Protozoa may be found in almost every aquatic habitat, each containing dozens of species. The diversity can provide invaluable insights into the nature of the habitat. Protozoa can thus be used to illustrate biological principles. This colour guide makes the identification of individual protozoa easily accessible to students and professionals and provides information on protozoan communities found in different environments by means of a wealth of colour photomicrographs supported by original and detailed line drawings and concise text. The guide has been welcomed by professional practitioners, researchers and instructors, by graduate, undergraduate and secondary level students, in a wide range of disciplines, for its clarity in providing a logical system for learning and recognition, the first step towards understanding and using the protozoan community as a biological indicator of environmental change, pollution and contamination.

The use of silver as an antibacterial agent has been known for thousands of years. This effect can be amplified by simply reducing the size of silver particles to the nanoscale, with an added advantage of reduction in cost and toxicity. Application of silver nanoparticles to textiles can bring considerable advantages, especially for materials that cannot be washed daily or medical support materials. This book describes a novel synthesis method that the author calls "in situ," in which these nanoparticles are obtained directly on materials. The method is simple and easy to apply and can also be considered green because the reducing agent involved is ascorbic acid, commonly known as vitamin C. It neither requires special modifications in the industrial equipment nor special pressure or temperature conditions. It can be used to grow other metals or metal oxides on a material. The book showcases studies carried out on silver nanoparticles by the author over several years, not only in terms of the synthesis but also the morphological characterization of the substrate to which they were applied. It exhibits SEM images displaying the homogeneity of the silver coating, highlighting that sometimes the simplest way is the best way.

A BOOK OF THE YEAR GUARDIAN, THE ECONOMIST, NEW STATESMAN, FINANCIAL TIMES, BLOOMBERG Anil Seth's radical new theory of consciousness challenges our understanding of perception and reality, doing for brain science what Dawkins did for evolutionary biology. 'A brilliant beast of a book.' DAVID BYRNE 'Hugely important.' JIM AL-KHALILI 'Masterly . . . An exhilarating book: a vast-ranging, phenomenal achievement that will undoubtedly become a seminal text.' GAIA VINCE, GUARDIAN Being You is not as simple as it sounds. Somehow, within each of our brains, billions of neurons work to create our conscious experience. How does this happen? Why do we experience life in the first person? After over twenty years researching the brain, world-renowned neuroscientist Anil Seth puts forward a radical new theory of consciousness and self. His unique theory of what it means to 'be you' challenges our understanding of perception and reality and it turns what you thought you knew about yourself on its head. 'Seth thinks clearly and sharply on one of the hardest problems of science and philosophy, cutting through weeds with a scientist's mind and a storyteller's skill.' ADAM RUTHERFORD 'A page-turner and a mind-blower . . . Beautifully written, crystal clear, deeply insightful.' DAVID EAGLEMAN 'If you read one book about conciousness, it must be Seth's. JULIAN BAGGINI, WALL STREET JOURNAL 'Amazing.' RUSSELL BRAND 'Gripping.' ALEX GARLAND 'I loved it.' MICHAEL POLLAN 'Fascinating.' FINANCIAL TIMES 'Awe-inspring.' NEW STATESMAN 'Brilliant.' CLAIRE TOMALIN, NEW YORK TIMES

From a leading crisis management expert, a breakthrough book about performance under pressure that will change the way you think about stress Upshift 1. a movement of a variable to a higher level e.g. of performance, growth, frequency. When we experience too much stress, we often feel like shutting down and escaping the source. Neurologists call this 'downshifting', where your thinking shifts from the cognitive and creative areas in the brain to the domains associated with survival. But with too little stress, we become disengaged and apathetic. So what happens in the middle zone - when we experience what psychologists call positive stress - and how can we best make use of it? In Upshift, international thought leader Ben Ramalingam takes readers on an epic journey from early humans' survival of the ice age to present times in our inescapable, pernicious and ever-shifting digital landscape. You will hear remarkable stories from a vast range of backgrounds, including scientists, gamers, performers and artists, athletes and health professionals and everyday people, all of whom carved new routes around perceived barriers using their powers to upshift. Whether discussing how city commuters navigate train cancellations to how astronauts deal with life-threatening incidents, Ramalingam presents a fascinating argument that we all have the power to innovate, whether or not we identify ourselves as creative or extraordinary. In a runaway world that is an engine for perpetual crisis, Upshift is not only an essential toolkit for survival, it is a roadmap for positive, and potentially life-changing transformation and influence. You don't have to shut down - you can upshift.

"[This] book will convince you that forgetting helps you remember and distractions can make you more creative." -Adam Grant, New York Times bestselling author of Originals and Give and Take, and host of TED's WorkLife podcast "Illuminating, and a joy to read, [Scatterbrain] offers ... a refreshingly accessible and relatable take on the brain's inner workings that should appeal to both science buffs and casual readers." -Publishers Weekly (Starred Review) In this mind-bending book, an esteemed neuroscientist explains why perfectionism is pointless-and argues that mistakes, missteps, and flaws are the keys to success. Remember that time you screwed up simple math or forgot the name of your favorite song? What if someone told you that such embarrassing "brain farts" are actually secret weapons, proof of your superiority to computers and AI? In Scatterbrain, we learn that boredom awakens the muse, distractions spark creativity, and misjudging time creates valuable memories, among other benefits of our faulty minds. Throughout, award-winning neuroscientist Henning Beck's hilarious asides and brain-boosting advice make for delightful reading of the most cutting-edge neuroscience our brains will (maybe never) remember.

THE NEW YORK TIMES AND SUNDAY TIMES BESTSELLER FROM THE AUTHOR OF THE ORGANIZED MIND 'Everyone we know needs this remarkable book ... Essential for the rest of your life' Daniel H. Pink, author of When and Drive' 'The secrets of ageing well ... a serious, evidence-based guide to what really works and why' Sunday Times ____________________________________________ We have long been encouraged to think of old age as synonymous with a decline in skills. Yet recent studies show that our decision making improves as we age, and our happiness levels peak in our eighties. What really happens to our brains as we get older? In The Changing Mind (published in America as Successful Aging), neuroscientist and internationally bestselling author Daniel Levitin invites us to dramatically shift our understanding of aging, demonstrating the many benefits of growing older. He draws on cutting-edge research to offer realistic guidelines and practical tips for readers to follow during every decade of life, showing us we all can learn from those who age joyously. Find out: -Why the story that older people don't need as many hours of sleep is a myth -What part environment, behaviour and luck play in how our brains age -How to increase the proportion of your life span spent in good health and decrease the time you spend sick -What you can do to maintain strength of body, mind and spirit whilst coping with the limitations of aging Combining science and storytelling, The Changing Mind is a radically new way to think about aging. 'Read this book. Wise, sensitive, and insightful' David Eagleman, author of The Brain 'A comprehensive and fascinating insight into the evolving human brain. This book could change your life' Professor Stephen Westaby, author of Fragile Lives

'Wendy Wood is the world's foremost expert in the field, and this book is essential' - Angela Duckworth, bestselling author of Grit. What if you could harness the extraordinary power of your unconscious mind, which already determines so much of what you do, to achieve your goals? Shockingly, we spend nearly half our day repeating things we've done in the past without thinking about them. How we respond to the people around us; the way we conduct ourselves in meetings; what we buy; when and how we exercise, eat and drink - a truly remarkable number of things we do every day, we do by habit. And yet, whenever we want to change something about ourselves, we rely on willpower alone. We hope that our determination and intention will be enough to effect positive change. And that is why almost all of us fail. Professor Wendy Wood is the world's foremost expert on habits. By drawing on three decades of original research, she explains the fascinating science of how we form habits and provides the key to unlocking our habitual mind in order to make the changes we seek. Combining a potent mix of neuroscience, case studies and experiments conducted in her lab, Good Habits, Bad Habits is a comprehensive, accessible and highly practical book that will change the way you think about almost every aspect of your life.

The evolution of a classic The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focuses on genetic analysis, quantitative problem solving, and experimentation continue in this new edition while incorporating robust updates to the science. Introduction to Genetic Analysis is now supported in Achieve, Macmillan's new online learning platform. Achieve is the culmination of years of development work put toward creating the most powerful online learning tool for biology students. It houses all of our renowned assessments, multimedia assets, e-books, and instructor resources in a powerful new platform.

'A funny and beautifully written welcome to the enigmatic, weird and wonderful world of wasps' DAVE GOULSON, author of SILENT EARTH There may be no insect with a worse reputation than the wasp, and none guarding so many undiscovered wonders. Where bees and ants have long been the darlings of the insect world, wasps are much older, cleverer and more diverse. They are the bee's evolutionary ancestors - flying 100 million years earlier - and today they are just as essential for the survival of our environment. A bee, ecologist Professor Seirian Sumner argues, is just a wasp that has forgotten how to hunt. For readers of Entangled Life, Other Minds and The Gospel of Eels, this is a book to upturn your expectations about one overlooked animal and the wider architecture of our natural world. With endless surprises, this book might teach you about the wasps that spend their entire lives sealed inside a fig, about stinging wasps, about parasitic wasps, about wasps that turn cockroaches into living zombies, about how wasps taught us to make paper. It offers up a maligned insect in all its diverse, unexpected splendour; as both predator and pollinator, the wasp is an essential pest controller worldwide. Inside their sophisticated social worlds is the best model we have for the earth's major evolutionary transitions. In their understudied biology are clues to progressing medicine, including a possible cure for cancer. The closer you look at these spurned, winged insects - both custodians and bouncers of our planet - the more you see. Their secrets have so far gone mostly untapped, but the potential of the wasp is endless.

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.

The threat of climate displacement looms large over a growing number of countries. Based on the more than six years of work by Displacement Solutions in ten climate-affected countries, academic work on displacement and climate adaptation, and the country-level efforts of civil society groups in several frontline countries, this report explores the key contention that land will be at the core of any major strategy aimed at preventing and resolving climate displacement. This innovative and timely volume coordinated and edited by the Founder of Displacement Solutions, Scott Leckie, examines a range of legal, policy and practical issues relating to the role of land in actively addressing the displacement consequences of climate change. It reveals the inevitable truth that climate displacement is already underway and being tackled in countries such as Bangladesh, Kiribati, Papua New Guinea, Solomon Islands, Tuvalu and the United States, and proposes a series of possible land solution tools that can be employed to protect the rights of people and communities everywhere should they be forced to flee the places they call home.

This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies.

Practical tools and tips to lead a healthy and productive life The brain is the basis of everything we do: how we behave, communicate, feel, remember, pay attention, create, influence and decide. Why We Do What We Do combines scientific research with concrete examples and illustrative stories to clarify the complex mechanisms of the human brain. It offers valuable insights into how our brain works every day, at home and at work, and provides practical ideas and tips to help us lead happy, healthy and productive lives. - Learn about how your brain functions - Find out how emotions can be overcome or last a lifetime - Access your brain's natural ability to focus and concentrate - Think creatively The thoughts you have and the words that you speak all have an effect on your neural architecture -- and this book explains what that means in a way you can understand.

Twin Research: Biology, Health, Epigenetics, and Psychology is a comprehensive, applied resource in twinning and twin studies that is grounded in the most impactful findings from twin research in recent years. While targeted to undergraduate and graduate students, this compendium will prove a valuable resource for scholars already familiar with twin studies, as well as those coming to the field for the first time. Here, more than forty experts across an array of disciplines examine twinning and twin research methodologies from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods, family and parenting aspects of twinning, twin studies as applied across various disease areas and medical specialties, genetic and epigenetic determinants of differentiation, and academic, neurological and cognitive development. The presentation of existing studies and methods instruction empowers students and researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions.

Microbiome Therapeutics: Personalized Therapy Beyond Conventional Approaches addresses the current knowledge and landscape of microbiome therapeutics, providing an overview of existing applications in health and disease as well as potential future directions of microbiome modulations and subsequent translation to the global industry and market. This important reference provides the most current status of microbiome therapeutics as well as possible future perspectives through coverage of topics including the application of microbiome therapeutics; various additive, subtractive and modulatory approaches; microbiome composition of health and diseases, insights into live bio-therapeutics and the clinical data supporting their efficacy. Case studies are provided throughout the book to further define, describe and evaluate microbiome therapeutics success and failure.

First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate 'things' in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.

Provides exclusive material on refractories Discusses detailed descriptions of different shaped and unshaped refractories Uses phase diagrams for better understanding of concepts Explores details on testing and specifications including thermochemical and corrosion behaviour Includes a separate chapter on trends of refractories and other issues

Image synthesis across and within medical imaging modalities is an active area of research with broad applications in radiology and radiation oncology. This book covers the principles and methods of medical image synthesis, along with state-of-the-art research. First, various traditional non-learning-based, traditional machine-learning-based, and recent deep-learning-based medical image synthesis methods are reviewed. Second, specific applications of different inter- and intra-modality image synthesis tasks and of synthetic image-aided segmentation and registration are introduced and summarized, listing and highlighting the proposed methods, study designs, and reported performances with the related clinical applications of representative studies. Third, the clinical usages of medical image synthesis, such as treatment planning and image-guided adaptive radiotherapy, are discussed. Last, the limitations and current challenges of various medical synthesis applications are explored, along with future trends and potential solutions to solve these difficulties. The benefits of medical image synthesis have sparked growing interest in a number of advanced clinical applications, such as magnetic resonance imaging (MRI)-only radiation therapy treatment planning and positron emission tomography (PET)/MRI scanning. This book will be a comprehensive and exciting resource for undergraduates, graduates, researchers, and practitioners.

Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism.

Get Insight on the Function of Supercomplexes in Biological Systems Redox Proteins in Supercomplexes and Signalosomes is one of the first books to explore the key role played by redox proteins and their interaction network in a wide range of essential cellular processes in all domains of life. The book explains how the mitochondrial respiratory chain is dynamically organized in supercomplexes even under physiological conditions. It also addresses the impact of supercomplex assembly on mitochondrial morphology, physiology, and biogenesis to shed light on the molecular mechanisms of pathological situations, including aging. Discover the Connection between Bioenergetic Supercomplexes and Signalosomes Compiling state-of-the-art research from leading practitioners in the field, this book gives you guidance on dealing with these biological systems in your investigations. The book shows that supercomplexes and signalosomes provide the link between reductive and systems biology, which enables us to understand how the molecular properties of individual macromolecular components trigger cellular function.

Life innovates constantly, producing perfectly adapted species – but there’s a catch.  Many animals and plants eke out seemingly unremarkable lives. Passive, constrained, modest, threatened. Then, in a blink of evolutionary time, they flourish spectacularly. Once we start to look, these ‘sleeping beauties’ crop up everywhere. But why? Looking at the book of life, from apex predators to keystone crops, and informed by his own cutting-edge experiments, renowned scientist Andreas Wagner demonstrates that innovations can come frequently and cheaply to nature, well before they are needed. We have found prehistoric bacteria that harbour the remarkable ability to fight off 21st-century antibiotics. And human history fits the pattern too, as life-changing technologies are invented only to be forgotten, languishing in the shadows before they finally take off. In probing the mysteries of these sleeping beauties, Wagner reveals a crucial part of nature’s rich and strange tapestry.

Describes landmark experiments in cell biology and biochemistry Discusses the "How" and "Why" of historically important experiments Includes primary, original data and graphs Emphasizes biological techniques, which helps understand how many of the experiments performed were possible. Documents, chronologically, how each result fed into the next experiments.

You could be a genius . . . In The Genius Within, award-winning science writer David Adam reveals how frontier neuroscience can enhance your intelligence - making you smarter, sharper and brighter than you ever thought you could be. What if you have more intelligence than you realize? What if there is a genius inside you, just waiting to be released? And what if the route to better brain power is not hard work or thousands of hours of practice but to simply swallow a pill? Sunday Times bestseller Dr David Adam, author of The Man Who Couldn't Stop, explores the ground-breaking neuroscience of cognitive enhancement that is changing the way the brain and the mind works - to make it better, sharper, more focused and, yes, more intelligent. Sharing his own experiments with revolutionary smart drugs and electrical brain stimulation, he delves into the sinister history of intelligence tests, meets savants and brain hackers and reveals how he boosted his own IQ to cheat his way into Mensa. Going to the heart of how we consider, measure and judge mental ability, The Genius Within asks difficult questions about the science that could rank and define us, and inevitably shape our future. 'Witty, sharp and enlightening . . . This book will make you smarter' Adam Rutherford, science writer and presenter of BBC Radio 4's Inside Science.

A History of Science in Society is a concise overview that introduces complex ideas in a non-technical fashion. Ede and Cormack trace the history of the changing place of science in society and explore the link between the pursuit of knowledge and the desire to make that knowledge useful. Volume I covers the origins of natural philosophy in the ancient world to the Scientific Revolution. New topics in this edition include astronomy and mathematics in ancient Mayan society, science and technology in ancient India and China, and Islamic cartography. New "Connections" features provide in-depth exploration of the ways science and society interconnect. The text is accompanied by 27 colour maps and diagrams, and 4 colour plates highlighting key concepts and events. Essay questions, chapter timelines, a further readings section, and an index provide additional support for students. A companion reader edited by the authors, A History of Science in Society: A Reader, is also available.