Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

Structural Biomaterials: Properties, Characteristics, and Selection serves as a single point of reference to digest current research and develop a deeper understanding in the field of biomaterials engineering. This book uses a materials-focused approach, allowing the reader to quickly access specific, detailed information on biomaterials characterization and selection. Relevant to a range of readers, this book provides holistic coverage of the broad categories of structural biomaterials currently available and used in medical applications, highlighting the property requirements for structural biomaterials, their biocompatibility performance and their safety regulation in key categories such as metals, ceramics and polymers. The materials science perspective of this text ensures the content is accessible even to those without an extensive background in applied medicine, positioning this text not just for students, but as an overview and reference for researchers, scientists and engineers entering the field from related materials science disciplines.

Biofertilizers, Volume One: Advances in Bio-inoculants provides state-of-the-art descriptions of various approaches, techniques and basic fundamentals of BI used in crop fertilization practices. The book presents research within a relevant theoretical framework to improve our understanding of core issues as applied to natural resource management. Authored by renowned scientists actively working on bio-inoculant, biofertilizer and bio-stimulant sciences, the book addresses the scope of inexpensive and energy neutral bio-inoculant technologies and the impact regulation has on biofertilizer utilization. This book is a valuable reference for agricultural/environmental scientists in academic and corporate environments, graduate and post-graduate students, regulators and policymakers.

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.

Millets and Pseudo Cereals is the first comprehensive resource to focus on the potential crop improvements through genetic enhancements. The choice of food crop for a region is primarily determined by the conditions of climate and soil. Once labelled as orphan crops, millets and pseudo-cereals are now known as miracle grains due to their adaptation to harsh conditions and high nutritional quality. Small millets and pseudo-cereals are now seen to occupy special niches through their ability to adapt to challenging conditions. These crops have a comparative advantage in marginal lands where they withstand stress conditions and contribute to sustainable production. They also contribute to the diversity-richness and production stability of agro-ecosystems. Millets include sorghum, pearl millet, finger millet, foxtail millet, proso millet, barnyard millet, little millet and kodo millet while the other group which are not cereals but consumed as cereals and generally referred as pseudo-cereals comprises of grain amaranths, buckwheat and chenopods. Millets and Pseudo Cereals presents current information on the genetic architecture of important economic traits and the genomic resources for gene enabled breeding. This compilation contains information on the global status, available germplasm resources, nutritional value, breeding advancements, genomics applications and sustainability of agriculture through millets and pseudo-cereals cultivation. This book is a valuable resource for those conducting research and exploring new areas for advancing crop genetic understanding.

Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science - from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology.

Improving Cereal Productivity through Climate Smart Practices is based on the presentations of the 4th International Group Meeting on "Wheat productivity enhancement through climate smart practices," and moves beyond the presentations to provide additional depth and breadth on this important topic. Focused specifically on wheat, and with chapters contributed by globally renowned pioneers in the field of cereal science, the book helps readers understand climate change and its effects on different aspects of wheat production in different parts of the world. This book will be important for those in research and industry seeking to contribute to the effective feeding of the world's population.

Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine.

3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine.

Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering.

Digital Health: Mobile and Wearable Devices for Participatory Health Applications is a key reference for engineering and clinical professionals considering the development or implementation of mobile and wearable solutions in the healthcare domain. The book presents a comprehensive overview of devices and appropriateness for the respective applications. It also explores the ethical, privacy, and cybersecurity aspects inherent in networked and mobile technologies. It offers expert perspectives on various approaches to the implementation and integration of these devices and applications across all areas of healthcare. The book is designed with a multidisciplinary audience in mind; from software developers and biomedical engineers who are designing these devices to clinical professionals working with patients and engineers on device testing, human factors design, and user engagement/compliance.

Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process-enabling targeted selection of coatings and technologies to enhance long-term implant-bone integration.

Modeling, Optimization and Control of Zinc Hydrometallurgical Purification Process provides a clear picture on how to develop a mathematical model for complex industrial processes, how to design the optimization strategy, and how to apply control methods in order to achieve desired production target. This book shares the authors' recent ideas/methodologies/algorithms on the intelligent manufacturing of complex industry processes, e.g., how to develop a descriptive framework which could enable the digitalization and visualization of a process and how to develop the controller when the process model is not available.

Computational Intelligence and Its Applications in Healthcare presents rapidly growing applications of computational intelligence for healthcare systems, including intelligent synthetic characters, man-machine interface, menu generators, user acceptance analysis, pictures archiving, and communication systems. Computational intelligence is the study of the design of intelligent agents, which are systems that act intelligently: they do what they think are appropriate for their circumstances and goals; they're flexible to changing environments and goals; they learn from experience; and they make appropriate choices given perceptual limitations and finite computation. Computational intelligence paradigms offer many advantages in maintaining and enhancing the field of healthcare.

New and Future Developments in Microbial Biotechnology and Bioengineering presents an account of recent developments and applied aspects of fungi and its metabolites for human welfare. The fungi and its metabolites are employed in diverse fields of agri-food, biochemistry, chemical engineering, diagnostics, pharmaceuticals and medical device development. The book contains chapters by the eminent researchers working with fungi and fungal metabolites who explain their importance and potential in manifold prospects. The book includes a description of various fungal metabolites and their chemistry and biotechnology.

Advances in Applied Microbiology, Volume 113, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic, with this release focusing on Gaps in the Assortment of Rapid Assays for Microorganisms of Interest to the Dairy Industry, Metal reduction and corrosion by bacterial biofilms, The microbiology of red brines, Clostridium thermocellum: a microbial platform for high-value chemical production from lignocellulose, and The zincophore system in pathogenic yeasts.

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

In the age of data science, the rapidly increasing amount of data is a major concern in numerous applications of computing operations and data storage. Duplicated data or redundant data is a main challenge in the field of data science research. Data Deduplication Approaches: Concepts, Strategies, and Challenges shows readers the various methods that can be used to eliminate multiple copies of the same files as well as duplicated segments or chunks of data within the associated files. Due to ever-increasing data duplication, its deduplication has become an especially useful field of research for storage environments, in particular persistent data storage. Data Deduplication Approaches provides readers with an overview of the concepts and background of data deduplication approaches, then proceeds to demonstrate in technical detail the strategies and challenges of real-time implementations of handling big data, data science, data backup, and recovery. The book also includes future research directions, case studies, and real-world applications of data deduplication, focusing on reduced storage, backup, recovery, and reliability.

Biocontrol and Secondary Metabolites: Applications and Immunization for Plant Growth and Protection covers established and updated research on emerging trends in plant defense signaling in, and during, stress phases. Other topics cover growth at interface as a sustainable way of life and the context of human welfare and conservation of fungi as a group of organisms. Further, the book explores induced systemic resistance using biocontrol agents and/or secondary metabolites as a milestone for sustainable agricultural production, thus providing opportunities for the minimization or elimination of the use of fungicides.

Handbook of Polymers in Medicine combines core concepts and advanced research on polymers, providing a better understanding of this class of materials in medicine. The book covers all aspects of medical polymers from characteristics and biocompatibility, to the diverse array of applications in medicine. Chapters cover an introduction to polymers in medicine and the challenges associated with biocompatibility in human tissue, polyurethane and supramolecular polymers and their specific applications in medicine, from tissue regeneration to orthopedic surgery and cancer therapeutics. This book offers an interdisciplinary approach that will appeal to researchers in a range of disciplines, including biomedical engineering, materials science, chemistry, pharmacology and translational medicine. The book will also make a useful reference for clinicians and those in medical fields who are interested in materials for medical applications, as well as R&D groups involved in medical device design.

New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Advances in Application of Fungi and Fungal Metabolites: Applications in Healthcare presents an account of recent development and applied aspects of fungi and its metabolites in the healthcare sector. Chapters are written by eminent researchers, emphasizing the incredible role of fungi and its metabolites in the field of medicine. This book offers reference material to all mycologists working on the exploration and usage of medicinal aspects of fungi and fungal metabolites.

Controlled Release Fertilizers for Sustainable Agriculture provides a comprehensive examination of precision fertilizer applications using the 4-R approach-the right amount of fertilizer at the right time to the right plant at the correct stage of plant growth. This volume consolidates detailed information on each aspect of controlled release fertilizers, including up-to-date literature citations, the current market for controlled release fertilizers and patents. Presenting the tremendous advances in experimental and theoretical studies on sustainable agriculture and related areas, this book provides in-depth insight into state-of-the-art controlled release mechanisms of fertilizers, techniques, and their use in sustainable agriculture. Conventional release mechanisms have historically meant waste of fertilizers and the adverse effects of that waste on the environment. Controlled release delivery makes significant strides in enhancing fertilizer benefit to the target plant, while protecting the surrounding environment and increasing sustainability.

Advances in Applied Microbiology, Volume 112, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas. Chapters in this new release include discussions of Microbial mercury transformation: focus on molecules and functions, Peptidoglycan Biosynthesis, Clockwork microbial worlds , Molecular engineering to improve the levels of bioproducts from agricultural and forestry waste by filamentous fungi, Multi-species Biofilms for Resource Recovery from Wastewater, Evasion of host defenses by intracellular Staphylococcus aureus, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.

Advanced and Modern Approaches for Drug Delivery explores novel approaches currently used for drug delivery, including the must up-to-date techniques and technology. The approaches discussed allow pharmaceutical scientists to design effective drug delivery systems or devices for the management and treatment of numerous diseases and conditions. Detailed information on a wide variety of subjects, including dendrimers, lipid nanostructures, solid lipid nanoparticles, stimuli-responsive smart systems, self-assembled protein-drug nanoparticles, nanoconjugate formulations, nanofibers, iontophoretic systems, microneedle systems, ultra-sound triggered systems, targeted carrier-based intracellular delivery systems, resealed erythrocyte-based systems, 3 D-printing tool, site-specific monoclonal antibodies, and bio-inspired systems are all comprehensively discussed. With contributions from those in academia and industry, this book is an excellent reference for all those needing to understand drug delivery systems.