Description
Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique.
.Provides a basic overview of microarray technology and available platforms for those unfamiliar with the technology
.Includes detailed discussion of experimental design and analysis of microarray experiments, giving first-time users valuable information that can be tailored to their own research needs
.Provides discussion of such hot areas as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
Expert author team highlights the utility of the technology using examples from human health and disease--e.g., malaria and cancer diagnostics.

This edited book serves as a vital resource on the contributions of microorganisms to advances in nanotechnology, establishing their applications in diverse areas of biomedicine, environment, biocatalysis, food and nutrition, and renewable energy. It documents the impacts of microorganisms in nanotechnology leading to further developments in microbial nanobiotechnology. This book appeals to researchers and scholars of microbiology, biochemistry and nanotechnology.

Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, "Medicinal and Aromatic Plants: Healthcare and Industrial Applications", highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.

Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.

Biotechnology is a diverse, complex, and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. This latest volume of "Biotechnology Annual Review" comprises expert reviews on a diverse range of topics, ranging from gene expression microarray analysis to the use of ethnomedicines and ethnomedicinal phytophores to treat herpes viruses. Such a diverse range of review topics will keep biotechnologists of all levels up-to-date on the latest in the vast field of biotechnology and deepen their understanding of the many facets of the field as a whole.
*More than 150 figures elucidate and reinforce key points
*Inclusion of reviews of such hot-topics as arginine methylation in health and disease
*Wide variety of coverage keeps biotechnologists up-to-date on many facets of the field

Stephen Heywood was twenty-nine years old when he learned that he was dying of ALS -- Lou Gehrig's disease. Almost overnight his older brother, Jamie, turned himself into a genetic engineer in a quixotic race to cure the incurable. His Brother's Keeper is a powerful account of their story, as they travel together to the edge of medicine.

The book brings home for all of us the hopes and fears of the new biology. In this dramatic and suspenseful narrative, Jonathan Weiner gives us a remarkable portrait of science and medicine today. We learn about gene therapy, stem cells, brain vaccines, and other novel treatments for such nerve-death diseases as ALS, Alzheimer's, and Parkinson's -- diseases that afflict millions, and touch the lives of many more.

"The Heywoods' story taught me many things about the nature of healing in the new millennium," Weiner writes. "They also taught me about what has not changed since the time of the ancients and may never change as long as there are human beings -- about what Lucretius calls 'the ever-living wound of love.'"This P.S. edition features an extra 16 pages of insights into the book, including author interviews, recommended reading, and more.

The book comprehensively covers the different topics of graphene based biopolymer and nanocomposites, mainly synthesis methods for the composite materials, various characterization techniques to study the superior properties and insights on potential advanced applications.The book will address and rectify the complications of using plastics that are non-degradable and has abhorrent impact on environment. The limitations of properties of biopolymer can be vanquished by employing graphene as a nanomaterial. Outstanding properties of graphene in accordance with biopolymer can be utilized to develop applications like water treatment, tissue engineering, photo-catalysts, super-absorbents. This is a useful reference source for both engineers and researchers working in composite materials science as well as the students attending materials science, physics, chemistry, and engineering courses.

Algae are simple, primitive, heterogeneous, autotrophic, eukaryotic or prokaryotic organisms that lead a symbiotic, parasitic or free-living mode of life. Microalgae and macroalgae possess great potential in various fields of application. Microalgae are ubiquitous and extremely diverse microorganisms that can accumulate toxic contaminants and heavy metals from wastewater, making them a superior candidate to become a powerful nanofactory. Algae were discovered to reduce the presence of metal ions, and afterwards aid in the biosynthesis of nanoparticles. Since algae-mediated biogenic nanoparticles are eco-friendly, cost-effective, high-yielding, speedy and energy-efficient, a large number of studies have been published on them in the last few years. This book focuses on recent progress on the utilization of algae for the synthesis of nanoparticles, their characterization and the possible mechanisms involved. Bioprospecting Algae for Nanosized Materials describes the synthesis of algal nanomaterials and its application in various fields for sustainable development. This book outlines the procedures to prepare phyconanomaterials, techniques to utilize the nanomaterials, and applications in agriculture, environment and medicine.

Cancer Nanotheranostics, Volume 2 continues the discussion of the important work being done in this field of cancer nanotechnology. The contents of these two volumes are explained in detail as follows. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials, and nano-antibodies. This important second volume discusses nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nanoerythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, safety of nanobiomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics. Volume 2 is a vital continuation of this two-volume set. Together, these two volumes create a comprehensive and unique examination of this important area of research.

This book aims to comprehensively summarize the current research status of nanomaterials and cell biology. It highlights the biological effects and biomedical applications of nanomaterials for specific diseases, bone tissue engineering, and skeletal muscle regeneration. It also provides the details of the biomedical applications of nucleic acid nanomaterials in drug delivery carriers, antimicrobial therapy, vaccine, and neurodegenerative diseases. Therefore, this book renders the audience a better understanding of nanomaterials along with the diverse applications in the cell biology field from recent works to perspectives.

This book examines Ghana's use of the fingerprint biometric technology in order to further conversations about localization championed by technical communication scholars. Localization, in this case, refers to the extent to which users demonstrate their knowledge of use by subverting and reconfiguring the purpose of technology to solve local problems. Dorpenyo argues that the success of a technology depends on how it meets the users' needs and the creative efforts users put into use situations. In User Localization Strategies in the Face of Technological Breakdown, Dorpenyo advocates studying how users of technological systems construct knowledge about the technology and develop local strategies to solve technological breakdowns. By analyzing technical documents and interview transcripts, the author identifies and advances three user localization strategies: linguistic localization, subversive localization, and user-heuristic experience localization, and considers how biometric systems can become a tool of marginalization.

This book reviews the current knowledge on tunable hydrogels, including the range of different materials and applications, as well as the existing challenges and limitations in the field. It covers various aspects of the material design, particularly highlighting biological responsiveness, degradability and responsiveness to external stimuli. In this book, readers will discover original research data and state-of-the-art reviews in the area of hydrogel technology, with a specific focus on biotechnology and medicine. Written by leading experts, the contributions outline strategies for designing tunable hydrogels and offer a detailed evaluation of the physical and synthetic methods currently employed to achieve specific hydrogel properties and responsiveness. This highly informative book provides important theoretical and practical insights for scholars and researchers working with hydrogels for biomedical and biotechnological applications.

New technologies will have an increasing effect on prospects for development and growth in the world economy. Technology and Innovation in the International Economy contains extensive and detailed assessments of two key areas of technological innovation which present both a threat and an opportunity for developing countries: microelectronics and biotechnology.The two major review essays - Jeffrey James on microelectronic technology and Martin Fransman on biotechnology - assess the impact of these new technologies on production, trade, employment and welfare in developing countries. The introduction by Charles Cooper deals with recent advances in the economics of innovation and diffusion of new technologies, and attempts to build a bridge between the study of technology in the industrial sectors of developed countries and the type of technology policy needed in the developing countries. Policymakers, researchers and students will welcome the clarity and breadth of this important volume which contains much original analysis and detailed information on a major issue confronting developing and developed nations alike.

This volume presents a timely recognition, warning and mapping of the fast approaching wave, or "bio-tsunami", of global socio-technical transformation, built by a much wider spectrum of converging powers, including biotechnology, new agriculture, novel foods, health, quality of life, environment, energy, sustainability, education, knowledge management, and design of smart applications. The book contains eight sections corresponding to different clusters of bioeconomic and socio-technical change, as identified by the editors' "Scanning the Horizon" foresight research; it also offers an integrated view of the future bioeconomy landscape though the convergence of several technologies that affect everyday life. The clusters offer methodologies for forecasting the future bioeconomy, and how these predictions can affect target-setting and the orientation of policies and actions to manage cultural and societal change, and achieve sustainable development in less developed areas. The book will be of interest to researchers, producers, logistics experts, policy makers, regulators, business and financial institutions, and biotechnologists (e.g. geneticists, food experts, etc.).