Molecular Mechanisms of Nutritional Interventions and Supplements for the Management of Sexual Disfunction and Benign Prostatic Hyperplasia presents the epidemiologic data linking diet with BPH and ED, along with a deep explanation on why nutritional approaches and different macronutrients may modify the pathogenesis of the disease. Coverage includes the relevance/epidemiology of the disease, pathophysiological events causing the disease, available therapeutic options, molecular mechanisms of action of available treatments, epidemiological and intervention studies suggesting the benefit of diet as therapeutic option for BPH and ED, and potential mechanisms of action of nutritional based approaches as treatment for BPH and ED. By combining medicine, diet and lifestyle options, this title provides a truly multidisciplinary approach to BPH and ED, making it a unique resource for those treating BPH and an irreplaceable reference guide for those in research.

Retinal Computation summarizes current progress in defining the computations performed by the retina, also including the synaptic and circuit mechanisms by which they are implemented. Each chapter focuses on a single retinal computation that includes the definition of the computation and its neuroethological purpose, along with the available information on its known and unknown neuronal mechanisms. All chapters contain end-of-chapter questions associated with a landmark paper, as well as programming exercises. This book is written for advanced graduate students, researchers and ophthalmologists interested in vision science or computational neuroscience of sensory systems. While the typical textbook's description of the retina is akin to a biological video camera, the real retina is actually the world's most complex image processing machine. As part of the central nervous system, the retina converts patterns of light at the input into a rich palette of representations at the output. The parallel streams of information in the optic nerve encode features like color, contrast, orientation of edges, and direction of motion. Image processing in the retina is undeniably complex, but as one of the most accessible parts of the central nervous system, the tools to study retinal circuits with unprecedented precision are up to the task. This book provides a practical guide and resource about the current state of the field of retinal computation. Editorial Reviews: "...this book is also a unique overview of our current understanding of the why and the how of retinal computation and there is something here for anyone with a grounding in vision science who recognises that there is more to what the retina does than... meets the eye." -- Prof Steven Dakin, New Zealand Optics, May 28, 2022. "I want to commend Dr. Schwartz for assembling this incredible resource and strongly recommend Retinal Computation to everyone who is a student of vision. The vast majority of modern topics in retina are covered yet in a fashion that is clear, and concise. The book covers the cellular and circuit basis of computations ranging from those covered by most textbooks, such as center-surround receptive field or direction selectivity , to those you probably do not associated with the retina such as "motion anticipation" and "threat detection". Each chapter is self-contained, meaning you can easily "pick and choose" the topics. A quick perusal of the chapter titles are almost certainly going to pique your interest. For example, you may know that the retina has single photon sensitivity but do you know "How many photons does it take to create a percept"? (Chapter 1). How does the retina encode texture (i.e. spatial fluctuations within the receptive field)? (Chapter 7). Is object motion sensitivity related to Direction selectivity? (Chapter 12). The list goes on. This book will also serve as a great resource for those teaching advanced undergraduate or graduate level vision courses for students with backgrounds in experimental or computational vision science. Each chapter contains what Dr. Schwartz's considers a "landmark paper" in the field, with a set of questions that can be used as a guide for reading these papers. And finally he includes programming exercises that can be easily implemented in Matlab to address basic concepts introduced in the chapter. The instructions are detailed so that even those new to Matlab will be able to implement these exercises these straightforward. It is this combination - textbook chapter + primary literature + quantitative exercises that will solidify these concepts. There are many vision science topics not covered in the book. For example, there is little on retinal disease or development. But these limitations are far outweighed by where the book succeeds. The vast majority of the book is written by Dr. Schwartz, giving it a uniformity that is welcome. Despite tackling quite modern questions where there is ongoing progress, Dr.Schwartz has extracted what are key findings that are likely to stand the test of time. And finally, it is really interesting! For those who think that the retina is "solved", think again. Retinal computations is a fantastic way for all circuit neuroscientist to learn how much computations can be achieved with very few synapses." -- Marla B. Feller, Ph. D., Paul Licht Distinguished Professor in Biological Sciences, Division of Neurobiology, Department of Molecular and Cell Biology & Helen Wills Neuroscience Institute University of California, Berkeley "This fantastic new textbook from a rising star in the field clearly and thoroughly updates our picture of what the retina computes. It is detailed enough for senior researchers but also pedagogical, providing a go-to reference for students. The illustrations within the text and for the chapter headings are both beautiful and informative." -- Stephanie E. Palmer, Ph.D., Associate Professor, Department of Organismal Biology and Anatomy, Department of Physics, University of Chicago "This book summarizes the impressive recent progress in understanding how visual computations are performed by retinal circuits. The book is an important resource not only for retinal experts, but more generally for anyone seeking to explain how the brain works at the level of neural circuits. Greg Schwartz and his co-authors have made a major contribution to the field." -- Sebastian Seung, Anthony B. Evnin '62 Professor, Neuroscience Institute and Computer Science Dept., Princeton University "This is a wonderful book from a true expert in the retina field. It is a fantastic resource for researchers, lecturers, and students alike. The book nicely covers the many facets of how the retina processes the visual input that enters the eye. Despite the richness in material, the presentation manages to stay accessible and always connects back to fundamental questions of visual processing. Each chapter by itself is a great entry point into a particular area of how the neural network of the retina deals with a specific set of visual challenges. I have thoroughly enjoyed this wonderful overview of retinal computation, served on a silver platter, and I will use the book both as background material for research and as a resource for teaching. I particularly like the sets of exercises that conclude each chapter." -- Dr. Tim Gollisch, Professor for Sensory Processing in the Retina, Department of Ophthalmology, University Medical Center Goettingen

Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.

Fundamentals of Tropical Freshwater Wetlands: From Ecology to Conservation Management is a practical guide and important tool for practitioners and educators interested in the ecology, conservation and management of wetlands in tropical/subtropical regions. The book is written in such a way that, in addition to scientists and managers, it is accessible to non-specialist readers. Organized into three themed sections and twenty-three chapters, this volume covers a variety of topics, exposing the reader to a full range of scientific, conservation and management issues. Each chapter has been written by specialists in the topic being presented. The book recognizes that wetland conservation, science and management are interlinked disciplines, and so it attempts to combine several perspectives to highlight the interdependence between the various professions that deal with issues in these environments. Within each chapter extensive cross-referencing is included, so as to help the reader link related aspects of the issues being discussed.

Science for the Protection of Indonesian Coastal Ecosystems (SPICE) provides key information on all aspects related to the management of coastal ecosystems. This includes the coastal management involved, the ecology of this area, and the relationship between humans and the environment found here. The book presents guidelines defined by scientific experts, allowing for proper application of science products into ecosystem management. The bio-geo-physical importance of coastal ecosystems of Indonesia makes this a book of global importance and interest.

In recent times, the boundary between living and non-living has been blurred by advances in genomics, cell biology, and molecular neuroscience, whereby humans are repaired, enhanced, or made anew. Scientists and physicians are now able to keep cells, organs, and bodies alive indefinitely and can return cells or DNA to our bodies and make new cells for the purpose of treating disease or growing new tissue. Meanwhile, transhuman technologies create illusions of immortality. Immortal: Our Cells, DNA, and Bodies synthesizes what we know about life and death from a genetic, molecular, and cellular perspective, demarcates limits of knowledge, and poses new questions. Award-winning researcher and writer David Goldman examines in-depth three keys to understanding the nature and continuity of life: 1) epigenetic (ephemeral) vs genetic (durable) transgenerational memory; 2) life's cellular nature, and the ability to make bodies from cells; and 3) the distinction between bodies and persons. Grounded in recent scientific evidence and real-life cases that test our historical understanding of life and death, Goldman probes the nature of molecular continuity in the face of mortal extinction, encompassing how changes to the DNA code can be both long-lasting and transgenerational, and the continuous nature of cellular and molecular information transmission. In tying these themes together, Immortal asks us to apply fresh scientific concepts to examine, for ourselves, the continuity of being in the face of mortality.

Measuring and Modeling Persons and Situations presents major innovations and contributions on the topic, promoting deeper integration, cross-pollination of ideas across diverse academic disciplines, and the facilitation of the development of practical applications such as matching people to jobs, understanding decision making, and predicting how a group of individuals will interact with one another. The book is organized around two overarching and interrelated themes, with the first focusing on assessing the person and the situation, covering methodological advances and techniques for inferring and measuring characteristics, and showing how they can be instantiated for measurement and predictive purposes. The book's second theme presents theoretical models, conceptualizing how factors of the person and situation can help us understand the psychological dynamics which underlie behavior, the psychological experience of fit or congruence with one's environment, and changes in personality traits over time.

Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins.

The Physical Oceanography of the Arctic Mediterranean Sea describes the circulation and the processes in the Arctic Mediterranean, how our present knowledge has developed, and presents recent changes caused by a gradually warmer global climate. The Arctic Mediterranean Sea has been intensively studied in recent years, especially during the fourth International Polar Year, 2007-09, and we have become increasingly aware of the changes presently taking place. This book collects and presents newly acquired knowledge and sets it in perspective to previous studies. Authored by a world-renowned leader in the field, this book explores the role of this small but important sea in the global oceanic circulation and climate-a must-read for researchers and students in the fields of oceanography and climate science.

Non-invasive Brain Stimulation (NIBS) in Neurodevelopmental Disorders, Volume 264 presents the latest updates on recent techniques used to examine the potential treatment of psychiatric and neurological disorders in adults. In this special issue, the book's authors and contributors provide a unique focus on the potential effects of non-invasive brain stimulation. Topics cover a range of reviews, opinions, methodologies, original research articles, and suggestions on how to better translate scientific knowledge into practice. This new release will help guide basic research and the development of therapeutic interventions for children and adolescents who suffer from neurodevelopmental disorders.

Myxomycetes: Biology, Systematics, Biogeography and Ecology, Second Edition provides a complete collection of general and technical information on myxomycetes microorganisms. Its broad scope takes an integrated approach, considering a number of important aspects surrounding their genetics and molecular phylogeny. The book treats myxomycetes as a distinct group from fungi and includes molecular information that discusses systematics and evolutionary pathways. Written and developed by an international team of specialists, this second edition contains updated information on all aspects of myxomycetes. It incorporates relevant and new material on current barcoding developments, plasmodial network experimentation, and non-STEM disciplinary assimilation of myxomycete information. This book is a unique and authoritative resource for researchers in organismal biology and ecology disciplines, as well as students and academics in biology, ecology, microbiology, and similar subject areas. Cover image used with permission from Steve Young Photography

Recent Highlights in the Discovery and Optimization of Crop Protection Products highlights the most prominent, recent results in the search for safe and effective new crop protection products. With a focus on the design, synthesis, optimization and/or structure-activity relationships of new chemistries targeting insect, disease, weed, nematode, vector and animal parasite control, the book also includes recent developments in crop enhancement chemistries and new approaches to crop protection products. The inclusion of information on testing tools, green chemistry approaches, and the latest discovery tools, like modeling, structure-based design, and testing tools makes this volume complete. Based on key presentations given at the 14th International IUPAC conference on Crop Protection, May 19-24, 2019 in Ghent, Belgium, this book includes the many exciting new discoveries and findings reported. It is designed to inspire additional research and advancement in the field.

Advances in Agronomy, Volume 169, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

Advances in Agronomy, Volume 168, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

Written by leading experts in their respective fields, Principles and Applications of Soil Microbiology 3e, provides a comprehensive, balanced introduction to soil microbiology, and captures the rapid advances in the field such as recent discoveries regarding habitats and organisms, microbially mediated transformations, and applied environmental topics. Carefully edited for ease of reading, it aids users by providing an excellent multi-authored reference, the type of book that is continually used in the field. Background information is provided in the first part of the book for ease of comprehension. The following chapters then describe such fundamental topics as soil environment and microbial processes, microbial groups and their interactions, and thoroughly addresses critical nutrient cycles and important environmental and agricultural applications. An excellent textbook and desk reference, Principles and Applications of Soil Microbiology, 3e, provides readers with broad, foundational coverage of the vast array of microorganisms that live in soil and the major biogeochemical processes they control. Soil scientists, environmental scientists, and others, including soil health and conservation specialists, will find this material invaluable for understanding the amazingly diverse world of soil microbiology, managing agricultural and environmental systems, and formulating environmental policy.

Advances in Botanical Research: Past, Current and Future Topics, Volume 100 in the Advances in Botanical Research series, celebrates a remarkable achievement as 100 volumes have now been published, with several others being prepared. New chapters in this monumental release include Editorial activities for Advances in Botanical Research, Revisiting ABR editing in the period 2006-2012: An exciting experience with Jean-Claude Kader, A tribute to the scientific contributions of Pierre Gadal and his laboratory, Evolution of Bacterial Phototrophy, Algae for Global Sustainability, Genomics of cyanobacteria: New insights and lessons for shaping our future, An overview of the root-knot-nematode compatible interaction, and more.

Sometimes history seems like a laundry list of malevolent monarchs, pompous presidents and dastardly dictators. But are they really the ones in the driving seat? Sapiens: A Graphic History – The Masters of History takes us on an immersive and hilarious ride through the human past to discover the forces that change our world, bring us together, and – just as often – tear us apart.

Grab a front-row seat to the greatest show on earth and explore the rise of money, religion and empire. Join our fabulous host Heroda Tush, as she wonders: which historical superhero will display the power to make civilisations rise and fall? Will Mr Random prove that luck and circumstance prevail? Will Lady Empire convince us of the irrefutable shaping force of conquerors? Or will Clashwoman beat them all to greatness by reminding us of the endless confrontations that seem to forever plague our species?

In this next volume of the bestselling graphic series, Yuval Noah Harari, David Vandermeulen and Daniel Casanave continue to present the complicated story of humankind with wit, empathy and originality. Alongside the unlikely cast of new characters, we are rejoined by the familiar faces of Yuval, Zoe, Professor Saraswati, Bill and Cindy (now Romans), Skyman and Captain Dollar. As they travel through time, space and human drama in search of truth, it's impossible not to wonder: why can’t we all just get along?

This third instalment in the Sapiens: A Graphic History series is an engaging, insightful, and colourful retelling of the story of humankind for curious minds of all ages, and can be browsed through on its own or read in sequence with Volumes One and Two.

Wild Germplasm for Genetic Improvement in Crop Plants addresses the need for an integrated reference on a wide variety of crop plants, facilitating comparison and contrast, as well as providing relevant relationships for future research and development. The book presents the genetic and natural history value of wild relatives, covers what wild relatives exist, explores the existing knowledge regarding specific relatives and the research surrounding them and identifies knowledge gaps. As understanding the role of crop wild relatives in plant breeding expands the genetic pool for abiotic and biotic stress resistance, this is an ideal reference on this important topic.

Wood Degradation and Ligninolytic Fungi, Volume 99 summarizes current knowledge on wood degradation by fungi. Chapters in this new release include Intracellular detoxification strategies of lignolytic fungi, Cell signaling during wood degradation, Evolution of ligninolytic systems in fungi, Diversity and distribution of lignolytic fungi, Fungal catalysts for lignin valorization: applied aspects, Expression of fungal lignocellulolytic genes in the environment, Wood degradation in grapevine disease, Imaging wood degradation, Lignin degradation by ascomycetes, and more. The increasing interest for wood decaying fungi over the past few years has sparked great potential for their use in biomass valorization, their important function in global carbon cycle, and for the damages they can cause on wood materials, hence this new release includes updates on these and related topics.

Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Preparing a Workforce for the New Blue Economy: People, Products and Policies discusses the Blue Economy, how the industry will develop, and how to train the next generation. The book considers the use of big data, key skillsets, training undergraduate and graduate students, the Transition Assistance Program (TAP) in the US, economic opportunities in African coastal countries, and governmental agencies, non-profits and NGO's. Finally, a broad range of case studies are provided, covering oil spills, commercial fishing, data protection and harvesting, sustainability and weather forecasting, all presented to highlight the educational requirements of the workforce and potential economic opportunities.

Inoculating Cities: Case Studies of Urban Pandemic Preparedness begins with a brief historical description of infectious disease outbreaks in cities as well as an overview of infectious disease outbreaks since 2000 that hold profound implications for cities and urban environments - such as severe acute respiratory syndrome (SARS) in 2003, H1N1 influenza in 2009, Ebola virus in 2014, Zika virus in 2015, and more recently, COVID-19 in 2020. Each of these outbreaks affected different geographies of the world and underscored the importance of urban pandemic preparedness or urban health security as a means of mitigating the threats posed by infectious diseases. This book describes several of the characteristics of cities that make them uniquely vulnerable to infectious disease threats which include, but are not limited to, their population density, population diversity, internal and external population movements, and inequalities in cities. Finally, the book discusses frameworks and capacities that are essential for preparing cities to prevent, detect, and respond to infectious disease outbreaks. With contributions from experts and researchers with first-hand experiences with infectious disease outbreaks, their impact on the management of disease, and pandemic preparedness in progressively urban societies, Inoculating Cities addresses the unique threats infectious diseases pose to urban environments and surveys innovative models that cities are using to combat these threats.