After training as an apothecary and surgeon, Jonathan Pereira (1804-53) taught materia medica for many years. His lectures at the medical school in London's Aldersgate Street were highly successful and formed the basis for the first edition of his major encyclopaedic work on medicinal substances. A pioneering text in the field of pharmacology, Pereira's work, which he subsequently updated in further editions, provided pharmacists and medical professionals with a more rigorous scientific understanding of the drugs and remedies they prescribed. After Pereira's death, medical jurist Alfred Swaine Taylor (1806-80) and physician George Owen Rees (1813-89) prepared this revised and expanded fourth edition, interspersed with instructive woodcuts. Volume 1 (1854) includes discussion of 'physical remedies' such as heat, cold and electricity, and 'hygienic remedies' of diet, exercise and climate. It then focuses on general pharmacological practice and specific drugs, describing the medicinal properties of inorganic compounds.

After training as an apothecary and surgeon, Jonathan Pereira (1804-53) taught materia medica for many years. His lectures at the medical school in London's Aldersgate Street were highly successful and formed the basis for the first edition of his major encyclopaedic work on medicinal substances. A pioneering text in the field of pharmacology, Pereira's work, which he subsequently updated in further editions, provided pharmacists and medical professionals with a more rigorous scientific understanding of the drugs and remedies they prescribed. After Pereira's death, medical jurist Alfred Swaine Taylor (1806-80) and physician George Owen Rees (1813-89) prepared this revised and expanded fourth edition, interspersed with instructive woodcuts. Volume 2 is divided into two parts. Part 2 (1857) contains new articles, additional illustrations and a separate index. It concludes the analysis of organic compounds, both vegetable and animal.

This is a concise and timely review, which discusses the background of obesity, preventative care, medical and surgical treatment options, and long-term support for patients with obesity. Busy healthcare professionals who want a rapid review of obesity as well as a summary of the most recently approved surgical devices and medical therapies will benefit from this succinct guide.

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

This volume thoroughly examines breast cancer stem cells (BCSCs), from basic definitions to techniques for identifying, isolating, culturing, and targeting BCSCs for therapy; there is additional focus on pre-clinical and clinical results. The text begins with a discussion of breast cancer, focusing especially on the limitations of current therapies in its treatment. The subsequent chapters introduce and compare stem cells and cancer stem cells, describe properties and isolation techniques of BCSCs, and examine BCSC-targeting approaches. The text concludes with a discussion of controversy surrounding the BCSC hypothesis and of future research directions. Breast Cancer Stem Cells & Therapy Resistance, part of the SpringerBriefs in Stem Cells series, provides a succinct yet comprehensive overview of BCSCs for advanced students, graduate students and researchers as well as those working with breast cancer or stem cells in a clinical setting.

In 1986 the first research study investigating Acceptance and Commitment Therapy (ACT) was published. It aimed to determine if an early conceptualization of the ACT model could be used to treat depression. Since this seminal study, further investigations have been conducted across every imaginable psychological issue and the rate at which this research has emerged is impressive. This book describes the research journey that ACT has taken in the past 30 years. It also suggests, in light of the progress that has already been made, how ACT research should move forward in the coming decades.

In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn's disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population's phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Newly updated and revised, Physical Therapy Documentation: From Examination to Outcome, Third Edition provides physical therapy students, educators, and clinicians with essential information on documentation for contemporary physical therapy practice. Complete and accurate documentation is one of the most essential skills for physical therapists. In this text, authors Mia L. Erickson, Rebecca McKnight, and Ralph Utzman teach the knowledge and skills necessary for correct documentation of physical therapy services, provide guidance for readers in their ethical responsibility to quality record-keeping, and deliver the mechanics of note writing in a friendly, approachable tone. Featuring the most up-to-date information on proper documentation and using the International Classification of Functioning, Disabilities, and Health (ICF) model as a foundation for terminology, the Third Edition includes expanded examples across a variety of practice settings as well as new chapters on: Health informatics Electronic medical records Rules governing paper and electronic records Billing, coding, and outcomes measures Instructors in educational settings can visit www.efacultylounge.com for additional materials to be used for teaching in the classroom. An invaluable reference in keeping with basic documentation structure, Physical Therapy Documentation: From Examination to Outcome, Third Edition is a necessity for both new and seasoned physical therapy practitioners.

Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing prevalence and incidence in the last two decades. This book, edited by two experienced surgeons and a clinical psychologist in cooperation with numerous worldwide leading experts, presents clinically relevant information for gastroenterologists, internists, surgeons, residents and also nurses, who frequently care for GERD patients. Focusing on different treatment concepts - medical, endoscopic as well as surgical - the chapters include the basics of symptomatology and epidemiology, pathophysiology, GERD among different age groups, complications and its treatment, hiatal hernia or H. pylori and GERD, NERD and functional heartburn, diagnostic procedures and also presurgical examination. In addition, the patient's perspectives of disease, diagnostics and treatment are included, the same as economic aspects of GERD, and the impact of disease on quality of life or patient-reported outcomes after treatment.

As a result of the rapidly growing rate of obesity worldwide, clinicians are struggling to provide the best strategies for treating obese patients with concomitant pulmonary conditions. Obesity does not simply change the epidemiology of pulmonary disease; obesity has a profound impact on the pathophysiology of common pulmonary diseases. Obesity affects the severity of asthma, response to treatment, and is likely a major modifier of the phenotype of asthma. Obesity also appears to affect response to pathogens, and as such has a major influence on response to pneumonia, and has a significant impact on outcomes pertaining to acute lung injury in the intensive care unit. Obesity and Lung Disease: A Guide to Management is the first text in the field to cover the full range of issues related to managing obese patients with pulmonary problems. All the relevant conditions, in the context of obesity, are covered, including airway inflammation, sleep apnea, asthma, pulmonary hypertension, obesity hypoventilation, as well as others. Written by an international group of experts, this important new volume is an invaluable resource for all clinicians and scientists concerned with the challenging problems surrounding obesity and lung diseases.

With an increasing number of referrals to treat balance impairment, gait disorders, and dizziness, A Clinician's Guide to Balance and Dizziness: Evaluation and Treatment by Dr. Charles M. Plishka looks to address these issues and provides tests, measures, and interventions that are matched to research studies when available, for evidence-based practice. It begins with a review of the anatomy and physiology of the systems used to balance. With a basic understanding of how we balance, the signs and symptoms of patients will be understood with much greater ease. A Clinician's Guide to Balance and Dizziness enables the reader to perform a complete and thorough evaluation and helps to provide treatment options for identified deficits that place the patient at risk for falls. Along with numerous diagrams and photos, this text comes with access to a web site containing video clips that demonstrate key evaluation and treatment techniques. The result will be a better evaluation, treatment plan, and outcome. Topics and Features Include: How do we balance? Tests to evaluate the balance-impaired patient Tests and interventions for conditions such as Benign Paroxysmal Positional Vertigo (BPPV), Vestibular Loss, and the central and peripheral causes of dizziness Therapy treatments "How to" instructions throughout Companion web site with video clips demonstrating evaluation and treatments A Clinician's Guide to Balance and Dizziness: Evaluation and Treatment is an easy-to-use reference perfect for professionals who assess and treat balance impairments and dizziness. While it is an instructional text for physical therapy students and clinicians, it is also a great reference for established physicians, vestibular and balance therapy specialists, occupational therapists, nurse practitioners, physician assistants, audiologists, and athletic trainers.

Long-term oxygen therapy (LTOT) usually represents the final step in the management of severe chronic respiratory diseases: a large proportion of patients suffering from these conditions is involved and the corresponding impact for the Health Institutions and the Society is dramatically increasing. Although LTOT is well known and widely used since long ago in most modern countries, it still represents a challenging topic due to the huge amount of variables which can affect both its efficacy and effectiveness. Unfortunately, patients, doctors, care-givers, together with health institutions and political decision makers frequently have different visions on LTOT, thus highly contributing to obtain uneven results and changing outcomes. The focus of this volume is on new insights and novel perspectives of LTOT. Starting from consolidated experiences, it's aim is also to emphasize the strategic value of developing technologies and innovative organizational models uniquely to find out even more opportunities and advantages for the management of chronic respiratory patients needing long-term oxygen treatment.

This title includes a number of Open Access chapters. Child obesity is a serious condition that affects children around the world in growing numbers. With obesity comes an increased risk of other chronic diseases as well, making it even more important to understand and treat this condition from a variety of angles. This current volume seeks to understand the phenomenon of child obesity and presents a range of viewpoints on its prevalence, causes, and treatments. The different sections contained within explore the following topics: * The worldwide prevalence of childhood obesity and its growing effect on children * The causes of childhood obesity and the complex interactions of genetic, environmental, social, and medical factors that contribute to its development * Proposed treatments, some intervention-based and others that aim to change how food is marketed and sold to youth This reference volume offers a comprehensive and thorough guide to a field that is rapidly expanding and points to new directions in research and public policy. Edited by a doctor with extensive experience as a researcher, writer, and medical practitioner, The Childhood Obesity Epidemic is an authoritative and easy-to-use reference that provides resources for researchers in the field, students, and anyone who wishes to gain an overview to this important field of study.

This title includes a number of Open Access chapters. Childhood obesity is a major public health crisis nationally and internationally. This insightful compendium provides valuable information and assesses the research foundations behind several school initiatives to help combat the epidemic of obesity in children and adolescents, particularly using interventions to increase physical activity. The book looks at the issue from three levels: first, the effects of unhealthy eating and lack of exercise on a number of health outcomes in children and adolescents; second, successful small- and large-scale school-based interventions; and finally, synthesis of current literature and translation into specific guidelines and recommendations. Specific topics addressed in the book include: * The appeal and benefits of outdoor versus indoor activity * Cultural differences in physical activity * Successful interventions and their continued success, or lack of, after several years * The roles of family and community interventions * Staff involvement in children's physical activities * Specific programs, such as Plant Health, an antismoking intervention with unintended obesity intervention * Establishing healthy habits in youth This research provides schools with a strong foundation for implementing policies and practices that support healthy eating and regular physical activity. In the process, educators will be ensuring the best possible chance for increasing students' academic success, improving both physical and mental health, and decreasing the risk for myriad chronic diseases.

Why is music so important to most of us? How does music help us both in our everyday lives, and in the more specialist context of music therapy? This book suggests a new way of approaching these topical questions, drawing from Ansdell's long experience as a music therapist, and from the latest thinking on music in everyday life. Vibrant and moving examples from music therapy situations are twinned with the stories of 'ordinary' people who describe how music helps them within their everyday lives. Together this complementary material leads Ansdell to present a new interdisciplinary framework showing how musical experiences can help all of us build and negotiate identities, make intimate non-verbal relationships, belong together in community, and find moments of transcendence and meaning. How Music Helps is not just a book about music therapy. It has the more ambitious aim to promote (from a music therapist's perspective) a better understanding of 'music and change' in our personal and social life. Ansdell's theoretical synthesis links the tradition of Nordoff-Robbins music therapy and its recent developments in Community Music Therapy to contemporary music sociology and music studies. This book will be relevant to practitioners, academics, and researchers looking for a broad-based theoretical perspective to guide further study and policy in music, well-being, and health.

A dramatic and worldwide increase is occurring in the prevalence of overweight and obesity in women of childbearing age. Obese women carry a significant excess risk of a variety of serious complications during pregnancy, and in addition, maternal obesity predisposes to obesity in the offspring. This book provides a timely update on the latest knowledge on maternal obesity and pregnancy. A very wide range of issues are covered, including macrosomia and associated shoulder dystocia; the risk of miscarriage, malformations, and complications of pregnancy; the impact of hyperglycemia; clinical management; consequences for anesthesia and ultrasound; impacts on breastfeeding, fertility, and childhood obesity; and pregnancy following gastric surgery. All of the authors are recognized experts in their fields, and the book has been designed to meet the practical needs of obstetricians, gynecologists, internists, and general practitioners.

This 1983 book reports the proceedings of the eleventh European symposium on clinical pharmacy which was held in Brussels in October 1982. The theme of the symposium was the concept of the therapeutic team and the relative contributions and responsibilities of pharmacists, nurses and physicians to the planning and implementation of drug treatment regimens. The first section of the volume provides an introduction to the concept of the therapeutic team and reflects the views several medical professionals. The later sections cover the practice of the therapeutic team in parenteral nutrition, oncology, dermatology, epilepsy, internal medicine, nuclear medicine and drug selection. Not only did this book review achievements and experiences in clinical pharmacy, but it also looked towards the future of clinical pharmacy development in Europe. It will still be of significant interest to clinical pharmacy specialists today.

This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.

Bioelectromagnetic and Subtle Energy Medicine focuses on a wide variety of evidence-based bioelectromagnetic and subtle energy therapies for disorders ranging from cancer, cardiomyopathy, and Parkinson's disease to depression, anxiety, and pain. Since publication of the first edition more than a decade ago, there have been so many advances in these and other diseases, that a thorough revision is required for this resource to remain the gold standard in a burgeoning field. This second edition updates previous topics and features many new chapters describing novel approaches that promise to replace drugs or surgery because they are more effective and much safer, such as rTMS for depression, MRI-Guided Focused Ultrasound for bone and uterine tumors, and TheraBionic LEET for liver cancer. Others discuss biological water (H3O2) that acts like a battery, health benefits of Earthing, malignant and other brain tumors from cell and cordless phones, visualizing and measuring energy fields in humans and nature, making sense of homeopathy and "memory of water," basic science support for acupuncture, electrosensitivity, ion cyclotron resonance, the role of the pineal gland, the health effects of solar storms and terrestrial influences, and why Bioelectric Resonance Therapy bridges Chinese and Western medicine. This is only a sampling of the 50 chapters contributed by authorities from the United States, Europe, Scandinavia, Russia, China, Japan, and Iran.

This book explores the pathophysiology, clinical assessment and management of the obese patient in the context of serious chronic disease, as well as the political and environmental aspects, including prevention. The book's approach of arriving at an exploration of these issues through the vehicle of assessing the controversies is unique and interesting, attempting to debunk the myths and explore the genuine science whilst demonstrating areas where healthy debate is rife.

Obesity During Pregnancy in Clinical Practice highlights the medical evidence on obesity in the postpartum and interconception period, arming clinicians with the knowledge necessary to communicate with their patients on the effect of these changes on diabetes, cardio vascular disease and certain cancers. Obesity During Pregnancy in Clinical Practice provides concise and understandable summaries of the evidence-based, theory-driven lifestyle interventions that have been shown to be effective for weight loss and modifying the risk of developing diabetes and obesity.

Regain Be Gone is the only resource readers need to help them keep weight regain at bay after bariatric surgery. With 20 years of training in the field of bariatrics, trusted dietitian Sameera Khan shares strategies toward a balanced, stress-free weight-loss journey so that readers can feel confident, powerful, and successful. Weight regain is a manageable setback that can be reversed with a little effort and guidance. The longer one ignores it, the harder it is to regain lost ground, so act now. Regain Be Gone is the only resource people need to help them keep weight regain at bay after bariatric surgery.

The aim of this book is to provide clear and concise information about the safe prescribing of insulin both subcutaneously and intravenously. It provides information on the different types of insulin, the delivery devices, side effects of insulin and, most importantly, on rational dose adjustment.

Cardiopulmonary Physical Therapy: Management and Case Studies, Second Edition is a unique and succinct textbook for the classroom that blends clinical notes on assessment and management together with case-based instructional approaches to cardiopulmonary care for acute and ambulatory care patients. This one-of-a-kind text describes current approaches that cover traditional physical therapist management strategies and includes evidence-based chapters on early mobilisation and exercise training on a wide range of cardiopulmonary patient groups. The updated Second Edition presents twenty-four cases that were designed to complement each chapter topic and represent the most common pulmonary, cardiac, and neurological conditions that are typically managed in cardiopulmonary care. These cases have been carefully selected and developed over several years to illustrate a spectrum of clinical issues essential for the preparation of the entry-level therapist. The very interactive nature of the case history approach is engaging and provides the opportunity to work through many of the steps of the clinical decision-making process. Cardiopulmonary Physical Therapy: Management and Case Studies, Second Edition also includes answer guides for the questions posed in the assessment and management chapters, as well as for the twenty-four cases. New in the Second Edition: Twenty-four carefully selected evidence-based cases designed to go "hand-in-hand" with chapter topics An international perspective that is relevant to physical therapy practice in several countriesDetailed chapter on non-invasive ventilation and mechanical ventilationSeveral chapters describe early mobilisation and exercise training for a range of cardiopulmonary patient groups including those admitted to an intensive care unitFaculty will benefit from the "Talk Me Through" PowerPoint slides, which provide a great opportunity for independent learning and complement classroom teaching The two-fold evidence and case-based learning approach used by Dr. W. Darlene Reid, Frank Chung, and Dr. Kylie Hill allows for a more engaging experience. The inclusion of interactive materials will allow students to learn and develop skills to prepare themselves for their professional transition while clinicians can use the text as a reference tool.