Nanostructured Biomaterials for Regenerative Medicine focuses on the definition of new trends for the design of biomaterials for biomedical applications. It includes the ex novo synthesis as well as technological strategies to manipulate them into appropriate two-dimensional (2D) and three-dimensional (3D) forms, in order to impart all the main physical, chemical, structural and biological properties requested to achieve desired clinical efficacy. This book aims at offering a concise overview of innovative platforms based on nanostructured biomaterials as a function of their chemical nature - established by a consolidated material classification i.e., polymer, ceramics and metals. For each class, emerging bioinspired systems with rapid expansion in the biomedical research area and fabricated via new enabling technologies will be proposed for the use in tissue repair/regeneration and nanomedicine. This book is an essential resource for researchers, academics and professionals interested in the potential of nanostructured biomaterials for regenerative medicine.

Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology explores PGPMs (actinomycetes, bacteria, fungi and cyanobacteria) and their multidimensional roles in agriculture, including their increasing applications in sustainable agriculture. In addition to their traditional understanding and applications in agriculture, PGPMs are increasingly known as a source of nano-particles production that are gaining significant interest in their ability to provide more economically, environmentally friendly and safe technologies to crop growers. The book considers new concepts and current developments in plant growth, thus promoting microorganisms research and evaluating its implications for sustainable productivity. Users will find this to be an invaluable resource for researchers in applied microbial biotechnology, soil science, nano-technology of microbial strains, and industry personnel in these areas.

Functional Polysaccharides for Biomedical Applications examines the fundamentals and properties of these natural materials and their potential biomedical applications. With an emphasis on therapeutic and sensing applications, the book also reviews how polysaccharides can be modified for tissue engineering applications. Sections discuss the basics of polysaccharides, give an overview of the potential applications, look at novel materials and technologies for use in tissue regeneration and therapeutics, and detail current biomedical applications. With a strong focus on materials, engineering and applications, this book is a valuable resource for those with an interest in harnessing the biomedical potential of natural polymers.

Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry.

Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter.

Materials for Biomedical Engineering: Absorbable Polymers provides a detailed and comprehensive review of recent progress in absorbable biopolymers and their impact on biomedical engineering. The book's main focus lies in their classification, processing, properties and performance, biocompatibility, and their applications in tissue engineering, drug delivery, bone repair and regenerative medicine. The most up-to-date methods used to obtain such polymers and how to improve their properties is discussed in detail. This book provides readers with a comprehensive and updated review of the latest research in the field of absorbable polymers for biomedical applications.

Biomaterials for Skin Repair and Regeneration examines a range of materials and technologies used for regenerating or repairing skin. With a strong focus on biomaterials and scaffolds, the book also examines the testing and evaluation pathway for human clinical trials. Beginning by introducing the fundamentals on skin tissue, the book goes on to describe contemporary technology used in skin repair as well as currently available biomaterials suitable for skin tissue repair and regeneration. Skin tissue engineering and the ideal requirements to take into account when developing skin biomaterials are discussed, followed by information on the individual materials used for skin repair and regeneration. As evaluation of biomaterials in animal models is mandatory before proceeding into human clinical trials, the book also examines the different animal models available. With a strong focus on materials, engineering, and application, this book is a valuable resource for materials scientists, skin biologists, and bioengineers with an interest in tissue engineering, regeneration, and repair of skin.

Genetic Engineering and Genome Editing for Zinc Biofortification of Rice provides the first single-volume, comprehensive resource on genetic engineering approaches, including novel genome editing techniques, that are carried out in rice, a staple crop for much of the world's population. Dietary zinc deficiency can lead to negative health outcomes, including increased risk of stunting, respiratory diseases, diarrhea, mortality during childhood, and preterm births in pregnancy. By providing a complete view of the need for zinc biofortification in rice, sections in this book discuss state-of-the-art scientific advances, and then go further, placing them in their proper scientific, regulatory and socioeconomic contexts. While zinc biofortification can be achieved through conventional breeding, genetic engineering and agronomic practices, this is the first reference to bring all the latest insights and understanding to a comprehensive resource that is based on real-world experience and targeted applications.

Advances and Applications of Partitioning Bioreactors, Volume 54, presents an updated reference in the field of partitioning bioreactors, addressing the relevance of kinetic determination, cell deactivation and transport phenomena from an engineering point-of-view. Topics covered in this new release include Mass transport phenomena in partitioning bioreactors, Modelling and design of partitioning bioreactors, Population balances for partitioning bioreactors, Solid-liquid partitioning bioreactors for industrial wastewater treatment, Multiphase bioreactors in the Food Industry, Multiphase bioreactors in the pharmaceutical industry, Biological treatment of gas pollutants in partitioning bioreactors, Hydrocarbon biodegradation using airlift bioreactors, and more.

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy offers an up-to-date perspective on recent research findings regarding the application and use of these materials for disease treatment and prevention. Various types of currently investigated bioactive materials, including therapeutic nanostructures and antimicrobial hydrogels are discussed, as are their properties, impact and future role in therapeutic applications. The book will be extremely useful for new researchers who want to explore more information on the use of bioactive materials or for more experienced researchers who are interested in new trends and specific applications.

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

Microbial Biofilms: Challenges and Advances in Metabolomics Study, a volume in the Advances in Biotechnology and Bioengineering series, covers the metabolomic characteristics of bacterial biofilms and examines the techniques used in the analysis of the metabolomics of the biofilm, its formation and related infections. The book covers the metabolomics study of various types of biofilms and details new strategies in targeting metabolic pathways for inhibiting the biofilm. The book also details various types of metabolomics studies of biofilm formation such as oral biofilm and biofilm by various nosocomial organisms. Recent advancements on various aspects of metabolomics studies pertaining to biofilms, related infections, their pathogenesis, and present-day treatment strategies are also covered. This book will be a helpful resource to scientists and researchers engaged in studying the formation of biofilms based upon the metabolomics changes taking place within the organism and to clinicians and health professionals interested in chronic infections caused by the biofilm and related metabolomics studies.

Functional Nanostructured Interfaces for Environmental and Biomedical Applications provides an overview on the characteristics of nanostructured interfaces and their processing technologies for a wide range of applications in the sensing, photocatalytic and bioengineering areas. The book focuses on the fundamentals of multifunctional nanostructured interfaces and their associated technologies, including versatile technologies, such as colloidal lithography, scanning probe techniques and laser nanostructuring, which can be used to obtain multifunctional 2D and 3D nanotextured interfaces. The book provides multidisciplinary chapters, summarizes the current status of the field, and covers important scientific and technological developments made over past decades. As such, it is an invaluable reference to those working in the design of novel nanostructured materials.

Metals for Biomedical Devices, Second Edition, has been fully updated and builds upon the success of its first edition, discussing the latest techniques in metal processing methods and the behavior of this important material. Initial chapters review the current status and selection of metals for biomedical devices. Subsequent chapters cover mechanical behavior, degradation and testing, corrosion, wear testing and biocompatibility, the processing of metals for biomedical applications, including topics such as forging metals and alloys, surface treatment, coatings and sterilization. Chapters in the final section discuss the clinical applications of metals, such as cardiovascular, orthopedic and new generation biomaterials. With its distinguished editor and team of expert contributors, this book is a standard reference for materials scientists, researchers and engineers working in the medical devices industry and academia.

Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities.

Nano-Biopesticides Today and Future Perspectives is the first single-volume resource to examine the practical development, implementation and implications of combining the environmentally aware use of biopesticides with the potential power of nanotechnology. While biopesticides have been utilized for years, researchers have only recently begun exploring delivery methods that utilize nanotechnology to increase efficacy while limiting the negative impacts traditionally seen through the use of pest control means. Written by a panel of global experts, the book provides a foundation on nano-biopesticide development paths, plant health and nutrition, formulation and means of delivery. Researchers in academic and commercial settings will value this foundational reference of insights within the biopesticide realm.

Effect of High-Pressure Technologies on Enzyme: Science and Applications provides a deep, practical discussion of high-pressure processing (HPP) and high-pressure homogenization (HPH) technologies and biochemical approaches, applied across research and industry, with applications ranging from food to pharmaceuticals and commercial enzyme production. Early chapters discuss foundational aspects of HPP and HPH approaches; the science of enzyme modification; and basic aspects of enzyme activity, stability, and structure as studied in biochemical processes. Later chapters consider the effect of HPP and HPH technologies and their mechanisms of controlling enzyme modification to improve enzyme performance for chosen applications. Special attention is paid to the application of HPP and HPH technologies and enzyme modifications in food processing, microbial enzyme modification, drug discovery, and production of other commercial enzymes, as well as the challenges of undesirable enzyme inactivation. The final chapter discusses future directions of the field and technologies, and expanded applications.

The Impact of Nanoparticles on Agriculture and Soil, part of the Nanomaterials-Plant Interaction series, contributes the most recent insights into understanding the cellular interactions of nanoparticles in an agricultural setting, focusing on current applications and means of evaluating future prospects. In order to ensure and improve the biosafety of nanoparticles, it is a primary concern to understand cellular bioprocess like nanomaterial's cellular uptake and their influence on cellular structural, functional and genetic components. This book addresses these and other important aspects in detail along with showcasing their applications in the area of agriculture. With an international team of authors, and experienced editors, this book will be valuable to those working to understand and advance nanoscience to benefit agricultural production and human and environmental welfare. In-depth knowledge of these bioprocess will enable researchers to engineer nanomaterials for enhanced biosafety.

Ozonation and Biodegradation in Environmental Engineering: Dynamic Neural Network Approach gives a unified point-of-view on the application of DNN to estimate and control the application of ozonation and biodegradation in chemical and environmental engineering. This book deals with modelling and control design of chemical processes oriented to environmental and chemical engineering problems. Elimination in liquid, solid and gaseous phases are all covered, along with processes of laboratory scale that are evaluated with software sensors and controllers based on DNN technique, including the removal of contaminants in residual water, remediation of contaminated soil, purification of contaminated air, and more. The book also explores combined treatments using both ozonation and biodegradation to test the sensor and controller.

Nanotechnology in Herbal Medicine: Applications and Innovations details how nanomaterials can be utilized to improve the therapeutic mechanisms and key properties of herbal drugs. This book guides the reader through the preparation, properties, applications, benefits and challenges of herbal nanoformulations, helping them solve fundamental and applied problems in the area of novel herbal medicines and drug delivery systems. Herbal drugs play a large role in traditional medicines, which are actively used by many cultures across the globe for the treatment of various illnesses and injuries. Despite their widespread use, herbal medicines may lead to possible health risks due to the lack of information on the chemical composition and permitted dosage.

Alumina Ceramics: Biomedical and Clinical Applications examines the extraordinary material, Alumina, and its use in biomedicine and industry. Sections discuss the fundamentals of Alumina Ceramics, look at the various industrial applications, and examine a variety of medical applications. Readers will find this to be an invaluable and unique resource for researchers, clinical professionals, engineers, and advanced level students. Alumina ceramics are a leading biomaterial used for specialist medical applications, such as bionic implants and tissue engineering, and the only biomaterial commercially viable for use as bearings for orthopedic hip replacements. As such, this book is a timely resource on the topics discussed.

Natural Gums: Extraction, Properties, and Applications provides thorough, methodical coverage of a range of natural gums. These naturally forming polysaccharides or complex carbohydrates offer advantageous properties and a range of possible applications. The book begins by introducing fundamental knowledge regarding natural gums, including structures and properties, functionalization, gelatin behavior, and characterization techniques. Subsequent sections of the book provide in-depth chapters, each guiding the reader through the extraction, properties and applications of a specific gum type, covering plant-based, animal-based, microbial-based, and marine-based natural gums. Finally, the future potential of natural gums, and their implications in a circular economy approach, are considered. This is an informative resource for researchers and advanced students in bio-based materials, polymer science, chemistry, bioengineering, materials science, and food science, as well as industrial scientists and R&D professionals with an interest in natural gums and bio-based materials for advanced applications.