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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology

Medicinal Plants in the Asia Pacific for Zoonotic Pandemics - Family Amborellaceae to Vitaceae (Paperback): Christophe Wiart Medicinal Plants in the Asia Pacific for Zoonotic Pandemics - Family Amborellaceae to Vitaceae (Paperback)
Christophe Wiart
R3,193 Discovery Miles 31 930 Ships in 12 - 17 working days

Medicinal Plants in the Asia Pacific for Zoonotic Pandemics provides an unprecedented, comprehensive overview of the phylogeny, botany, ethnopharmacology, and pharmacology of more than 100 plants used in the traditional medical systems of Asia and Pacific. It discusses their actions and potentials against viruses, bacteria, and fungi that represent a threat of epidemic and pandemic diseases, with an emphasis on the molecular basis and cellular pathways. This book presents scientific names, the botanical classification, traditional medicinal uses, active chemical constituents, and pharmacology. This volume is a critical reference for anyone involved in the discovery of lead molecules or phytopharmaceutical products for the prevention or treatment of pandemic viral, bacterial, or fungal infections. FEATURES Phylogenetic presentation of medicinal plants and a chemotaxonomical rationale of antiviral, antibacterial, and antifungal actions Discusses the chemical structure-activity relationship, pharmacokinetics, and oral bioavailability of antimicrobial principles Introduces the molecular mechanism of natural products on viruses, bacteria, and fungi Contains a selection of botanical plates and useful bibliographic references This book is a useful research tool for postgraduates, academics, and the pharmaceutical, herbal, and nutrition industries. Medicinal Plants in the Asia Pacific for Zoonotic Pandemics includes commentary sections that invite further research and reflection on the fascinating and timely subject of the development of drugs and herbals from Asia-Pacific medicinal plants to safeguard humanity and other life forms against the forthcoming waves of viral, bacterial, or fungal pandemics. This book is an ideal reference text for medicinal plant enthusiasts.

Clinical Immunology & Serology - A Laboratory Perspective (Paperback, 5th Revised edition): Linda E Miller, Christine... Clinical Immunology & Serology - A Laboratory Perspective (Paperback, 5th Revised edition)
Linda E Miller, Christine Dorresteyn Stevens
R2,829 R2,622 Discovery Miles 26 220 Save R207 (7%) Ships in 12 - 17 working days

The perfect balance of theory and practice! Here's the practical introduction you need to understand the essential theoretical principles of clinical immunology and the serological and molecular techniques commonly used in the laboratory. You'll begin with an introduction to the immune system; then explore basic immunologic procedures; examine immune disorders; and study the serological and molecular diagnosis of infectious disease. An easy-to-read, student-friendly approach emphasizes the direct application of theory to clinical laboratory practice. Each chapter is a complete learning module with learning outcomes, chapter outlines, theoretical principles, illustrations, and definitions of relevant terminology. Review questions and case studies help you assess your mastery of the material. A glossary at the end of the book puts must-know information at your fingertips. An access code inside new printed texts unlocks Lab Exercises and Branching Case Studies online at FADavis.com that offer more opportunities to apply theory to clinical laboratory practice.

Systems Immunology - An Introduction to Modeling Methods for Scientists (Paperback): Jayajit Das, Ciriyam Jayaprakash Systems Immunology - An Introduction to Modeling Methods for Scientists (Paperback)
Jayajit Das, Ciriyam Jayaprakash
R1,489 Discovery Miles 14 890 Ships in 12 - 17 working days

"Taken together, the body of information contained in this book provides readers with a bird's-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." -Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.

Food Allergy - Molecular and Clinical Practice (Paperback): Andreas L Lopata Food Allergy - Molecular and Clinical Practice (Paperback)
Andreas L Lopata
R1,437 Discovery Miles 14 370 Ships in 12 - 17 working days

Food allergy is an adverse immunological reaction to allergens present in food. Up to 4% adults and 8% children are affected by food allergy. The increase in allergic diseases to food has led to the need for better diagnostics and more effective therapeutic approaches. This book describes the molecular biology and immunology of major food allergens, from laboratory based science to clinical immunology, encompassing novel characterisation and quantification methods, the application of recombinant food allergens in molecular diagnosis and the development of novel therapeutics. This book is the ideal reference tool for researchers, students and allergy clinicians to accurately diagnose and manage food allergies.

Nanomedicine for Inflammatory Diseases (Paperback): Lara Scheherazade Milane, Mansoor M. Amiji Nanomedicine for Inflammatory Diseases (Paperback)
Lara Scheherazade Milane, Mansoor M. Amiji
R1,434 Discovery Miles 14 340 Ships in 12 - 17 working days

Nanomedicine for Inflammatory Diseases is a cutting-edge resource for clinicians and scientists alike, working at the intersection of development and clinical therapeutics. This text is ideal for graduate level courses in nanomedicine, translational medicine, or inflammatory disease. This book is a progressive hallmark in translational medicine as it unites clinicians treating inflammatory disease with scientists developing experimental nanomedicine therapeutics. The commonality is made through a translational nanomedicine expert - bridging the gap between the laboratory benchtop and the clinical bedside.

Health and the Gut - The Emerging Role of Intestinal Microbiota in Disease and Therapeutics (Paperback): William Olds Health and the Gut - The Emerging Role of Intestinal Microbiota in Disease and Therapeutics (Paperback)
William Olds
R2,553 Discovery Miles 25 530 Ships in 12 - 17 working days

This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut-the gut microbiome-is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: * Gut microbiome's roles in the pathogenesis of obesity and autoimmune disease * The effect of nutrition on the richness of the microbial community * The stability of the microbiome to various stressors * Emerging ways to diagnose diseases using the microbiome * Exciting prospects for using these microbes to cure disease This easily accessible reference volume offers a comprehensive guide to this relatively new field of study. Edited by a researcher from Yale University, Health and the Gut: The Emerging Role of Intestinal Microbiota in Disease and Therapeutics is an authoritative and easy-to-use reference, ideal for both researchers in the field and those who wish to gain more information about the impact of gut microbiota on human health.

Comparative Immunoglobulin Genetics (Paperback): Azad K. Kaushik, Yfke Pasman Comparative Immunoglobulin Genetics (Paperback)
Azad K. Kaushik, Yfke Pasman
R2,532 Discovery Miles 25 320 Ships in 12 - 17 working days

This contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine-other species than the traditional subjects of mice and humans-are relevant to antibody design and engineering. These new perspectives find direct application in the cutting-edge areas of antibody design, engineering and therapeutics, antibody-drug conjugates, and novel antibody-based vaccines. This book fills the need to provide updated knowledge of this newly exploded area that is finding applications in new drug development. No other competing books on the topic are available in the market. The book will be of great interest to immunologists, immunology researchers, immunogeneticists, researchers in pharmaceutical science, those involved in the infectious disease and antibody therapeutics areas, and many others.

Vaccination Programmes - Epidemiology, Monitoring, Evaluation (Paperback): Susan Hahne, Kaatje Bollaerts, Paddy Farrington Vaccination Programmes - Epidemiology, Monitoring, Evaluation (Paperback)
Susan Hahne, Kaatje Bollaerts, Paddy Farrington
R1,255 Discovery Miles 12 550 Ships in 9 - 15 working days

Vaccination programmes are of vital importance to public health and are present in virtually every country in the world. By promoting an understanding of the diverse effects of vaccination programmes, this textbook discusses how epidemiologic methods can be used to study, in real life, their impacts, benefits and risks. Written by expert practitioners in an accessible and concise style, this book is interspersed with practical examples which allow readers to acquire understanding through real-life data and problems. Part I provides an overview of basic concepts in vaccinology, immunology, vaccination programmes, infectious disease transmission dynamics, the various impacts of vaccination programmes and their societal context. Part II covers the main field tools used for the epidemiological evaluation of vaccination programmes: monitoring coverage and attitudes towards vaccination, surveillance of vaccine-preventable diseases and pathogens, seroepidemiological studies, methods to assess impact and outbreak investigation. Part III is dedicated to vaccine effectiveness and its assessment. Part IV includes an overview of the potential risks of vaccination and how to study these. Lastly, Part V deals with methods for an integrated assessment of benefits and risks of vaccination programmes. Suitable for professionals working in public health, epidemiology, biology and those working in health economics and vaccine development, Vaccination Programmes also serves as a textbook for postgraduate students in public health, epidemiology and infectious diseases. The book is aimed at all those involved in the many aspects of vaccination programmes, including public health professionals and epidemiologists. Its primary target audiences are master and doctoral students in infectious disease epidemiology and public health, post-doctoral participants of field epidemiology training programmes and public health professionals working in the post-implementation epidemiological evaluation of vaccines and vaccination programmes.

Synthetic Peptide Vaccine Models - Design, Synthesis, Purification, and Characterization (Hardcover): Mesut Karahan Synthetic Peptide Vaccine Models - Design, Synthesis, Purification, and Characterization (Hardcover)
Mesut Karahan
R3,485 Discovery Miles 34 850 Ships in 12 - 17 working days

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes - the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Bayesian Analysis of Infectious Diseases - COVID-19 and Beyond (Hardcover): Lyle D. Broemeling Bayesian Analysis of Infectious Diseases - COVID-19 and Beyond (Hardcover)
Lyle D. Broemeling
R3,095 Discovery Miles 30 950 Ships in 10 - 15 working days

Bayesian Analysis of Infectious Diseases -COVID-19 and Beyond shows how the Bayesian approach can be used to analyze the evolutionary behavior of infectious diseases, including the coronavirus pandemic. The book describes the foundation of Bayesian statistics while explicating the biology and evolutionary behavior of infectious diseases, including viral and bacterial manifestations of the contagion. The book discusses the application of Markov Chains to contagious diseases, previews data analysis models, the epidemic threshold theorem, and basic properties of the infection process. Also described are the chain binomial model for the evolution of epidemics. Features: Represents the first book on infectious disease from a Bayesian perspective. Employs WinBUGS and R to generate observations that follow the course of contagious maladies. Includes discussion of the coronavirus pandemic as well as many examples from the past, including the flu epidemic of 1918-1919. Compares standard non-Bayesian and Bayesian inferences. Offers the R and WinBUGS code on at www.routledge.com/9780367633868

Handbook of Therapeutic Biomarkers in Cancer (Hardcover, 2nd edition): Sherry X. Yang, Janet E. Dancey Handbook of Therapeutic Biomarkers in Cancer (Hardcover, 2nd edition)
Sherry X. Yang, Janet E. Dancey
R6,947 Discovery Miles 69 470 Ships in 12 - 17 working days

This book provides a comprehensive overview of the fast-evolving subject of clinical application of cancer therapeutic biomarkers. The second edition captures significant progress of cancer immunotherapy and emphasizes the genetic basis for selective cancer treatment. It covers an in-depth insight on biomarkers across a broad area of cancer research and oncology with a wealth of integrated genetic and molecular information about specific therapies by a multidisciplinary team of internationally recognized experts. Each chapter focuses on a class of targeted, immunologic, or chemotherapy agents and their companion biomarkers that predict response, benefit or resistance, and severe adverse event. The book will serve as a handbook for health professionals and scientists on the current applicable biomarkers in the management of cancer. The vision into the systemic classification and statistical consideration of therapeutic biomarkers summarized by the book editors and chapter authors will help advance precision medicine-a precisely tailored cancer treatment strategy for cancer patient care.

AI for Immunology (Paperback): Louis J. Catania AI for Immunology (Paperback)
Louis J. Catania
R748 Discovery Miles 7 480 Ships in 12 - 17 working days

The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures. Key features: A highly accessible and wide-ranging short introduction to AI for immunology Includes a chapter on COVID-19 and pandemics Includes scientific and clinical considerations, as well as immune and autoimmune diseases

AI for Immunology (Hardcover): Louis J. Catania AI for Immunology (Hardcover)
Louis J. Catania
R1,767 Discovery Miles 17 670 Ships in 12 - 17 working days

The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures. Key features: A highly accessible and wide-ranging short introduction to AI for immunology Includes a chapter on COVID-19 and pandemics Includes scientific and clinical considerations, as well as immune and autoimmune diseases

The Long Covid Handbook (Paperback): Gez Medinger, Danny Altmann The Long Covid Handbook (Paperback)
Gez Medinger, Danny Altmann
R350 R280 Discovery Miles 2 800 Save R70 (20%) Ships in 5 - 10 working days

Understand, manage, and treat Long Covid. Reports suggest that over 100m people around the world are living with Long Covid (more than 1.5m in the UK) yet reliable, clear information and guidance remains scarce. This book is the definitive guide to understanding, managing and treating the condition. Written by the world's leading immunologist Professor Danny Altmann and expert patient Gez Medinger, The Long Covid Handbook translates cutting-edge science, patient-led research and practical guidance with clarity. This book will equip you with expert information and advice on: - Long Covid's 200 symptoms, which include fatigue, brain fog, breathlessness and more - Tips for recovery - Which treatments are most effective and why - Who is most susceptible to the condition and why - What we can learn about Long Covid from other chronic illnesses - The impact on mental health This is the essential guide for anyone living with the condition, as well as clinicians seeking to better understand this little-understood illness.

The Covid-19 Reader - The Science and What It Says About the Social (Hardcover): William Cockerham, Geoffrey Cockerham The Covid-19 Reader - The Science and What It Says About the Social (Hardcover)
William Cockerham, Geoffrey Cockerham
R4,804 Discovery Miles 48 040 Ships in 12 - 17 working days

This reader offers some of the most important writing to date from the science of COVID-19 and what science says about its spread and social implications. The readings have been carefully selected, introduced, and interpreted for an introductory or graduate student readership by a distinguished medical sociology and political science team. While some of the early science was inaccurate, lacking sufficient data, or otherwise incomplete, the author team has selected the most important and reliable early work for teachers and students in courses on medical sociology, public health, nursing, infectious diseases, epidemiology, anthropology of medicine, sociology of health and illness, social aspects of medicine, comparative health systems, health policy and management, health behaviors, and community health. Global in scope, the book tells the story of what happened and how COVID-19 was dealt with. Much of this material is in clinical journals, normally not considered in the social sciences, which are nonetheless informative and authoritative for student and faculty readers. Their selection and interpretation for students makes this concise reader an essential teaching source about COVID-19. An accompanying online resource on the book's Routledge web page will update and evolve by providing links to new readings as the science develops.

Allergy and Respiration (Hardcover, 1st ed. 2016): Mieczyslaw Pokorski Allergy and Respiration (Hardcover, 1st ed. 2016)
Mieczyslaw Pokorski
R4,138 Discovery Miles 41 380 Ships in 10 - 15 working days

Allergy is an increasing health issue. It often targets the respiratory tract and entwines with respiratory ailments, which makes it difficult to discern the cause-effect linkage. Nonetheless, measures to counter the allergic background are a linchpin in preserving respiratory health. This book is an update on current advances in clinical and basic science on allergy and related topics. The diagnostics of allergy requires a multidisciplinary approach, including molecular examinations aimed at unraveling the intracellular control cascades. Chapters give insight into the innovations concerning modern pulmonary function tests, discuss pharmacological paradigms, and tackle the overlapping infectious aspects and clinical symptoms and markers. Environmental and genetic factors elicit a spectrum of inflammatory phenotypes linked to differential body responses to allergic perturbations. The book is intended for healthcare professionals, notably pulmonologists, primary care physicians, and medical researchers.   

Histamine and Histamine Receptors in Health and Disease (Hardcover, 1st ed. 2017): Yuichi Hattori, Roland Seifert Histamine and Histamine Receptors in Health and Disease (Hardcover, 1st ed. 2017)
Yuichi Hattori, Roland Seifert
R9,662 Discovery Miles 96 620 Ships in 10 - 15 working days

This book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview on the field. This chapter will also link the book to the previous HEP volume on histamine receptors and the recent HEP volume on the pharmacology of itch. Great attention will be paid to complementation of existing literature while avoiding undue duplication. The book will cover new methods for analysis of histamine and histamine metabolites, development of methods for histamine receptor analysis, signal transduction, histamine release, regulation of immune cells by histamine, histamine metabolism and associated diseases, regulation of major organ systems by histamine and development of new drugs and experimental tools for the study of histamine receptors.

New Insights on Antiviral Probiotics - From Research to Applications (Hardcover, 1st ed. 2017): Imad Al Kassaa New Insights on Antiviral Probiotics - From Research to Applications (Hardcover, 1st ed. 2017)
Imad Al Kassaa
R4,033 R3,485 Discovery Miles 34 850 Save R548 (14%) Ships in 12 - 17 working days

This book focuses on probiotics with antiviral activities. The "antiviral probiotic" is a new concept in medical sciences. Recently, studies have shown that antiviral probiotics can fight or prevent viral infections in many ways. The immunomodulation of mucosal immunity, production of antiviral compounds, virus trapping and the use thereof as vaccination vectors are the principal modes of action of antiviral probiotics. The author dedicates an entire chapter of the book to discussing the methods and techniques used to assess the antiviral activity of probiotic strains and their metabolites.

Suppression and Regulation of Immune Responses - Methods and Protocols, Volume II (Hardcover, 1st ed. 2016): Maria Cristina... Suppression and Regulation of Immune Responses - Methods and Protocols, Volume II (Hardcover, 1st ed. 2016)
Maria Cristina Cuturi, Ignacio Anegon
R4,590 R3,833 Discovery Miles 38 330 Save R757 (16%) Ships in 12 - 17 working days

This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice regulatory macrophages; recent advances in the treatment of immune-mediated inflammatory disorders; and novel mechanisms and therapeutic perspectives on food allergies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II is a great resource for current research and inspiration for new studies in immune tolerance.

Bacterial Persistence - Methods and Protocols (Hardcover, 1st ed. 2016): Jan Michiels, Maarten Fauvart Bacterial Persistence - Methods and Protocols (Hardcover, 1st ed. 2016)
Jan Michiels, Maarten Fauvart
R2,978 Discovery Miles 29 780 Ships in 10 - 15 working days

This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in Escherichia coli cultures, protocols for the determination of the persister subpopulation in Candida albicans, quantitative measurements of Type I and Type II persisters using ScanLag, to in vitro and in vivo models for the study of the intracellular activity of antibiotics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Persistence: Methods and Protocols brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.

Neuroimmune Pharmacology (Hardcover, 2nd ed. 2017): Tsuneya Ikezu, Howard E. Gendelman Neuroimmune Pharmacology (Hardcover, 2nd ed. 2017)
Tsuneya Ikezu, Howard E. Gendelman
R9,074 Discovery Miles 90 740 Ships in 10 - 15 working days

The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.

Immune Metabolism in Health and Tumor (Hardcover, 1st ed. 2017): Bin Li, Fan Pan Immune Metabolism in Health and Tumor (Hardcover, 1st ed. 2017)
Bin Li, Fan Pan
R6,095 Discovery Miles 60 950 Ships in 10 - 15 working days

This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain quiescent in the absence of challenges. Immune cells rely on metabolic pathways to adapt to changing environments and stimuli. Additionally, these cells can be modified in function or fate by fluctuations in available nutrients. The chapters in this book describe ways in which immune cells utilize and are regulated by metabolic pathways. Topics include how immune-cell metabolism shapes immune homeostasis, and how dysregulation of these pathways can lead to immune disorders. In different contexts, such as a tumor microenvironment, immune-cell function and identity may be modified not only by cytokines and checkpoint molecules, but also by nutrient availability and other metabolic stimuli. Transcriptional reprogramming confers many of the changes in immune cell metabolism that are seen when a T-cell, for example, undergoes activation or functional adaptation to different environments. Lastly, immune cells can destructively or protectively participate in human metabolic homeostasis or disorders. This book summarizes immune-metabolism from a variety of different perspectives, including the ways in which metabolic cues, pathways, and requirements of immune cells change in conditions of homeostasis and activation. The exploration of the significance of metabolic checkpoints and other cues, particularly in the context of cancer and immune disorders, may form the foundation for the development of therapeutics.

Monographs in Contact Allergy, Volume 4 - Systemic Drugs (Hardcover): Anton C.De Groot Monographs in Contact Allergy, Volume 4 - Systemic Drugs (Hardcover)
Anton C.De Groot
R5,531 Discovery Miles 55 310 Ships in 12 - 17 working days

This fourth volume in an exciting and detailed series on contact allergens and drug allergy provides monographs of all 507 systemic drugs which have caused delayed-type cutaneous drug hypersensitivity reactions and/or occupational allergic contact dermatitis. The monographs present: Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity. Key Features: Presents monographs of all known systemic drugs which have caused delayed allergic cutaneous drug reactions and/or occupational allergic contact dermatitis Provides an extensive literature review of relevant topics of allergenic systemic drugs, part of which is hard or impossible to find in database searches Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents immediate contact reactions (contact urticaria) from systemics drugs and delayed-type hypersensitivity in drugs caused only by cross-reactivity Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy

Introduction to Molecular Vaccinology (Paperback, 1st ed. 2016): Matthias Giese Introduction to Molecular Vaccinology (Paperback, 1st ed. 2016)
Matthias Giese
R3,286 Discovery Miles 32 860 Ships in 10 - 15 working days

This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

Structural Biology of the Complement System (Paperback): Dimitrios Morikis, John D. Lambris Structural Biology of the Complement System (Paperback)
Dimitrios Morikis, John D. Lambris
R1,787 Discovery Miles 17 870 Ships in 12 - 17 working days

Of recent, the structure of the complement system has received considerable attention, including the publication of several three-dimensional structures of complement proteins. This has led to the need for an authoritative resource to provide a complete overview of the basics, as well as an explanation of the cutting-edge work being accomplished in this emerging science. Structural Biology of the Complement System is devoted to the full exploration of structural aspects of the complement system, with special consideration of the links between molecular structure and function. Containing the work of leading authorities across the disciplines of immunology and structural biology, the book serves both as an introductory volume for newcomers to the field and as a comprehensive reference for established researchers, in particular those whose goal is the discovery of anticomplement drugs. Written in a didactic style, this volume is an appropriate resource for students in the fields of immunology and structural biology. Structural Biology of the Complement System comes with downloadable resources containing color figures, a molecular structure visualization program, and files with three-dimensional coordinates of the structures described in the book. These tools allow readers to perform tailored structural manipulation and analysis, while also serving as a starting point for further research.

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