This book illustrates applications of mathematics to various processes (physiological or artificial) involving flowing blood, including hemorheology, microcirculation, coagulation, kidney filtration and dialysis, offering a historical overview of each topic. Mathematical models are used to simulate processes normally occurring in flowing blood and to predict the effects of dysfunctions (e.g. bleeding disorders, renal failure), as well as the effects of therapies with an eye to improving treatments. Most of the models have a completely new approach that makes patient-specific simulations possible. The book is mainly intended for mathematicians interested in medical applications, but it is also useful for clinicians such as hematologists, nephrologists, cardio-surgeons, and bioengineers. Some parts require no specific knowledge of mathematics. The book is a valuable addition to mathematics, medical, biology, and bioengineering libraries.

In 1995 the Handbook of Global Optimization (first volume), edited by R. Horst, and P.M. Pardalos, was published. This second volume of the Handbook of Global Optimization is comprised of chapters dealing with modern approaches to global optimization, including different types of heuristics.

Topics covered in the handbook include various metaheuristics, such as simulated annealing, genetic algorithms, neural networks, taboo search, shake-and-bake methods, and deformation methods. In addition, the book contains chapters on new exact stochastic and deterministic approaches to continuous and mixed-integer global optimization, such as stochastic adaptive search, two-phase methods, branch-and-bound methods with new relaxation and branching strategies, algorithms based on local optimization, and dynamical search. Finally, the book contains chapters on experimental analysis of algorithms and software, test problems, and applications.

There has been significant interest for designing flight controllers for small-scale unmanned helicopters. Such helicopters preserve all the physical attributes of their full-scale counterparts, being at the same time more agile and dexterous. This book presents a comprehensive and well justified analysis for designing flight controllers for small-scale unmanned helicopters guarantying flight stability and tracking accuracy. The design of the flight controller is a critical and integral part for developing an autonomous helicopter platform. Helicopters are underactuated, highly nonlinear systems with significant dynamic coupling that needs to be considered and accounted for during controller design and implementation. Most reliable mathematical tools for analysis of control systems relate to modern control theory. Modern control techniques are model-based since the controller architecture depends on the dynamic representation of the system to be controlled. Therefore, the flight controller design problem is tightly connected with the helicopter modeling.

This book provides a step-by-step methodology for designing, evaluating and implementing efficient flight controllers for small-scale helicopters. Design issues that are analytically covered include:

An illustrative presentation of both linear and nonlinear models of ordinary differential equations representing the helicopter dynamics. A detailed presentation of the helicopter equations of motion is given for the derivation of both model types. In addition, an insightful presentation of the main rotor's mechanism, aerodynamics and dynamics is also provided. Both model types are of low complexity, physically meaningful and capable of encapsulating the dynamic behavior of a large class of small-scale helicopters.

An illustrative and rigorous derivation of mathematical control algorithms based on both the linear and nonlinear representation of the helicopter dynamics. Flight controller designs guarantee that the tracking objectives of the helicopter's inertial position (or velocity) and heading are achieved. Each controller is carefully constructed by considering the small-scale helicopter's physical flight capabilities. Concepts of advanced stability analysis are used to improve the efficiency and reduce the complexity of the flight control system. Controller designs are derived in both continuous time and discrete time covering discretization issues, which emerge from the implementation of the control algorithm using microprocessors.

Presentation of the most powerful, practical and efficient methods for extracting the helicopter model parameters based on input/output responses, collected by the measurement instruments. This topic is of particular importance for real-life implementation of the control algorithms.

This book is suitable for students and researches interested in the development and the mathematical derivation of flight controllers for small-scale helicopters. Background knowledge in modern control is required."

A clear and succinct presentation of the essentials of this subject, together with some of its applications and a generous helping of interesting exercises. Following an introductory chapter with a taste of what is to come, the next three chapters constitute a course in nonsmooth analysis and identify a coherent and comprehensive approach to the subject, leading to an efficient, natural, and powerful body of theory. The whole is rounded off with a self-contained introduction to the theory of control of ordinary differential equations. The authors have incorporated a number of new results which clarify the relationships between the different schools of thought in the subject, with the aim of making nonsmooth analysis accessible to a wider audience. End-of-chapter problems offer scope for deeper understanding.

This book is a collection of carefully reviewed papers presented during the HP-SEE User Forum, the meeting of the High-Performance Computing Infrastructure for South East Europe s (HP-SEE) Research Communities, held in October 17-19, 2012, in Belgrade, Serbia. HP-SEE aims at supporting and integrating regional HPC infrastructures; implementing solutions for HPC in the region; and making HPC resources available to research communities in SEE, region, which are working in a number of scientific fields with specific needs for massively parallel execution on powerful computing resources. HP-SEE brings together research communities and HPC operators from 14 different countries and enables them to share HPC facilities, software, tools, data and research results, thus fostering collaboration and strengthening the regional and national human network; theproject specifically supports research groups in the areas of computational physics, computational chemistry and the life sciences. The contributions presented in this book are organized in four main sections: computational physics; computational chemistry; the life sciences; and scientific computing and HPC operations.

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Recent revolutions in the world of finance have created a need for the expertise of research mathematicians in solving problems. The articles in this volume are based on recent research in methods in mathematical finance.

The coupling between acoustic waves and fluid flow motion is basically nonlinear, with the result that flow and sound modify themselves reciprocally with respect to generation and propagation properties. As a result this problem is investigated by many different communities, such as applied mathematics, acoustics and fluid mechanics. This book is the result of an international school which was held to discuss the foundation of sound--flow interactions, to share expertise and methodologies, and to promote cross-fertilization between the different disciplines involved. It consists essentially of a set of pedagogical lectures and is meant to serve not only as a compact source of reference for the experienced researcher but also as an advanced textbook for postgraduate students, and nonspecialists wishing to familiarize themselves in depth, at a research level, with this fascinating subject.

Aimed at graduate physics and chemistry students, this is the first comprehensive monograph covering the concept of the geometric phase in quantum physics from its mathematical foundations to its physical applications and experimental manifestations. It contains all the premises of the adiabatic Berry phase as well as the exact Anandan-Aharonov phase. It discusses quantum systems in a classical time-independent environment (time dependent Hamiltonians) and quantum systems in a changing environment (gauge theory of molecular physics). The mathematical methods used are a combination of differential geometry and the theory of linear operators in Hilbert Space. As a result, the monograph demonstrates how non-trivial gauge theories naturally arise and how the consequences can be experimentally observed. Readers benefit by gaining a deep understanding of the long-ignored gauge theoretic effects of quantum mechanics and how to measure them.

Though the volume covers 22 papers by 36 authors from 12 countries, the history in the background is bound to Hungary where, in 1973 Andras Pn kopa started to lay the foundation of a scientific forum, which can be a regular meeting spot for experts of the world in the field. Since then, there has been a constant interest in that forum. Headed at present by Tamas Rapcsak, the Laboratory of Operations Research and Decisions Systems of the Computer and Automation Institute, Hungarian Academy of Sciences followed the tradition in every respect, namely conferences were organized almost in every second year and in the same stimulating area, in the Matra mountains. The basic fields were kept, providing opportunities for the leading personalities to give voice to their latest results. The floor has been widened recently for the young generation, ensuring this way both a real location for the past, present and future experts to meet and also the possibility for them to make the multicoloured rainbow of the fields unbroken and continuous. The volume is devoted to the memory of Steven Vajda, one of the pioneers on mathematical programming, born is Hungary. In 1992 he took part in the XIth International Conference on Mathematical Programming at Matrafiired where, with his bright personality, he greatly contributed to the good spirituality of the event. We thank Jakob Krarup for his reminiscence on the life and scientific activities of late Steven Vajda."

Written to be more rigorous than other books on the same topics No other book on the topics explores programming and software in this manner Requires only undergraduate prerequisites

The book provides a self-contained introduction to underlying techniques, as well as a compendium of theory and a guide to the author's Fortran 90 software for nonlinear algebraic systems and global, constrained optimization with automatic result verification. Besides introductory and survey material, the book contains unique research results. The book also contains non-traditional ideas concerning non-smooth optimization. Thus, the book should be a valuable reference to applied mathematicians and computational scientists and engineers. With numerous examples and exercises, as well as leads for future research, the book can be used as a graduate text or reference on interval arithmetic, automatic differentiation and interval fixed point theory. The book can also serve as a user's guide for the nonlinear equations and optimization software, available free of charge from the author, for the author's general Fortran 90 interval arithmetic package, or for the associated automatic differentiation package. Audience: Researchers in operations research, numerical analysis, computational chemistry, computer-aided geometric design and computational geometry, robot kinematics, remote sensing. Also suitable for graduate and topics courses in numerical analysis, optimization, and operations research.

The finite difference method (FDM) hasbeen used tosolve differential equation systems for centuries. The FDM works well for problems of simple geometry and was widely used before the invention of the much more efficient, robust finite element method (FEM). FEM is now widely used in handling problems with complex geometry. Currently, we are using and developing even more powerful numerical techniques aiming to obtain more accurate approximate solutions in a more convenient manner for even more complex systems. The meshfree or meshless method is one such phenomenal development in the past decade, and is the subject of this book. There are many MFree methods proposed so far for different applications. Currently, three monographs on MFree methods have been published. Mesh Free Methods, Moving Beyond the Finite Element Method d by GR Liu (2002) provides a systematic discussion on basic theories, fundamentals for MFree methods, especially on MFree weak-form methods. It provides a comprehensive record of well-known MFree methods and the wide coverage of applications of MFree methods to problems of solids mechanics (solids, beams, plates, shells, etc.) as well as fluid mechanics. The Meshless Local Petrov-Galerkin (MLPG) Method d by Atluri and Shen (2002) provides detailed discussions of the meshfree local Petrov-Galerkin (MLPG) method and itsvariations. Formulations and applications of MLPG are well addressed in their book.

The Mathematics of Darwin 's Legacy presents a general overview of mathematical models in the context of evolution. It covers a wide range of topics such as population genetics, population dynamics, speciation, adaptive dynamics, game theory, kin selection, and stochastic processes. Written by leading scientists working at the interface between evolutionary biology and mathematics the book is the outcome of a conference commemorating Charles Darwin's 200th birthday, and the 150th anniversary of the first publication of his book "On the origin of species." Its chapters vary in format between general introductory and state-of-the-art research texts in biomathematics, in this way addressing both students and researchers in mathematics, biology and related fields. Mathematicians looking for new problems as well as biologists looking for rigorous description of population dynamics will find this book fundamental.

The main contents and character of the monograph did not change with respect to the first edition. However, within most chapters we incorporated quite a number of modifications which take into account the recent development of the field, the very valuable suggestions and comments that we received from numerous colleagues and students as well as our own experience while using the book. Some errors and misprints in the first edition are also corrected. Reiner Horst May 1992 Hoang Tuy PREFACE TO THE FIRST EDITION The enormous practical need for solving global optimization problems coupled with a rapidly advancing computer technology has allowed one to consider problems which a few years aga would have been considered computationally intractable. As a consequence, we are seeing the creation of a large and increasing number of diverse algorithms for solving a wide variety of multiextremal global optimization problems. The goal of this book is to systematically clarify and unify these diverse approaches in order to provide insight into the underlying concepts and their pro perties. Aside from a coherent view of the field much new material is presented."

The volume is dedicated to Stephen Smale on the occasion of his 80th birthday.Besides his startling 1960 result of the proof of the Poincare conjecture for all dimensionsgreater than or equal to five, Smale's ground breaking contributions invarious fields in Mathematics have marked the second part of the 20th century andbeyond. Stephen Smale has done pioneering work in differential topology, globalanalysis, dynamical systems, nonlinear functional analysis, numerical analysis, theoryof computation and machine learning as well as applications in the physical andbiological sciences and economics. In sum, Stephen Smale has manifestly brokenthe barriers among the different fields of mathematics and dispelled some remainingprejudices. He is indeed a universal mathematician. Smale has been honoredwith several prizes and honorary degrees including, among others, the Fields Medal(1966), The Veblen Prize (1966), the National Medal of Science (1996) and theWolfPrize (2006/2007)."

Bringing together the key ideas from nonequilibrium statistical mechanics and powerful methodology from quantum field theory, this 2008 book captures the essence of nonequilibrium quantum field theory. Beginning with the foundational aspects of the theory, the book presents important concepts and useful techniques, discusses issues of basic interest, and shows how thermal field, linear response, kinetic theories and hydrodynamics emerge. It also illustrates how these concepts are applied to research topics including nonequilibrium phase transitions, thermalization in relativistic heavy ion collisions, the nonequilibrium dynamics of Bose-Einstein condensation, and the generation of structures from quantum fluctuations in the early Universe. This self-contained book is a valuable reference for graduate students and researchers in particle physics, gravitation, cosmology, atomic-optical and condensed matter physics. It has been reissued as an Open Access publication on Cambridge Core.

Equations of the Ginzburg Landau vortices have particular applications to a number of problems in physics, including phase transition phenomena in superconductors, superfluids, and liquid crystals. Building on the results presented by Bethuel, Brazis, and Helein, this current work further analyzes Ginzburg-Landau vortices with a particular emphasis on the uniqueness question.

The authors begin with a general presentation of the theory and then proceed to study problems using weighted Holder spaces and Sobolev Spaces. These are particularly powerful tools and help us obtain a deeper understanding of the nonlinear partial differential equations associated with Ginzburg-Landau vortices. Such an approach sheds new light on the links between the geometry of vortices and the number of solutions.

Aimed at mathematicians, physicists, engineers, and grad students, this monograph will be useful in a number of contexts in the nonlinear analysis of problems arising in geometry or mathematical physics. The material presented covers recent and original results by the authors, and will serve as an excellent classroom text or a valuable self-study resource."

Semi-infinite programming (SIP) deals with optimization problems in which either the number of decision variables or the number of constraints is finite. This book presents the state of the art in SIP in a suggestive way, bringing the powerful SIP tools close to the potential users in different scientific and technological fields. The volume is divided into four parts. Part I reviews the first decade of SIP (1962-1972). Part II analyses convex and generalised SIP, conic linear programming, and disjunctive programming. New numerical methods for linear, convex, and continuously differentiable SIP problems are proposed in Part III. Finally, Part IV provides an overview of the applications of SIP to probability, statistics, experimental design, robotics, optimization under uncertainty, production games, and separation problems. Audience: This book is an indispensable reference and source for advanced students and researchers in applied mathematics and engineering.

This book teaches mathematical structures and how they can be applied in environmental science. Each chapter presents story problems with an emphasis on derivation. For each of these, the discussion follows the pattern of first presenting an example of a type of structure as applied to environmental science. The definition of the structure is presented, followed by additional examples using MATLAB, and analytic methods of solving and learning from the structure.

Interest in constrained optimization originated with the simple linear pro gramming model since it was practical and perhaps the only computationally tractable model at the time. Constrained linear optimization models were soon adopted in numerous application areas and are perhaps the most widely used mathematical models in operations research and management science at the time of this writing. Modelers have, however, found the assumption of linearity to be overly restrictive in expressing the real-world phenomena and problems in economics, finance, business, communication, engineering design, computational biology, and other areas that frequently demand the use of nonlinear expressions and discrete variables in optimization models. Both of these extensions of the linear programming model are NP-hard, thus representing very challenging problems. On the brighter side, recent advances in algorithmic and computing technology make it possible to re visit these problems with the hope of solving practically relevant problems in reasonable amounts of computational time. Initial attempts at solving nonlinear programs concentrated on the de velopment of local optimization methods guaranteeing globality under the assumption of convexity. On the other hand, the integer programming liter ature has concentrated on the development of methods that ensure global optima. The aim of this book is to marry the advancements in solving nonlinear and integer programming models and to develop new results in the more general framework of mixed-integer nonlinear programs (MINLPs) with the goal of devising practically efficient global optimization algorithms for MINLPs."

An introduction to certain aspects of developments in the modern theory of dynamics and simulation for a wide audience of scientifically literate readers. Unlike general texts on chaos theory and dynamical systems theory, this book follows the work on a specific problem at the very beginning of the modern era of dynamics, from its inception in 1954 through the early 1970s. It discusses such problems as the nonlinear oscillator simulation, the seminal discoveries at MIT in the early 1950s, the mathematical rediscovery of solitons in the late 1950s and the general problems of computability. In following these developments, the initial development of many of the now standard techniques of nonlinear modelling and numerical simulation are seen. No other text focuses so tightly and covers so completely one specific, pernicious problem at the heart of dynamics.

This is a blind refereed serial publication published on an annual basis. The objective of this research annual is to present state-of-the-art studies in the integration of mathematical programming into financial planning and management. The literature and techniques in financial planning and management are becoming increasingly complex. It is hoped that the monographs aid in the dissemination of research efforts in quantitative financial analysis. The topics will normally include cash management, capital budgeting, financial decisions, portfolio management and performance analysis, and financial planning models. The analyses generally include mixed integer programming, goal programming, biased regression techniques and simulation models, application of forecasting methodologies to such areas as sales, marketing, and strategic decision making (an accurate, robust forecast is critical to effective decision making). It is the hope of the editors that the majority of the papers will simulate questions and possible solutions that are of interest to financial planners.

This selection of outstanding articles - an outgrowth of the QMath9 meeting for young scientists - covers new techniques and recent results on spectral theory, statistical mechanics, Bose-Einstein condensation, random operators, magnetic Schrodinger operators and more. The book's pedagogical style makes it a useful introduction to the research literature for postgraduate students. For more expert researchers it will serve as a concise source of modern reference."

This book offers a thorough and up-to-date treatment of the use of morphometric procedures in a wide variety of contexts. As one of the most dynamic and popular fields on the contemporary biological scene, morphometrics is gaining notice among researchers and students as a necessary complement to molecular studies in the understanding and maintenance of biodiversity. This is the first reference to meet that growing need.

This volume contains, in part, a selection of papers presented at the sixth Australian Optimization Day Miniconference (Ballarat, 16 July 1999), and the Special Sessions on Nonlinear Dynamics and Optimization and Operations Re search - Methods and Applications, which were held in Melbourne, July 11-15 1999 as a part of the Joint Meeting of the American Mathematical Society and Australian Mathematical Society. The editors have strived to present both con tributed papers and survey style papers as a more interesting mix for readers. Some participants from the meetings mentioned above have responded to this approach by preparing survey and 'semi-survey' papers, based on presented lectures. Contributed paper, which contain new and interesting results, are also included. The fields of the presented papers are very large as demonstrated by the following selection of key words from selected papers in this volume: * optimal control, stochastic optimal control, MATLAB, economic models, implicit constraints, Bellman principle, Markov process, decision-making under uncertainty, risk aversion, dynamic programming, optimal value function. * emergent computation, complexity, traveling salesman problem, signal estimation, neural networks, time congestion, teletraffic. * gap functions, nonsmooth variational inequalities, derivative-free algo rithm, Newton's method. * auxiliary function, generalized penalty function, modified Lagrange func tion. * convexity, quasiconvexity, abstract convexity.