Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.

Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

Genetic Engineering and Genome Editing for Zinc Biofortification of Rice provides the first single-volume, comprehensive resource on genetic engineering approaches, including novel genome editing techniques, that are carried out in rice, a staple crop for much of the world's population. Dietary zinc deficiency can lead to negative health outcomes, including increased risk of stunting, respiratory diseases, diarrhea, mortality during childhood, and preterm births in pregnancy. By providing a complete view of the need for zinc biofortification in rice, sections in this book discuss state-of-the-art scientific advances, and then go further, placing them in their proper scientific, regulatory and socioeconomic contexts. While zinc biofortification can be achieved through conventional breeding, genetic engineering and agronomic practices, this is the first reference to bring all the latest insights and understanding to a comprehensive resource that is based on real-world experience and targeted applications.

Colorectal Disorders and Diseases: An Infographic Guide provides a comprehensive and up-to-date overview of the most relevant diagnostic modalities, staging, classification systems and current therapeutic modalities for colorectal disorders and diseases. With coverage from incontinence, prolapse, anal fissures, and cancer, this reference offers a wide-ranging guide to colorectal disorders and diseases. The use of engaging infographics throughout provides an inviting "at-a-glace" perspective of the subject, allowing users to retain a large amount of information without the need to scroll through large text or complex algorithms. This is an important reference for clinicians, surgeons and medical students rotating in colorectal surgery as well as scientists that need a quick reference for research of colorectal issues including epidemiology, diagnosis and therapy.

Advances in Agronomy, Volume 156, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 145, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this volume presenting interesting chapters on the Blood-brain barrier breakdown and brain edema formation in Alzheimer’s disease, Blast brain Injury induced edema formation and therapeutic measures, Brain edema in Parkinson’s disease. Novel therapeutic strategies, Brain edema and blood-brain barrier breakdown in sleep deprivation. Therapeutic potential of cerebrolysin, Differential cell injury induced by NMDA antagonist MK 801 in early age, Anesthetics influence Brain edema in concussive head injury, and more.

Understanding the human mind and how it relates to the world that we experience has challenged philosophers for centuries. How then do we even begin to think about 'minds' that are not human? Science now has plenty to say about the properties of mind. In recent decades, the mind - both human and otherwise - has been explored by scientists in fields ranging from zoology to astrobiology, computer science to neuroscience. Taking a uniquely broad view of minds and where they might be found - including in plants, aliens, and God - Philip Ball pulls these multidisciplinary pieces together to explore what sorts of minds we might expect to find in the universe. In so doing, he offers for the first time a unified way of thinking about what minds are and what they can do, arguing that in order to understand our own minds and imagine those of others, we need to move on from considering the human mind as a standard against which all others should be measured, and to think about the 'space of possible minds'. By identifying and mapping out properties of mind without prioritizing the human, Ball sheds new light on a host of fascinating questions. What moral rights should we afford animals, and can we understand their thoughts? Should we worry that AI is going to take over society? If there are intelligent aliens out there, how could we communicate with them? Should we? Understanding the space of possible minds also reveals ways of making advances in understanding some of the most challenging questions in contemporary science: What is thought? What is consciousness? And what (if anything) is free will? The more we learn about the minds of other creatures, from octopuses to chimpanzees, and to imagine the potential minds of computers and alien intelligences, the greater the perspective we have on if and how our own is different. Ball's thrillingly ambitious The Book of Minds about the nature and existence of minds is more mind-expanding than we could imagine. In this fascinating panorama of other minds, we come to better know our own.

The lymphatic system develops and functions in parallel with the blood circulatory system (termed the "hemovasculature") and accomplishes transport of interstitial fluids, dietary lipids, and reverse transport of cholesterol, immune cells, and antigens-providing a critical homeostatic fluid balance and transmission of immune cells and mediators back to the cardiovascular system. Although the daily flow of lymph (normally 1-2 L/day under unstressed conditions) is far lower than that of daily blood flow (which is 7,500 L/day), without the adequate functioning of the lymphatics, virtually all organs and tissues would acutely suffer many different physical and inflammatory stresses ranging from edema to organ system failure. Although blood and lymphatic vessels often form in anatomic parallels to one another, our knowledge of the workings of the lymphatic system, the fine structure of lymphatic networks, how they function in different organs, and how they are regulated physiologically and immunologically are far from parallel; our knowledge of the lymphatic system still remains at only a tiny fraction of what is understood about the cardiovascular system. Although both the cardiovascular and lymphatic systems are important transport systems, what they transport and how they transport and propel these very different cargoes could not be more dissimilar. This book provides an overview of the history of the discovery (and re-discovery) of the components of the lymphatic system, lymphatic anatomy, physiological functions of lymphatics, molecular features of the lymphatic system, and clinical perspectives involving lymphatics which may be of interest to scientists, clinicians, patients, and the lay public. We provide a current understanding of some of the more important structural similarities and differences between lymphatics and the blood vascular system, their coordinated control by angiogenic and hemangiogenic growth factors and other modulators, the fate and lineage determinants which control lymphatic development, and the roles that lymphatics may play in several different diseases.

Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induced neurotoxicity: what we have learned from Caenorhabditis elegans models, and more.

Multicultural Implications of Neuroethics: Issues in the Application of Neuroscience underscores the need for theory, research, and cultural perspective within neuroethics to thoughtfully address the ethical issues that arise from the application of neuroscience on an international scale. The text introduces readers to essential concepts in neuroethics, including cultural neuroethics, the foundation of neuroscience, and methodological issues. Dedicated chapters explore the key principles of neuroethics and various theoretical perspectives, including Western, Eastern, and Middle Eastern views. Readers will examine neuroethics and cultural issues, including discussions of brain enhancement and personnel selection using neuroscience, application of neuroscience in education, brain and neurofeedback methods, treatment of psychiatric and mental health conditions using neuroscience, and the application of neuroscience in law. Closing chapters address topical issues including the future of neuroethics with discussions on the use of nanotechnology, cultural considerations of neuroethical applications, informed consent, and how best to advance neuroscience. Featuring cutting-edge, essential research, Multicultural Implications of Neuroethics is an exemplary text for students and professionals in psychiatry, psychology, neuroscience, neurology, counselor education, educational neuroscience, as well as any social science that integrates research and practices inspired by neuroscience.

Modern Intervention Tools for Rehabilitation addresses current advancements in rehabilitation to better equip clinicians and researchers in the field. This resource will equip professionals for better patient outcomes and improve future rehabilitation research quality. An interdisciplinary understanding of the rehabilitation field is crucial for improved patient care and outcomes, with relevance to patient care in other disciplines as well. With chapters dedicated to diagnostics, choosing appropriate techniques, managing medical treatment, and proper equipment care, readers will be well-equipped to decide on protocols, increase patient outcomes, and improve quality of life.

The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia.

Changing Climate and Resource Use Efficiency in Plants reviews the efficiencies for resource use by crop plants under different climatic conditions. This book focuses on the challenges and potential remediation methods for a variety of resource factors. Chapters deal with the effects of different climatic conditions on agriculture, radiation use efficiency under various climatic conditions, the efficiency of water and its impact on harvest production under restricted soil moisture conditions, nitrogen and phosphorus use efficiency, nitrogen use efficiency in different environmental conditions under the influence of climate change, and various aspects of improving phosphorus use efficiency. The book provides guidance for researchers engaged in plant science studies, particularly Plant/Crop Physiology, Agronomy, Plant Breeding and Molecular Breeding. In addition, it provides valuable insights for policymakers, administrators, plant-based companies and agribusiness companies.

Integrated Population Biology and Modeling: Part B, Volume 40, offers very delicately complex and precise realities of quantifying modern and traditional methods of understanding populations and population dynamics, with this updated release focusing on Prey-predator animal models, Back projections, Evolutionary Biology computations, Population biology of collective behavior and bio patchiness, Collective behavior, Population biology through data science, Mathematical modeling of multi-species mutualism: new insights, remaining challenges and applications to ecology, Population Dynamics of Manipur, Stochastic Processes and Population Dynamics Models: The Mechanisms for Extinction, Persistence and Resonance, Theories of Stationary Populations and association with life lived and life left, and more.

Cognitive Archeology, Body Cognition, and the Evolution of Visuospatial Perception offers comprehensive perspective on the role of brain form and function, body cognition, and visuospatial integration in the evolution of ancient and modern human species. The book covers evolutionary neuroanatomy, cognitive sciences, and experimental archaeology, providing a bridge between anthropology and evolutionary studies to neurosciences. Written by international experts in paleoanthropology and prehistoric archaeology, as well as neurobiology and psychology, the book explores how body perception and spatial capacity may have evolved to enhance a "prosthetic capacity" able to integrate the brain, body and technological discoveries into a single functional system. Chapters discuss the anatomy, function and evolution of the parietal cortex in human and non-human primates. In addition, the book covers the evolution of visuospatial cognition and how modern brain imaging can trace these changes back millions of years.

Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the enteric nervous system, specialised enteric glial cells maintain all aspects of gastrointestinal function. Then there are distinctive glial cells of the special senses that ensure how the body perceives and reacts to its environment. In pathology, neuroglia strive to protect the diverse cellular components of the nervous system and are responsible for a proactive programme of posttraumatic restructuring that is aimed at recovery of life-sustaining function. Neuroglia: Function and Pathology provides a highly original and comprehensive account of the physiology and pathophysiology of glial cells in the central and peripheral nervous systems. The first part of the book provides a far-reaching description of glial cell form and function, from their evolution in invertebrates to their complexity in humans, encompassing the developmental origin of the varied glial cell types and their diversity of morphology, molecular biology and cellular physiology. The second part of the book is devoted to an all-embracing evaluation of glial cell pathophysiology, commencing with definitive explanations of the fundamental pathologies of the main glial cell types, and ending in a systematic examination of glial contributions to specific neurological diseases. This book emphasises the central roles played by the different classes of neuroglial cells in the progression and outcome of neurological disorders of the central and peripheral nervous systems and highlights potential of glial cells as therapeutic targets. The book contains more than 2500 key references from over 150 years of glial research and is superbly illustrated with over 350 original and explanatory full colour figures that describe the diverse characteristics and properties of glial cells in health and disease. Under the same cover, this book combines an authoritative reference book for research and clinical neuroscientists and at the same time serves as an instructive textbook for students of neuroscience, from undergraduates to postgraduates.

Plant Development and Evolution, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Evolution of the plant body plan, Lateral root development and its role in evolutionary adaptation, the Development of the vascular system, the Development of the shoot apical meristem and phyllotaxis, the Evolution of leaf diversity, the Evolution of regulatory networks in land plants, The role of programed cell death in plant development, the Development and evolution of inflorescence architecture, the Molecular regulation of flower development, the Pre-meiotic another development, and much more.

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.

Effect of High-Pressure Technologies on Enzyme: Science and Applications provides a deep, practical discussion of high-pressure processing (HPP) and high-pressure homogenization (HPH) technologies and biochemical approaches, applied across research and industry, with applications ranging from food to pharmaceuticals and commercial enzyme production. Early chapters discuss foundational aspects of HPP and HPH approaches; the science of enzyme modification; and basic aspects of enzyme activity, stability, and structure as studied in biochemical processes. Later chapters consider the effect of HPP and HPH technologies and their mechanisms of controlling enzyme modification to improve enzyme performance for chosen applications. Special attention is paid to the application of HPP and HPH technologies and enzyme modifications in food processing, microbial enzyme modification, drug discovery, and production of other commercial enzymes, as well as the challenges of undesirable enzyme inactivation. The final chapter discusses future directions of the field and technologies, and expanded applications.