The Guide to AIDS is succinct review of HIV/AIDS from a human-interest perspective. Chapters focus on some of the common patterns and prevention of HIV transmission and debunks misconceptions about HIV and AIDS. Brief descriptions the human immune system and epidemiology of HIV are included. The cultural component of disease, treatment and living with AIDS is central to much of this guide intended to synthesize, explain and de-mystify HIV and AIDS.

Examines how conspiracy theories and related forms of misinformation and disinformation about the Covid-19 pandemic have circulated widely around the world. Commissioned by recognised experts on area studies and conspiracy theories, making use of the existing COMPACT (Comparative Analysis of Conspiracy Theories) network run by Butter and Knight. Presents case studies on how Covid conspiracism has played out, using a range of methods from a variety of disciplinary perspectives.

Integrates the latest advances in polysaccharide chemistry and structure analysis, with the practical applications of polysaccharides in medicine and pharmacy, highlighting the role of glycoconjugates in basic biological processes and immunology. It also presents recent developments in glycobiology and glycopathology. The work covers bacterial, fungal and cell-wall polysaccharides, microbial and bacterial exopolysaccharides, industrial gums, the biosynthesis of bacterial polysaccharides, and the production of microbial polysaccharides.

This is a review of what needs to be done to realize the potential of monoclonal antibodies. It assesses the competing technologies with advice on the best approach for a particular situation. Monoclonal antibodies have revolutionized immunology and are now promising to have a similar impact on clinical medicine. Recent developments should overcome many of the difficulties experienced in the past which has seen a great deal of talk about the therapeutic applications of monoclonal antibodies, but very little routine therapy.

This book provides a comprehensive overview of antibody technology. It discusses in detail the new generation of engineered antibodies and the latest developments in immunoassay techniques and applications, as well as describing conventional methods of antibody production and use. Antibody Technology will bring the reader up-to-date with current methods, helping the reader to make informed decisions on the best approach to a given task with regard to cost, time and final application.

"This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease. Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo "

Essential Oils: Contact Allergy and Chemical Composition provides a full review of contact allergy to essential oils along with detailed analyses of the chemical composition of essential oils known to cause contact allergy. In addition to literature data, this book presents the results of nearly 6,400 previously unpublished sample analyses, by far the largest set of essential oils analyses ever reported in a single source of scientific literature. Covering 91 essential oils and two absolutes, the book presents an alphabetical list of all 4,350 ingredients that have been identified in them, a list of chemicals known to cause contact allergy and allergic contact dermatitis, and tabular indications of the ingredients that can be found in each essential oil. The book discusses contact allergy and allergic contact dermatitis for each of the oils and absolutes, sometimes able to provide only one or two reports but drawing upon considerable amounts of literature in other cases, such as with tea tree oil, ylang-ylang oil, lavender oil, rose oil, turpentine oil, jasmine absolute, and sandalwood oil. While limited information on the main components and their concentrations would be enough for most dermatologists, this book gives extensive coverage not only to improve levels of medical knowledge and quality of patient care, but also for the benefit of professionals beyond clinical study and practice, such as chemists in the perfume and cosmetics industries, perfumers, academic scientists working with essential oils and fragrances, aromatherapists, legislators, and those involved in the production, sale, and acquisition of essential oils. Key Features: Provides a full literature review of contact allergy to and chemical composition of 91 essential oils and two absolutes Presents the largest set of analytical reports on essential oils in scientific literature to date Provides tables of all chemicals which can be found in each essential oil with concentrations Presents an alphabetical list of 4,350 ingredients identified in the oils and absolutes with their synonyms and specifying in which oils each chemical can be present Provides a tabular list of all known allergens to the oils discussed Includes reference tables on the quantitative composition of essential oils that are of regulatory use to the fragrance industry Covers an extensive amount of information to benefit non-medical professionals involved with the research, production, distribution, and use of essential oils and products containing essential oils

Based on a Tumor Immunology Symposium held in Pittsburgh, this work provides comprehensive coverage of the most important aspects of tumor immunology. It reveals novel approaches to the immunotherapy of cancer and presents complex issues in an accessible manner.

This book presents current recommendations for vaccination for pre- and post-exposure prophylaxis in all suitable target populations and groups. It provides immunization guidelines from the Occupational Safety and Health Administration for health care workers and others at occupational risk of exposure and for routine vaccinations by the Immune Practices Advisory Committee of the Centers for Disease Control.;Covering all aspects of the production, testing and applications of Hepatitis B vaccines, this book: lists all available vaccines worldwide; discusses all serological assays in the field; examines how the vaccine was tested in international clinical trials; describes new programmes for universal immunization of infants; and reveals how the vaccine may prevent some forms of hepatocellular carcinoma.;The book should be of interest to: infectious disease specialists, clinical virologists, immunologists, haematologists, oncologists, hepatologists and gastroenterologists, paediatricians, pharmacologists, molecular biologists, biochemists, biotechnologists, genetic engineers, occupational safety administrators and public health specialists; and upper level undergraduate, graduate and medical school students of these disciplines.

This book demonstrates that nutrients play a direct role as co-factors and regulators of the immune system. The book also shows that modulating the immune response with nutrients can provide a fundamental approach to preventive medicine.;Containing nearly 2300 bibliographic citations as well as illustrative figures, tables, and micrographs, this book is designed to be of interest to clinical immunologists, immunology and vitamin researchers, nutrition specialists, paediatricians, neonatologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.

Exercise and Disease reviews the role of exercise and physical fitness in the prevention or causation of cancer. Relevant mechanistic studies, particularly immunomodulation, are emphasized. The book also interprets effects of long-term exercise on immune functions and data that shows how exercise influences disease resistance. On the other hand, exercise may be involved in immune mediated motion injuries. Finally, exercise plays a potential role in cancer therapy. The book will be useful to researchers interested in the most recent developments and their interpretations.

This reference spotlights the immunologic aspects of applying interferon-gamma to the treatment of infectious diseases - revealing the current knowledge of the biology and potential utility of interferon-gamma.;Written by more than 30 leading investigators in the field, Anti-Infective Applications of Interferon-Gamma: presents information according to specific patient populations and pathogens; focuses on only the most promising of emerging therapeutic agents; furnishes a detailed update of the pleiotropic role of interferon-gamma in host defense; and studies clinical and preclinical experiences in a broad variety of disease indications.;Containing over 900 bibliographic citations for further research, this book should be useful for infectious disease specialists, pharmacologists, immunologists, surgeons, pediatricians, parasitologists, hematologists, virologists, microbiologists, pathologists, oncologists and tropical medicine specialists.

Serving as a complementary series to AIDS Research Reviews - edited by Drs. Wayne C. Koff, Flossie Wong-Staal, and Ronald C. Kennedy (Marcel Dekker, Inc.) - this new series reviews significant advances in immunization research and addresses scientific and public policy challenges for moving candidate vaccines from the laboratory to the population.;Exploring recent progress in immunology, vaccine development and improvement, and clinical trials, Vaccine Research and Developments: analyzes the capacity of lipophilic components to chemically modify peptide and protein antigens and augment their immunogenicity; discusses the potential of noninfectious packaging mutants to serve as prototype vaccines; provides a novel presentation system for peptide vaccines through the multiple antigen peptide approach; examines the current status and future prospects for contraceptive vaccines and offers perspectives for improving pertussis vaccines; furnishes a comprehensive update of vaccine clinical trials; and describes the legal policy aspects involved in developing HIV vaccines.;Containing over 915 useful references, Vaccine Research and Developments is for immunologists, microbiologists and virologists, molecular and cell biologists, infectious disease specialists, pharmacologists, government and industry drug regulatory personnel, and graduate level students in these disciplines.

Along with Why I Am Not a Christian, this essay must rank as the most articulate example of Russell's famed atheism. It is also one of the most notorious. Used as evidence in a 1940 court case in which Russell was declared unfit to teach college-level philosophy, What I Believe was to become one of his most defining works. The ideas contained within were and are controversial, contentious and - to the religious - downright blasphemous. A remarkable work, it remains the best concise introduction to Russell's thought.

Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

Topics in Vaccine Adjuvant Research provides a concise, focused review of the immunological basis of adjuvant activity. The first section of the book contains several chapters that discuss key issues in cellular immunology, such as antigen processing and presentation, cytokine regulation of immune responses, and mucosal immunology. The second section consists of brief chapters on the mechanism of action of several adjuvants, including IL-2, nonionic block polymers, and cholera toxin. The major goals of this book are to define what is known about the mechanisms of adjuvant activity, show how research in cellular immunology can be used to help understand adjuvant action, and define possible areas where adjuvants might be useful probes for dissecting basic immunological processes. Immunologists, microbiologists, and infectious disease researchers will find this book an invaluable addition to their reference library.

Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex MHC; elucidation of its gene structure and polymorphism, as well as the molecular basis of MHC restriction; the arrangement, expression, and regulation of immunoglobulins; definition of the structure of the T cell receptor and organization of its genes; and the characterization of soluble factors involved in cell/cell interactions and cloning of their genes are among the major accomplishments. Volumes I and II build on these developments in basic immunology to introduce animal models of various diseases, corresponding human studies, and the genetic analysis of autoimmune traits at the patient population level. The book will be a tremendous asset to immunologists, geneticists, and physicians in various areas of clinical subspecialties.

Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex

Updated to reflect changes in the field since publication of the first edition in 1979. Provides a detailed review of the methodology available for assessing the diagnosis and prognosis of cancer patients including data on the application of tumor marker assays and other immunodiagnostic procedures

This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.

This volume presents the most complicated and powerful cancer biotherapies developed. It provides an overview of human immune system function and the mechanisms by which adoptive cellular immunotherapies (ACI) harnesses the activity. The volume provides a vision on the developments in ACI.

This informative text is divided into eight chapters, each of which presents a comprehensive review of natural and acquired host defense mechanisms in a major mycotic disease. The chapters are written by distinguished scientists whose studies have contributed significantly to the understanding of the immunology of the mycoses. This text should provide a valuable reference for researchers, practicing clinicians, and new investigators entering this expanding field.

This book explores the important role of the interferons in infections due to nonviral intracellular pathogens. It deals with the induction of interferons by a variety of intracellular microorganisms and the effects of interferons on the host cells and the microorganisms.

An eye-opening investigation - combining reporting, history and cutting-edge science - into allergies and their rise in recent decades Hay fever. Peanut allergies. Eczema. Billions of people worldwide have some form of allergy; millions have one severe enough to seriously endanger their health. And over the past decade, the number of people diagnosed with allergy has been steadily increasing, an ever-growing medical burden on individuals, families, and our health care system. Medical anthropologist Theresa MacPhail, herself an allergy sufferer whose father died of a bee sting, set out to understand why. The result is a holistic and deeply researched examination of allergies, from their first medical description in 1819 to the mind-bending new treatments that are giving patients hope. MacPhail spent years interviewing hundreds of experts, patients and activists, in an effort to understand how recent changes in our environment and lifestyle are contributing to the dramatic rise in cases globally. Pollution, chemicals, antibiotics and, increasingly, climate change are all making our immune systems become more and more irritated. But, as she shows us in Allergic, understanding what is irritating us and why will help us to craft better environments in the future-so we can all breathe easier.

This book reviews the major biochemical and biological properties of the lactoperoxidase system including both the bovine milk and human salivary enzymes. It focuses on the basic chemistry of peroxidase-catalyzed reactions and clinical applications of peroxide system antimicrobial effects.