Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS: Part II, Volume 161, in the International Review on Neurobiology serial highlights new advances, with this volume presenting chapters on topics including Introduction to Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Peri-adolescent Exposure to (Meth)amphetamine in Animal Models, The Impact of Adolescent Nicotine Exposure on Alcohol Use During Adulthood: The Role of Neuropeptides, Cannabis Exposure During Adolescence: A uniquely Sensitive Period for Neurobiological Effects, The Stoned Age: Sex Differences in the Effects of Adolescent Cannabinoid Exposure on Prefrontal Cortex Structure and Function in Animal Models, and more.

Deep Learning in Bioinformatics: Techniques and Applications in Practice introduces the topic in an easy-to-understand way, exploring how it can be utilized for addressing important problems in bioinformatics, including drug discovery, de novo molecular design, sequence analysis, protein structure prediction, gene expression regulation, protein classification, biomedical image processing and diagnosis, biomolecule interaction prediction, and in systems biology. The book also presents theoretical and practical successes of deep learning in bioinformatics, pointing out problems and suggesting future research directions. Dr. Izadkhah provides valuable insights and will help researchers use deep learning techniques in their biological and bioinformatics studies.

Effects of Peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, Volume 161 in the International Review on Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Cannabis Exposure During Adolescence: A Uniquely Sensitive Period for Neurobiological Effects, The Stoned-Age: A Systematic Review of the Neurobiological Effects of Adolescent Cannabinoid Exposure on Preclinical Animal Models, Genetic Influences Impacting Nicotine Use and Abuse During Adolescence: Insights from Human and Animal Studies, the Impact of Adolescent Nicotine Exposure on Adulthood Alcohol Consumption: The Role of Neuropeptides, and much more. Additional chapters cover The Role of Sex in the Persistent Effects of Adolescent Alcohol Exposure on Behavior and Neurobiology in Rodents, The Effects of Peri-Adolescent Alcohol Use on the Developing Hippocampus, Regulation of Glutamate Signaling in the Extended Amygdala by Adolescent Alcohol Exposure, Peri-Adolescent Binge Drinking Effects on Hippocampal Neurogenesis, Neuroepigenetic Consequences of Adolescent Ethanol Exposure, Adolescent Neuroimmunity and Its Interaction with Alcohol, and much more.

The Volume Regulating Neuroethics: Transnational Legal challenges will focus on the new and fascinating ethical and legal challenges posed by neurotechnology and its global regulation. The Volume will address topics ranging from the foundations of neuroethics, free will and human liberty to their impact in criminal and civil liability, the legal regulation of biotechnological developments and its challenges for health, privacy and other fundamental human rights.

Viral Replication Enzymes and their Inhibitors, Part B, Volume 50 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics surrounding enzymes.

From rethinking feminist archives, to inserting postpornography in academia, to approaching sex toys from a transpositive perspective, to dismantling the foundations of techno-capitalism, the areas of inquiry in this book are lenses through which to explore the relationships between genders, bodies and technologies. All the various chapters work to reimagine the body as a hybrid, malleable and subversive source of potentiality. These essays offer readers road maps for unimagined and uncharted social scapes: the relationship between bodies-technologies-genders means working within a space of monstrosity. Through this embodied discomfort the book questions existing techno-social norms, and imagines tranfeminist futures. Contributors are: Carlotta Cossutta, Valentina Greco, Arianna Mainardi, Stefania Voli, Lucia Egana Rojas, Ludovico Virtu, Angela Balzano, Obiezione Respinta, Elisa Virgili, Rachele Borghi, and Diego Marchante "Genderhacker".

Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA following prolonged stress or trauma. This is accomplished through the evaluation of both the physiological and molecular effects of stress on the body that can eventually lead to stress disorders. The book begins by providing a psychiatric, biological, and phenomenological foundation for understanding stress disorders, before delving into the genomics of stress disorders. From here, chapter authors discuss a range of recent epigenetic research in the area, highlighting epigenome-wide association studies (EWAS), exciting developments in noncoding RNA studies, possible effects of prolonged stress on telomere shortening, and the long-term physical effects of PTSD on the health of patients. The book also examines the effect of adversity during sensitive periods or development and across the life span. The book concludes by looking at possible transgenerational stress-induced epigenetic alterations on future offspring and important areas of research for public health, along with the potential for epigenetic therapeutics or "epidrugs."

Advances in Agronomy, Volume 170, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics.

The Rise of Chance in Evolutionary Theory: A Pompous Parade of Arithmetic explores a pivotal conceptual moment in the history of evolutionary theory: the development of its extensive reliance on a wide array of concepts of chance. It tells the history of a methodological and conceptual development that reshaped our approach to natural selection over a century, ranging from Darwin's earliest notebooks in the 1830s to the early years of the Modern Synthesis in the 1930s. Far from being a "pompous parade of arithmetic," as one early critic argued, evolution transformed during this period to make these conceptual and technical tools indispensable. This book charts the role of chance in evolutionary theory from its beginnings to the earliest days of modern evolutionary theory, making it an ideal resource for evolutionary biologists, historians, philosophers, and researchers in science studies or biological statistics.

Nitrogen Assessment: Pakistan as a Case-Study provides a detailed overview of issues and challenges related to nitrogen use and overuse, thus serving as a reference for researchers in Pakistan and providing important insights for other geographic regions. Excess and inefficient nitrogen use in crops and livestock sectors is polluting our rivers, seas, atmosphere, and ecosystems, contributing to climate change, hampering biodiversity, and contributing to stratospheric ozone depletion. This book covers the importance of nitrogen in relation to food security, human health, and economic stability in South Asia. It also discusses nitrogen status, sources, sinks, and drivers of nitrogen use in Pakistan, focusing on current nitrogen measures and policies. Nitrogen pollution is one of the biggest challenges of 21st Century, and the international scientific community is beginning to recognize the significance of nitrogen pollution and to explore how to combat it. The editors' institution, University of Agriculture, Faisalabad, partners with South Asia Nitrogen Hub, which includes about 30 organizations from South Asia and UK working on nitrogen assessment, budgeting, awareness, and policy guidance, as well as possible measures to reduce nitrogen pollution. Nitrogen Assessment: Pakistan as a Case-Study provides an important guide to this work and is written in a way that is accessible to an audience with a wide range of experience from advanced students to seasoned researchers.

Body, Brain, Behavior: Three Views and a Conversation describes brain research on the frontiers, with a particular emphasis on the relationship between the brain and its development and evolution, peripheral organs, and other brains in communication. The book expands current views of neuroscience by illustrating the integration of these disciplines. By using a novel method of conversations between 3 scientists of different disciplines, cellular, endocrine, developmental, and social processes are seamlessly woven into topics that relate to contemporary living in health and disease. This book is a critical read for anyone who wants to become familiar with the inner workings of the nervous system and its intimate connections to the universe of contemporary life issues.

Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions.

International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Stress Tolerance in Horticultural Crops: Challenges and Mitigation Strategies explores concepts, strategies and recent advancements in the area of abiotic stress tolerance in horticultural crops, highlighting the latest advances in molecular breeding, genome sequencing and functional genomics approaches. Further sections present specific insights on different aspects of abiotic stress tolerance from classical breeding, hybrid breeding, speed breeding, epigenetics, gene/quantitative trait loci (QTL) mapping, transgenics, physiological and biochemical approaches to OMICS approaches, including functional genomics, proteomics and genomics assisted breeding. Due to constantly changing environmental conditions, abiotic stress such as high temperature, salinity and drought are being understood as an imminent threat to horticultural crops, including their detrimental effects on plant growth, development, reproduction, and ultimately, on yield. This book offers a comprehensive resource on new developments that is ideal for anyone working in the field of abiotic stress management in horticultural crops, including researchers, students and educators.

Advances in Botanical Research: Past, Current and Future Topics, Volume 100 in the Advances in Botanical Research series, celebrates a remarkable achievement as 100 volumes have now been published, with several others being prepared. New chapters in this monumental release include Editorial activities for Advances in Botanical Research, Revisiting ABR editing in the period 2006-2012: An exciting experience with Jean-Claude Kader, A tribute to the scientific contributions of Pierre Gadal and his laboratory, Evolution of Bacterial Phototrophy, Algae for Global Sustainability, Genomics of cyanobacteria: New insights and lessons for shaping our future, An overview of the root-knot-nematode compatible interaction, and more.

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice.

Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

Science for the Protection of Indonesian Coastal Ecosystems (SPICE) provides key information on all aspects related to the management of coastal ecosystems. This includes the coastal management involved, the ecology of this area, and the relationship between humans and the environment found here. The book presents guidelines defined by scientific experts, allowing for proper application of science products into ecosystem management. The bio-geo-physical importance of coastal ecosystems of Indonesia makes this a book of global importance and interest.

In recent times, the boundary between living and non-living has been blurred by advances in genomics, cell biology, and molecular neuroscience, whereby humans are repaired, enhanced, or made anew. Scientists and physicians are now able to keep cells, organs, and bodies alive indefinitely and can return cells or DNA to our bodies and make new cells for the purpose of treating disease or growing new tissue. Meanwhile, transhuman technologies create illusions of immortality. Immortal: Our Cells, DNA, and Bodies synthesizes what we know about life and death from a genetic, molecular, and cellular perspective, demarcates limits of knowledge, and poses new questions. Award-winning researcher and writer David Goldman examines in-depth three keys to understanding the nature and continuity of life: 1) epigenetic (ephemeral) vs genetic (durable) transgenerational memory; 2) life's cellular nature, and the ability to make bodies from cells; and 3) the distinction between bodies and persons. Grounded in recent scientific evidence and real-life cases that test our historical understanding of life and death, Goldman probes the nature of molecular continuity in the face of mortal extinction, encompassing how changes to the DNA code can be both long-lasting and transgenerational, and the continuous nature of cellular and molecular information transmission. In tying these themes together, Immortal asks us to apply fresh scientific concepts to examine, for ourselves, the continuity of being in the face of mortality.

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer's disease, Parkinson's disease, and Huntington's disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

Measuring and Modeling Persons and Situations presents major innovations and contributions on the topic, promoting deeper integration, cross-pollination of ideas across diverse academic disciplines, and the facilitation of the development of practical applications such as matching people to jobs, understanding decision making, and predicting how a group of individuals will interact with one another. The book is organized around two overarching and interrelated themes, with the first focusing on assessing the person and the situation, covering methodological advances and techniques for inferring and measuring characteristics, and showing how they can be instantiated for measurement and predictive purposes. The book's second theme presents theoretical models, conceptualizing how factors of the person and situation can help us understand the psychological dynamics which underlie behavior, the psychological experience of fit or congruence with one's environment, and changes in personality traits over time.

Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins.