The Economics of Biotechnology is a highly accessible book dealing with some of the most crucial issues to arise in this area. Special attention is paid to consumer, ethical and environmental concerns as well as questions relating to trade policy, intellectual property, who will receive the benefits, international development and the role of international institutions such as the WTO. The authors examine concerns arising from the application of biotechnology in the agri-food industrial complex, and many of the issues discussed also have implications for the medical and pharmaceutical aspects of biotechnology. Fundamental questions regarding the application of standard economic analysis to biotechnology are resolved using traditional neo-classical analyses as well as less mainstream methods. Through exploring a number of approaches, original and unexpected conclusions are reached. This coherent and relevant treatment of the myriad facets of biotechnology will be welcomed by academics, scholars, and economists with a specific interest in international economics or technology, international policymakers, and economic commentators.

Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing.

Phyto-pathogens are one of the dominating components which badly affect crop production. In light of the global food demand, sustainable agricultural plans utilizing agrochemicals became necessary. The role of beneficial microbes in the defense priming of host plants has been well documented. This book details new aspects of microbial-assisted plant protection and their role in agricultural production, economy, and environmental sustainability.

This book provides the first comprehensive overview of saline and alkaline soils in Latin America, known for having one of the most extensive surface of salt-affected soils in the world. It is organized along two main axes: soils and vegetation. The book discusses the occurrence of such soils in the region, focusing mainly in management strategies for their sustainable use, and it presents accounts of natural vegetation and crops in the various environments of the region. Social impacts of such conditions and ongoing projects to overcome them are considered. Likewise, the book highlights physiological mechanisms that are responsible for the negative effects these soils exert on crops and forest resources and determine vegetation distribution in them. Plant breeding challenges and new perspectives for such environments are discussed. Technologies such as irrigation and drainage are included. The readership includes soil and plant scientists, as well as policy makers.

The rapid thriving of industries, conversion of agricultural land to residential areas, habitat destruction, deforestation and use of recalcitrant synthetic substances enhanced the rate of degradation of the environment. Although there are various conventional techniques for degradation and cleaning of noxious pollutants from disturbed environs, they are energy inefficient and costly to install. Bioremediation has emerged recently as an alternative and novel approach to manage and control environmental pollutants. This volume focuses explicitly on the remediation of noxious substances in stressed environs. It includes expert-contributed chapters on bio-monitoring by way of evaluating the relationship of biota with the polluted/stressed environs, sustainable plant-based degradation of noxious pollutants, and the application of biotechnologies to achieve tailored responses. Academicians, researchers, scientists and students will find this work essential for sustainable treatment of noxious pollutants. This book also serves as a core guide for training, teaching and research in conservation biology and environmental rehabilitation.

This book joins an international and interdisciplinary group of leading experts on the biomedical, energy and environmental applications of Metal-Organic Frameworks (MOFs). The resulting overview covers everything from the environmentally friendly and scale up synthesis of MOFs, their application in green energy generation and storage, and water purification to their use as drug delivery systems, biosensors, and their association with relevant macromolecules (genes, enzymes). This book is focused on the interest of MOFs in applications such as the leading -edge environmental (energy-related) and biomedical fields. The potential of MOFs in these areas is currently progressing at a fast pace, since the wide possibilities that MOFs offer in terms of composition, topology, incorporation of active species (in their porosity, on their external surface or within the framework), and post-synthetic modifications, among others. The aim here is to provide future research goals that emphasize relevant nuances to this class of materials as a whole.

The rapidly expanding molecular biological techniques and approaches have significant impact on microbial biotechnology, hence the need for the addition of four new chapters in the third edition of this textbook - "Chapter 3: Application of 'Omics' Technologies in Microbial Fermentation", "Chapter 5: Microbial Genome Mining for Identifying Antimicrobial Targets", "Chapter 21: Bacterial Biofilm: Molecular Characterization and Impacts on Water Management" and "Chapter 23: Microbial Biomining". "Chapter 15: Transgenic Plants" has been completely revised while most of the other chapters have been thoroughly updated in this new edition.There already exist a number of excellent general textbooks on microbiology and biotechnology that deal with the basic principles of microbial biotechnology. To complement them, this book focuses on the various applications of microbial-biotechnological principles. A teaching-based format is adopted, whereby working problems, as well as answers to frequently asked questions, supplement the main text. The book also includes real life examples of how the application of microbial-biotechnological principles has achieved breakthroughs in both research and industrial production.Although written for polytechnic students and undergraduates, the book contains sufficient information to be used as a reference for postgraduate students and lecturers. It may also serve as a resource book for corporate planners, managers and applied research personnel.

The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries.

Portable Biosensors and Point-of-Care Systems describes the principles, design and applications of a new generation of analytical and diagnostic biomedical devices, characterized by their very small size, ease of use, multi-analytical capabilities and speed to provide handheld and mobile point-of-care (POC) diagnostics. The book is divided in four Parts. Part I is an in-depth analysis of the various technologies upon which portable diagnostic devices and biosensors are built. In Part II, advances in the design and optimization of special components of biosensor systems and handheld devices are presented. In Part III, a wide scope of applications of portable biosensors and handheld POC devices is described, ranging from the support of primary healthcare to food and environmental safety screening. Diverse topics are covered, including counterterrorism, travel medicine and drug development. Finally, Part IV of the book is dedicated to the presentation of commercially available products including a review of the products of point-of-care in-vitro-diagnostics companies, a review of technologies which have achieved a high Technology Readiness Level, and a special market case study of POC infusion systems combined with intelligent patient monitoring. This book is essential reading for researchers and experts in the healthcare diagnostic and analytical sector, and for electronics and material engineers working on portable sensors.

Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies.

Due to the huge quantity and diverse nature of their metabolic pathways, fungi have great potential to be used for the production of different biofuels such as bioethanol, biobutanol, and biodiesel. This book presents recent advances, as well as challenges and promises, of fungal applications in biofuel production, subsequently discussing plant pathogenic fungi for bioethanol and biodiesel production, including their mechanisms of action. Additionally, this book reviews biofuel production using plant endophytic fungi, wood-rotting fungi, fungal biocontrol agents, and gut fungi, and it investigates highly efficient fungi for biofuel production and process design in fungal-based biofuel production systems. Finally, life cycle assessment of fungal-based biofuel production systems are discussed in this volume.

In this book, Dr Quintyn considers whether genetic engineering will exacerbate social injustices and/or lead to public safety issues. As designer babies mature, will they feel a sense of superiority or pass on mutations that negatively affect future generations? Should we ignore the risk of zoonotic (animal) diseases because they offer potential benefits for reducing organ shortages? Scientific advancement, if not guided responsibly and with public input, can be detrimental to public safety.This book is unique as it encompasses many biotechnologies within the definition of biotechnology. It gives a balanced view of biotechnology: its promise as evidenced in repairing mutations (i.e., genetic editing) and its dangers evidenced in creating (unintentionally) dangerous microbes or unregulated germline editing and cloning. Additionally, this book includes animals in biotechnological research because the success, advances, techniques, and science of genetic engineering could not have occurred without using animals (and microorganisms, insects, plants) as model organisms. A comprehensive description of the CRISPR system in bacteria and the exploitation of this knowledge in creating the CRISPR/Cas9 technology is also incorporated in this read.The author's overall goal is to discuss other biotechnology that is being used to improve and put at risk the health, environment, and safety of humans, giving the book a competitive edge. Furthermore, the book provides a provocative side in challenging scientists to consider the current belief governing research and development, which is that scientific advancement and public safety create a false dichotomy.

Description
Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique.
.Provides a basic overview of microarray technology and available platforms for those unfamiliar with the technology
.Includes detailed discussion of experimental design and analysis of microarray experiments, giving first-time users valuable information that can be tailored to their own research needs
.Provides discussion of such hot areas as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
Expert author team highlights the utility of the technology using examples from human health and disease--e.g., malaria and cancer diagnostics.

This edited book serves as a vital resource on the contributions of microorganisms to advances in nanotechnology, establishing their applications in diverse areas of biomedicine, environment, biocatalysis, food and nutrition, and renewable energy. It documents the impacts of microorganisms in nanotechnology leading to further developments in microbial nanobiotechnology. This book appeals to researchers and scholars of microbiology, biochemistry and nanotechnology.

Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.

Biotechnology is a diverse, complex, and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. This latest volume of "Biotechnology Annual Review" comprises expert reviews on a diverse range of topics, ranging from gene expression microarray analysis to the use of ethnomedicines and ethnomedicinal phytophores to treat herpes viruses. Such a diverse range of review topics will keep biotechnologists of all levels up-to-date on the latest in the vast field of biotechnology and deepen their understanding of the many facets of the field as a whole.
*More than 150 figures elucidate and reinforce key points
*Inclusion of reviews of such hot-topics as arginine methylation in health and disease
*Wide variety of coverage keeps biotechnologists up-to-date on many facets of the field