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Presents easy-to-read chapters Information is presented in a very accessible and logical format Identifies and explores biotechnological approaches for environmental protection Encompasses biodegradation of hazardous contaminants, biotechnology in waste management, nanotechnology and issues in environmental biotechnology research
The book traces the roots of plant biotechnology from the basic sciences to current applications in the biological and agricultural sciences, industry, and medicine. Providing intriguing opportunities to manipulate plant genetic and metabolic systems, plant biotechnology has now become an exciting area of research. The book vividly describes the processes and methods used to genetically engineer plants for agricultural, environmental and industrial purposes, while also discussing related bioethical and biosafety issues. It also highlights important factors that are often overlooked by methodologies used to develop plants' tolerance against biotic and abiotic stresses and in the development of special foods, bio-chemicals, and pharmaceuticals. The topics discussed will be of considerable interest to both graduate and postgraduate students. Further, the book offers an ideal reference guide for teachers and researcher alike, bridging the gap between fundamental and advanced approaches.
The basic concept of this book is to examine the use of innovative methods augmenting traditional plant breeding towards the development of new crop varieties under different environmental conditions to achieve sustainable food production. This book consists of two volumes: Volume 1 subtitled Breeding, Biotechnology and Molecular Tools and Volume 2 subtitled Agronomic, Abiotic and Biotic Stress Traits. This is Volume 1 which consists of 21 chapters covering domestication and germplasm utilization, conventional breeding techniques and the role of biotechnology. In addition to various biotechnological applications in plant breeding, it includes functional genomics, mutations and methods of detection, and molecular markers. In vitro techniques and their applications in plant breeding are discussed with an emphasis on embryo rescue, somatic cell hybridization and somaclonal variation. Other chapters cover haploid breeding, transgenics, cryogenics and bioinformatics.
Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. The book follows a sequential order, beginning with the current technical state-of-the-field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long-acting therapeutic approaches. The book goes on to describe established and novel long-acting systems, with a focus on the materials used to prepare these systems and their biocompatibility. Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field.
Cognitive Models for Sustainable Environment reviews the fundamental concepts of gathering, processing and analyzing data from batch processes, along with a review of intelligent and cognitive tools that can be used. The book is centered on evolving novel intelligent/cognitive models and algorithms to develop sustainable solutions for the mitigation of environmental pollution. It unveils intelligent and cognitive models to address issues related to the effective monitoring of environmental pollution and sustainable environmental design. As such, the book focuses on the overall well-being of the global environment for better sustenance and livelihood. The book covers novel cognitive models for effective environmental pollution data management at par with the standards laid down by the World Health Organization. Every chapter is supported by real-life case studies, illustrative examples and video demonstrations that enlighten readers.
Modern Practical Healthcare Issues in Biomedical Instrumentation describes the designs, applications and principles of several medical devices used in hospitals and at home. The book presents practical devices that can potentially be used for healthcare purposes. Sections cover the use of biosensors to monitor the physiological properties of the human body, focusing on devices used to evaluate, measure and manipulate the biological system, and highlighting practical devices that can potentially be used for healthcare purposes. It is an excellent resource for undergraduate, graduate and post-graduate students of biomedical engineering.
For many years the use of chemical agents such as pesticides and
herbicides has been effective in controlling the many varieties of
pests that infest both agricultural crops and backyard gardens.
However, these pests are gradually becoming resistant to these
agents, because the agents themselves are acting as selective
factors making the pests better and better able to resist and
persist. As a result, the use of biological controlling agents is
Basic Laboratory Methods for Biotechnology, Third Edition is a versatile textbook that provides students with a solid foundation to pursue employment in the biotech industry and can later serve as a practical reference to ensure success at each stage in their career. The authors focus on basic principles and methods while skillfully including recent innovations and industry trends throughout. Fundamental laboratory skills are emphasized, and boxed content provides step by step laboratory method instructions for ease of reference at any point in the students' progress. Worked through examples and practice problems and solutions assist student comprehension. Coverage includes safety practices and instructions on using common laboratory instruments. Key Features: Focuses on basic principles and methods to provide students with the knowledge needed to begin a career in the Biotechnology industry. Describes fundamental laboratory skills. Includes laboratory scenario-based questions that require students to write or discuss their answers to ensure they have mastered the chapter content. Updates reflect recent innovations and regulatory requirements to ensure students stay up to date. Tables, a detailed glossary, practice problems and solutions, case studies and anecdotes provide students with the tools needed to master the content.
Abiotic Stress and Legumes: Tolerance and Management is the first book to focus on the ability of legume plants to adapt effectively to environmental challenges. Using the -omic approach, this book takes a targeted approach to understanding the methods and means of ensuring survival and maximizing the productivity of the legume plant by improving tolerance to environmental /abiotic stress factors including drought, temperature change, and other challenges. The book presents a comprehensive overview of the progress that has been made in identifying means of managing abiotic stress effects, specifically in legumes, including the development of several varieties which exhibit tolerance through high yield using transcriptomic, proteomic, metabolomic and ionomic approaches. Further, exogenous application of various stimulants such as plant hormones, nutrients, sugars, and polyamines has emerged as an alternative strategy to improve productivity under these environmental challenges. Abiotic Stress and Legumes: Tolerance and Management examines these emerging strategies and serves as an important resource for researchers, academicians and scientists, enhancing their knowledge and aiding further research.
DNA sequence specificity is a sub-specialty in the general area of
molecular recognition. This area includes macromolecular-molecular
interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g.,
triple strands), and ligand-DNA interactions (e.g., drug-DNA). It
is this latter group of DNA sequence specificity interactions that
is the subject of Volumes 1 and 2 of "Advances in DNA Sequence
Specific Agents." As was the case for Volume 1, Part A also covers
methodology, but in Volume 2 we include calorimetric titrations,
molecular modeling, X-ray crystallographic and NMR structural
studies, and transcriptional assays. Part B also follows the same
format as Volume 1 and describes the sequence specificities and
covalent and noncovalent interactions of small ligands with
The only book of its kind, Crystalline Bacterial Cell Surface
Proteins assembles present-day understanding of the occurrence,
structure, chemistry, genetics, assembly, function, and application
potential of S-layers. The chapters are designed to stand
independent of each other and provide a complete survey of the
different topics in S-layer research. This book is intended to
stimulate further development in basic and applied S-layer
Microbial Extremozymes: Novel Sources and Industrial Applications is a unique resource of practical research information on the latest novel sources and technologies regarding extremozymes in bioremediation, waste management, valorization of industrial by-products, biotransformation of natural polymers, nutrition, food safety and diagnosis of disease. The book's broad knowledge and varying applications are useful to the food industry, dairy industry, fruit and vegetable processing, and baking and beverages industries, as well as the pharmaceutical and biomedical industries. This is a concise, all-encompassing resource for a range of scientists needing knowledge of extremozymes to enhance and research. Furthermore, it provides an updated knowledge of microbial enzymes isolated from extreme environments (temperatures, etc.) and their biotechnological applications. It will be useful to researchers, scientists and students in enzyme research. In addition, users from the dairy and baking industries will benefit from the presented content.
- Provides updated and detailed information about bioinformatics for human genomics research - Brings information from multiple areas of bioinformatics in one place - Facilitates application of key computational methods in human genomics research
Research powers innovation and technoscientific advance, but it is due for a rethink, one consistent with its deeply holistic nature, requiring deeply human nurturing. Research is a deeply human endeavor that must be nurtured to achieve its full potential. As with tending a garden, care must be taken to organize, plant, feed, and weed-and the manner in which this nurturing is done must be consistent with the nature of what is being nurtured. In The Genesis of Technoscientific Revolutions, Venkatesh Narayanamurti and Jeffrey Tsao propose a new and holistic system, a rethinking of the nature and nurturing of research. They share lessons from their vast research experience in the physical sciences and engineering, as well as from perspectives drawn from the history and philosophy of science and technology, research policy and management, and the evolutionary biological, complexity, physical, and economic sciences. Narayanamurti and Tsao argue that research is a recursive, reciprocal process at many levels: between science and technology; between questions and answer finding; and between the consolidation and challenging of conventional wisdom. These fundamental aspects of the nature of research should be reflected in how it is nurtured. To that end, Narayanamurti and Tsao propose aligning organization, funding, and governance with research; embracing a culture of holistic technoscientific exploration; and instructing people with care and accountability.
Gene probes, whether RNA or DNA, have played a central role in the rapid development of molecular biology. The wide variety of applications is matched by a considerable diversity in the methods used for generating probes, a complete account of which would be very difficult to make. Instead, this second volume in the series combines a selection of newer gene probe procedures with a review of the most important established methods, together with some examples of the ways in which gene probes can be applied. In doing so, the book aims to act not only as an introductory manual for newcomers to the field, but also as a means of broadening the horizons of existing researchers.
Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.
Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.
Nanobiotechnology for Sustainable Bioenergy and Biofuel Production provides insights into the most recent innovations, trends, concerns and challenges in the production of biofuels. This book highlights a number of key research topics and practical applications of modern nanomaterials and nanocomposite-driven enzyme biotechnology for biofuels production, including the advances in the nanoscaffolds design (nanomaterials support) for immobilizing bioenergy producing enzymes (nanobiocatalyst system), the recent trends in biomass processing (untreated/treated agriculture and food waste, grasses, algal, etc.) using advanced nanobiocatalysts for biofuels production and the scale-up study of bioenergy production using nanomaterials immobilized enzymes and biofuel harvesting using nanomaterials. At the outset of new nanobiotechnology applications in biofuel production, there is a need for a new resource in the bioenergy field. This book delivers an overview of the contributions of biofuel production and the most up-to-date advances in nanobiotechnology to a diverse audience ranging from post-graduate students to researchers in biochemical engineering, biotechnology, bioremediation and environmental studies and pharmaceutical professionals. Key Features * Outlines the most recent nanobiotechnological advances in biofuels and bioenergy for biofuels productions * Covers biodiesel, bioethanol, biomethane, biohydrogen, biorefineries and biofuel harvesting using nanomaterials * Explains the scale-up nanobiotechnological study of biofuel production at the bioreactor level
Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.
Tailor-Made and Functionalized Biopolymer Systems: For Drug Delivery and Biomedical Applications covers the design and application of these functionalized and tailor-made biopolymers and biopolymer systems intended for drug delivery and biomedical applications. Various concepts, design protocols and biomedical applications of tailor-made biopolymer systems are covered, guiding the reader from theoretical knowledge to practical application. Authored by an array of experts from global institutions, this book offers an interdisciplinary approach to how tailor-made biopolymers lead to novel drug delivery and treatment solutions. This will be a useful reference to a broad audience, including biomedical engineers, materials scientists, pharmacologists and chemists.
Bioleaching of chalcopyrite is always a challenge and research hotspot. The low copper extraction and dissolution kinetics restricted the industrial application of chalcopyrite bioleaching. To solve this problem, the dissolution process and passivation mechanism of chalcopyrite in bioleaching should be first studied, then the rate-limiting steps should be analysed explicitly, and finally the intensifying method can be put forward. Many scholars have made efforts to investigate the dissolution mechanism of chalcopyrite in bioleaching. However, there is no congruence of opinion as yet. Biohydrometallurgy of Chalcopyrite summarizes and discusses the reported research findings. In addition, this book publishes the related results found by the authors' research. Then, the dissolution mechanism of chalcopyrite in bioleaching is interpreted. Finally, the process intensification techniques of chalcopyrite bioleaching are provided and discussed. Hence, this book provides useful reference and guidance in both laboratory research and industrial production.
Nanotechnology in Conservative Dentistry provides a detailed review of the use of nanotechnology in conservative dentistry, from diagnosis and restorative materials, through to tissue engineering and regeneration. This book covers fundamental topics in the field of conservative dentistry, including caries therapy, dentin reconstruction, pulp protection and more; each chapter reviews and discusses how nanotechnology can be implemented as a novel approach to traditional conservative dentistry techniques, exploring the many uses and advantages of this fast-growing technology. Various nanobiomaterials and technologies are covered, as well as assessment of the biocompatibility and toxicological risks of utilizing nanotechnology in dentistry. Nanotechnology in Conservative Dentistry will help dentists and materials science academics alike, understand the potential of nanotechnology in dentistry, building on and going beyond traditional concepts and techniques in this field.
This book provides a timely review of strategies for coping with polluted ecosystems by employing bacteria, fungi and algae. It presents the vast variety of microbial technologies currently applied in the bioremediation of a variety of anthropogenic toxic chemicals, mining and industrial wastes and other pollutants. Topics covered include: microbe-mineral interactions, biosensors in environmental monitoring, iron-mineral transformation, microbial biosurfactants, bioconversion of cotton gin waste to bioethanol, anaerobe bioleaching and sulfide oxidation. Further chapters discuss the effects of pollution on microbial diversity, as well as the role of microbes in the bioremediation of abandoned mining areas, industrial and horticultural wastes, wastewater and sites polluted with hydrocarbons, heavy metals, manganese and uranium.
Introduces an approach to ethical decision making based on treating data as clients Compares the ethics of three professions; engineering, medicine and bioengineering Provides five moral theories to choose from for evaluating ethical decisions, and includes a procedure for applying them to moral analysis, and application of the procedure to example cases. Explains the process of developing a medical product under FDA regulation Explores the role of lawyers in product development, including intellectual property protection Examines a range of ethical cases, from the historical Tuskegee autonomy case to the modern CRISPR-Cas9 patent case.
Bioinspired and Biomimetic Materials for Drug Delivery delves into the potential of bioinspired materials in drug delivery, detailing each material type and its latest developments. In the last decade, biomimetic and bioinspired materials and technology has garnered increased attention in drug delivery research. Various material types including polymer, small molecular, protein, peptide, cholesterol, polysaccharide, nano-crystal and hybrid materials are widely considered in drug delivery research. However, biomimetic and bioinspired materials and technology have shown promising results for use in therapeutics, due to their high biocompatibility and reduced immunogenicity. Such materials include dopamine, extracellular exosome, bile acids, ionic liquids, and red blood cell. This book covers each of these materials in detail, reviewing their potential and usage in drug delivery. As such, this book will be a great source of information for biomaterials scientists, biomedical engineers and those working in pharmaceutical research.
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