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Books > Professional & Technical > Biochemical engineering > Biotechnology > General
Biotechnology has prompted a revolution in science and society in
the truest sense of the word. For what superficially appears to be
a revolution in biotechnology, in effect touches upon the
fundamentals of life and the way in which humans relate to it. This
book will make a significant contribution to the debate surrounding
the effective regulation of biotechnology. The contributing authors
assess how regulatory regimes can accommodate the many different
and often conflicting issues to which biotechnology is giving rise
to (including a very tainted public image). The book's ultimate aim
is to explore ways of designing a regulatory regime that takes heed
of these different demands whilst, at the same time, answering to
the imperatives of effectiveness and efficiency. The book
synthesizes three fields of legal analysis; the first focuses on
the risk-dominated regulation of GM food and bio-agriculture; the
second involves human genetics as a field dominated by
considerations of ethics. Finally, patent law has been chosen as an
area captured by notions of property. With its holistic approach,
The Regulatory Challenge of Biotechnology will be of great interest
to academics, policymakers and regulators as well as biotechnology
and law students.
The advances in microsystems offer new opportunities and
capabilities to develop systems for biomedical applications, such
as diagnostics and therapy. There is a need for a comprehensive
treatment of microsystems and in particular for an understanding of
performance limits associated with the shrinking scale of
microsystems. The new edition of Microsystems for Bioelectronics
addresses those needs and represents a major revision, expansion
and advancement of the previous edition. This book considers
physical principles and trends in extremely scaled autonomous
microsystems such as integrated intelligent sensor systems, with a
focus on energy minimization. It explores the implications of
energy minimization on device and system architecture. It further
details behavior of electronic components and its implications on
system-level scaling and performance limits. In particular,
fundamental scaling limits for energy sourcing, sensing, memory,
computation and communication subsystems are developed and new
applications such as optical, magnetic and mechanical sensors are
presented. The new edition of this well-proven book with its unique
focus and interdisciplinary approach shows the complexities of the
next generation of nanoelectronic microsystems in a simple and
illuminating view, and is aimed for a broad audience within the
engineering and biomedical community.
This volume discusses the role of ZIF-8 composites in water
decontamination as an adsorbent and photocatalyst. Metal-organic
frameworks (MOFs) are advanced porous materials and are promising
adsorbents with facile modifications, high specific surface area,
controllable porosity, and tailored surface properties. Water
pollution is a major concern and has endangered human health.
Recently, researchers have designed MOFs for use in remediation.
Tissue engineering involves seeding of cells on bio-mimicked
scaffolds providing adhesive surfaces. Researchers though face a
range of problems in generating tissue which can be circumvented by
employing nanotechnology. It provides substrates for cell adhesion
and proliferation and agents for cell growth and can be used to
create nanostructures and nanoparticles to aid the engineering of
different types of tissue. Written by renowned scientists from
academia and industry, this book covers the recent developments,
trends and innovations in the application of nanotechnologies in
tissue engineering and regenerative medicine. It provides
information on methodologies for designing and using biomaterials
to regenerate tissue, on novel nano-textured surface features of
materials (nano-structured polymers and metals e.g.) as well as on
theranostics, immunology and nano-toxicology aspects. In the book
also explained are fabrication techniques for production of
scaffolds to a series of tissue-specific applications of scaffolds
in tissue engineering for specific biomaterials and several types
of tissue (such as skin bone, cartilage, vascular, cardiac, bladder
and brain tissue). Furthermore, developments in nano drug delivery,
gene therapy and cancer nanotechonology are described. The book
helps readers to gain a working knowledge about the nanotechnology
aspects of tissue engineering and will be of great use to those
involved in building specific tissue substitutes in reaching their
objective in a more efficient way. It is aimed for R&D and
academic scientists, lab engineers, lecturers and PhD students
engaged in the fields of tissue engineering or more generally
regenerative medicine, nanomedicine, medical devices,
nanofabrication, biofabrication, nano- and biomaterials and
biomedical engineering.
Chitosan in Biomedical Applications provides a thorough insight
into the complete chitosan chemistry, collection, chemical
modifications, characterization and applications of chitosan in
biomedical applications and healthcare fields. Chitosan, a
biopolymer of natural origin, has been explored for its variety of
applications in biomedical research, medical diagnostic aids and
material science. It is the second most abundant natural biopolymer
after cellulose, and considered as an excellent excipient because
of its non-toxic, stable, biodegradable properties. Several
research innovations have been made on applications of chitosan in
biomedical applications. The book explores key topics, such as
molecular weight, degree of deacetylation, and molecular geometry,
along with an emphasis on recent advances in the field written by
academic, industry, and clinical researchers. Chitosan in
Biomedical Applications will be of interest to those in biomedical
fields including the biomaterials and tissue engineering community
investigating and developing biomaterials for biomedical
applications, particularly graduate students, young faculty and
others exploring chitosan-based materials.
This document is exclusively dedicated to DNA. It explains the
secrets of DNA from all corners. Presented in a simple, lucid
manner; it will useful to all involved in bioscience. In all it
consists 12 chapters, figures, photos and a wholesome glossary of
the terms related to DNA.
This volume discusses the role of MOFs in removal of pharmaceutical
pollutants. Metal-organic frameworks (MOFs) are advanced porous
materials and are promising adsorbents with facile modifications,
high specific surface area, controllable porosity, and tailored
surface properties. Pharmaceutical pollution is an issue of concern
due to its effects on environment. Recently, researchers have
designed MOFs for use in remediation.
Nanoparticle therapeutics: Production Technologies, Types of
Nanoparticles, and Regulatory Aspects employs unique principles for
applications in cell-based therapeutics, diagnostics and
mechanistics for the study of organ physiology, disease etiology
and drug screening of advanced nanoparticles and nanomaterials. The
book focuses on the extrapolation of bioengineering tools in the
domain of nanotechnology and nanoparticles therapeutics,
fabrication, characterization and drug delivery aspects. It
acquaints scientists and researchers on the experiential and
experimental aspects of nanoparticles and nanotechnology to equip
their rational application in various fields, especially in
differential diagnoses and in the treatment of diverse diseased
states. This complete resource provides a holistic understanding of
the principle behind formation, characterization, applications,
regulations and toxicity of nanoparticles employing myriad
principles of nanotechnology. Investigators, pharmaceutical
researchers, and advanced students working on technology
advancement in the areas of designing targeted therapies, nanoscale
imaging systems and diagnostic modalities in human diseases where
nanoparticles can be used as a critical tool for technology
advancement in drug delivery systems will find this book useful.
Microbial Biotechnology is wide-ranging, multi-disciplinary
activities which include recombinant DNA techniques, cloning and
the application of microbes to the production of goods from bread
to antibiotics. This book is an attempt to highlight the
significant aspects of the vast subject area of microbial
biotechnology likes bioinformatics tool for PCR primer designing,
fungal biotransformations, bioremediation by microbes, natural
products from fungi, microbial diversity etc to provide a complete
overview of the subject. It also addresses the role of bacterial
plasmid in xenobiotic degradation, antimicrobial resistance in
bacteria, ultraviolet-B radiation effect on microbes and human
health. The book will be valuable to the researchers, biologist,
microbiologist, scientists, post graduate students of microbiology,
agriculture, biotechnology and medical science also.
Chitosan in Drug Delivery provides thorough insights into chitosan
chemistry, collection, chemical modifications, characterization and
applications in the pharmaceutical industry and healthcare fields.
The book explores molecular weight, degree of deacetylation and
molecular geometry, emphasizing recent advances in the field as
written by academic, industry and regulatory scientists. It will be
a useful resource for pharmaceutical scientists, including
industrial pharmacists, analytical scientists, postgraduate
students, health care professionals and regulatory scientists
actively involved in pharmaceutical product and process development
in natural polymers containing drug delivery.
"Biotechnology and Biology of Trichoderma" serves as a
comprehensive reference on the chemistry and biochemistry of one of
the most important microbial agents, Trichoderma, and its use in an
increased number of industrial bioprocesses for the synthesis of
many biochemicals such as pharmaceuticals and biofuels. This book
provides individuals working in the field of Trichoderma,
especially biochemical engineers, biochemists and biotechnologists,
important information on how these valuable fungi can contribute to
the production of a wide range of products of commercial and
ecological interest.
Provides a detailed and comprehensive coverage of the chemistry,
biochemistry and biotechnology of Trichoderma, fungi present in
soil and plantsIncludes most important current and potential
applications of Trichoderma in bioengineering, bioprocess
technology including bioenergy & biofuels, biopharmaceuticals,
secondary metabolites and protein engineeringIncludes the most
recent research advancements made on Trichoderma applications in
plant biotechnology and ecologyand environment"
Herbal Biomolecules in Healthcare Applications presents extensive
detailed information on all the vital principles, basics and
fundamental aspects of multiple herbal biomolecules in the
healthcare industry. This book examines important herbal
biomolecules including alkaloids, glycosides, flavonoids,
anthraquinones, steroids, polysaccharides, tannins and polyphenolic
compounds, terpenes, fats and waxes, proteins and peptides, and
vitamins. These herbal biomacromolecules are responsible for
different bioactivities as well as pharmacological potentials. A
systematic understanding of the extraction, purification,
characterization, applications of these herbal biomolecules and
their derivatives in healthcare fields is developed in this
comprehensive book. Chapters explore the key topics along with an
emphasis on recent research and developments in healthcare fields
by leading experts. They include updated literature review of the
relevant key topics, good quality illustrations, chemical
structures, flow charts, well-organized tables and case studies.
Herbal Biomolecules in Healthcare Applications will be useful for
researchers working on natural products and biomolecules with
bioactivity and nutraceutical properties. Professionals
specializing in scientific areas such as biochemistry,
pharmacology, analytical chemistry, organic chemistry, clinics, or
engineering focused on bioactive natural products will find this
book useful.
Polymers are important and attractive biomaterials for
researchers and clinical applications due to the ease of tailoring
their chemical, physical and biological properties for target
devices. Due to this versatility they are rapidly replacing other
classes of biomaterials such as ceramics or metals. As a result,
the demand for biomedical polymers has grown exponentially and
supports a diverse and highly monetized research community.
Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical
polymers are expected to achieve a CAGR of 9.8% until 2015,
supporting a current research community of approximately
28,000+.
Summarizing the main advances in biopolymer development of the
last decades, this work systematically covers both the physical
science and biomedical engineering of the multidisciplinary field.
Coverage extends across synthesis, characterization, design
consideration and biomedical applications. The work supports
scientists researching the formulation of novel polymers with
desirable physical, chemical, biological, biomechanical and
degradation properties for specific targeted biomedical
applications.
Combines chemistry, biology and engineering for expert and
appropriate integration of design and engineering of polymeric
biomaterials Physical, chemical, biological, biomechanical and
degradation properties alongside currently deployed clinical
applications of specific biomaterials aids use as single source
reference on field. 15+ case studies provides in-depth analysis of
currently used polymeric biomaterials, aiding design considerations
for the future
Simulating for a crisis is far more than creating a simulation of a
crisis situation. In order for a simulation to be useful during a
crisis, it should be created within the space of a few days to
allow decision makers to use it as quickly as possible.
Furthermore, during a crisis the aim is not to optimize just one
factor, but to balance various, interdependent aspects of life. In
the COVID-19 crisis, decisions had to be made concerning e.g.
whether to close schools and restaurants, and the (economic)
consequences of a 3 or 4-week lock-down had to be considered. As
such, rather than one simulation focusing on a very limited aspect,
a framework allowing the simulation of several different scenarios
focusing on different aspects of the crisis was required. Moreover,
the results of the simulations needed to be easily understandable
and explainable: if a simulation indicates that closing schools has
no effect, this can only be used if the decision makers can explain
why this is the case. This book describes how a simulation
framework was created for the COVID-19 crisis, and demonstrates how
it was used to simulate a wide range of scenarios that were
relevant for decision makers at the time. It also discusses the
usefulness of the approach, and explains the decisions that had to
be made along the way as well as the trade-offs. Lastly, the book
examines the lessons learned and the directions for the further
development of social simulation frameworks to make them better
suited to crisis situations, and to foster a more resilient
society.
Microorganisms are ubiquitous and indispensable for the existence
of mankind. They show diversity in size, shape, metabolism and the
range of positive functions they perform for sustaining the life on
this planet. Bacteria have been exploited by the mankind since
times immemorial for the production of various foods and enzymes.
They reveal several types of metabolic reactions which are absent
in eukaryotic organisms. The present book highlights the potential
of microorganisms in solving the global energy crisis. Presently,
the world is facing energy crisis due to depleting fossil fuels
which are expected to get exhausted during the next 50 yeaOne of
the alternative energy resources for the new millennium is expected
to be the renewable energy including biomass from which a variety
of biofuels can be obtained by the exploitation of microbes. This
volume has been organized in 13 s which have been prepared to
provide the readers with both an in-depth study and a broad
perspective of microorganisms for sustainability of mankind.
Further, it makes the readers familiar with the diversity in energy
generating pathways among different groups of microorganisms and
different types of biomass energy resources available on this
planet and the various possibilities which can be exploited for
converting these in to alternate energy sources with the help of
microbes. A great effort has been made to provide the readers a
comprehensive knowledge about different alternative fuels and value
added products from microbes for the 21st century. It is hoped that
this volume will prove useful to the students and professionals who
are pursuing their career in Microbiology, Biotechnology,
Biochemistry, Environmental sciences and Energy studies related to
the alternate biofuels to solve the global energy crisis.
Despite the recent advances made in the improvement of crucifer
crops using conventional breeding techniques, the yield levels and
the oil and meal quality could not be improved as expected. The
understanding of genetic material (DNA/RNA) and its manipulation by
scientists has provided the opportunity to improve crucifers by
increasing its diversity beyond conventional genetic limitations.
The application of the biotechnological techniques will have major
impacts in two ways: first, it provides a number of
techniques/methods for efficient selection for favorable variants
and second, it gives an opportunity to utilize alien variation
available in the crucifers by using the novel techniques of
biotechnology to develop high yielding varieties with good
nutritional quality, having resistance to insect, pest, and disease
resistance.
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