Dealing with the volume, complexity, and diversity of data currently being generated by scientific experiments and simulations often causes scientists to waste productive time. Scientific Data Management: Challenges, Technology, and Deployment describes cutting-edge technologies and solutions for managing and analyzing vast amounts of data, helping scientists focus on their scientific goals.

The book begins with coverage of efficient storage systems, discussing how to write and read large volumes of data without slowing the simulation, analysis, or visualization processes. It then focuses on the efficient data movement and management of storage spaces and explores emerging database systems for scientific data. The book also addresses how to best organize data for analysis purposes, how to effectively conduct searches over large datasets, how to successfully automate multistep scientific process workflows, and how to automatically collect metadata and lineage information.

This book provides a comprehensive understanding of the latest techniques for managing data during scientific exploration processes, from data generation to data analysis. Enhanced by numerous detailed color images, it includes real-world examples of applications drawn from biology, ecology, geology, climatology, and more.

Check out Dr. Shoshani discuss the book during an interview with International Science Grid This Week (iSGTW): http: //www.isgtw.org/?pid=1002259

This book was written to venture beyond interpretations of Cormac McCarthy's characters as simple, antinomian, and non-psychological; and of his landscapes as unrelated to the violent arcs of often orphaned and always emotionally isolated and socially detached characters. As McCarthy usually eschews direct indications of psychology, his landscapes allow us to infer much about their motivations. The relationship of ambivalent nostalgia for domesticity to McCarthy's descriptions of space remains relatively unexamined at book length, and through less theoretical application than close reading. By including McCarthy's latest book, this study offer the only complete study of all nine novels. Within McCarthy studies, this book extends and complicates a growing interest in space and domesticity in his work. The author combines a high regard for McCarthy's stylistic prowess with a provocative reading of how his own psychological habits around gender issues and family relations power books that only appear to be stories of masculine heroics, expressions of misogynistic fear, or antinomian rejections of civilized life.

The definitive guide to the principles and practice of experimental organic chemistry - fully updated and now featuring more than 100 experiments The latest edition of this popular guide to experimental organic chemistry takes students from their first day in the laboratory right through to complex research procedures. All sections have been updated to reflect new techniques, equipment and technologies, and the text has been revised with an even sharper focus on practical skills and procedures. The first half of the book is devoted to safe laboratory practice as well as purification and analytical techniques; particularly spectroscopic analysis. The second half contains step-by-step experimental procedures, each one illustrating a basic principle, or important reaction type. Tried and tested over almost three decades, over 100 validated experiments are graded according to their complexity and all are chosen to highlight important chemical transformations and to teach key experimental skills. New sections cover updated health and safety guidelines, additional spectroscopic techniques, electronic notebooks and record keeping, and techniques, such as semi-automated chromatography and enabling technologies such as the use of microwave and flow chemistry. New experiments include transition metal-catalysed cross-coupling, organocatalysis, asymmetric synthesis, flow chemistry, and microwave-assisted synthesis. Key aspects of this third edition include: * Detailed descriptions of the correct use of common apparatus used in the organic laboratory * Outlines of practical skills that all chemistry students must learn * Highlights of aspects of health and safety in the laboratory, both in the first section and throughout the experimental procedures * Four new sections reflecting advances in techniques and technologies, from electronic databases and information retrieval to semi-automated chromatography * More than 100 validated experiments of graded complexity from introductory to research level * A user-friendly experiment directory * An instructor manual and PowerPoint slides of the figures in the book available on a companion website A comprehensive guide to contemporary organic chemistry laboratory principles, procedures, protocols, tools and techniques, Experimental Organic Chemistry, Third Edition is both an essential laboratory textbook for students of chemistry at all levels, and a handy bench reference for experienced chemists.

This is the second volume of a two-volume guide to designing, conducting and interpreting laboratory and field experiments in a broad range of topics associated with hydraulic engineering. Specific guidance is provided on methods and instruments currently used in experimental hydraulics, with emphasis on new and emerging measurement technologies and methods of analysis. Additionally, this book offers a concise outline of essential background theory, underscoring the intrinsic connection between theory and experiments. This book is much needed, as experimental hydraulicians have had to refer to guidance scattered in scientific papers or specialized monographs on essential aspects of laboratory and fieldwork practice. The book is the result of the first substantial effort in the community of hydraulic engineering to describe in one place all the components of experimental hydraulics. Included is the work of a team of more than 45 professional experimentalists, who explore innovative approaches to the vast array of experiments of differing complexity encountered by today's hydraulic engineer, from laboratory to field, from simple but well-conceived to complex and well-instrumented. The style of this book is intentionally succinct, making frequent use of convenient summaries, tables and examples to present information. All researchers, practitioners, and students conducting or evaluating experiments in hydraulics will find this book useful.

"Essential Laboratory Skills for Biosciences" is an essential companion during laboratory sessions. It is designed to be simple and give clear step by step instructions on essential techniques, supported by relevant diagrams. The book includes the use of particular equipment and how to do simple calculations that students come across regularly in laboratory practicals.

Written by experienced lecturers this handy pocket book provides: Simple to follow laboratory techniquesClear use of diagrams and illustrations to explain techniques, procedures and equipmentStep by step worked out examples of calculations including concentrations, dilutions and molarity

Suitable for all first year university students, the techniques in the book will also be useful for postgraduate and final year project students and enhance the practical and theoretical knowledge of all those studying bioscience related subjects.

"Provides a lot of reading pleasure and many new insights." —Journal of Molecular Structure

"This is the most entertaining, stimulating and useful book which can be thoroughly recommended to anyone with an interest in computer simulation." —Contemporary Physics

"A very useful introduction . . . more interesting to read than the often dry equation-based texts." —Journal of the American Chemical Society

Written especially for the novice, Molecular Dynamics Simulation demonstrates how molecular dynamics simulations work and how to perform them, focusing on how to devise a model for specific molecules and then how to simulate their movements using a computer. This book provides a collection of methods that until now have been scattered through the literature of the last 25 years. It reviews elements of sampling theory and discusses how modern notions of chaos and nonlinear dynamics explain the workings of molecular dynamics.

Stresses easy-to-use molecules

• Provides sample calculations and figures
• Includes four complete FORTRAN codes

This text provides the reader with a comprehensive understanding of the key ideas behind the physics of particle accelerators. Supported by a clear mathematical treatment and a range of calculations which develop a genuine feeling for the subject, it is a thorough introduction to the many aspects of accelerator physics.

Teaches proper procedures for using tools and analytical methods in a regulated lab setting
All regulated laboratories, including pharmaceutical, clinical testing, and food and cosmetics testing laboratories, must properly execute the calibration of instruments and validation of analytical methods. Following correct procedures ensures the generation of reliable data, which leads to the manufacture of safe and effective products.

Analytical Method Validation and Instrument Performance Verification provides a uniquely practical approach to method validation and instrument performance verification. Each chapter starts with general requirements, then moves to the strategies and steps taken to fulfill these conditions, and finishes with a discussion of practical problems and their solutions. Coverage includes: Method validation of potency, related substances, and dissolution testing Validation for pharmaceutical excipients, heavy metals, and bioanalysis Performance verification for common analytical instruments including HPLC, UV-Vis spectrophotometers, and pH meters The LCMS system calibration Proper environmental chamber qualification Entire qualification process for computer equipment, hardware, and software Validation of Excel spreadsheets Regulatory requirements of the FDA, ICH, Europe, and Japan

Full of practical tips on validation techniques and detailed discussions of instrument performance verification, this comprehensive guide represents a one-stop reference for remaining current in today's regulatory environment.

Analytical Method Validation and Instrument Performance Verification provides an invaluable working reference for laboratory managers, calibrationscientists, and research and development scientists.

This special issue is devoted to the topic of "risk and resilience" in human development, a topic that epitomizes the complexity of human development as a process of constancy and change throughout life. The three empirical papers in this issue represent strong contributions to the growing corpus of research on risk and resilience in human development. The first one focuses on the uniquely vulnerable population of urban ethnic minority adolescent males. The second paper focuses on the risk and resilience from trauma in a sample of mostly Caucasian individuals from rural Iowa, who were at the last assessment, in the midst of transition into young adulthood. It measures an array of mental disorders outcomes and reveals the theoretical importance of timing of the risk factor. The last paper is a study begun in 1978 of a cohort of individuals with serious adolescent-onset mental disorder. It compares these individuals against the risk and resilience profiles of a matched sample without serious adolescent-onset psychiatric disorder. In sum this issue adds to the corpus of the frontiers of resilience research.

It is widely recognised that students on present-day chemistry courses need to develop a portfolio of practical skills. Progressive Development of Practical Skills in Chemistry is the second in a series of publications from the Royal Society of Chemistry which are directed towards the early part of an undergraduate chemistry programme. This book features a variety of practical activities, spanning a wide range of chemistry. Activities are arranged in order of increasing skills development and demand, and each is accompanied by a guide for demonstrators. A technical guide is also included detailing all reagent and equipment requirements. Trialled in universities across the UK pre-publication, students and lecturers will welcome this book as an aid to the development of skills in degree courses.

This book provides the scientific and technical background materials of non-destructive methods of microscopic analysis that are suitable for analysing works of art, museum pieces and archeaological artefacts. Written by experts in the field, this multi-author volume contains a number of case studies, illustrating the value of these methods. The book is suited to natural scientists and analysts looking to increase their knowledge of the various methods that are currently available for non-destructive analysis. It is also the perfect resource for museum curators, archaeologists and art-historians seeking to identify one or more suitable methods of analysis that could solve material-related problems.

Reference materials play an important role in analytical chemistry, where they are used by analysts for a variety of purposes, including: checking and calibrating instruments; validating methods and estimating the uncertainty of analytical measurements; checking laboratory and analyst performance; and internal quality control. This book provides guidance and information for the users of certified reference materials (CRMs), explaining how they can best be used to achieve valid analytical measurements and improve quality in the analytical laboratory. General information on CRMs and how they are produced sets the scene for readers. The statistics relating to CRM use are then explained in an easy-to-understand manner, and this is followed by sections covering the main uses of CRMs. Detailed worked examples are used throughout. Structured and comprehensive in coverage, this book will be welcomed by all users of certified reference materials.

This book covers one of the most neglected areas in environmental trace analysis, namely that of sample preparation. The text discusses all of the necessary steps for analysing a sample for both trace metals and organics, from the initial sampling protocols, through the range of possible sample preparation methods, and leading finally to the analysis and recording of data. Detailed information is provided on the specific methods to follow for preparing a sample for metal and organic analyses.

The topics covered include the following:

• Basic laboratory skills

• Investigative approaches for sample preparation

• Sampling

• Storage of samples

• Sample preparation for inorganic analysis - solids and liquids

• Sample preparation for organic analysis - solids, liquids and volatile compounds

• Pre-concentration approaches

• Instrumental techniques for trace analysis

• Up-to-date information on the latest developments in sample preparation for metals and organics.

• Written in an open learning/distance learning style, it is ideal for use as a self-study guide or as the basis of a taught course.

• The provision of a comprehensive bibliography to guide the reader to more specialized texts and sources.

Covering both underlying theory and practical applications, Laser Safety provides a unique and readily-understandable review of current laser safety. This resource explains in detail the biological effects of laser radiation, particularly on the eye, and the provisions and requirements of the international laser safety standard IEC 60825-1, including a full description of the recently revised system of laser classification. It elucidates the rationale for the often-complex laser emission and exposure limits given in the standard, and provides detailed guidance for using the standard to carry out quantitative laser assessments. The authors also discuss practical issues of risk assessment, safety controls, eye protection, and laser safety management. This practical and comprehensive handbook will be useful for anyone involved in laser safety, including academic and medical researchers, laser manufacturers, and compliance officers.

The evolution of observational instruments, simulation techniques, and computing power has given aquatic scientists a new understanding of biological and physical processes that span temporal and spatial scales. This has created a need for a single volume that addresses concepts of scale in a manner that builds bridges between experimentalists and theoreticians in aquatic ecology.

Handbook of Scaling Methods in Aquatic Ecology: Measurement, Analysis, Simulation is the first comprehensive compilation of modern scaling methods used in marine and freshwater ecological research. Written by leading researchers, it presents a systematic approach to dealing with space and time in aquatic ecology. This is a compendium that analyzes themes related to the response or behavior of organisms to processes occurring over multiple spatial and temporal scales.

This book covers: novel techniques for data collection, focusing on processes over a broad range of scales (from bacteria to ocean basins); newly-developed concepts and data analysis algorithms; and innovative computer models and simulations to mimic complex biological processes.

The Handbook serves as a reference volume for investigators seeking insight into new experimental approaches and data analysis, as well as the sensor design required for optimal sampling. Many of the algorithms and models provided are directly applicable to your experimental data. This comprehensive treatment of scaling methods and applications can help foster a unified understanding of subject matter among the modeling, experimental, and field research communities.

* Expert, up-to-date guidance on the appropriate techniques of local chemical analysis
* Comprehensive. This volume is an ideal starting point for material research and development, bringing together a number of techniques usually only found in isolation
* Recent examples of the applications of techniques are provided in all cases

Helping to solve the problems of materials scientists in academia and industry, this book offers guidance on appropriate techniques of chemical analysis of materials at the local level, down to the atomic scale. Comparisons are made between various techniques in terms of the nature of the probe employed. The detection limit and the optimum spatial resolution is also considered, as well as the range of atomic number that may be identified and the precision and methods of calibration, where appropriate.

"The Local Chemical Analysis of Materials" is amply illustrated allowing the reader to easily see typical results. It includes a comparative table of techniques to aid selection for analysis and a table of acronyms, particularly valuable in this jargon-riddled area.

A lab manual for the General Chemistry course, Beran has been popular for the past nine editions because of its broad selection of experiments, clear layout, and design. Containing enough material for two or three terms, this lab manual emphasizes chemical principles as well as techniques. In addition, the manual helps students understand the timing and situations for various techniques.

"Veterinary Laboratory Medicine" covers all aspects of basic clinical biochemistry and haematology, and includes test-by-test interpretation of laboratory results. Information is provided on sampling techniques, the selection and use of an external laboratory, as well as near-patient testing and the practice laboratory. Also included are step-by-step instructions for most commonly used point-of-care tests, a guide to the evaluation of instruments for in-practice use, and a detailed explanation of the principles of impedance counting and photometric analysis. The book will be ideal for practitioners who require a guide to laboratory work, and for veterinary students studying laboratory medicine and clinical pathology.

The second edition has been fully updated to reflect advances in diagnostic techniques, and includes new chapters on diagnostic endocrinology and feline virus testing as well as a much expanded chapter on diagnostic profiling and pattern recognition.

The latest version of a bestseller, Hazardous Laboratory Chemicals Disposal Guide, Third Edition includes individual entries for over 300 compounds. The extensive list of references has been updated and includes entries for 15 pesticides commonly used in greenhouses. Emphasis is placed on disposal methods that turn hazardous waste material into non-toxic products. These methods fall into several categories, including acid/base neutralization, oxidation or reduction, and precipitation of toxic ions as insoluble solids. The text also provides data on hazardous reactions of chemicals, assisting laboratory managers in developing a plan of action for emergencies such as the spill of any of the chemicals listed.

The knowledge base of chromatography continued to expand throughout the 1990s owing to its many applications to problems of contemporary interest in industry, life and environmental sciences. Organizing this information into a single text for a diverse group of scientists has become increasingly difficult. The present book stemmed from the desire to revise Chromatography Today, written by the same author with Salwa K. Poole, and published in 1991. This title is considered to be one of the definitive texts on chromatography. It was soon realized however, that a simple revision would not provide the desired result of a contemporary picture of the practice of chromatography at the turn of the century. The only workable solution was to start afresh, maintaining the same general philosophy and concept for Chromatography Today where possible, while creating essentially a new book.
The format of the new book is modular, with extensive cross-references to permit rapid location of related material using different separation concepts. Important features are extensive tabulation of essential data for performing separations and an extensive bibliography to the most recent literature.
This title is intended as a suitable text for graduate level courses in the separation sciences and as a self-study guide for professional chromatographers wishing to refresh their background in this rapidly expanding field.
The Essence of Chromatography presents a comprehensive survey of modern chromatography and is an effective replacement for Chromatography Today.
.Comprehensive and authoritative coverage of chromatographic techniques
.Contains extensive coverage of recent literature on this subject
.Ideal text for graduates and suitable for professional chromatographers"

We are now accustomed to conceive of science as an instrumental activity, producing numbers, measurements and graphs by means of sophisticated devices. This book investigates the historical process that gave rise to this instrumental culture. The contributors trace the displacement of instruments across the globe, the spread of practices or precision and the circulation and appropriation of skills and knowledge.
Through comparative and contextual approaches, the volume confronts the tension between the local and the global, examining the process of the universalization of science. Bringing together case studies ranging from the seventeenth to the twentieth centuries, contributors discuss French, German and British initiatives, as well as the knowledge and techniques of travellers in countries such as India, Africa, South East Asia and the Americas.
Students and researchers interested in the history of science in both Western and non-Western cultures will find this book a valuable and thought-provoking read.

eBook available with sample pages: 0203219015

This book is divided into two parts. In the first part we introduce the foundations of special relativity, such as, the inertial frame of reference, the definition of simulataneity, and Einstein's two basic hypotheses. We give the main relativistic effects, e.g. the relativity of simultaneity, velocity addition, length-contraction, the apparent shape of a moving body, time-dilation, Doppler effect, and the Thomas precession, In particular, the simultaneity problem and slow transport of clocks are investigated in detail by means of the test theories of special relativity. In the second part, variant types of experiments performed up to now are analyzed and compared to the predictions of special relativity. This shows that the experiments are a test of the two-way speed of light, but not of the one-way speed of light.

The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.

An outstanding practical guide to the most common chemometric methods in use today

Chemometrics explains how to apply the most widely used pattern recognition and multivariate calibration techniques to solve data analysis problems. This practical guide describes all key methods in terms of processes and applications in order to help the reader easily identify the best technique for a given situation.

Drawing on years of industrial experience with chemometric tools, the authors share their six basic steps, or "habits," for achieving reliable chemometric results, and cover key areas such as:

• Defining and understanding the problem
• Experimental planning and design
• Preprocessing of samples and variables
• Supervised and unsupervised pattern recognition
• Classical and inverse methods of multivariate calibration

Complete with helpful chapter-end summaries, technical references, and more, this book is an invaluable hands-on resource for analytical chemists and laboratory scientists who use chemometrics in their work.

The first edition of this classic book remains one of the very few introductory books covering both theoretical and practical aspects of thermal analysis (TA). This new edition includes a much enlarged section on MDSC, in which the instrument is described and a critical appraisal of the technique presented. Other additions include new sections on rate-controlled TGA, OTTER, and Specific Heat Spectroscopy, and a thoroughly updated section on X-Ray DSC. This very practical book is a must for people who use thermal analysis techniques in their everyday work. "An excellent introductory text" — Review of 1st Edition.