diagnosis and therapies are brilliantly exposed, complete with detailed descriptions of herbs, acupuncture and tuina.Discover appetizing recipes for soups, porridges and teas that give you that healthy glow and nourish your body and soul. Based on a series of popular lectures by the authors, this book opens a new chapter in your pursuit of a long and fulfilling life. It is also excellent preparation for more advanced studies in Chinese medicine.

Since time immemorial Man has pursued the elusive elixir of life. The wisdom of ancient Chinese medicine declared immortality unattainable, but offered the elixir of longevity through lifestyle, diet, the judicious use of herbal tonics and the practice of subtle but powerful exercises of qigong and taijiquan.This concise volume explains in modern scientific language the principles of ancient Chinese methods of health and the practice of yangsheng or life cultivation. Natural holistic solutions to health issues and the intricacies of Chinese diagnosis and therapies are brilliantly exposed, complete with detailed descriptions of herbs, acupuncture and tuina.Discover appetizing recipes for soups, porridges and teas that give you that healthy glow and nourish your body and soul. Based on a series of popular lectures by the authors, this book opens a new chapter in your pursuit of a long and fulfilling life. It is also excellent preparation for more advanced studies in Chinese medicine.

The Nocebo Effect documents the transformation of normal problems into medical ones and brings out the risks of this inflationary practice. One notable risk is that people labeled as sick may find themselves living up to their label through the alchemy of the nocebo effect.

This issue of Primary Care: Clinics in Office Practice, devoted to Obesity Management, is guest edited by Dr. Mark Stephens of the Uniformed Services University of the Health Sciences in Bethesda, Maryland. Articles in this important issue include: Obesity: What Do the Statistics Say?; Economic Impact of Obesity; The Future of Pediatric Obesity; Obesity Prevention and Screening; Behavior Modification in Obesity Management; Nutritional Therapy; Physical Activity: Cornerstone or Roadblock?; Pharmacologic Therapy for Obesity; Surgical Approaches to Obesity; Multidisciplinary Teams and Obesity: Role of the Modern Patient Centered Medical Home (PCMH); Healthcare Systems and National Policy: Role of Leadership in the Obesity Crisis; and Special Populations in Obesity Management.

Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs.

First Published in 1978. Routledge is an imprint of Taylor & Francis, an informa company.

The intent of the book is to provide readers with a summary of the obesity problem with specific focus on the metabolic health issues (ie, diabetes mellitus), obstructive sleep apnea, non-alcoholic fatty liver disease and the psychological effects of obesity. This will provide readers with an understanding of the commonly performed operations for obesity along with evidence-based outcomes, nutritional issues, and metabolic consequences.

First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.

This volume examines the biocultural dimensions of obesity from an anthropological perspective in an effort to broaden understanding of a growing public health concern. The United States of America currently has the highest rates of obesity among developed countries, with an alarming rise in prevalence in recent decades which promises to affect the nation for years to come. Bellisari helps students to grasp the complex nature of this obesity epidemic, demonstrating that it is the consequence of many interacting forces which range from individual genetic and physiological predispositions to national policies and American cultural beliefs and practices. As much a social problem as an individual one, the development of obesity is in fact encouraged by the pattern of high consumption and physical inactivity that is promoted by American economic, political, and ideological systems. With a range of up-to-date scientific and medical data, The Anthropology of Obesity in the United States provides students with a comprehensive picture of obesity, its multiple causes, and the need for society-wide action to address the issue.

Together, obesity and diabetes form a 21st century epidemic, the treatment of which consumes a substantial fraction of global health costs. New and improved therapies are therefore desperately needed.Incretins are short peptide hormones released from the gut in response to food transit. These hormones regulate a plethora of processes to control food intake, body weight and glucose homeostasis. This is one of the fastest areas of growth within diabetes research, and over the past decade, increasing numbers of novel diabetes drugs - many based on incretin action - have been added to the therapeutic armoury.Following an introduction detailing the historical perspective and discovery of incretin therapies and clinical applications, the book looks at the release of incretins at a cellular level from entero-endocrine cells, and actions on the pancreas (alpha and beta cells) and brain. It then looks at changes in incretins seen in diabetes and following bariatric surgery. Finally, the side effects of incretin therapy are discussed. Importantly, each chapter contains a methodology section aimed at providing a practical guide to key techniques in the field of incretin biology and ranges from basic laboratory research to clinical practice.Incretin Biology - A Practical Guide offers a unique perspective within this field of research by bringing together scientists, physicians and bariatric surgeons. Thus, it is a comprehensive text that offers a broad overview of the subject.