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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
Ditch processed foods and feed yourself and your family the cleanest, healthiest food on the planet by stocking your kitchen, shopping and cooking with Food Babe Kitchen. Over 100 mouthwatering recipes from Healing Turmeric Hummus and Glowing Green Juice to Sweet Potato Waffles with Cinnamon Whipped Butter and Almond Butter Freezer Fudge will show readers how delicious and simple it is to eat healthy, real food. Easy-to-follow directions, eye-catching photography and simple substitutions to accommodate vegan, dairy-free, grain-free and other diets, make this the ultimate guide to getting back into the kitchen to create healthful meals for yourself and those you love. Say good-bye to the Standard American Diet and set your own standards for your health! Now in paperback.
Presents classic and recent findings on immunological dysfunctions caused by food allergies-coordinating the most advanced clinical techniques and assessment methods with practical insights for treatment and patient care.
This is a review text on medical microbiology and immunology containing approximately 625 board-type review questions on left-hand pages with answers and explanations on facing right-hand pages. It is designed for medical students taking microbiology as well as for those studying for Step 1 of the National Board Exams and is also useful for Step 3 National Boards on infectious diseases or allergy and immunology. The book's main sections cover general and medical microbiology, bacteriology, virology, immunology, and parasitology. The answers summarize relevant information and point out the fault in incorrect answers. Line drawings and figures are used for questions concerning structure of both molecules and organisms and for interpreting graphical results. Authors Reese, Brownell, and Nair, all with the Medical College of Georgia, bring a combined total of some 85 years of medical school teaching experience to their development of the questions and annotated answers for this book.
This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked to the suppression of T-cell receptor signaling and co-stimulatory molecules. Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation". Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for the therapy of autoimmune diseases. Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike.
This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease -describes the molecular architecture of the complement system -details the structure of complement genes -discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins -analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway -elucidates the regulation of complement gene expression and the structure and function of bioactive peptides -explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria -and more!
Recognizing the explosive growth in information on intravenous immunoglobulins (IVIGs), this exhaustive single-source volume surveys all available literature on the employment of IVIG preparations in clinical practice from pharmacoeconomics and pharmacokinetics to prophylaxis and management of infectious and autoimmune diseases.
Posing the urgent questions that anyone with food allergies will think to ask-and then some- Food Allergies provides practical, sensitive, and scientific guidance on the topics that affect your life. Allergy expert Scott H. Sicherer addresses the full spectrum of food allergies, from mild to life threatening and from single foods to food families, clearing up misconceptions along the way. He explores how exposure to foods can bring about an allergic response, describes the symptoms of food allergy, and illuminates how food allergies develop. Organized in an accessible Q&A format and illustrated with case studies, the book thoroughly explains how to prevent exposure to a known allergen at home, at school, in restaurants, and elsewhere. Dr. Sicherer also gives valuable advice about what to do if exposure occurs, including how to handle an anaphylactic emergency. Finally, he describes tests for diagnosing food allergies and chronic health problems caused by food allergies, such as eczema, hives, and respiratory and gastrointestinal symptoms. In this thoroughly updated new edition, Dr. Sicherer* describes new approaches to prevent food allergies* presents cutting-edge theories on risk factors for developing food allergies* describes innovative allergy tests to improve diagnosis* explains how to administer emergency medications for severe reactions* focuses on new allergens of concern, such as pink peppercorns* analyzes studies suggesting that resolution of an allergy might be predictable* talks about the role of "healthy diet"* lists additional resources, including allergy-related apps* provides revised school food allergy guidelines* offers insights into food allergy bullying-and advice to reduce it Dr. Sicherer also reviews food reactions that are not allergic (such as lactose intolerance and celiac disease), advises how to get adequate nutrition when you must avoid dietary staples, and discusses whether allergies ever go away (they do-and sometimes they return).
This book draws together important facts, in particular areas of vascular biology, and allows the generation of hypotheses and principles that unite an area and define newer horizons. It is designed for scientists and physicians interested in immunology, inflammation and cardiovascular diseases.
Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.
This volume provides a thorough overview of current knowledge of stress proteins in both normal and disease physiology. It draws upon current stress protein research to evaluate the potential for developing new diagnostic, prophylactic and therapeutic approaches to control human disease.
NEW YORK TIMES BESTSELLER Tabitha Brown, the #1 New York Times bestselling author of Feeding the Soul, presents her first cookbook-full of easy, family-friendly vegan recipes and stories from the spirit, inspired by her health journey and love of delicious food. Sometimes people say to Tabitha Brown, "I've never eaten vegan before." As Tab says, "Have you ever eaten an apple?" After living with a terrible undiagnosed illness for more than a year and a half, Tab was willing to try anything to stop the pain. Inspired by the documentary What the Health, she tried a thirty-day vegan challenge-and never looked back. Wanting to inspire others to make changes that might improve their own lives, she started sharing her favorite plant-based recipes in her signature warm voice with thousands, and now millions, of online fans. Tab's recipes are flexible, creative, and filled with encouragement, so you trust yourself to cook food the way it makes you happy. If you're already a "cooking from the spirit" sort of person, you'll love how much freedom Tab gives to make these delicious vegan dishes your own. If you're newer to cooking-or to vegan cooking-Tab will help you get comfortable in the kitchen and, most important, have fun doing it! In this joyful book, Tab shares personal stories, inspirational "Tabisms," and more than eighty easy, family-friendly recipes, including: Yam Halves Topped with Maple-Cinnamon Pecan Glaze Stuffed Avocado Jackfruit Pot Roast Crab-less Cakes with Spicy Tartar Sauce Who Made the Potato Salad? Kale and Raspberry Salad Strawberry Cheesecake Cups Cooking from the Spirit is for anyone interested in plant-based eating and all lovers of food, plus anyone who wants a little warm inspiration in their lives. As Tab says, "Honey, now let's go on and get to cooking from the spirit. Yes? Very good!"
This volume covers advances in the field of respiratory diseases, reflecting the recent and dramatic expansion of knowledge regarding the determinants of respiratory health, screening tests for early pulmonary lesions, therapeutic interventions for respiratory infections and strategies for prevention. It examines indoor and outdoor environmental sources of respiratory diseases, including levels of pollutants, air conditioning, indoor air quality and airborne allergens. Exploring ways to promote the respiratory health of both the individual and the community, Prevention of Respiratory Diseases covers areas including: the role of most of the known extrinsic and potentially preventable determinants in respiratory diseases; developments in epidemiology and children's respiratory health; the relationship between respiratory diseases and occupations; individual sensitivity or susceptibility to the effects of air pollutants; genetic, epidemiological and immunological markers, markers for bronchial cancer and the protease-antiprotease system; and the connection between tobacco smoke and respiratory diseases.;This resource is intended for pulmonologists, clinical immunologists and allergists, oncologists, physiologists, infectious disease specialists, respiratory therapists and graduate and medical school students in these disciplines.
Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.
This volume presents chapters by leading figures researching the
various pathways by which stress may interfere with health
maintenance and contribute to disease etiology and progression.
Their work focuses on direct effects of stress on the immune and
endocrine systems, on behavioral factors in diseases such as cancer
and diabetes, and with the general role of stress in illness
processes.
Biological immunity as we know it does not exist until the late nineteenth century. Nor does the premise that organisms defend themselves at the cellular or molecular levels. For nearly two thousand years "immunity," a legal concept invented in ancient Rome, serves almost exclusively political and juridical ends. "Self-defense" also originates in a juridico-political context; it emerges in the mid-seventeenth century, during the English Civil War, when Thomas Hobbes defines it as the first "natural right." In the 1880s and 1890s, biomedicine fuses these two political precepts into one, creating a new vital function, "immunity-as-defense." In "A Body Worth Defending," Ed Cohen reveals the unacknowledged political, economic, and philosophical assumptions about the human body that biomedicine incorporates when it recruits immunity to safeguard the vulnerable living organism. Inspired by Michel Foucault's writings about biopolitics and biopower, Cohen traces the migration of immunity from politics and law into the domains of medicine and science. Offering a genealogy of the concept, he illuminates a complex of thinking about modern bodies that percolates through European political, legal, philosophical, economic, governmental, scientific, and medical discourses from the mid-seventeenth century through the twentieth. He shows that by the late nineteenth century, "the body" literally incarnates modern notions of personhood. In this lively cultural rumination, Cohen argues that by embracing the idea of immunity-as-defense so exclusively, biomedicine naturalizes the individual as the privileged focus for identifying and treating illness, thereby devaluing or obscuring approaches to healing situated within communities or collectives.
Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma (~10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 3rd leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress towards achieving significant improvements in HCC and CCA clinical management and patient survival outcomes. Towards this goal, this special edition of Advances in Cancer Research is focused on providing a comprehensive, timely and authoritative reviews covering such topics of significant scientific and clinical relevance, including hepatobiliary cancer risk mechanisms and risk-predictive molecular biomarkers; causes and functional intricacies of inter- and intratumor heterogeneity; novel insights into the role of tumor microenvironment and key signaling pathways in promoting hepatobiliary cancer progression, therapeutic resistance and immunosuppression; emerging biomarkers of HCC and CCA prognosis; advances in molecular genomics for personalizing tumor classification and targeted therapies; innovative preclinical cell culture modeling for hepatobiliary cancer drug discovery; and current and emerging trends in hepatobiliary cancer molecular therapeutic targeting and immunotherapies.
This book describes, in detail, tested techniques for the produc-tion and use of monoclonal antibodies. It covers those aspects of interest to all scientists working with monoclonal antibodies and presents methods in a step-by-step format for easy refer-ence. The text serves as a laboratory manual; and discusses rationale behind each method, and the choices between methods. It also provides a rational basis where several alternative methods are available.
To some, food allergies seem like fabricated cries for attention. To others, they pose a dangerous health threat. Food allergies are bound up with so many personal and ideological concerns that it is difficult to determine what is medical and what is myth. Another Person's Poison parses the political, economic, cultural, and genuine health factors of a phenomenon that dominates our interactions with others and our understanding of ourselves. For most of the twentieth century, food allergies were considered a fad or junk science. While many physicians and clinicians argued that certain foods could cause a range of chronic problems, from asthma and eczema to migraines and hyperactivity, others believed that allergies were psychosomatic. 'This book traces the trajectory of this debate and its effect on public-health policy and the production, manufacture, and consumption of food. Are rising allergy rates purely the result of effective lobbying and a booming industry built on self-diagnosis and expensive remedies? Or should physicians become more flexible in their approach to food allergies and more careful in their diagnoses? Exploring the issue from scientific, political, economic, social, and patient-centered perspectives, this book is the first to engage fully with the history of a major modern affliction, illuminating society's troubled relationship with food, disease, nature, and the creation of medical knowledge.
A breathtaking one in five people in the U.S. has a health condition related to food-from disruptive sensitivities and intolerances to serious allergic reactions that can send them to the ER. These food-related problems are on a historic rise across all ages. And the spectrum of these ailments is wide and deep, with many tricky "masqueraders" in the mix to create a lot of confusion, potential misdiagnoses, and faulty or poor treatment-and immeasurable suffering for millions of people. The good news: Dr. Ruchi Gupta, on the front lines of this silent epidemic, now shares revolutionary research from her lab and clinical practice. In Food Without Fear, Dr. Gupta illuminates this misunderstood spectrum and offers a new approach to managing adverse reactions to food with a practical plan to end the misery and enjoy eating with ease. This panoramic view empowers you to know what questions to ask your doctor to get the correct diagnosis. From debunking common myths (an allergy and an intolerance aren't the same thing-but both can have life-threatening consequences) to identifying masqueraders, to understanding triggers (including environmental factors), as well as the microbiome's role in adverse food reactions, these pages hold the answers. Using a framework of Identify and Empower, Treat, Manage and Prevent, and Thrive, Food Without Fear offers hope, help-and food freedom-to the millions of people who so need it. Developed by world-renowned researcher Dr. Ruchi Gupta, this revolutionary spectrum approach empowers and informs so you can take charge of your health. In Food Without Fear, you'll learn: - The differences between an allergy and an intolerance or sensitivity - What "masqueraders" are and how to identify them - Which health conditions are mistaken for food allergies-or can be triggered by them - The top offenders that can spark an allergy attack or intolerance - The surprising allergies on the rise (think red meat and exercise) - The potential connections between genetics, environmental exposures, and risk for developing food-related conditions - How to S.T.O.P. the misery and chart your healthy path forward Offering assessments, information on the most up-to-date treatments, and practical tips for keeping yourself safe, Food Without Fear welcomes you back to the table.
Advances in Cancer Research, Volume 148, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.
A broad and experienced team, including medical oncologists and life scientists, have collaborated to produce this practical guide to cancer immunotherapy. It provides a compendium of best practice, including 23 case studies to act as models for professionals to make decisions, either for individual patients or as the basis for using immunotherapy across an organisation, planning area, region or country. As well as introducing all key concepts, expert practitioners provide a guide to future treatments using novel technologies, discuss key problems and suggest solutions, and consider the costs of immunotherapy treatments.This guide also makes an excellent training tool, which will help new teams and clinical staff to develop procedures, and adopt best practice. This resource is produced in partnership with the Association of Cancer Physicians (ACP).
Epigenetic Regulation of Cancer in Response to Chemotherapy, Volume 158 of the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Since the identification of the first cases of the coronavirus in December 2019, there has been a significant amount of confusion regarding the origin and spread of the so-called 'coronavirus', SARS-CoV-2, and the cause of the disease COVID-19. Conflicting messages from the media and officials across different countries and organizations, the abundance of disparate sources of information, unfounded conspiracy theories on the origins of the virus, unproven therapies, and inconsistent public health measures, have all served to increase anxiety in the population. Where did the virus come from? How is it transmitted? How does it cause disease? Is it like flu? What is a pandemic? In this concise and accessible introduction, a leading expert provides answers to these commonly asked questions. This revised and updated edition now also covers how the virus mutates, how important these mutations are, how vaccines work, and what we can expect in the near and long-term future. |
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