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Books > Professional & Technical > Biochemical engineering > Biotechnology > General
Description
Using chips composed of thousands of spots, each with the
capability of holding DNA molecules corresponding to a given gene,
DNA microarray technology has enabled researchers to measure
simultaneously gene expression across the genome. As with other
large scale genomics approaches, microarray technologies are
broadly applicable across disciplines of life and biomedical
sciences, but remain daunting to many researchers. This guide is
designed to demystify the technology and inform more biologists
about this critically important experimental technique.
.Provides a basic overview of microarray technology and available
platforms for those unfamiliar with the technology
.Includes detailed discussion of experimental design and analysis
of microarray experiments, giving first-time users valuable
information that can be tailored to their own research needs
.Provides discussion of such hot areas as ChIP (chromatin
immunoprecipitation) with hybridization to DNA arrays,
microarray-based comparative genomic hybridization (CGH), and cell
and tissue arrays
Expert author team highlights the utility of the technology using
examples from human health and disease--e.g., malaria and cancer
diagnostics.
This edited book serves as a vital resource on the contributions of
microorganisms to advances in nanotechnology, establishing their
applications in diverse areas of biomedicine, environment,
biocatalysis, food and nutrition, and renewable energy. It
documents the impacts of microorganisms in nanotechnology leading
to further developments in microbial nanobiotechnology. This book
appeals to researchers and scholars of microbiology, biochemistry
and nanotechnology.
Before the concept of history began, humans undoubtedly acquired
life benefits by discovering medicinal and aromatic plants (MAPs)
that were food and medicine. Today, a variety of available herbs
and spices are used and enjoyed throughout the world and continue
to promote good health. The international market is also quite
welcoming for MAPs and essential oils. The increasing environment
and nature conscious buyers encourage producers to produce high
quality essential oils. These consumer choices lead to growing
preference for organic and herbal based products in the world
market. As the benefits of medicinal and aromatic plants are
recognized, these plants will have a special role for humans in the
future. Until last century, the production of botanicals relies to
a large degree on wild-collection. However, the increasing
commercial collection, largely unmonitored trade, and habitat loss
lead to an incomparably growing pressure on plant populations in
the wild. Therefore, medicinal and aromatic plants are of high
priority for conservation. Given the above, we bring forth a
comprehensive volume, "Medicinal and Aromatic Plants: Healthcare
and Industrial Applications", highlighting the various healthcare,
industrial and pharmaceutical applications that are being used on
these immensely important MAPs and its future prospects. This
collection of chapters from the different areas dealing with MAPs
caters to the need of all those who are working or have interest in
the above topic.
Proteins are exposed to various interfacial stresses during drug
product development. They are subjected to air-liquid,
liquid-solid, and, sometimes, liquid-liquid interfaces throughout
the development cycle-from manufacturing of drug substances to
storage and drug delivery. Unlike small molecule drugs, proteins
are typically unstable at interfaces where, on adsorption, they
often denature and form aggregates, resulting in loss of efficacy
and potential immunogenicity. This book covers both the fundamental
aspects of proteins at interfaces and the quantification of
interfacial behaviors of proteins. Importantly, this book
introduces the industrial aspects of protein instabilities at
interfaces, including the processes that introduce new interfaces,
evaluation of interfacial instabilities, and mitigation strategies.
The audience that this book targets encompasses scientists in the
pharmaceutical and biotech industry, as well as faculty and
students from academia in the surface science, pharmaceutical, and
medicinal chemistry areas.
Biotechnology is a diverse, complex, and rapidly evolving field.
Students and experienced researchers alike face the challenges of
staying on top of developments in their field of specialty and
maintaining a broader overview of the field as a whole. This latest
volume of "Biotechnology Annual Review" comprises expert reviews on
a diverse range of topics, ranging from gene expression microarray
analysis to the use of ethnomedicines and ethnomedicinal
phytophores to treat herpes viruses. Such a diverse range of review
topics will keep biotechnologists of all levels up-to-date on the
latest in the vast field of biotechnology and deepen their
understanding of the many facets of the field as a whole.
*More than 150 figures elucidate and reinforce key points
*Inclusion of reviews of such hot-topics as arginine methylation in
health and disease
*Wide variety of coverage keeps biotechnologists up-to-date on many
facets of the field
Stephen Heywood was twenty-nine years old when he learned that
he was dying of ALS -- Lou Gehrig's disease. Almost overnight his
older brother, Jamie, turned himself into a genetic engineer in a
quixotic race to cure the incurable. His Brother's Keeper is a
powerful account of their story, as they travel together to the
edge of medicine.
The book brings home for all of us the hopes and fears of the
new biology. In this dramatic and suspenseful narrative, Jonathan
Weiner gives us a remarkable portrait of science and medicine
today. We learn about gene therapy, stem cells, brain vaccines, and
other novel treatments for such nerve-death diseases as ALS,
Alzheimer's, and Parkinson's -- diseases that afflict millions, and
touch the lives of many more.
"The Heywoods' story taught me many things about the nature of
healing in the new millennium," Weiner writes. "They also taught me
about what has not changed since the time of the ancients and may
never change as long as there are human beings -- about what
Lucretius calls 'the ever-living wound of love.'"This P.S. edition
features an extra 16 pages of insights into the book, including
author interviews, recommended reading, and more.
The book comprehensively covers the different topics of graphene
based biopolymer and nanocomposites, mainly synthesis methods for
the composite materials, various characterization techniques to
study the superior properties and insights on potential advanced
applications.The book will address and rectify the complications of
using plastics that are non-degradable and has abhorrent impact on
environment. The limitations of properties of biopolymer can be
vanquished by employing graphene as a nanomaterial. Outstanding
properties of graphene in accordance with biopolymer can be
utilized to develop applications like water treatment, tissue
engineering, photo-catalysts, super-absorbents. This is a useful
reference source for both engineers and researchers working in
composite materials science as well as the students attending
materials science, physics, chemistry, and engineering courses.
Algae are simple, primitive, heterogeneous, autotrophic, eukaryotic
or prokaryotic organisms that lead a symbiotic, parasitic or
free-living mode of life. Microalgae and macroalgae possess great
potential in various fields of application. Microalgae are
ubiquitous and extremely diverse microorganisms that can accumulate
toxic contaminants and heavy metals from wastewater, making them a
superior candidate to become a powerful nanofactory. Algae were
discovered to reduce the presence of metal ions, and afterwards aid
in the biosynthesis of nanoparticles. Since algae-mediated biogenic
nanoparticles are eco-friendly, cost-effective, high-yielding,
speedy and energy-efficient, a large number of studies have been
published on them in the last few years. This book focuses on
recent progress on the utilization of algae for the synthesis of
nanoparticles, their characterization and the possible mechanisms
involved. Bioprospecting Algae for Nanosized Materials describes
the synthesis of algal nanomaterials and its application in various
fields for sustainable development. This book outlines the
procedures to prepare phyconanomaterials, techniques to utilize the
nanomaterials, and applications in agriculture, environment and
medicine.
Cancer Nanotheranostics, Volume 2 continues the discussion of the
important work being done in this field of cancer nanotechnology.
The contents of these two volumes are explained in detail as
follows. In the first volume of Cancer Nanotheranostics, we discuss
the role of different nanomaterials for cancer therapy including
lipid-based nanomaterials, protein and peptide-based nanomaterials,
polymer-based nanomaterials, metal-organic nanomaterials,
porphyrin-based nanomaterials, metal-based nanomaterials,
silica-based nanomaterials, exosome-based nanomaterials, and
nano-antibodies. This important second volume discusses nano-based
diagnosis of cancer, nano-oncology for clinical applications,
nano-immunotherapy, nano-based photothermal cancer therapy,
nanoerythrosomes for cancer drug delivery, regulatory perspectives
of nanomaterials, limitations of cancer nanotheranostics, safety of
nanobiomaterials for cancer nanotheranostics, multifunctional
nanomaterials for targeting cancer nanotheranostics, and the role
of artificial intelligence in cancer nanotheranostics. Volume 2 is
a vital continuation of this two-volume set. Together, these two
volumes create a comprehensive and unique examination of this
important area of research.
This book aims to comprehensively summarize the current research
status of nanomaterials and cell biology. It highlights the
biological effects and biomedical applications of nanomaterials for
specific diseases, bone tissue engineering, and skeletal muscle
regeneration. It also provides the details of the biomedical
applications of nucleic acid nanomaterials in drug delivery
carriers, antimicrobial therapy, vaccine, and neurodegenerative
diseases. Therefore, this book renders the audience a better
understanding of nanomaterials along with the diverse applications
in the cell biology field from recent works to perspectives.
This book examines Ghana's use of the fingerprint biometric
technology in order to further conversations about localization
championed by technical communication scholars. Localization, in
this case, refers to the extent to which users demonstrate their
knowledge of use by subverting and reconfiguring the purpose of
technology to solve local problems. Dorpenyo argues that the
success of a technology depends on how it meets the users' needs
and the creative efforts users put into use situations. In User
Localization Strategies in the Face of Technological Breakdown,
Dorpenyo advocates studying how users of technological systems
construct knowledge about the technology and develop local
strategies to solve technological breakdowns. By analyzing
technical documents and interview transcripts, the author
identifies and advances three user localization strategies:
linguistic localization, subversive localization, and
user-heuristic experience localization, and considers how biometric
systems can become a tool of marginalization.
This book reviews the current knowledge on tunable hydrogels,
including the range of different materials and applications, as
well as the existing challenges and limitations in the field. It
covers various aspects of the material design, particularly
highlighting biological responsiveness, degradability and
responsiveness to external stimuli. In this book, readers will
discover original research data and state-of-the-art reviews in the
area of hydrogel technology, with a specific focus on biotechnology
and medicine. Written by leading experts, the contributions outline
strategies for designing tunable hydrogels and offer a detailed
evaluation of the physical and synthetic methods currently employed
to achieve specific hydrogel properties and responsiveness. This
highly informative book provides important theoretical and
practical insights for scholars and researchers working with
hydrogels for biomedical and biotechnological applications.
New technologies will have an increasing effect on prospects for
development and growth in the world economy. Technology and
Innovation in the International Economy contains extensive and
detailed assessments of two key areas of technological innovation
which present both a threat and an opportunity for developing
countries: microelectronics and biotechnology.The two major review
essays - Jeffrey James on microelectronic technology and Martin
Fransman on biotechnology - assess the impact of these new
technologies on production, trade, employment and welfare in
developing countries. The introduction by Charles Cooper deals with
recent advances in the economics of innovation and diffusion of new
technologies, and attempts to build a bridge between the study of
technology in the industrial sectors of developed countries and the
type of technology policy needed in the developing countries.
Policymakers, researchers and students will welcome the clarity and
breadth of this important volume which contains much original
analysis and detailed information on a major issue confronting
developing and developed nations alike.
This volume presents a timely recognition, warning and mapping of
the fast approaching wave, or "bio-tsunami", of global
socio-technical transformation, built by a much wider spectrum of
converging powers, including biotechnology, new agriculture, novel
foods, health, quality of life, environment, energy,
sustainability, education, knowledge management, and design of
smart applications. The book contains eight sections corresponding
to different clusters of bioeconomic and socio-technical change, as
identified by the editors' "Scanning the Horizon" foresight
research; it also offers an integrated view of the future
bioeconomy landscape though the convergence of several technologies
that affect everyday life. The clusters offer methodologies for
forecasting the future bioeconomy, and how these predictions can
affect target-setting and the orientation of policies and actions
to manage cultural and societal change, and achieve sustainable
development in less developed areas. The book will be of interest
to researchers, producers, logistics experts, policy makers,
regulators, business and financial institutions, and
biotechnologists (e.g. geneticists, food experts, etc.).
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