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Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering.
Storing Digital Binary Data into Cellular DNA demonstrates how current digital information storage systems have short longevity and limited capacity, also pointing out that their production and consumption of data exceeds supply. Author Rocky Termanini explains the DNA system and how it encodes vast amounts of data, then presents information on the emergence of DNA as a storage technology for the ever-growing stream of data being produced and consumed. The book will be of interest to a range of readers looking to understand this game-changing technology, including researchers in computer science, biomedical engineers, geneticists, physicians, clinicians, law enforcement and cybersecurity experts.
An important overview of the state of the art in naturally occurring antimycotics!Here is a comprehensive and innovative examination of the antimycotic potential of essential plant oils and extracts against fungal infections affecting humans, animals, plants, and foodstuffs. Plant-Derived Antimycotics emphasizes the antimycotic activity of plants found in Central America, India, Nepal, Fiji, and China--areas rich in phyto-diversity and traditional botanical/medical knowledge.From editor M.K. Rai: "Since the inception of human civilization men have been using herbs against various mycotic infections. In the recent past, several antimycotic agents have been introduced into the market due to their rapid curative properties. Still, the quest for new antifungal agents of a fungicidal rather than fungistatic nature continues. Furthermore, there has been a dramatic increase in the new spectrum of fungal infections known as opportunistic fungal pathogens. Consequently, plant-derived antimycotics are gaining importance, being natural, cheaper, safer, eco-friendly, and within the reach of the common man."With a distinguished list of contributors from around the world, Plant-Derived Antimycotics explores: antifungal compounds that strengthen plant-defense systems traditional herbs that have revealed their antifungal properties newer, faster methods of screening and evaluating antifungal drugs natural antimycotics derived from plants in Croatia, South America, South Africa, China, India, and Fiji the mechanism of herbal antimycotic action the diversity of antimycotic efficacy in Asteraceous and Meliaceous plants new bioactive antifungal molecules Plant-Derived Antimycotics is an essential reference for pharmacologists, microbiologists, clinical mycologists, oncologists, immunologists, drug manufacturers, botanists and ethnobotanists, phytochemists, herbalists, and everyone searching for a natural remedy for the new spectrum of opportunistic fungal infections generated by the immunocompromising difficulties encountered by AIDS and cancer patients. Color illustrations, photographs, charts, tables, and graphs make the information easier to absorb and understand.
ODE/PDE Analysis of Antibiotic/Antimicrobial Resistance: Programming in R presents mathematical models for antibiotic/antimicrobial resistance based on ordinary and partial differential equations (ODE/PDEs). Sections cover the basic ODE model, the detailed PDE model that gives the spatiotemporal distribution of four dependent variable components, including susceptible bacteria population density, resistant bacteria population density, plasmid number, and antibiotic concentration. The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. As such, formal mathematics is minimized and no theorems and proofs are required. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs that is implemented with finite differences. Routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. Routines can then be applied to variations and extensions of the antibiotic/antimicrobial models, such as changes in the ODE/PDE parameters (constants) and the form of the model equations.
3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine.
Advances in Applied Microbiology, Volume 112, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas. Chapters in this new release include discussions of Microbial mercury transformation: focus on molecules and functions, Peptidoglycan Biosynthesis, Clockwork microbial worlds , Molecular engineering to improve the levels of bioproducts from agricultural and forestry waste by filamentous fungi, Multi-species Biofilms for Resource Recovery from Wastewater, Evasion of host defenses by intracellular Staphylococcus aureus, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.
Computational Intelligence and Its Applications in Healthcare presents rapidly growing applications of computational intelligence for healthcare systems, including intelligent synthetic characters, man-machine interface, menu generators, user acceptance analysis, pictures archiving, and communication systems. Computational intelligence is the study of the design of intelligent agents, which are systems that act intelligently: they do what they think are appropriate for their circumstances and goals; they're flexible to changing environments and goals; they learn from experience; and they make appropriate choices given perceptual limitations and finite computation. Computational intelligence paradigms offer many advantages in maintaining and enhancing the field of healthcare.
The second volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 2: Typical AIEgens Design, the editors address the design and synthesis of typical AIEgens that have made significant contributions to aggregation-induced emission research. Recent advances in the development of aggregation-induced emission systems are discussed and the book covers novel aggregation-induced emission systems in small molecule organogels, polymersomes, metal-organic coordination complexes and metal nanoclusters. Readers will also discover: A thorough introduction to the synthesis and applications of tetraphenylpyrazine-based AIEgens, AIEgens based on 9,10-distyrylanthracene, and the Salicylaldehyde Schiff base Practical discussions of aggregation-induced emission from the sixth main group and fluorescence detection of dynamic aggregation processes using AIEgens Coverage of cyclic triimidazole derivatives and the synthesis of multi-phenyl-substituted pyrrole based materials and their applications Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.
The third volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 3: Emerging Applications, the editors address the applications of AIEgens in several fields, including bio-imaging, fluorescent molecular switches, electrochromic materials, regenerative medicine, detection of organic volatile contaminants, hydrogels, and organogels. Topics covered include: AIE-active emitters and their applications in OLEDs, and circularly polarized luminescence of aggregation-induced emission materials AIE polymer films for optical sensing and energy harvesting, aggregation-induced electrochemiluminescence, and mechanoluminescence materials with aggregation-induced emission Dynamic super-resolution fluorescence imaging based on photoswitchable fluorescent spiropyran Visualization of polymer microstructures Self-assembly of micelle and vesicles New strategies for biosensing and cell imaging Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.
New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Developments in Trichoderma Research covers topics on-Trichoderma biodiversity, strain improvement and related researches in bioprocess technology, chemical engineering, bioremediation process, secondary metabolite production, Protein production, plant disease resistance and biocontrol technology. This book includes unique compilations of different chapters with emerging issues in the area of Trichoderma research and its related importance in the Biochemical-Industry-Agri-Food sector.
The marine environment has been, and continues to be, a fruitful source of novel chemical compounds that are not found in terrestrial and freshwater organisms. Many of these substances show potential biomedical applications, which could lead to development of new pharmaceutical products. Research on the utilization of natural products from marine organisms is growing by leaps and bounds; one important reason why being that, investigators, through new diving technologies, are becoming able to explore at greater depths. Studies of these marine natural products include investigations of neuronal membrane-active toxins, ion channel blockers, antitumor and antiviral agents, and anti-inflammatory molecules. This volume is the sixth in the ongoing series.
Published in 1988: It is the purpose of this book to outline and detail the many steps which are involved in bringing a fermentation product to market.
This work describes the essential steps in the development of biocatalytic processes from concept to completion. This integrated text combines the fundamentals of biocatalysis with technological experience and in-depth commercial case studies. The book starts with an introductory look at this history and present scope of biocatalysis, followed by overviews of: applications of specific enzymes; bioprocess case studies; biocatalyst selection and production; enzyme performance - activity and stability; non-conventional media - aqueous/organic biphasic, organic, gaseous media; immobilization; protein engineering and metabolic engineering; process concepts; bioreactor selection and design; patents; and commercial and financial aspects. Written by industrial and academic experts, this world is intended for the bookshelf of anyone teaching biocatalysis or working in the chemical, food, manufacturing of pharmaceutical industries who is seeking to exploit the potential of biocatalysts.
Protein engineering has proved to be one of the more fruitful
technological approaches in biotechnology, being both very powerful
and able to generate valuable intellectual property. This book aims
to present examples in which the application of protein engineering
has successfully solved problems arising in industrial
biotechnology. There is a section on its use to enhance
purification of recombinant proteins. The use of protein
engineering to modify the activity or the stability of industrial
enzymes from lipases to proteases, from carboxypeptidases to
glucanases and glucosidases, and from pectin modifying enzymes to
enzymes able to degrade recalcitrant compounds is extensively
covered. It is shown how areas as diverse as agrofood technology,
fine chemistry, detergents, bioremediation and biosensors receive
significant contributions from protein and solvent engineering.
Heterosis and Hybrid Seed Production in Agronomic Crops discusses how heterosis or "hybrid vigor" has played a major role in improving crop productivity and quality in order to feed the ever-increasing human population, particularly in developing countries. Plant breeders, agronomists, seed producers, and farmers will discover why the development of hybrids in the world's major food crops and why the methods of hybrid seed production are critical for achieving this goal. This landmark book deals with heterosis and hybrid seed production of major agronomic crops such as wheat, rice, maize, sorghum, cotton, sunflower, and rapeseed. Through Heterosis and Hybrid Seed Production in Agronomic Crops, you will discover valuable information on hybrid seed production methods that is not available in any other single volume. This unique book contains relevant and essential information about important procedures to help increase crop yield, including: methods for derivingsecond cycle inbred lines for hybrid maize possibilities for hybrid seed production in wheat techniques of hybrid sorghum seed production production of hybrid seeds using male sterile lines of cotton agronomic management in seed production plots of sunflower seed production technology of hybrid rapeseed advances in hybrid seed production technology of rice in ChinaHeterosis and Hybrid Seed Production in Agronomic Crops gives you a global perspective on essential food crops in all parts of the world. This informative guide will help you use hybrid seed production methods with important agricultural crops and increase the quality of these vital and essential food sources.
Attitudes to GM crops continue to generate tension, even though they have been grown commercially for over 20 years. Negative sentiment towards their development limits their adoption in Western countries, despite there being no evidence of harm to human health. These unfounded concerns about genetically modified crops have also inhibited uptake in many countries throughout Africa and Asia, having a major impact on agricultural productivity and preventing the widespread cultivation of potentially life-saving crops. GM Crops and the Global Divide traces the historical importance that European attitudes to past colonial influences, aid, trade and educational involvement have had on African leaders and their people. The detrimental impact that these attitudes have on agricultural productivity and food security continues to be of growing importance, especially in light of climate change, drought and the potential rise in sea levels - the effects of which could be mitigated by the cultivation of GM and gene-edited crops. Following on from her previous books Genes for Africa, GM Crops: The Impact and the Potential and Food for Africa, Jennifer Thomson unravels the reasons behind these negative attitudes towards GM crop production. By addressing the detrimental effects that anti-GM opinions have on nutrition security in developing countries and providing a clear account of the science to counter these attitudes, she hopes to highlight and ultimately bridge this global divide.
Biotechnology: Quality Assurance and Validation provides a practical, detailed discussion of what issues Quality Assurance and Quality Control need to identify for effective control in the preparation of biotechnology products. The book presents a series of topics that define some of the unique challenges facing biotechnology companies in producing biopharmaceutical products. The topics selected address quality and validation issues, starting with the cryopreservation of cell lines through the filling and finishing of the product. It includes a validation guide, a clear presentation of how to use filtration effectively, a synoptic view of cleaning procedures, and much more.
All the information necessary to set up and run a tissue culture facility is provided in this introductory book.; ; Includes an overview of all the basic tissue culture techniques and describes in detail both the theoretical background and the practical a
This book brings together contributions from leading scientists, academics, and experts from the oil and gas industry to discuss microbial-related problems faced by the industry and how bioinformatics and an interdisciplinary scientific approach can address these challenges. Microbial Bioinformatics in the Oil and Gas Industry: Applications to Reservoirs and Processes presents the major industrial problems caused by microbes (e.g., souring, biocorrosion) as well as the beneficial activities (e.g., biofuels, bioremediation). FEATURES Offers a detailed description of how bioinformatics has advanced our understanding of numerous issues in the oil and gas industry Covers cases from geographically diverse oil fields, laboratories, and research groups Contains fundamentals and applied information of relevance to the oil and gas sector Presents contributions from a team of international experts across industry and academia With its cross-disciplinary approach, this comprehensive book provides microbial ecologists, molecular biologists, operators, engineers, chemists, and academics involved in the sector with an improved understanding of the significance of microbial bioinformatics applications in the oil and gas industry.
Predictive control is a powerful tool in dealing with those processes with large time delays. Generalized Predictive Control (GPC) is the most popular approach to the subject, and this text discusses the application of GPC starting with the concept of long-range predictive control and its need in medicine (particularly automated drug deliveries). The concept of adaptation is also emphasized with respect to patient-to-patient parameter variations. Subsequent chapters discuss interactions, comparisons and various aspects of GPC. The book concludes by putting into perpective the generic nature of the architecture built around GPC and which provides model-based fault diagnosis with control.
This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications. Features summary tables presenting at-a-glance information on practices of recombinant DNA methodologies! Recombinant DNA Principles and Methodologies discusses basic and advanced topics requisite to the employment of recombinant DNA technology, such as -plasmid biology -nucleic acid biochemistry -restriction enzymes -cloning strategies -gel electrophoresis -southern and northern blotting -preparation of probes -phage lambda biology -cosmids and genome analysis -cloned gene expression -polymerase chain reaction -conventional and automated DNA sequencing -site-directed mutagenesis -and more! Elucidating the material with over 2250 edifying references, equations, drawings, and photographs, this state-of-the-art resource is a valuable hands-on guide for molecular and cell biologists, biochemists, bioprocess technologists, applied and industrial microbiologists, virologists, geneticists, chemical engineers, and upper-level undergraduate and graduate students in these disciplines.
From Biofiltration to Promising Options in Gaseous Fluxes Biotreatment: Recent Developments, New Trends, Advances, and Opportunities provides an overview on the biological tools used for the treatment of the gaseous fluxes, with emphasis on traditional and perspective options, opening new horizons for research and implementation in practice. It is known that air pollution is an emergent global issue and a priority within the international environmental programs. Moreover, technologies based on biological methods are significantly contributing to the sustainable development concept. Thus this book provides tools for solving air pollution issues in a sustainable manner. These issues can be solved at different levels (e.g., "end-of-pipe" gaseous streams, indoor/outdoor air, closed environments), which can be approached by the different biotechniques presented in the book, from classical biofiltration techniques (part 1) to phytotreatment and microalgae-based techniques (part 2). Although all options have their particularities that make them special for certain applications, a special attention is drawn to the potential of the last one, which offers multiple possibilities for biomass valorization. Scientists from worldwide with relevant experience in their field have been contributed to the development of this book.
Stem cells, characterized by the ability to both self-renew and to generate diff- entiated functional cell types, have been derived from the embryo and from va- ous sources of the postnatal animals and human. The recent advances in stem cell research have led to a better understanding of self-renewal, maintenance, and diff- entiation of both embryonic and somatic stem cells. This has significantly increased our knowledge of cellular and developmental biology in general and will certainly continue to do so for a long time to come. Moreover, given their role in maintaining and replenishing tissues, stem cells represent a potential means of restoring tissue function and thereby treating the root cause of degenerative disease. Therefore, in parallel, we need to improve our cognizance of the challenges involved in applying stem cells in clinical settings. The current chapters highlight both of these aspects: that of understanding the "actual" and that of developing the "possible. " In recognition of the growing excitement and potential of stem cells as models for both the advancement of basic science and future clinical applications, I felt it timely to edit this book in which forefront investigators would provide new findings for the use of stem cells to study various lineages and tissue types and some app- cations.
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