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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues
This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.
This book provides effective statistical analyses in benthic foraminiferal communities patterns and show solutions for sea-land processes and alterations caused by climate changes and other local (and global) environmental concerns. Our goal is to provide, through these chapters, the monitoring and forecasting of environmental impacts with accurate data. We identify global regions most subject to industrial pollution, contamination and sewage, identifying potential sites prone to accumulate organic matter, which effects erosion, deposition, ocean temperature and pH changes (warming, cooling, acidification), climate and sea-level changes. Benthic habitats, specifically foraminiferal (single celled microorganisms found in the water column and sediment) contribute to our understanding of local and global climate change that effect at risk communities. Derived through the accuracy of oceanographic climate science, allow us to predict with the intention to alleviate potential loss in coastal areas, which are, the most vulnerable to ocean warming, cooling, acidification, and sea-level rise impacts. We unravel the mystery of the Environmental Impacts and Climate Change, helping communities prepare, adjust, adapt, and minimize effects or remediate loss. We show how to pinpoint the most vulnerable and specific sites for economic and social damage and loss, using foraminifera, an inexpensive and easily handled proxy valuable for monitoring coastal and marine environmental stressors. The implications of those problems and the ability to forecast patterns on land are primary issues we address by studying marine sediment of beaches, estuaries, bays and deep water worldwide. Ecology, biology, life history, and taxonomy of modern Foraminifera allows us to examine the current and historical record of environmental change effects, and predict implications for future sea-level rise, and ocean patterns. The prediction of responses of interacting systems to these problems, and development of strategies is needed to inform leadership with the knowledge and data to effectively implement policy, making this book a very informative and significant contribution for researchers and decision makers.
This book focuses on the spatial distribution of landslide hazards of the Darjeeling Himalayas. Knowledge driven methods and statistical techniques such as frequency ratio model (FRM), information value model (IVM), logistic regression model (LRM), index overlay model (IOM), certainty factor model (CFM), analytical hierarchy process (AHP), artificial neural network model (ANN), and fuzzy logic have been adopted to identify landslide susceptibility. In addition, a comparison between various statistical models were made using success rate cure (SRC) and it was found that artificial neural network model (ANN), certainty factor model (CFM) and frequency ratio based fuzzy logic approach are the most reliable statistical techniques in the assessment and prediction of landslide susceptibility in the Darjeeling Himalayas. The study identified very high, high, moderate, low and very low landslide susceptibility locations to take site-specific management options as well as to ensure developmental activities in theDarjeeling Himalayas. Particular attention is given to the assessment of various geomorphic, geotectonic and geohydrologic attributes that help to understand the role of different factors and corresponding classes in landslides, to apply different models, and to monitor and predict landslides. The use of various statistical and physical models to estimate landslide susceptibility is also discussed. The causes, mechanisms and types of landslides and their destructive character are elaborated in the book. Researchers interested in applying statistical tools for hazard zonation purposes will find the book appealing.
This book highlights the latest findings on fundamental aspects of composting, the interaction of various microorganisms, and the underlying mechanisms. In addition to addressing modern tools and techniques used for composting research, it provides an overview of potential composting applications in both agriculture and environmental reclamation. Composting is the process of organic waste decomposition, mediated by microorganisms. The end-product is called 'compost' and can be used as a supplement to improve soil fertility. As the municipal waste generated in most developing countries contains a substantial amount of organic matter suitable for composting, this technology offers a win-win opportunity for stakeholders in terms of disposing of organic waste and providing organic fertilizers for agriculture. In addition, using compost reduces the dependency on harmful chemical fertilizers, and represents a sustainable and environmentally friendly alternative.
Various "omics" methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance. While there are numerous scientific publications on "omics" applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of "omics" technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.
The lake charr Salvelinus namaycush is a ubiquitous member of cold-water lake ecosystems in previously glaciated regions of northern continental U.S., Alaska, and Canada that often support important commercial, recreational, and subsistence fisheries. The lake charr differs from other charrs by its large size, longevity, iteroparity, top-predator specialization, reduced sexual dimorphism, prevalence of lacustrine spawning, and use of deepwater habitat. The species is remarkably variable in phenotype, physiology, and life history, some of which is reflected in its ecology and genetics, with as many as four morphs or ecotypes co-occurring in a single lake. The lake charr is often the top predator in these systems, but is highly adaptable trophically, and is frequently planktivorous in small lakes. The lake charr by their name highlights their common habitat, lakes both large and small, but often frequents rivers and occasionally moves into the Arctic Ocean. Movement and behaviour of lake charr are motivated by access to cool, well-oxygenated water, foraging opportunities, predator avoidance, and reproduction. Owing to their broad distribution and trophic level, the lake charr serves as a sentinel of anthropogenic change. This volume will provide an up-to-date summary of what is currently known about lake charr from distribution to genetics to physiology to ecology. The book provides a compilation and synthesis of available information on the lake charr, beginning with an updated distribution and a revised treatment of the paleoecology of the species. Understanding of ecological and genetic diversity and movement and behaviour of the species has advanced remarkably since the last major synthesis on the species over 40 years ago. Mid-sections of the book provide detailed accounts of the biology and life history of the species, and later sections are devoted to threats to conservation and fishery management practices used to ensure sustainability. A new standard lake charr-specific terminology is also presented. The book will be a valuable reference text for biologists around the world, ecologists, and fishery managers, and of interest to the angling public.
An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition.
Human sexual nature today experiences many unanswered questions. Why does woman respond more slowly than man in arousal? What is the significance of the human orgasm? Why does sexual experience so often fail to form a lasting relationship? When is the most vulnerable time for a relationship in the process of formation? These and other questions are supported to find answers in our evolutional history. In this wide ranging and penetrating study the author finds human sexual nature to be basically inclined to committed relationships. The deepest evolutional trend, having early vertebrate origins, he finds to be the increasing biological investment in the unit young of each new generation.
This book addresses the problem of EEG signal analysis and the need to classify it for practical use in many sample implementations of brain-computer interfaces. In addition, it offers a wealth of information, ranging from the description of data acquisition methods in the field of human brain work, to the use of Moore-Penrose pseudo inversion to reconstruct the EEG signal and the LORETA method to locate sources of EEG signal generation for the needs of BCI technology. In turn, the book explores the use of neural networks for the classification of changes in the EEG signal based on facial expressions. Further topics touch on machine learning, deep learning, and neural networks. The book also includes dedicated implementation chapters on the use of brain-computer technology in the field of mobile robot control based on Python and the LabVIEW environment. In closing, it discusses the problem of the correlation between brain-computer technology and virtual reality technology.
This book describes how the genome sequence contributes to our understanding of allopolyploidisation and the genome evolution, genetic diversity, complex trait regulation and knowledge-based breeding of this important crop. Numerous examples demonstrate how widespread homoeologous genome rearrangements and exchanges have moulded structural genome diversity following a severe polyploidy bottleneck. The allopolyploid crop species Brassica napus has the most highly duplicated plant genome to be assembled to date, with the largest number of annotated genes. Examples are provided for use of the genome sequence to identify and capture diversity for important agronomic traits, including seed quality and disease resistance. The increased potential for detailed gene discovery using high-density genetic mapping, quantitative genetics and transcriptomic analyses is described in the context of genome availability and illustrated with recent examples. Intimate knowledge of the highly-duplicated gene space, on the one hand, and the repeat landscape on the other, particularly in comparison to the two diploid progenitor genomes, provide a fundamental basis for new insights into the regulatory mechanisms that are coupled with selection for polyploid success and crop evolution.
Egyptian coastal lakes and wetlands are among the most productive wetland ecosystems in the world. This volume explores their current status and how it can be maintained and improved. It describes the five Northern coastal lakes, their origin, physical and chemical properties and current development activities, and discusses the challenges facing these lakes, such as shrinking, pollution, degradation, and adaptive management. Further topics include hydrodynamics and modeling techniques, as well as strategies for the sustainable development of these valuable resources. The book closes with a concise summary of the conclusions and recommendations presented in the chapters. As such, it offers an invaluable resource for the academic community and postgraduate students, as well as for environmental managers and policymakers.
Cryonics-also known as cryopreservation or cryosuspension-is the preservation of legally dead individuals at ultra-low temperatures. Those who undergo this procedure hope that future technology will not only succeed in reviving them, but also cure them of the condition that led to their demise. In this sense, some hope that cryopreservation will allow people to continue living indefinitely. This book discusses the moral concerns of cryonics, both as a medical procedure and as an intermediate step toward life extension. In particular, Minerva analyses the moral issues surrounding cryonics-related techniques (including the hypothetical cryosuspension of fetuses as an alternative to abortion) by focusing on how they might impact the individuals who undergo cryosuspension, as well as society at large.
The study of ecosystems, fundamental to ecology, has been complemented by the growing field of landscape ecology. Ecosystem Function in Heterogeneous Landscapes addresses how interactions among ecosystems affect the functioning of individual ecosystems and the larger landscape. This groundbreaking synthesis unites ecosystem ecology's knowledge of system function with landscape ecology's knowledge of spatial structure. Practical concerns about scaling up from individual ecosystems to larger landscapes require an understanding of how networks of interacting ecosystems function together. The book elucidates the challenges faced by ecosystem scientists working in spatially heterogeneous systems, relevant conceptual approaches used in other disciplines and in different ecosystem types, and the importance of spatial heterogeneity in conservation resource management. The distinguished authors discuss how how much heterogeneity needs to be taken into account for specific types of scientific and management issues. Their chapters cover the spectrum from proposing novel conceptual approaches to detailing the practical implications of heterogeneous landscapes for fire management, water management and conservation planning.
In this book, leading experts in the field review how circadian rhythms impact the brain. An essential function of mammalian life is the exploitation of the regularities provided by the 24-hour cycle of day and night. The development and evolution of circadian clock mechanisms have allowed us to optimally adapt our behavior and physiology to the external world. Not surprisingly, a growing body of evidence links the disruption of circadian rhythms by genetic, lifestyle and environmental factors to illnesses of the brain. In the first section of the book, readers will learn about the molecular and anatomic architecture of circadian function in mammals. The ways in which environmental disruptions and misalignments can influence such mechanisms and therefore impair brain function and health status are also addressed. In the second part, the focus shifts to those brain regions responsible for brain function and the body-wide regulation of circadian function. Amongst others, special attention is paid to the role of astrocytes and the brain's reward and hyprocretin / orexin systems. The book concludes with an extensive discussion on the consequences of circadian rhythm dysfunction. Several chapters present the latest findings on Attention Deficit Hyperactivity Disorder, schizophrenia, autism spectrum disorder, drug abuse and mood disorders. Written by auhorities in the field, the book provides a state-of-the-art review of the latest findings on circadian clocks in the brain and highlights their potentially far-reaching impacts on our health and well-being. As such, it is essential reading for all neuroscientists and clinicians seeking to understand the intricate connections between circadian rhythms and brain health and illness.
This thesis provides a novel methodological basis for mechanistically understanding the dynamics of chemicals in products (CiPs) in the anthroposphere and physical environment and establishes a modeling continuum from production of a chemical to its concentrations in various environmental compartments. Using this framework, the thesis investigates how CiPs are transported and transformed and how they accumulate in the global environment. Furthermore, it identifies the measures needed to minimize their adverse effects on the environment and human society. It serves as an invaluable, interdisciplinary reference resource for industrial ecologists, environmental chemists and decision-makers involved in environmentally sound management of CiPs and associated waste.
Brain Protection Strategies and Nanomedicine, Volume 266 in the Progress in Brain Research serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology: Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy, Ultra Early Molecular Biologic Diagnosis Of Malignant And Neurodegenerative Diseases By The Immunospecific Profiles Of The Proteins Markers Of The Surface Of The Mobilized Autologous Hematopoietic Stem Cells, Neuroprotective effects of Insulin like growth factor-1 on Engineered metal Nanoparticles Ag, Cu and Al induced blood-brain barrier breakdown, and more. Other chapters cover how Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude: Neuroprotective effects of nanodelivery of a potent antioxidant compound H-290/51, Effectiveness of bortezomib and temozolomide for eradication of recurrent human glioblastoma cells, resistant to radiation, and more.
This book presents a comprehensive and innovative understanding of the role of shallow coastal ecosystems in carbon cycling, particularly marine carbon sequestration. Incorporating a series of forward-looking chapters, the book combines thorough reviews of the global literature and regional assessments-mainly around the Indo-Pacific region and Japan-with global perspectives to provide a thorough assessment of carbon cycling in shallow coastal systems. It advocates the expansion of blue-carbon ecosystems (mangroves, seagrass meadows, and salt marshes) into macroalgal beds, tidal flats, coral reefs, and urbanized shallow waters, demonstrating the potential of these ecosystems as new carbon sinks. Moreover, it discusses not only topics that are currently the focus of blue-carbon studies, i.e., sedimentary carbon stock and accumulation rate, but also CO2 gas exchange between the atmosphere and shallow coastal ecosystems, carbon storage in the water column as refractory organic carbon, and off-site carbon storage. Including highly original contributions, this comprehensive work inspires research beyond the specific regions covered by the chapters. The suite of new concepts and approaches is refreshing and demonstrates that blue-carbon research is indeed a vibrant new field of research, providing deep insights into neglected aspects of carbon cycling in the marine environment. At the same time the book provides guidance for policy makers to deliver benefits to society, for example the inclusion of blue carbon as a carbon offset scheme or the Nationally Determined Contribution (NDC) in the Paris Agreement, and also for building resilience in coastal socio-ecosystems through better management. This book is intended for all those interested in the science and management of coastal ecosystems.
By far, the most widely used subjects in psychological and biological research today are rodents. Although rats and mice comprise the largest group of animals used in research, there are over 2,000 species and 27 families of rodents, living all over the world (except Antarctica) and thriving in many different habitat types. The vast environmental diversity that rodents face has led to numerous adaptations for communication, including vocalizing and hearing in both the sonic and ultrasonic ranges, effectively communicating in the open air and underground, and using vocalizations for coordinating sexual behavior, for mother-pup interactions, and for signaling an alarming situation to the group. Some rodent species have even developed foot drumming behaviors for communication. Comparative studies from around the globe, using both field and laboratory methodologies, reveal the vast differences in acoustic communication behavior across many rodent species. Some rodents are amenable to training and have been domesticated and bred purely for research purposes. Since the early 1900s, rats and mice have been indispensable to research programs around the world. Thus, much of what we know about hearing and vocalizations in rodents come from these two species tested in the laboratory. The sequencing of the mouse genome in 2002, followed by the rat genome in 2004, only increased the utility of these animals as research subjects since genetically engineered strains mimicking human diseases and disorders could be developed more easily. In the laboratory, rats and mice are used as models for human communication and hearing disorders and are involved in studies on hearing loss and prevention, hormones, and auditory plasticity, to name a few. We know that certain strains of mice retain hearing better than others throughout their lifespan, and about the genes involved in those differences. We know about the effects of noise, hormones, sex, aging, and circadian rhythms on hearing in mice and other rodents. We also know about normal hearing in many families of rodents, including the perception of simple and complex stimuli and the anatomy and physiology of hearing and sound localization. The importance of acoustic communication to these animals, as well as the significance of these mammals to biomedical research, are summarized in the chapters.
While cognitive informatics and natural intelligence are receiving greater attention by researchers, multidisciplinary approaches still struggle with fundamental problems involving psychology and neurobiological processes of the brain. Examining the difficulties of certain approaches using the tools already available is vital for propelling knowledge forward and making further strides. Innovations, Algorithms, and Applications in Cognitive Informatics and Natural Intelligence is a collection of innovative research that examines the enhancement of human cognitive performance using emerging technologies. Featuring research on topics such as parallel computing, neuroscience, and signal processing, this book is ideally designed for engineers, computer scientists, programmers, academicians, researchers, and students. |
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