Much more than an archive, these are the vivid, still pertinent voices and messages of the pioneers worldwide. The nineteen articles chosen by the editors of Applied Theatre Research represent key themes and elements from the early days of applied theatre that are still - and indeed now more than ever - relevant. They are all high-quality articles, some of which were highly influential in their own time. All of them still have plenty to say to today's applied theatre, both in their own terms and sometimes in terms of how their publication influenced the development at the time of this still-expanding field, or refracted it in ways that give us new insights with hindsight. They have been arranged in sections according to some of the key themes - and problematic issues - that were discovered, thought out and sometimes stumbled across by the pioneer writers in the collection. Each section is preceded by a critical editorial commentary on those themes, besides thorough introductions to all the articles and in some cases re-evaluations. The editors have added substantial additional new material to the collection and in doing so, bring their own applied theatre experience to bear on these themes, as they raise general questions that are wide-ranging, contemporary and urgent: from the vital and contested issues of power, partnerships and the giving of voice through theatre to applied theatre's proactive response to COVID-19, to the need to identify, take account of and address the needs of all stakeholders in any applied theatre project. The articles are grouped in six sections, covering areas such as diversity of geography, community contexts, forms of applied theatre and organizational factors that characterize applied theatre; the definition and nature of applied theatre; how the best intentioned projects could be compromised by any of the many opportunities for applied theatre to go wrong; opportunities for change it can offer and the incorporation of new media technologies, and ethnographic performance, two factors that have now become major preoccupations for our field, particularly in the years since the articles were written. The final section recognizes that applied theatre has been around not for 30 years, but for thousands, and in countless cultures. The editorial chapters have strong connections with the rest of the book, but are written with the editors' deep insights into the field, and are sharp in their focus and context. The book offers useful insights into the start of applied theatre and its development as an area of practice and research. The chapter collection is relevant and includes influential names in the field who have contributed significantly to the development of applied theatre over time. The primary market will be academics and advanced practitioners in applied theatre, drama education and theatre studies - including the expanding fields of drama therapy, theatre and health etc. It will also be useful for educators exploring creative pedagogy and drama in education strategies across the curriculum. It will be valuable introductory background reading for advanced undergraduate and post-graduate students in drama, theatre studies and theatre arts, performance studies and community theatre.

Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-dependent activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. By providing a broader view of signaling bias, this resource helps to explain common mechanisms shared across receptor classes and how this can be utilized to elucidate their cellular activity and better understand their therapeutic potential. Written for both new and established scientists in pharmacology, cell biology, biochemistry, and signal transduction, as well as physicians, this book clearly illustrates how biased receptor signaling can be utilized to develop and understand complex pharmacology. Chapters are each focused on a specific class of receptor or other important topic and make use of real-world examples illustrating how the latest research in signal transduction has led to a better understanding of pharmacology and cell biology. This structure creates a basis for understanding that physiological signalling bias has been selected by nature in order to provide complex and tissue- specific biological responses in the face of limited receptors and signaling pathways. This book provides a framework to reveal that these physiological mechanisms are not restricted to one receptor type or family and thus presents receptor signaling from a newer, more global perspective.

This new book summarizes the adherence literature for a number of specific health behaviors and populations. It provides a comprehensive source on the conceptualization, interventions, and measurement of treatment adherence and a synthesis of the research across demographic and chronic diseases. The text presents problems associated with treatment adherence; theoretical models that have commonly been used to understand, predict, and/or improve adherence; adherence with specific behaviors including exercise, diet, rehabilitation, medication, and psychological therapies; and strategies in enhancing adherence. Because chronic diseases involve similar behaviors, the handbook is organized by specific behaviors and special populations, and not by disease. Every chapter is sub-organized by specific diseases to ensure easy access for the readers and features a discussion of adherence across demographic and chronic conditions, a review of previous interventions directed at the particular behavior or population, questions and scoring algorithms for widely used measures of treatment adherence, a discussion of the clinical research, and where appropriate, policy implications. Patient Treatment Adherence addresses: practical recommendations to improve adherence; the impact of non-adherence including costs and health-related quality of life; methodological issues such as assessing cost-effectiveness; and the use of technological advances to improve adherence. Intended for health service professionals, health, clinical, social, and cognitive psychologists, primary care physicians, pharmacists, and policy-makers, this text is also an excellent resource for graduate courses on health psychology and public health.

The book focuses on two concurrent experimental therapies in cancer treatment known as boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT) using a variety of boron- and gadolinium-based compounds. Some of the gadolinium compounds serve the dual purpose as being MRI contrast agents and GdNCT agents. The book describes why BNCT & GdNCT were not at the forefront of the clinical trials during the past seven to eight decades since the discovery of neutrons by John Chadwick in 1932 and how the latest development in the synthesis of target boron- and gadolinium-based drugs have turned the area to be the hottest one and worthy of further investigation with the new clinical trials in the USA and elsewhere.

The prevalence of obesity in the United States and the rest of the industrialized world has skyrocketed in the past 20 years. Linked to heart disease, diabetes, hypertension, and metabolic syndrome, it is also the leading cause of osteoarthritis and the second leading cause of cancer. With contributions from leading experts in the field, Obesity: Prevention and Treatment bridges the gap between emerging understanding of the pathophysiology of obesity with concrete clinical applications for physicians and other healthcare workers in all disciplines of medicine. Following an overview of issues related to the prevention and management of obesity, the book discusses: Energy balance, the metabolic predictors of weight gain, and the role of adipokines, genetics, and the environment on obesity The epidemiology of obesity The identification and evaluation of the overweight patient as a guide to the selection of treatment Nutritional aspects of obesity treatment and management Exercise risks to which the obese patient may be more prone and steps that can be taken to mitigate these risks Behavior modification strategies for the obese patient The definition, assessment, consequences, and treatment of childhood obesity Drugs and surgical options for treatment The implications of public policy on the problem of obesity The significance of intra-abdominal and ectopic fat deposition in endocrine aspects of obesity Currently, over two thirds of the adult population in the United States is either overweight or obese. With these grim statistics, it is critically important that clinicians from all branches of medicine play an active role in diagnosing and treating obesity and its related conditions. This volume arms clinicians with the information they need to create an appropriate prevention and treatment program for their patients.

Kidney disease is a global health concern that affects people of all ages and races. Based on the work of the National Kidney Foundation and the Kidney Disease: Improving Global Outcomes foundation, guidelines have been developed outlining the parameters for patient care. Nutritional Therapy for Chronic Kidney Disease builds upon the discoveries made by these institutions and expands upon their recommendations to provide a comprehensive guidebook with practice protocols for individuals with kidney disease. With chapters written by expert authors drawing on their own experiences, the book: Outlines the history of kidney disease and its treatment Details the distinctions in nutrition therapy throughout the five stages of chronic kidney disease Features precise recommendations for management of the complicated renal diet in acute kidney disease Examines dietary concerns for pregnant women, children, persons with diabetes, and post-transplant patients Discusses the common metabolic pathologies associated with kidney disease, including electrolyte and acid-based disorders, bone and mineral disorders, and chronic anemia Includes chapters on obesity and physical activity, quality of life improvement in chronic kidney disease, and dietary counseling strategies Reflecting the medical community's emphasis on patient-centered care, this volume provides a complete primer on the importance of diet in maintaining kidney health and provides practical guidance to caregivers charged with devising nutritional strategies for kidney patients.

Bariatric surgery plays an important role in the treatment of obesity; in this comprehensive resource the worldwide leaders of the field provide the most up-to-date information on the psychosocial issues that affect their patients. Included is an overview and history of surgical procedures, complete with illustrations, practical advice on topics such as physical activity and nutritional care after surgery, and essential information that allows clinicians to assist their clients as much as possible; for example, how pre-weight loss surgery psychosocial evaluations can serve as clinical interventions in their own right, and how structured interviews and questionnaires can be used in multiple contexts such as screening, treatment planning, and prognostic assessment. A distinctive chapter includes an overview of the special issues present in treating adolescents, who increasingly are the target of bariatric surgery procedures. This book is an essential reference for clinicians from the evaluation through the follow-up and aftercare of bariatric surgery patients.

The beautiful new edition of this highly successful book, written by Ann and Chris Frederick, directors of the Stretch to Win(R) Institute, is packed with theory and practice, including a host of beautifully illustrated assisted stretches. Fascial Stretch Therapy(TM), Second edition is a practical and highly applicable manual for any massage therapist, movement instructor, physical or occupational therapist, athletic or sports trainer, fitness instructor or osteopath - in fact for any hands-on practitioners who wants to learn new skills and improve therapeutic outcomes. It clearly demonstrates how FST(TM) assessment, treatment, and training are used in a variety of common circumstances encountered in manual therapy and athletic training. What's new for the second edition... Discusses a very brief history of a still expanding and evolving new industry of assisted stretching. It also covers the negative aspects of this trend, including the lack of assessments and specificity and common stretching methods. Approaches are listed so you can compare and contrast. Includes a new Chapter 2 with updates of the highest quality evidence-based research useful to the field of assisted stretching. It includes the authors' own research about the effects of FST(TM) on chronic nonspecific low back pain as well as a discussion about a recent systematic review of the acute effects of muscle stretching on physical performance range of motion, and injury incidence in healthy active individuals. Lists contraindications and indications for FST(TM) along with new updates to reflect current understandings (e.g. about Golgi tendon organs) with supporting references. Shows how this method will save you time when forming a working hypothesis that will quickly be proven or disproven so that you will have enough time to develop other hypotheses that you can test for efficacy, all within a single session. Includes new photographs and artwork along with new titles to reflect the change in nomenclature from the use of the term 'fascial line(s)' to 'fascial net(s)'.

This first comprehensive guide to the novel field of gene therapy in the skin provides insight into the basic principles and methods of gene transfer into the skin and its applications. It enables the understanding of possibilities and implications such as immunization and treatment as well as safety aspects. Gene therapy in dermatology is the avantgarde of a new field in science with a great future for human health.

In the historical record there is abundant evidence that obesity was a medical and health concern as long as medicine has been practiced. The idea of diet and exercise are bulwarks in the fight against obesity in history from the time of Hippocrates to the 16th century--a span of 2,000 years. However, our scientific understanding of this problem is only a little over 200 years old. An examination of the root cause of what many consider the obesity epidemic, A Guide to Obesity and the Metabolic Syndrome traces the origins and types of obesity and its treatment. Examining in detail the developing treatment for obesity, this book provides: * A history of obesity, including treatment, proposed causes, and perceptions * An examination of the causes and problems associated with obesity * A discussion of lifestyle, diet, exercise, and treatment strategies * A detailed look at the medications and surgeries available for obesity The fact that we have an epidemic of obesity today that is covering the globe suggests that the strategically simple ideas of eating less and exercising more, ideas that require commitment and personal involvement by the individual, have not been very successful. As we move forward in trying to understand this problem, we need to be alert to strategies and tactics that may not require individual motivation and commitment--history has shown that they do not work well. This book supplies guidance on developing and designing novel strategic interventions against obesity and metabolic disorders.

Originally published in 1991, this book covers a comprehensive range of the applications of hypnotic techniques in therapy for psychological disorders, and medical conditions where such techniques are a valuable adjunct. In the years before publication psychologists, medical doctors, dentists and allied professional workers had come to make increasing use of hypnosis in their work, and there was a considerable amount of relevant research literature available in journals. Such literature is reviewed, and served as a practical guide for professionals at the time. The book begins by explaining what is meant by hypnosis today, and traces its historical background. Some fundamental questions such as individual differences in susceptibility to hypnosis are discussed in relation to therapy. Separate chapters are devoted to the key topics of behaviour therapy, different forms of psychotherapy, psychosomatic medicine, the treatment of pain, and applications in medical and surgical procedures. The modern status of hypnotic techniques in obstetrics and in dentistry is reviewed, and a separate chapter on the use of hypnosis with children will be of special interest to educational and clinical psychologists. A final chapter reviews the use of hypnosis by various professions and para-medical disciplines, and discusses the possible abuses that may arise both through unqualified people seeking to practise "hypnotherapy", and by professionals acting outside their proper range of competence.

This issue of Critical Care Clinics, Guest Edited by Marilyn Haupt and Mary Reed will include articles such as: Special Populations; Obesity Paradox; Airway Management; Trauma in the Morbidly Obese; Procedures in the Morbidly Obese Critically Ill.

Topics include: The Obesity Epidemic, Altered Resting and Exercise Respiratory Physiology in Obesity, Association of Asthma and Other Obstructive Lung Diseases and Obesity, Role of Obesity in Obstructive Sleep Apnea, The Pickwickian Syndrome - Obesity Hypoventilation Syndrome, Obesity and Thromboembolic Disease, Medical Therapy of Obesity, Obesity and Bariatric Surgery, Airway Management of Patients with Obesity, Anesthetic Management of Patients with Obesity, Obesity and Acute Lung Injury, Obese Patients in the Intensive Care Units, Obesity Cardiomyopathy, Obesity and Respiratory Diseases in Childhood, Obesity and Respiratory Diseases in the Aging Population.

In this comprehensive and insightful work, Dr. Sharon K. Farber provides an invaluable resource for the mental health professional who is struggling to understand self-harm and its origins. Using attachment theory to explain how addictive connections to pain and suffering develop, she discusses various kinds and functions of self-harm behavior. From eating disorders to body modifications such as tattooing, Dr. Farber explores the language of self-harm, and the translation of that language and its psychic functions in the therapeutic setting. She tells us, 'When the body weeps tears of blood, we need to wonder what terrible sorrows cannot be spoken.' Brilliantly illustrated with rich clinical material, this book offers a practical approach to the diagnosis, assessment, and treatment of the increasing number of patients whose emotions are expressed through bodily harm. The challenges of working with patients who tend to view the world of relationships in terms of predator and prey are clearly explicated and the stormy countertransference responses that threaten to destroy the treatment are given a full hearing. Finally, she shows how the attachment relationship formed in treatment can repair the traumatic attachment in mind, body, psyche, and soul, and can serve as the cornerstone of therapeutic change. A Jason Aronson Book

"This excellent book contains many different scripts, applicable to a number of special populations. It takes a practical approach and walks therapists step-by-step through the EMDR therapeutic process. Readers] will not be disappointed." Score: 93, 4 stars --"Doody's"

Praise from a practicing EMDR therapist and user of Eye Movement Desensitization and Reprocessing (EMDR) Scripted Protocols: "Kudos to...everyone who contributed to this important volume.... It] is an indispensable resource. Thank you, thank you, thank you " --Andrea B. Goldberg, LCSW EMDRIA Certified EMDR Therapist EMDRIA Consultant-in-training Bloomfield and Newark, NJ

This book serves as a one-stop resource where therapists can access a wide range of word-for-word scripted protocols for EMDR practice, including the past, present, and future templates. These scripts are conveniently outlined in an easy-to-use, manual style template for therapists, allowing them to have a reliable, consistent form and procedure when using EMDR with clients.

The book contains an entire section on the development of resources and on clinician self-care. There is a self-awareness questionnaire to assist clinicians in identifying potential problems that often arise in treatment, allowing for strategies to deal with them. Also included are helpful past memory, current triggers and future template worksheet scripts.

Key topics include: Client history taking that will inform the treatment process of patients Resource development to help clients identify and target their problems to regain control when issues appear overwhelming Scripts for the 6 basic EMDR Protocols for traumatic events, current anxieties and behaviors, recent traumatic events, phobias, excessive grief, and illness and somatic disorders Early intervention procedures for man-made and natural catastrophes EMDR and early interventions for groups, including work with children, adolescents, and adults Written workbook format for individual or group EMDR EMDR to enhance performance and positive emotion

The prevalence of obesity has increased markedly in recent years, and obesity is now considered an epidemic in the US. Obesity and its related metabolic abnormalities contribute significantly to cardiovascular disease, and excess weight is a risk factor for multiple disease outcomes, including cancer. The purpose of this issue is to heighten the awareness of primary care physicians regarding the obesity epidemic and its long-term effects on health and on minorities and children, and to present prevention strategies and interventions.

The perennial bestseller that you MUST READ in order to fully understand the interplay between electric energy and living organisms

The Body Electric tells the fascinating story of our bioelectric selves. Robert O. Becker, a pioneer in the field of regeneration and its relationship to electrical currents in living things, challenges the established mechanistic understanding of the body. He found clues to the healing process in the long-discarded theory that electricity is vital to life. But as exciting as Becker's discoveries are, pointing to the day when human limbs, spinal cords, and organs may be regenerated after they have been damaged, equally fascinating is the story of Becker's struggle to do such original work.

The Body Electric explores new pathways in our understanding of evolution, acupuncture, psychic phenomena, and healing.

Biopolitics and the Obesity Epidemic is the first edited collection of critical perspectives on the 'obesity epidemic.' The volume provides a comprehensive discussion of current issues in the critical analysis of health, obesity and society, and the impact of obesity discourses on different individuals, social groups and institutions. Contributors from the UK, Canada, New Zealand and Australia provide original, accessible, and engaging chapters on issues such as the effects on individuals, families, youths and schools. The timely contributions offered by Biopolitics and the Obesity Epidemic to this highly topical area will be of interest to a wide range of readers, including teachers, education professionals, community health and allied professionals, and academics in areas such as education, health, youth studies, social work and psychology.

The 4th edition of Finnie's Handling the Young Child with Cerebral Palsy at Home has been updated to reflect the current practices of today. It aims to help parents assist their child with cerebral palsy (CP) towards achieving the most comfortable independence in all activities. It is hoped to show how, by using typical parenting skills, which involve guiding and exposing a child to develop through challenging experiences, the child with CP will also develop. The book is also intended to help professionals and other carers new to this field understand, support and encourage young children with CP and their families.Over the years since the first edition of this book was written ideas on appropriate therapies have changed and developed. Similarly opinion on early intervention has changed and the method of delivery of service has in some places moved from centralisation to home-based or community provision. The emphasis of this new edition however remains on a holistic approach to the child's needs seeing the difficulties in relation to the overall development of the child as a unique person from childhood to adulthood. Assessment procedures and prediction of future abilities Management of problems (including medication if appropriate) such as epilepsy, constipation, eneurisis, nourishment, difficulty with sleeping, crying, temper tantrums, sensory deficits and deformityStimulation, fitness, problem solving, compensatory strategies and ease of management New chapters include Neuroimaging, Epilepsy, Emotional health, Orthotics, Spasticity management, and Complementary and alternative medicineOver 460 revised illustrations showing different pieces of equipment which may be helpful and ways of holding and moving a child with cerebral palsyChapters on Sleeping, Feeding, Lifting and Carrying, Toileting, Communication and Fine motor movement have been completely re-written by a professional specialising in the particular field

The number of overweight and obese Americans has been rising exponentially in recent years, and as a result the United States now has one of the highest rates of obesity in the developed world. Now a leading public health problem for Americans, obesity is a regular topic for nightly news programs, scientific or medical study, and intense public debate. But this study takes a look at obesity in America, concentrating not on the condition as it exists now, but rather on how the condition was viewed, studied, and treated from 1850 to 1939. It concentrates on the images and stereotypes that were associated with fatness during these years, the various remedies that were proposed for the condition, and the often bizarre theories that were proposed to explain obesity, including the idea that ordinary tap water was fattening.The book's coverage is divided into three periods. From 1850 to 1879 there was little obesity in America, and what little existed was found almost exclusively among the upper class. Besides quackery, the condition received very little medical attention, and only negligible media reports focused on obesity as a true health issue. From 1880 to 1919, a transition of sorts began to occur as doctors, scientists, and other health professionals finally began to present a coherent theory of obesity which was based more on scientific evidence than on wild conjecture. From 1920 to 1939, obesity became accepted as a simple question of 'calories in' and 'calories out'. By this time, the condition was recognized as a big enough health issue that various groups, ranging from private employers to public health officials, began developing some of the nation's first organized weight reduction programs. One appendix looks at the average weights of American men and women as recorded in 1931.

Fat Religion: Protestant Christianity and the Construction of the Fat Body explores how Protestant Christianity contributes to the moralization of fat bodies and the proliferation of practices to conform fat bodies to thin ideals. Focusing primarily on Protestant Christianity and evangelicalism, this book brings together essays that emphasize the role of religion in the ways that we imagine, talk about, and moralize fat bodies. Contributors explore how ideas about indulgence and restraint, sin and obedience are used to create and maintain fear of, and animosity towards, fat bodies. They also examine how religious ideology and language shape attitudes towards bodily control that not only permeate Christian weight-loss programs, but are fundamental to secular diet culture as well. Furthermore, the contributors investigate how religious institutions themselves attempt to define and control the proper religious body. This volume contributes to the burgeoning field of critical fat studies by underscoring the significance of religion in the formation of historical and contemporary meanings and perceptions of fat bodies, including its moralizing role in justifying weight bias, prejudice, and privilege. The chapters in this book were originally published as a special issue of Fat Studies: An Interdisciplinary Journal of Body Weight and Society.

Supervision of Sandplay Therapy, the first book on this subject, is an internationally-based volume that describes the state of the art in supervision of sandplay therapy. Recognizing that practitioners are eager to incorporate sandplay therapy into their practice, Harriet Friedman and Rie Rogers Mitchell respond to the need for new information, and successfully translate the theories of sandplay therapy into supervision practice.

The book provides a meaningful connection and balance between theoretical principles, practical application, and ongoing therapeutic encounter involved in sandplay. Divided into six sections, contributors cover:

• original supervision models
• contemporary supervision models
• special challenges in supervision
• international sandplay supervision
• supervision of special groups
• connections with other arts therapies.

Supervision of Sandplay Therapy expands the vision of what is possible in supervision and will be vital reading for those studying supervision and sandplay therapy, as well as for those wanting to provide a depth-oriented approach during supervision.

Supervision of Sandplay Therapy, the first book on this subject, is an internationally-based volume that describes the state of the art in supervision of sandplay therapy. Recognizing that practitioners are eager to incorporate sandplay therapy into their practice, Harriet Friedman and Rie Rogers Mitchell respond to the need for new information, and successfully translate the theories of sandplay therapy into supervision practice.

The book provides a meaningful connection and balance between theoretical principles, practical application, and ongoing therapeutic encounter involved in sandplay. Divided into six sections, contributors cover:

• original supervision models
• contemporary supervision models
• special challenges in supervision
• international sandplay supervision
• supervision of special groups
• connections with other arts therapies.

Supervision of Sandplay Therapy expands the vision of what is possible in supervision and will be vital reading for those studying supervision and sandplay therapy, as well as for those wanting to provide a depth-oriented approach during supervision.

Psychodrama: Advances in Theory and Practice provides a comprehensive overview of developments in the theory and practice of psychodrama, integrating different psychodramatic schools of thought.

Psychodrama is one of the pioneering approaches of psychotherapy and is practised by thousands of practitioners and in most countries of the world. The editors of this volume bring together contributions from Europe, South America, Australia, Israel and the USA to explain and explore recent innovations. They look at how psychodrama has contributed to the development of psychotherapy, introducing concepts that have had a profound influence on other therapies. These include concepts such as role theory, the encounter, the co-unconscious, the social atom, sociometry, action research, group psychotherapy, the cycle of spontaneity and creativity, role play and many related concepts and techniques.

This book will be of great interest to all students, practitioners and trainers in the field of psychodrama. It will also appeal to professionals and students in the related fields of psychotherapy, counselling, psychology and psychiatry.

Newly updated, Cram Session in Goniometry and Manual Muscle Testing: A Handbook for Students & Clinicians, Second Edition is a descriptive quick reference guide for rehabilitation professionals organized in a "head-to-toe" format, including more than 400 photographs and supplemented with concise and illustrative examples of various techniques. The new edition of this text maintains the original essence of the first edition while touching upon updated information to speak to new clinicians. Minor revisions, such as adding color to the headers and to the sections, allow the reader easier access to the topics. An expanded appendix and up-to-date content touch on newer technology being used and developed in these areas of clinical evaluation. What is in your Cram Session: In the Goniometry section, subdivisions are broken down into type of joint, capsular pattern, average range of motion for each movement, patient positioning, goniometric alignment, patient substitutions, and alternative methods of measurement. In the Manual Muscle Testing section, subdivisions are broken into the specific movement to be tested, average range of motion, prime movers of the movement, secondary movers of the movement, anti-gravity patient position, gravity minimized patient position, stabilization and grades, substitutions for the movement, and points of interest for that particular muscle group. Cram Session in Goniometry and Manual Muscle Testing: A Handbook for Students & Clinicians, Second Edition is an informative, well-organized handbook for all students, instructors, and clinicians in physical therapy, occupational therapy, athletic training, orthopedics, or any allied health professional who treats musculoskeletal disorders.